Zurück zum Zitat Chambless LE, Heiss G, Folsom AR, Rosamond W, Szklo M, Sharrett AR, Clegg LX (1997) Association of coronary heart disease incidence with carotid arterial wall thickness and major risk factors: the Atherosclerosis Risk in Communities (ARIC) Study, 1987–1993. Am J Epidemiol 146:483–494CrossRefPubMed Chambless LE, Heiss G, Folsom AR, Rosamond W, Szklo M, Sharrett AR, Clegg LX (1997) Association of coronary heart disease incidence with carotid arterial wall thickness and major risk factors: the Atherosclerosis Risk in Communities (ARIC) Study, 1987–1993. Am J Epidemiol 146:483–494CrossRefPubMed

Zurück zum Zitat Fichet J, de Labriolle A, Giraudeau B, Arbeille P, Charbonnier B (2008) Reducing risk of stroke in patients with acute coronary syndrome: is screening for asymptomatic carotid disease useful? Heart Vessels 23:397–402CrossRefPubMed Fichet J, de Labriolle A, Giraudeau B, Arbeille P, Charbonnier B (2008) Reducing risk of stroke in patients with acute coronary syndrome: is screening for asymptomatic carotid disease useful? Heart Vessels 23:397–402CrossRefPubMed

Zurück zum Zitat Chan SY, Mancini GB, Kuramoto L, Schulzer M, Frolich J, Ignaszewski A (2003) The prognostic importance of endothelial dysfunction and carotid atheroma burden in patients with coronary artery disease. J Am Coll Cardiol 42:1037–1043CrossRefPubMed Chan SY, Mancini GB, Kuramoto L, Schulzer M, Frolich J, Ignaszewski A (2003) The prognostic importance of endothelial dysfunction and carotid atheroma burden in patients with coronary artery disease. J Am Coll Cardiol 42:1037–1043CrossRefPubMed

Zurück zum Zitat Kuller L, Borhani N, Furberg C, Gardin J, Manolio T, O’Leary D, Psalty B, Robbins J (1994) Prevalence of subclinical atherosclerosis and cardiovascular disease and association with risk factors in the Cardiovascular Health Study. Am J Epidemiol 139:1164–1179PubMed Kuller L, Borhani N, Furberg C, Gardin J, Manolio T, O’Leary D, Psalty B, Robbins J (1994) Prevalence of subclinical atherosclerosis and cardiovascular disease and association with risk factors in the Cardiovascular Health Study. Am J Epidemiol 139:1164–1179PubMed

Zurück zum Zitat Pierdomenico SD, Mancini M, Cuccurullo C, Guglielmi MD, Pierdomenico AM, Di Nicola M, Di Carlo S, Lapenna D, Cuccurullo F (2013) Prediction of carotid plaques in hypertensive patients by risk factors, left ventricular hypertrophy, and epicardial adipose tissue thickness. Heart Vessels 28:277–283CrossRefPubMed Pierdomenico SD, Mancini M, Cuccurullo C, Guglielmi MD, Pierdomenico AM, Di Nicola M, Di Carlo S, Lapenna D, Cuccurullo F (2013) Prediction of carotid plaques in hypertensive patients by risk factors, left ventricular hypertrophy, and epicardial adipose tissue thickness. Heart Vessels 28:277–283CrossRefPubMed

Zurück zum Zitat O’Leary DH, Polak JF, Kronmal RA, Manolio TA, Burke GL, Wolfson SK Jr (1999) Carotid-artery intima and media thickness as a risk factor for myocardial infarction and stroke in older adults: Cardiovascular Health Study. N Engl J Med 340:14–22CrossRefPubMed O’Leary DH, Polak JF, Kronmal RA, Manolio TA, Burke GL, Wolfson SK Jr (1999) Carotid-artery intima and media thickness as a risk factor for myocardial infarction and stroke in older adults: Cardiovascular Health Study. N Engl J Med 340:14–22CrossRefPubMed

