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Child's Nervous System
Erschienen in: Child's Nervous System 7/2008

01.07.2008 | Review Paper

Radiation-induced brain tumours after central nervous system irradiation in childhood: a review

Erschienen in: Child's Nervous System | Ausgabe 7/2008

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Abstract

Objects

Radiation-induced cerebral tumours constitute a significant risk for subjects undergoing radiotherapy for the management of cerebral neoplasms. Age-related cerebral vulnerability could be a specific factor in the genesis of these complications.

Methods

The pertinent literature of both paediatric and adult series has been reviewed. Three personal cases were added.

Results

One hundred forty-two paediatric second brain tumours were evaluated. Out of them, 69 were malignant gliomas, 33 meningiomas, 8 sarcomatous lesions and 13 low-grade astrocytomas. The average latency period for the appearance of the second tumour was 8 years. Among the second tumours occurring in adults, meningioma is the most common. In this subgroup, the latency period ranged between 16 and 30 years.

Conclusion

Paediatric radiation-induced brain tumours differ from the adult counterpart for both the histological subtypes. These figures indicate a specific vulnerability of the infantile brain demonstrated by the most frequent occurrence of highly malignant lesions.
Literatur
1.
Al-Mefty O, Topsakal C, Pravdenkova S, Sawyer JR, Harrison M (2004) Radiation induced meningiomas; clinical, pathological, cytokinetic, and cytogenetic characteristics. J Neurosurg 100:1002–1013PubMed
2.
Amirjamshidi A, Abbassioun K (2000) Radiation-induced tumors of the central nervous system occurring in childhood and adolescence. Four unusual lesions in three patients and a review of the literature. Childs Nerv Syst 16:390–397PubMedCrossRef
3.
Balasubramaniam C, Armstrong D, Cheek W, Laurent J (1988) Postradiation meningioma in a child. Pediatr Neurosci 14:319–323PubMedCrossRef
4.
Beller AJ, Feinsod M, Sahar A (1972) The possible relationship between small dose irradiation to the scalp and intracranial meningiomas. Neurochirurgia 15:135–143PubMed
5.
Bentzen SM, Atasoy BM, Daley FM (2005) Epidermal growth factor receptor expression in pre-treatment biopsies from head and neck squamous cell carcinoma as a predictive factor for a benefit from accelerated radiation therapy in a randomized controlled trial. J Clin Oncol 24:5560–5567CrossRef
6.
Bliss P, Kerr GR, Gregor A (1994) Incidence of second brain tumours after pituitary irradiation in Edinburgh 1962–1990. Clin Oncol 6:361–363CrossRef
7.
Boljesikova E, Chorvath M, Hurta P, Steno J, Bizik I (2001) Radiation-induced meningioma with a long latency period: a case report. Pediatr Radiol 31:607–609PubMedCrossRef
8.
Broniscer A, Ke W, Fuller CE, Wu J, Gajjar A, Kun LE (2004) Second neoplasms in pediatric patients with primary central nervous system tumors. Cancer 100(10):2246–2252PubMedCrossRef
9.
Caglar K, Varan A, Akyuz C, Selek U, Kutluk T, Yalcin B, Atahan L, Buyukpamukcu M (2006) Second neoplasms in pediatric patients treated for cancer: a center’s 30-year experience. J Pediatr Hematol Oncol 28:374–378PubMedCrossRef
10.
Cahan WG, Woodard HQ, Higinbotham NL, Stewart FW, Coley BL (1948) Sarcoma arising in irradiated bone: report of eleven cases. Cancer 82:8–34CrossRef
11.
Campbell RM, Mader RD, Dufresne RG Jr (2005) Meningiomas after medulloblastoma irradiation treatment in a patient with basal cell nevus syndrome. J Am Acad Dermatol 53(Suppl 1):S256–S259PubMedCrossRef
12.
Cantini R, Giorgetti W, Valleriani AM (1989) Radiation-induced cerebral lesions in childhood. Childs Nerv Syst 5:135–139PubMedCrossRef
13.
