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Erschienen in: Pediatric Surgery International 12/2018

06.10.2018 | Original Article

The non-visualized appendix and secondary signs on ultrasound for pediatric appendicitis in the community hospital setting

verfasst von: Jenny M. Held, Christian S. McEvoy, Jonathan D. Auten, Stephen L. Foster, Robert L. Ricca

Erschienen in: Pediatric Surgery International | Ausgabe 12/2018

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Abstract

Background

Secondary signs of appendicitis on ultrasound may aid with diagnosis in the setting of a non-visualized appendix (NVA). This role has not been shown in the community hospital setting.

Materials and methods

All right lower quadrant ultrasounds performed in children for clinical suspicion of appendicitis over a 5-year period in a single community hospital were evaluated. Secondary signs of inflammation including free fluid, ileus, fat stranding, abscess, and lymphadenopathy were documented. Patients were followed for 1 year for the primary outcome of appendicitis. These data were analyzed to determine the utility of secondary signs in the diagnosis of acute appendicitis when an NVA is reported.

Results

Six hundred and seventeen ultrasounds were reviewed; 470 of these had an NVA. Of NVAs, 47 (10%) of patients were diagnosed with appendicitis. Sensitivity and specificity of having at least one secondary were 38.3% and 80%, respectively. The positive and negative predictive values of having at least one secondary sign were 17.3% and 92%, respectively.