Zurück zum Zitat Belcaro G, Nicolaides AN, Ramaswami G, Cesarone MR, De Sanctis M, Incandela L, Ferrari P, Geroulakos G, Barsotti A, Griffin M, Dhanjil S, Sabetai M, Bucci M, Martines G (2001) Carotid and femoral ultrasound morphology screening and cardiovascular events in low risk subjects: a 10-year follow-up study (the CAFESCAVE study). Atherosclerosis 156:379–387CrossRefPubMed Belcaro G, Nicolaides AN, Ramaswami G, Cesarone MR, De Sanctis M, Incandela L, Ferrari P, Geroulakos G, Barsotti A, Griffin M, Dhanjil S, Sabetai M, Bucci M, Martines G (2001) Carotid and femoral ultrasound morphology screening and cardiovascular events in low risk subjects: a 10-year follow-up study (the CAFESCAVE study). Atherosclerosis 156:379–387CrossRefPubMed

Zurück zum Zitat Salonen R, Nyyssonen K, Porkkala-Sarataho E, Salonen JT (1995) The Kuopio Atherosclerosis Prevention Study (KAPS): effect of pravastatin treatment on lipids, oxidation resistance of lipoproteins, and atherosclerotic progression. Am J Cardiol 76:34C–39CCrossRefPubMed Salonen R, Nyyssonen K, Porkkala-Sarataho E, Salonen JT (1995) The Kuopio Atherosclerosis Prevention Study (KAPS): effect of pravastatin treatment on lipids, oxidation resistance of lipoproteins, and atherosclerotic progression. Am J Cardiol 76:34C–39CCrossRefPubMed

Zurück zum Zitat Iannuzzi A, Licenziati MR, Vacca M, De Marco D, Cinquegrana G, Laccetti M, Bresciani A, Covetti G, Iannuzzo G, Rubba P, Parillo M (2009) Comparison of two diets of varying glycemic index on carotid subclinical atherosclerosis in obese children. Heart Vessels 24:419–424CrossRefPubMed Iannuzzi A, Licenziati MR, Vacca M, De Marco D, Cinquegrana G, Laccetti M, Bresciani A, Covetti G, Iannuzzo G, Rubba P, Parillo M (2009) Comparison of two diets of varying glycemic index on carotid subclinical atherosclerosis in obese children. Heart Vessels 24:419–424CrossRefPubMed

Zurück zum Zitat Okumura K, Tsukamoto H, Tsuboi H, Hirayama H, Kamiya H, Watarai M, Ishiki R, Murohara T; on behalf of the Samurai Study Investigators (2014) High HDL cholesterol level after treatment with pitavastatin is an important factor for regression in carotid intima-media thickness. Heart Vessels. doi:10.1007/s00380-013-0466-3 Okumura K, Tsukamoto H, Tsuboi H, Hirayama H, Kamiya H, Watarai M, Ishiki R, Murohara T; on behalf of the Samurai Study Investigators (2014) High HDL cholesterol level after treatment with pitavastatin is an important factor for regression in carotid intima-media thickness. Heart Vessels. doi:10.​1007/​s00380-013-0466-3

Zurück zum Zitat Gepner AD, Keevil JG, Wyman RA, Korcarz CE, Aeschlimann SE, Busse KL, Stein JH (2006) Use of carotid intima-media thickness and vascular age to modify cardiovascular risk prediction. J Am Soc Echocardiogr 19:1170–1174CrossRefPubMed Gepner AD, Keevil JG, Wyman RA, Korcarz CE, Aeschlimann SE, Busse KL, Stein JH (2006) Use of carotid intima-media thickness and vascular age to modify cardiovascular risk prediction. J Am Soc Echocardiogr 19:1170–1174CrossRefPubMed

Zurück zum Zitat Honda O, Sugiyama S, Kugiyama K, Fukushima H, Nakamura S, Koide S, Kojima S, Hirai N, Kawano H, Soejima H, Sakamoto T, Yoshimura M, Ogawa H (2004) Echolucent carotid plaques predict future coronary events in patients with coronary artery disease. J Am Coll Cardiol 43:1177–1184CrossRefPubMed Honda O, Sugiyama S, Kugiyama K, Fukushima H, Nakamura S, Koide S, Kojima S, Hirai N, Kawano H, Soejima H, Sakamoto T, Yoshimura M, Ogawa H (2004) Echolucent carotid plaques predict future coronary events in patients with coronary artery disease. J Am Coll Cardiol 43:1177–1184CrossRefPubMed