Chung CK, Stryker JA, Cruse R (1981) Glioblastoma multiforme following prophylactic cranial irradiation and intrathecal methotrexate in a child with lymphocytic leukaemia. Cancer 47:2563–2566PubMedCrossRef
14.
Cohen MS, Kushner MJ, Dell S (1981) Frontal lobe astrocytoma following radiotherapy for medulloblastoma. Neurology 31:616–619PubMed
15.
De Tommasi A, Occhiogrosso M, De Tommasi C, Cimmino A, Sanguedolce F, Vailati G (2005) Radiation-induced intracranial meningiomas: review of six operated cases. Neurosurg Rev 28:104–114PubMedCrossRef
16.
Dierssen G, Alvarez G, Figols J (1988) Anaplastic astrocytomas associated with previous radiotherapy: report of three cases. Neurosurgery 22(6):1095–1097PubMedCrossRef
17.
Dorfmuller G, Wurtz FG, Kleinert R, Lanner G (1997) Cerebral primitive neuro-ectodermal tumor following treatment of a unilateral retinoblastoma. Acta Neurochir (Wien) 139:749–755CrossRef
18.
Dweik A, Maheut-Lourmiere J, Lioret E, Jan M (1995) Radiation-induced meningioma. Childs Nerv Syst 11:661–663PubMedCrossRef
19.
Furuta T, Sugiu K, Tamiya T, Matsumoto K, Ohmoto T (1998) Malignnt cerebellar astrocytoma developing 15 years after irradiation therapy for a medulloblastoma. Clin Neurol Neurosurg 100:56–59PubMedCrossRef
20.
Ghim TT, Seo JJ, O’Brien M (1993) Childhood intracranial meningioma after high dose irradiation. Cancer 71:4091–4095PubMedCrossRef
21.
Gold DG, Neglia JP, Potish RA (2004) Second neoplasms following megavoltage radiation for pediatric tumors. Cancer 100:212–213PubMedCrossRef
22.
Goldstein AM, Yuen J, Tucker MA (1997) Second cancers after medulloblastoma: population-based results from the United States and Sweden. Cancer Causes Control 8:865–871PubMedCrossRef
23.
Grabb PA, Kelly DR, Fulmer BB, Palmer C (1996) Radiation-induced glioma of the spinal cord. Pediatr Neurosurg 25:214–219PubMedCrossRef
24.
Gutjahr P, Dieterich E (1979) Risk of a second malignant neoplasm after successful treatment of a malignant tumour in children (author’s translation) (article in German). Dtsch Med Wochenschr 104:969–972PubMedCrossRef
25.
Hader WJ, Drovini-Zis K, Maguire JA (2003) Primitive neuroectodermal tumors in the central nervous system following cranial irradiation. Cancer 15:1072–1076CrossRef
26.
Harrison MJ, Wolfe DE, Lau T-S (1991) Radiation induced meningioma: experience at Mount Sinai Hospital and review of the literature. J Neurosurg 75:564–574PubMed
27.
Heyn R, Haeberlen V, Newton WA, Ragab AH, Raney RB, Tefft M, Wharam M, Ensign LG, Maurer HM (1993) Second malignant neoplasms in children treated for rhabdomyosarcoma. J Clin Oncol 11(2):262–270PubMed
28.
Hope AJ, Mansur DB, Tu PH, Simpson JR (2006) Metachronous secondary atypical meningioma and anaplastic astrocytoma after postoperative craniospinal irradiation for medulloblastoma. Childs Nerv Syst 22:1201–1207PubMedCrossRef
29.
Iacono RP, Apuzzo MLJ, Davis RL, Tsai FY (1981) Multiple meningiomas following radiation therapy for medulloblastoma. J Neurosurg 55:282–286PubMed
30.
Ijiri R, Tanaka Y, Hara M, Sekido K (2000) Radiation-associated xanthomatous meningioma in a child. Childs Nerv Syst 16:304–308PubMedCrossRef
31.
Jalali R, Budrukkar A, Sarin R, Sharma DS (2005) High precision conformal radiotherapy employing conservative margins in childhood benign and low-grade brain tumours. Radiother Oncol 74:37–44PubMedCrossRef
32.
Judge MR, Eden OB, O’Neill P (1984) Cerebral glioma after cranial prophylaxis for acute lymphoblastic leukaemia. Br J Med 289:1038–1039
33.
Kantar M, Cetingul N, Konsov S, Anakak Y, Demirtas E, Ersahin Y, Mutluer S (2004) Radiotherapy-induced secondary cranial neoplasms in children. Childs Nerv Syst 20:46–49PubMedCrossRef
34.
Kascten B, Flandroy P, Reznik M, Hainaut H, Stevenaert A (1995) Radiation-induced gliosarcoma: case report and review of the literature. J Neurosurg 83:154–162
