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Pediatric Surgery International

Erschienen in:

01.09.2015 | Review Article

Anorectal malformation: the etiological factors

verfasst von: Chen Wang, Long Li, Wei Cheng

Erschienen in: Pediatric Surgery International | Ausgabe 9/2015

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Abstract

Anorectal malformation (ARM) is a congenital anomaly commonly encountered in pediatric surgery practice. Although surgical procedures correct the anatomical anomalies, the post-operative bowel function is not universally satisfactory. The etiology of ARM remains unclear. In this review, we summarize the current understanding of the genetic and epigenetic factors contributing to the pathogenesis of ARM, based on published animal models, human genetics and epidemiological researches. Appreciation of these factors may be helpful in the management of ARM in the future.

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Titel: Anorectal malformation: the etiological factors
verfasst von: Chen Wang
Long Li
Wei Cheng
Publikationsdatum: 01.09.2015
Verlag: Springer Berlin Heidelberg
Erschienen in: Pediatric Surgery International / Ausgabe 9/2015
Print ISSN: 0179-0358
Elektronische ISSN: 1437-9813
DOI: https://doi.org/10.1007/s00383-015-3685-0

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