Zurück zum Zitat Nasr N, Pavy-Le Traon A, Larrue V (2005) Baroreflex sensitivity is impaired in bilateral carotid atherosclerosis. Stroke 36:1891–1895CrossRefPubMed Nasr N, Pavy-Le Traon A, Larrue V (2005) Baroreflex sensitivity is impaired in bilateral carotid atherosclerosis. Stroke 36:1891–1895CrossRefPubMed

Zurück zum Zitat Latinen T, Hartikainen J, Vanninen E, Niskanen L, Geelen G, Länsimies E (1985) Age and gender dependency of baroreflex sensitivity in healthy subjects. J Appl Physiol (1998) 84:576–583 Latinen T, Hartikainen J, Vanninen E, Niskanen L, Geelen G, Länsimies E (1985) Age and gender dependency of baroreflex sensitivity in healthy subjects. J Appl Physiol (1998) 84:576–583

Zurück zum Zitat Head GA (1995) Baroreflexes and cardiovascular regulation in hypertension. J Cardiovasc Pharmacol 26(suppl 2):S7–S16CrossRefPubMed Head GA (1995) Baroreflexes and cardiovascular regulation in hypertension. J Cardiovasc Pharmacol 26(suppl 2):S7–S16CrossRefPubMed

Zurück zum Zitat McDowell TS, Chapleau MW, Hajduczok G, Abboud FM (1994) Baroreflex dysfunction in diabetes mellitus. I. Selective impairment of parasympathetic control of heart rate. Am J Physiol 266:H235–H243PubMed McDowell TS, Chapleau MW, Hajduczok G, Abboud FM (1994) Baroreflex dysfunction in diabetes mellitus. I. Selective impairment of parasympathetic control of heart rate. Am J Physiol 266:H235–H243PubMed

Zurück zum Zitat Katsube Y, Saro H, Naka M, Kim BH, Kinoshita N, Koretsune Y, Hori M (1996) Decreased baroreflex sensitivity in patients with stable coronary artery disease is correlated with the severity of coronary narrowing. Am J Cardiol 78:1007–1010CrossRefPubMed Katsube Y, Saro H, Naka M, Kim BH, Kinoshita N, Koretsune Y, Hori M (1996) Decreased baroreflex sensitivity in patients with stable coronary artery disease is correlated with the severity of coronary narrowing. Am J Cardiol 78:1007–1010CrossRefPubMed

Zurück zum Zitat Fukuma N, Kato K, Munakata K, Hayashi H, Kato Y, Aisu N, Takahashi H, Mabuchi K, Mizuno K (2012) Baroreflex mechanisms and response to exercise in patients with heart disease. Clin Physiol Funct Imaging 32:305–309PubMedCentralCrossRefPubMed Fukuma N, Kato K, Munakata K, Hayashi H, Kato Y, Aisu N, Takahashi H, Mabuchi K, Mizuno K (2012) Baroreflex mechanisms and response to exercise in patients with heart disease. Clin Physiol Funct Imaging 32:305–309PubMedCentralCrossRefPubMed

Zurück zum Zitat Balady GJ, Larson MG, Vasan RS, Leip EP, O’Donnell CJ, Levy D (2004) Usefulness of exercise testing in the prediction of coronary disease risk among asymptomatic persons as a function of the Framingham risk score. Circulation 110:1920–1925CrossRefPubMed Balady GJ, Larson MG, Vasan RS, Leip EP, O’Donnell CJ, Levy D (2004) Usefulness of exercise testing in the prediction of coronary disease risk among asymptomatic persons as a function of the Framingham risk score. Circulation 110:1920–1925CrossRefPubMed