35.
Kitanaka C, Shitara N, Nakagomi T, Nakamura H, Genka S, Nakagawa K, Akanuma A, Aoyama H, Takakura K (1989) Postradiation glioma. J Neurosurg 70:469–474PubMedCrossRef
36.
Kleinschmidt-DeMasters BK, Lillehei KO (1995) Radiation-induced meningioma with a 63-year latency period. Case report. J Neurosurg 82(3):487–488PubMed
37.
Kleriga E, Hollenberg Sher J, Nallainathan SK, Stein SC, Sacher M (1978) Development of cerebellar malignant astrocytoma at site of a medulloblastoma treated 11 years earlier. J Neurosurg 49:445–449PubMed
38.
Kranzinger M, Jones N, Rittinger O, Pilz P, Piotrowski WP, Manzi M, Galvan G, Kogelnik HD (2001) Malignant glioma as a secondary malignant neoplasm after radiation therapy for craniopharyngioma: report of a case and review of reported cases. Onkologie 24:66–72PubMedCrossRef
39.
Liwnicz BH, Berger TS, Liwnicz RG, Aron BS (1985) Radiation-associated gliomas: a report of four cases and analysis of postradiation tumors of the central nervous system. Neurosurgery 17:436–445PubMedCrossRef
40.
Loeffler JS, Niemierko A, Chapman PH (2003) Second tumors after radiosurgery: tip of the iceberg or a bump in the road? Neurosurgery 52:1436–1442PubMedCrossRef
41.
Loning L, Zimmermann M, Reiter A, Kaatsch P, Henze G, Riehm H, Schrappe M (2000) Secondary neoplasms subsequent to Berlin-Frankfurt-Munster therapy of acute lymphoblastic leukaemia in childhood: significantly lower risk without cranial radiotherapy. Blood 95:2770–2775PubMed
42.
Maat-Schieman MLC, Bots GTAM, Thomeer RTWM, Vielvoye GJ (1985) Malignant astrocytoma following radiotherapy for craniopharyngioma. Br J Radiol 58:480–482PubMed
43.
Mack EE, Wilson CB (1993) Meningiomas induced by high-dose cranial irradiation. J Neurosurg 79:28–31PubMed
44.
Malde R, Jalali R, Muzumdar D, Shet T, Kurkure P (2004) Gliosarcoma occurring 8 years after treatment for a medulloblastoma. Childs Nerv Syst 20:243–246PubMedCrossRef
45.
Mann I, Yates PC, Ainslie JP (1953) Unusual case of double primary orbital tumour. Br J Ophthalmol 37:758–762PubMedCrossRef
46.
Martinez-Lage J, de San Pedro JR, Martinez-Perez M, Poza M (2005) Meningiomas after radiation-therapy for benign astrocytomas. Neurocirugia 16:266–270PubMed
47.
Marus G, Levin CV, Rutherfoord GS (1986) Malignant glioma following radiotherapy for unrelated primary tumors. Cancer 58:886–894PubMedCrossRef
48.
McWhirter WR, Pearn JH, Smith H, O’Regan P (1986) Cerebral astrocytoma as a complication of acute lymphoblastic leukaemia. Med J Aust 145:96–97PubMed
49.
Menon G, Nair S, Rajesh BJ, Rao BR, Radhakrishan VV (2007) Malignant astrocytoma following radiotherapy for craniopharyngioma. J Cancer Res Ther 3:50–52PubMedCrossRef
50.
Merchant TE, Kiehna EN, Li C, Shukla H, Sengupta S, Xiong X, Gajjar A, Mulhern RK (2006) Modeling radiation dosimetry to predict cognitive outcomes in pediatric patients with CNS embryonal tumors including medulloblastoma. Int J Radiat Oncol Biol Phys 65:210–221PubMed
51.
Minniti G, Traish D, Ashley S, Gonsalves A, Brada M (2005) Risk of second brain tumor after conservative surgery and radiotherapy for pituitary adenoma: update after an additional 10 years. J Clin Endocrinol Metab 90:800–804PubMedCrossRef
52.
Moss SD, Rockswold GL, Chou SN, Yock D, Berger MS (1988) Radiation-induced meningiomas in pediatric patients. Neurosurgery 22:758–761PubMedCrossRef
53.
Musa BS, Pople IK, Cummins BH (1995) Intracranial meningiomas following irradiation—a growing problem? Br J Neurosurg 9:629–637PubMedCrossRef
54.
Muzumdar DP, Desai K, Goel A (1999) Glioblastoma multiforme following prophylactic cranial irradiation and intrathecal methotrexate in a child with acute lymphoblastic leukaemia: a case report. Neurol India 47(2):142–144PubMed