Zurück zum Zitat Brener SJ, Pashkow FJ, Harvey SA, Marwick TH, Thomas JD, Lauer MS (1995) Chronotropic response to exercise predicts angiographic severity in patients with suspected or stable coronary artery disease. Am J Cardiol 76:1228–1232CrossRefPubMed Brener SJ, Pashkow FJ, Harvey SA, Marwick TH, Thomas JD, Lauer MS (1995) Chronotropic response to exercise predicts angiographic severity in patients with suspected or stable coronary artery disease. Am J Cardiol 76:1228–1232CrossRefPubMed

Zurück zum Zitat Lauer MS, Francis GS, Okin PM, Pashkow FJ, Snader CE, Marwick TH (1999) Impaired chronotropic response to exercise stress testing as a predictor of mortality. JAMA 281:524–529CrossRefPubMed Lauer MS, Francis GS, Okin PM, Pashkow FJ, Snader CE, Marwick TH (1999) Impaired chronotropic response to exercise stress testing as a predictor of mortality. JAMA 281:524–529CrossRefPubMed

Zurück zum Zitat Lauer M, Froelicher ES, Williams M, Kligfield P, American Heart Association Council on Clinical Cardiology, Subcommittee on Exercise, Cardiac Rehabilitation, and Prevention (2005) Exercise testing in asymptomatic adults: a statement for professionals from the American Heart Association Council on Clinical Cardiology, Subcommittee on Exercise, Cardiac Rehabilitation, and Prevention. Circulation 112:771–776CrossRefPubMed Lauer M, Froelicher ES, Williams M, Kligfield P, American Heart Association Council on Clinical Cardiology, Subcommittee on Exercise, Cardiac Rehabilitation, and Prevention (2005) Exercise testing in asymptomatic adults: a statement for professionals from the American Heart Association Council on Clinical Cardiology, Subcommittee on Exercise, Cardiac Rehabilitation, and Prevention. Circulation 112:771–776CrossRefPubMed

Zurück zum Zitat Pitsavos CH, Chrysohoou C, Panagiotakos DB, Kokkinos P, Skoumas J, Papaioannou I, Michaelides AP, Singh S, Stefanadis CI (2004) Exercise capacity and heart rate recovery as predictors of coronary heart disease events, in patients with heterozygous familial hypercholesterolemia. Atherosclerosis 173:347–352CrossRefPubMed Pitsavos CH, Chrysohoou C, Panagiotakos DB, Kokkinos P, Skoumas J, Papaioannou I, Michaelides AP, Singh S, Stefanadis CI (2004) Exercise capacity and heart rate recovery as predictors of coronary heart disease events, in patients with heterozygous familial hypercholesterolemia. Atherosclerosis 173:347–352CrossRefPubMed

Zurück zum Zitat Schwartz PJ, La Rovere MT, Vanoli E (1992) Autonomic nervous system and sudden cardiac death: experimental basis and clinical observations for post myocardial infarction risk stratification. Circulation 85(Suppl I):I77–I91PubMed Schwartz PJ, La Rovere MT, Vanoli E (1992) Autonomic nervous system and sudden cardiac death: experimental basis and clinical observations for post myocardial infarction risk stratification. Circulation 85(Suppl I):I77–I91PubMed

Zurück zum Zitat Perk J, De Backer G, Gohlke H, Graham I, Reiner Z, Verschuren M, Albus C, Benlian P, Boysen G, Cifkova R, Deaton C, Ebrahim S, Fisher M, Germano G, Hobbs R, Hoes A, Karadeniz S, Mezzani A, Prescott E, Ryden L, Scherer M, Syvänne M, Scholte op Reimer WJ, Vrints C, Wood D, Zannad F, European Association for Cardiovascular Prevention and Rehabilitation (EACPR), ESC Committee for Practice Guidelines (CPG) (2012) European Guidelines on cardiovascular disease prevention in clinical practice (version 2012). The Fifth Joint Task Force of the European Society of Cardiology and Other Societies on Cardiovascular Disease Prevention in Clinical Practice (constituted by representatives of nine societies and by invited experts). Eur Heart J 33:1635–1701CrossRefPubMed Perk J, De Backer G, Gohlke H, Graham I, Reiner Z, Verschuren M, Albus C, Benlian P, Boysen G, Cifkova R, Deaton C, Ebrahim S, Fisher M, Germano G, Hobbs R, Hoes A, Karadeniz S, Mezzani A, Prescott E, Ryden L, Scherer M, Syvänne M, Scholte op Reimer WJ, Vrints C, Wood D, Zannad F, European Association for Cardiovascular Prevention and Rehabilitation (EACPR), ESC Committee for Practice Guidelines (CPG) (2012) European Guidelines on cardiovascular disease prevention in clinical practice (version 2012). The Fifth Joint Task Force of the European Society of Cardiology and Other Societies on Cardiovascular Disease Prevention in Clinical Practice (constituted by representatives of nine societies and by invited experts). Eur Heart J 33:1635–1701CrossRefPubMed

Zurück zum Zitat Panagiotakos DB, Fitzgerald AP, Pitsavos C, Pipilis A, Graham I, Stefanadis C (2007) Statistical modelling of 10-year fatal cardiovascular disease risk in Greece: the HellenicSCORE (a calibration of the ESC SCORE project). Hellenic J Cardiol 48:55–63PubMed Panagiotakos DB, Fitzgerald AP, Pitsavos C, Pipilis A, Graham I, Stefanadis C (2007) Statistical modelling of 10-year fatal cardiovascular disease risk in Greece: the HellenicSCORE (a calibration of the ESC SCORE project). Hellenic J Cardiol 48:55–63PubMed

Zurück zum Zitat Fletcher GF, Ades PA, Kligfield P, Arena R, Balady GJ, Bittner VA, Coke LA, Fleg JL, Forman DE, Gerber TC, Gulati M, Madan K, Rhodes J, Thompson PD, Williams MA, American Heart Association Exercise, Cardiac Rehabilitation, and Prevention Committee of the Council on Clinical Cardiology, Council on Nutrition, Physical Activity and Metabolism, Council on Cardiovascular and Stroke Nursing, and Council on Epidemiology and Prevention (2013) Exercise standards for testing and training: a scientific statement from the American Heart Association. Circulation 128:873–934CrossRefPubMed Fletcher GF, Ades PA, Kligfield P, Arena R, Balady GJ, Bittner VA, Coke LA, Fleg JL, Forman DE, Gerber TC, Gulati M, Madan K, Rhodes J, Thompson PD, Williams MA, American Heart Association Exercise, Cardiac Rehabilitation, and Prevention Committee of the Council on Clinical Cardiology, Council on Nutrition, Physical Activity and Metabolism, Council on Cardiovascular and Stroke Nursing, and Council on Epidemiology and Prevention (2013) Exercise standards for testing and training: a scientific statement from the American Heart Association. Circulation 128:873–934CrossRefPubMed