55.
Nakamizo A, Nishio S, Inamura T, Koga H, Yamabe K, Kuba H, Matsushima T, Fikui M (2001) Evolution of malignant cerebellar astrocytoma at the site of a treated medulloblastoma: report of two cases. Acta Neurochir (Wien) 143:697–700CrossRef
56.
Neglia JP, Friedman DL, Yasui Y, Mertens AC, Hammond S, Stovall M, Donaldson SS, Meadows AT, Robison LL (2001) Second malignant neoplasms in five-year survivors of childhood cancer: childhood cancer survivor study. J Nat Canc Inst 93:618–629CrossRef
57.
Nishio S, Morioka T, Inamura T, Takeshita I, Fukui M, Sasaki M, Nakamura K, Wakisaka S (1998) Radiation-induced brain tumours: potential late complications of radiation therapy for brain tumours. Acta Neurochir (Wien) 140:763–770CrossRef
58.
Norwood CW, Relly DL, Davis C Jr (1974) Irradiation induced mesodermal tumors of the central nervous system: report of two meningiomas following X-ray treatment for gliomas. Surg Neurol 2:161–164PubMed
59.
Ojeda VJ, Stokes BA, Woodland P (1987) Meningioma occurring twenty-three years after a successfully treated cerebellar medulloblastoma: case report. Aust N Z J Surg 57(2):133–135PubMedCrossRef
60.
O’Malley S, Weitman D, Olding M, Sekhar L (1997) Multiple neoplasms following craniospinal irradiation for medulloblastoma in a patient with nevoid basal cell carcinoma syndrome. J Neurosurg 86:286–288PubMed
61.
Osumi AK, Mclendon RE, Tien RD, Friedman HS, Graham M, Hockenberger B, Halperin EC, Oakes WJ (1994) Well differentiated astrocytoma occurring nine years after radiation therapy for medulloblastoma. Clin Neuropathol 13:281–285PubMed
62.
Palma L, Vagnozzi R, Annino L, Ciapetta P, Maleci A, Cantore G (1988) Post-radiation glioma in a child. Childs Nerv Syst 4:296–301PubMed
63.
Pearl GS, Mirra SS, Miles ML (1980) Glioblastoma occurring 13 years after treatment of a medulloblastoma. Neurosurgery 6(5):546–551PubMedCrossRef
64.
Prasad ML, Mahapatra AK, Dinda AK, Sarkar C, Roy S (1991) Fibrosarcoma of the scalp following postoperative radiotherapy for medulloblastoma. Acta Neurochir (Wien) 109:145–149CrossRef
65.
Raffel C, Edwards MS, Davis RL, Ablin AR (1985) Postirradiation cerebellar glioma. Case report. J Neurosurgery 62:300–303
66.
Rappaport ZH, Loven D, Ben-Aharon U (1991) Radiation-induced cerebellar glioblastoma multiforme subsequent to treatment of an astrocytoma of the cervical spinal cord. Neurosurgery 29:606–608PubMedCrossRef
67.
Relling MV, Rubnitz JE, Rivera GK, Boyett JM, Hancock ML, Felix CA, Kun LE, Walter AW, Evans WE, Pui CH (1999) High incidence of secondary brain tumors after radiotherapy and antimetabolites. Lancet 354:34–39PubMedCrossRef
68.
Rittinger M, Jones N, Rittinger O, Pilz P, Piotrowski WP, Manzl M, Galvan G, Kogelnik HD (2001) Malignant glioma as a secondary malignant neoplasms after radiation therapy for craniopharyngioma: report of a case and review of reported cases. Onkologie 24:66–72PubMedCrossRef
69.
Robinson RG (1978) A second brain tumour and irradiation. J Neurol Neurosurg Psych 41:1005–1012
70.
Romeike BFM, Kim YJ, Steudel WI, Graf N (2007) Diffuse high-grade gliomas as second malignant neoplasms after radio-chemotherapy for pediatric malignancies. Childs Nerv Syst 23:185–193PubMedCrossRef
71.
Rubinstein AB, Shalit MN, Cohen ML (1984) Radiation-induced cerebral meningioma: a recognizable entity. J Neurosurg 61:966–971PubMed
72.
Safneck JR, Napier LB, Halliday WC (1992) Malignant astrocytoma of the optic nerve in a child. Can J Neurol Sci 19:498–503PubMed
73.
Salvati M, Cervoni L, Puzzilli F (1997) High-dose radiation-induced meningiomas. Surg Neurol 47:435–442PubMedCrossRef
74.
Salvati M, Frati A, Russo N, Caroli E, Polli FM, Minniti G, Delfini R (2003) Radiation-induced gliomas: report of 10 cases and review of the literature. Surg Neurol 60:60–67PubMedCrossRef