Zurück zum Zitat Mancia G, Fagard R, Narkiewicz K, Redon J, Zanchetti A, Böhm M, Christiaens T, Cifkova R, De Backer G, Dominiczak A, Galderisi M, Grobbee DE, Jaarsma T, Kirchhof P, Kjeldsen SE, Laurent S, Manolis AJ, Nilsson PM, Ruilope LM, Schmieder RE, Sirnes PA, Sleight P, Viigimaa M, Waeber B, Zannad F, Redon J, Dominiczak A, Narkiewicz K, Nilsson PM, Burnier M, Viigimaa M, Ambrosioni E, Caufield M, Coca A, Olsen MH, Schmieder RE, Tsioufis C, van de Borne P, Zamorano JL, Achenbach S, Baumgartner H, Bax JJ, Bueno H, Dean V, Deaton C, Erol C, Fagard R, Ferrari R, Hasdai D, Hoes AW, Kirchhof P, Knuuti J, Kolh P, Lancellotti P, Linhart A, Nihoyannopoulos P, Piepoli MF, Ponikowski P, Sirnes PA, Tamargo JL, Tendera M, Torbicki A, Wijns W, Windecker S, Clement DL, Coca A, Gillebert TC, Tendera M, Rosei EA, Ambrosioni E, Anker SD, Bauersachs J, Hitij JB, Caulfield M, De Buyzere M, De Geest S, Derumeaux GA, Erdine S, Farsang C, Funck-Brentano C, Gerc V, Germano G, Gielen S, Haller H, Hoes AW, Jordan J, Kahan T, Komajda M, Lovic D, Mahrholdt H, Olsen MH, Ostergren J, Parati G, Perk J, Polonia J, Popescu BA, Reiner Z, Rydén L, Sirenko Y, Stanton A, Struijker-Boudier H, Tsioufis C, van de Borne P, Vlachopoulos C, Volpe M, Wood DA (2013) 2013 ESH/ESC guidelines for the management of arterial hypertension: the task force for the management of arterial hypertension of the European Society of Hypertension (ESH) and of the European Society of Cardiology (ESC). Eur Heart J 34:2159–2219CrossRefPubMed Mancia G, Fagard R, Narkiewicz K, Redon J, Zanchetti A, Böhm M, Christiaens T, Cifkova R, De Backer G, Dominiczak A, Galderisi M, Grobbee DE, Jaarsma T, Kirchhof P, Kjeldsen SE, Laurent S, Manolis AJ, Nilsson PM, Ruilope LM, Schmieder RE, Sirnes PA, Sleight P, Viigimaa M, Waeber B, Zannad F, Redon J, Dominiczak A, Narkiewicz K, Nilsson PM, Burnier M, Viigimaa M, Ambrosioni E, Caufield M, Coca A, Olsen MH, Schmieder RE, Tsioufis C, van de Borne P, Zamorano JL, Achenbach S, Baumgartner H, Bax JJ, Bueno H, Dean V, Deaton C, Erol C, Fagard R, Ferrari R, Hasdai D, Hoes AW, Kirchhof P, Knuuti J, Kolh P, Lancellotti P, Linhart A, Nihoyannopoulos P, Piepoli MF, Ponikowski P, Sirnes PA, Tamargo JL, Tendera M, Torbicki A, Wijns W, Windecker S, Clement DL, Coca A, Gillebert TC, Tendera M, Rosei EA, Ambrosioni E, Anker SD, Bauersachs J, Hitij JB, Caulfield M, De Buyzere M, De Geest S, Derumeaux GA, Erdine S, Farsang C, Funck-Brentano C, Gerc V, Germano G, Gielen S, Haller H, Hoes AW, Jordan J, Kahan T, Komajda M, Lovic D, Mahrholdt H, Olsen MH, Ostergren J, Parati G, Perk J, Polonia J, Popescu BA, Reiner Z, Rydén L, Sirenko Y, Stanton A, Struijker-Boudier H, Tsioufis C, van de Borne P, Vlachopoulos C, Volpe M, Wood DA (2013) 2013 ESH/ESC guidelines for the management of arterial hypertension: the task force for the management of arterial hypertension of the European Society of Hypertension (ESH) and of the European Society of Cardiology (ESC). Eur Heart J 34:2159–2219CrossRefPubMed

Zurück zum Zitat Reiner Z, Catapano AL, De Backer G, Graham I, Taskinen MR, Wiklund O, Agewall S, Alegria E, Chapman MJ, Durrington P, Erdine S, Halcox J, Hobbs R, Kjekshus J, Filardi PP, Riccardi G, Storey RF, Wood D, ESC/EAS Guidelines for the management of dyslipidaemias: the Task Force for the management of dyslipidaemias of the European Society of Cardiology (ESC) and the European Atherosclerosis Society (EAS) (2011) ESC/EAS Guidelines for the management of dyslipidaemias: the task force for the management of dyslipidaemias of the European Society of Cardiology (ESC) and the European Atherosclerosis Society (EAS). Eur Heart J 32:1769–1818CrossRefPubMed Reiner Z, Catapano AL, De Backer G, Graham I, Taskinen MR, Wiklund O, Agewall S, Alegria E, Chapman MJ, Durrington P, Erdine S, Halcox J, Hobbs R, Kjekshus J, Filardi PP, Riccardi G, Storey RF, Wood D, ESC/EAS Guidelines for the management of dyslipidaemias: the Task Force for the management of dyslipidaemias of the European Society of Cardiology (ESC) and the European Atherosclerosis Society (EAS) (2011) ESC/EAS Guidelines for the management of dyslipidaemias: the task force for the management of dyslipidaemias of the European Society of Cardiology (ESC) and the European Atherosclerosis Society (EAS). Eur Heart J 32:1769–1818CrossRefPubMed

Zurück zum Zitat Papathanasiou G, Georgoudis G, Papandreou M, Spyropoulos P, Georgakopoulos D, Kalfakakou V, Evangelou A (2009) Reliability measures of the short International Physical Activity Questionnaire (IPAQ) in Greek young adults. Hellenic J Cardiol 50:283–294PubMed Papathanasiou G, Georgoudis G, Papandreou M, Spyropoulos P, Georgakopoulos D, Kalfakakou V, Evangelou A (2009) Reliability measures of the short International Physical Activity Questionnaire (IPAQ) in Greek young adults. Hellenic J Cardiol 50:283–294PubMed

Zurück zum Zitat van der Meer IM, Bots ML, Hofman A, del Sol AI, van der Kuip DA, Witteman JC (2004) Predictive value of noninvasive measures of atherosclerosis for incident myocardial infarction: the Rotterdam Study. Circulation 109:1089–1094CrossRefPubMed van der Meer IM, Bots ML, Hofman A, del Sol AI, van der Kuip DA, Witteman JC (2004) Predictive value of noninvasive measures of atherosclerosis for incident myocardial infarction: the Rotterdam Study. Circulation 109:1089–1094CrossRefPubMed

Zurück zum Zitat Dupont WD, Plummer WD (1990) Power and sample size calculations: a review and computer program. Control Clin Trials 11:116–128CrossRefPubMed Dupont WD, Plummer WD (1990) Power and sample size calculations: a review and computer program. Control Clin Trials 11:116–128CrossRefPubMed

Zurück zum Zitat Jae SY, Fernhall B, Heffernan KS, Kang M, Lee MK, Choi YH, Park WH (2006) Chronotropic response to exercise testing is associated with carotid atherosclerosis in healthy middle-aged men. Eur Heart J 27:954–959CrossRefPubMed Jae SY, Fernhall B, Heffernan KS, Kang M, Lee MK, Choi YH, Park WH (2006) Chronotropic response to exercise testing is associated with carotid atherosclerosis in healthy middle-aged men. Eur Heart J 27:954–959CrossRefPubMed

Zurück zum Zitat Greenland P, Smith SC Jr, Grundy SM (2001) Improving coronary heart disease risk assessment in asymptomatic people: role of traditional risk factors and noninvasive cardiovascular tests. Circulation 104:1863–1867CrossRefPubMed Greenland P, Smith SC Jr, Grundy SM (2001) Improving coronary heart disease risk assessment in asymptomatic people: role of traditional risk factors and noninvasive cardiovascular tests. Circulation 104:1863–1867CrossRefPubMed

Zurück zum Zitat Magda SL, Ciobanu AO, Florescu M, Vinereanu D (2013) Comparative reproducibility of the noninvasive ultrasound methods for the assessment of vascular function. Heart Vessels 28:143–150CrossRefPubMed Magda SL, Ciobanu AO, Florescu M, Vinereanu D (2013) Comparative reproducibility of the noninvasive ultrasound methods for the assessment of vascular function. Heart Vessels 28:143–150CrossRefPubMed