75.
Sasaki M, Ichiya Y, Kuwabara Y, Yoshida T, Inoue T, Morioka T, Hisada K, Fukui M, Masuda K (1996) Hyperperfusion and hypermetabolism in brain radiation necrosis with epileptic activity. J Nucl Med 37:1174–1176PubMed
76.
Schmidbauer M, Budka H, Bruckner R, Vorkapic P (1987) Glioblastoma developing at the site of a cerebellar medulloblastoma treated 6 years earlier. Case report. J Neurosurg 67:915–918PubMedCrossRef
77.
Shintani T, Hayakawan H, Hoshi M, Sumida M, Kurisu K, Oki S, Kodama Y, Kajiakawa H, Inai K, Kamada N (1999) High incidence of meningioma among Hiroshima atomic bomb survivors. J Radiat Res 40:49–57PubMedCrossRef
78.
Simmons NE, Laws ER (1998) Glioma occurrence after sellar irradiation: case report and review. Neurosurgery 42(1):172–178PubMedCrossRef
79.
Soffer D, Pittaluga S, Feiner M, Beller A (1983) Intracranial meningiomas following low-dose irradiation to the head. J Neurosurg 59:1048–1053PubMed
80.
Sogg RL, Donaldson SS, Yorke CH (1978) Malignant astrocytoma following radiotherapy of a craniopharyngioma. Case report. J Neurosurg 48:622–627PubMed
81.
Strojan P, Popovic M, Jereb B (2000) Secondary intracranial meningiomas after high-dose cranial irradiation: report of five cases and review of the literature. Int J Radiat Oncol Biol Phys 48:65–73PubMedCrossRef
82.
Tada M, Sawamura Y, Abe H, Iggo R (1997) Homozygous p53 gene mutation in a radiation-induced glioblastoma 10 years after treatment for an intracranial germ cell tumor: case report. Neurosurgery 40:393–396PubMedCrossRef
83.
Tashima T, Morioka T, Nishio S, Hascisuga S, Fukui M, Sasaki M (1998) Delayed cerebral radiation necrosis with a high uptake of 11C-methionine on PET and 201Tl-chrolide on SPECT studies. Neuroradiology 40(7):435–438PubMedCrossRef
84.
Terry RD (1959) Combined nonmetastasizing fibrosarcoma and chromophobe tumour of pituitary. Cancer 12:791–798PubMedCrossRef
85.
Tsang RW, Laperriere NJ, Simpson WJ, Brierley J, Panzarella T, Smyth HS (1993) Glioma arising after radiation therapy for pituitary adenoma. A report of four patients and estimation of risk. Cancer 72:2227–2233PubMedCrossRef
86.
Valerie K, Yacoub A, Hagan MP, Curiel DT, Fisher PB, Grant S, Dent P (2007) Radiation-induced cell signalling: inside-out and outside-in. Mol Cancer Ther 6(3):789–801PubMedCrossRef
87.
Waja S, Handa H (1976) Radiation-induced meningiomas: with review of literature. Surg Neurol 5:215–219
88.
Ware ML, Cha S, Gupta N, Perry VL (2004) Radiation-induced atypical meningioma with rapid growth in a 13-year-old girl. J Neurosurg (Pediatrics 5) 100:488–491
89.
Willers H, Held KD (2006) Introduction to clinical radiation biology. Hematol Oncol Clin North Am 1:1–24CrossRef
90.
Wilson CB (1994) Meningiomas: genetics, malignancy, and the role of radiation in induction and treatment. J Neurosurg 81:666–675PubMed
91.
Wong TT, Chen YW, Guo WY, Kai-Ping C, Donald MH, Sang-Hue Y (2008) Germinoma involving the basal ganglion in children. Childs Nerv Syst 24:71–78PubMedCrossRef
92.
Ushio Y, Arita N, Yoshimine T, Nagatani M, Mogami H (1987) Glioblastoma after radiotherapy for craniopharyngioma: case report. Neurosurgery 21:33–38PubMedCrossRef
93.
Yang SY, Wang KC, Cho BK, Kim YY, Lim SY, Park SH, Kim IH, Kim SKK (2005) Radiation-induced cerebellar glioblastoma at the site of a treated medulloblastoma. J Neurosurg (Pediatrics 4) 102:417–422
Metadaten
Titel
Radiation-induced brain tumours after central nervous system irradiation in childhood: a review
Publikationsdatum
01.07.2008
Erschienen in
Child's Nervous System / Ausgabe 7/2008
Print ISSN: 0256-7040
Elektronische ISSN: 1433-0350
DOI
https://doi.org/10.1007/s00381-008-0631-7

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