Zurück zum Zitat Grundy SM, Pasternak R, Greenland P, Smith S Jr, Fuster V (1999) AHA/ACC scientific statement: assessment of cardiovascular risk by use of multiple-riskfactor assessment equations: a statement for healthcare professionals from the American Heart Association and the American College of Cardiology. J Am Coll Cardiol 34:1348–1359CrossRefPubMed Grundy SM, Pasternak R, Greenland P, Smith S Jr, Fuster V (1999) AHA/ACC scientific statement: assessment of cardiovascular risk by use of multiple-riskfactor assessment equations: a statement for healthcare professionals from the American Heart Association and the American College of Cardiology. J Am Coll Cardiol 34:1348–1359CrossRefPubMed

Zurück zum Zitat Hodis HN, Mack WJ, LaBree L, Selzer RH, Liu CR, Liu CH, Azen SP (1998) The role of carotid arterial intima-media thickness in predicting clinical coronary events. Ann Intern Med 128:262–269CrossRefPubMed Hodis HN, Mack WJ, LaBree L, Selzer RH, Liu CR, Liu CH, Azen SP (1998) The role of carotid arterial intima-media thickness in predicting clinical coronary events. Ann Intern Med 128:262–269CrossRefPubMed

Zurück zum Zitat Simon A, Chironi G, Levenson J (2007) Comparative performance of subclinical atherosclerosis tests in predicting coronary heart disease in asymptomatic individuals. Eur Heart J 28:2967–2971CrossRefPubMed Simon A, Chironi G, Levenson J (2007) Comparative performance of subclinical atherosclerosis tests in predicting coronary heart disease in asymptomatic individuals. Eur Heart J 28:2967–2971CrossRefPubMed

Zurück zum Zitat Srivastava R, Blackstone EH, Lauer MS (2000) Association of smoking with abnormal exercise heart rate responses and long-term prognosis in a healthy, population-based cohort. Am J Med 109:20–26CrossRefPubMed Srivastava R, Blackstone EH, Lauer MS (2000) Association of smoking with abnormal exercise heart rate responses and long-term prognosis in a healthy, population-based cohort. Am J Med 109:20–26CrossRefPubMed

Zurück zum Zitat Azarbal B, Hayes SW, Lewin HC, Hachamovitch R, Cohen I, Berman DS (2004) The incremental prognostic value of percentage of heart rate reserve achieved over myocardial perfusion single-photon emission computed tomography in the prediction of cardiac death and all-cause mortality: superiority over 85% of maximal age-predicted heart rate. J Am Coll Cardiol 44:423–430CrossRefPubMed Azarbal B, Hayes SW, Lewin HC, Hachamovitch R, Cohen I, Berman DS (2004) The incremental prognostic value of percentage of heart rate reserve achieved over myocardial perfusion single-photon emission computed tomography in the prediction of cardiac death and all-cause mortality: superiority over 85% of maximal age-predicted heart rate. J Am Coll Cardiol 44:423–430CrossRefPubMed

Zurück zum Zitat Lábrová R, Honzíková N, Maderová E, Vysocanová P, Nováková Z, Závodná E, Fiser B, Semrad B (2005) Age-dependent relationship between the carotid intima-media thickness, baroreflex sensitivity, and the inter-beat interval in normotensive and hypertensive subjects. Physiol Res 54:593–600PubMed Lábrová R, Honzíková N, Maderová E, Vysocanová P, Nováková Z, Závodná E, Fiser B, Semrad B (2005) Age-dependent relationship between the carotid intima-media thickness, baroreflex sensitivity, and the inter-beat interval in normotensive and hypertensive subjects. Physiol Res 54:593–600PubMed

Zurück zum Zitat Gianaros PJ, Jennings JR, Olafsson GB, Steptoe A, Sutton-Tyrrell K, Muldoon MF, Manuck SB (2002) Greater intima-media thickness in the carotid bulb is associated with reduced baroreflex sensitivity. Am J Hypertens 15:486–491PubMedCentralCrossRefPubMed Gianaros PJ, Jennings JR, Olafsson GB, Steptoe A, Sutton-Tyrrell K, Muldoon MF, Manuck SB (2002) Greater intima-media thickness in the carotid bulb is associated with reduced baroreflex sensitivity. Am J Hypertens 15:486–491PubMedCentralCrossRefPubMed