Conclusion

These data suggest that the absence of secondary signs has a strong negative predictive value for appendicitis in the community hospital setting; however, the full utility of secondary signs may be limited in this setting.
Literatur
1.
Zurück zum Zitat Doria AS, Moineddin R, Kellenberger CJ et al (2006) US or CT for diagnosis of appendicitis in children and adults? A meta-analysis. Radiology 241(1):83–94CrossRef Doria AS, Moineddin R, Kellenberger CJ et al (2006) US or CT for diagnosis of appendicitis in children and adults? A meta-analysis. Radiology 241(1):83–94CrossRef
2.
Zurück zum Zitat Scholer SJ, Pituch K, Orr DP, Dittus RS (1996) Clinical outcomes of children with acute abdominal pain. Pediatrics 98(4 Pt 1):680–685PubMed Scholer SJ, Pituch K, Orr DP, Dittus RS (1996) Clinical outcomes of children with acute abdominal pain. Pediatrics 98(4 Pt 1):680–685PubMed
3.
Zurück zum Zitat Mostbeck G, Adam EJ, Nielsen MB et al (2016) How to diagnose acute appendicitis: ultrasound first. Insights Imaging 7(2):255–263CrossRef Mostbeck G, Adam EJ, Nielsen MB et al (2016) How to diagnose acute appendicitis: ultrasound first. Insights Imaging 7(2):255–263CrossRef
4.
Zurück zum Zitat Al-Khayal KA, Al-Omran MA (2007) Computed tomography and ultrasonography in the diagnosis of equivocal acute appendicitis. A meta-analysis. Saudi Med J 28(2):173–180PubMed Al-Khayal KA, Al-Omran MA (2007) Computed tomography and ultrasonography in the diagnosis of equivocal acute appendicitis. A meta-analysis. Saudi Med J 28(2):173–180PubMed
5.
Zurück zum Zitat Puylaert JB (1986) Acute appendicitis: US evaluation using graded compression. Radiology 158(2):355–360CrossRef Puylaert JB (1986) Acute appendicitis: US evaluation using graded compression. Radiology 158(2):355–360CrossRef
6.
Zurück zum Zitat Estey A, Poonai N, Lim R (2013) Appendix not seen: the predictive value of secondary inflammatory sonographic signs. Pediatr Emerg Care 29(4):435–439CrossRef Estey A, Poonai N, Lim R (2013) Appendix not seen: the predictive value of secondary inflammatory sonographic signs. Pediatr Emerg Care 29(4):435–439CrossRef
7.
Zurück zum Zitat Jaremko JL, Crockett A, Rucker D, Magnus KG (2011) Incidence and significance of inconclusive results in ultrasound for appendicitis in children and teenagers. Can Assoc Radiol J 62(3):197–202CrossRef Jaremko JL, Crockett A, Rucker D, Magnus KG (2011) Incidence and significance of inconclusive results in ultrasound for appendicitis in children and teenagers. Can Assoc Radiol J 62(3):197–202CrossRef
8.
Zurück zum Zitat Kearl YL, Claudius I, Behar S et al (2016) Accuracy of magnetic resonance imaging and ultrasound for appendicitis in diagnostic and non-diagnostic studies. Acad Emerg Med 23(2):179–185CrossRef Kearl YL, Claudius I, Behar S et al (2016) Accuracy of magnetic resonance imaging and ultrasound for appendicitis in diagnostic and non-diagnostic studies. Acad Emerg Med 23(2):179–185CrossRef
9.
Zurück zum Zitat Keller C, Wang NE, Imler DL, Vasanawala SS, Bruzoni M, Quinn JV (2017) Predictors of nondiagnostic ultrasound for appendicitis. J Emerg Med 52(3):318–323CrossRef Keller C, Wang NE, Imler DL, Vasanawala SS, Bruzoni M, Quinn JV (2017) Predictors of nondiagnostic ultrasound for appendicitis. J Emerg Med 52(3):318–323CrossRef
10.
Zurück zum Zitat Nah SA, Ong SS, Lim WX, Amuddhu SK, Tang PH, Low Y (2017) Clinical relevance of the nonvisualized appendix on ultrasonography of the abdomen in children. BioMed Res Int 182:164–169.e161 Nah SA, Ong SS, Lim WX, Amuddhu SK, Tang PH, Low Y (2017) Clinical relevance of the nonvisualized appendix on ultrasonography of the abdomen in children. BioMed Res Int 182:164–169.e161
11.
Zurück zum Zitat Ross MJ, Liu H, Netherton SJ et al (2014) Outcomes of children with suspected appendicitis and incompletely visualized appendix on ultrasound. Acad Emerg Med 21(5):538–542CrossRef Ross MJ, Liu H, Netherton SJ et al (2014) Outcomes of children with suspected appendicitis and incompletely visualized appendix on ultrasound. Acad Emerg Med 21(5):538–542CrossRef
12.
Zurück zum Zitat Crady SK, Jones JS, Wyn T, Luttenton CR (1993) Clinical validity of ultrasound in children with suspected appendicitis. Ann Emerg Med 22(7):1125–1129CrossRef Crady SK, Jones JS, Wyn T, Luttenton CR (1993) Clinical validity of ultrasound in children with suspected appendicitis. Ann Emerg Med 22(7):1125–1129CrossRef
13.
Zurück zum Zitat Wiersma FTB, Bloem JL, Allema JH, Holscher HC (2009) US examination of the appendix in children with suspected appendicitis: the additional value of secondary signs. Eur Radiol 19(2):455–461CrossRef Wiersma FTB, Bloem JL, Allema JH, Holscher HC (2009) US examination of the appendix in children with suspected appendicitis: the additional value of secondary signs. Eur Radiol 19(2):455–461CrossRef
14.
Zurück zum Zitat Cohen B, Bowling J, Midulla P et al (2015) The non-diagnostic ultrasound in appendicitis: is a non-visualized appendix the same as a negative study? J Pediatr Surg 50(6):923–927CrossRef Cohen B, Bowling J, Midulla P et al (2015) The non-diagnostic ultrasound in appendicitis: is a non-visualized appendix the same as a negative study? J Pediatr Surg 50(6):923–927CrossRef
15.
Zurück zum Zitat Shah BR, Stewart J, Jeffrey RB, Olcott EW (2014) Value of short-interval computed tomography when sonography fails to visualize the appendix and shows otherwise normal findings. J Ultrasound Med 33(9):1589–1595CrossRef Shah BR, Stewart J, Jeffrey RB, Olcott EW (2014) Value of short-interval computed tomography when sonography fails to visualize the appendix and shows otherwise normal findings. J Ultrasound Med 33(9):1589–1595CrossRef
16.
Zurück zum Zitat Srinivasan A, Servaes S, Pena A, Darge K (2015) Utility of CT after sonography for suspected appendicitis in children: integration of a clinical scoring system with a staged imaging protocol. Emerg Radiol 22(1):31–42CrossRef Srinivasan A, Servaes S, Pena A, Darge K (2015) Utility of CT after sonography for suspected appendicitis in children: integration of a clinical scoring system with a staged imaging protocol. Emerg Radiol 22(1):31–42CrossRef
17.
Zurück zum Zitat Alter SM, Walsh B, Lenehan PJ, Shih RD (2017) Ultrasound for diagnosis of appendicitis in a community hospital emergency department has a high rate of non-diagnostic studies. J Emerg Med 52(6):833–838CrossRef Alter SM, Walsh B, Lenehan PJ, Shih RD (2017) Ultrasound for diagnosis of appendicitis in a community hospital emergency department has a high rate of non-diagnostic studies. J Emerg Med 52(6):833–838CrossRef
18.
Zurück zum Zitat Larson DB, Trout AT, Fierke SR, Towbin AJ (2015) Improvement in diagnostic accuracy of ultrasound of the pediatric appendix through the use of equivocal interpretive categories. AJR Am J Roentgenol 204(4):849–856CrossRef Larson DB, Trout AT, Fierke SR, Towbin AJ (2015) Improvement in diagnostic accuracy of ultrasound of the pediatric appendix through the use of equivocal interpretive categories. AJR Am J Roentgenol 204(4):849–856CrossRef
19.
Zurück zum Zitat Anandalwar SP, Callahan MJ, Bachur RG et al (2015) Use of white blood cell count and polymorphonuclear leukocyte differential to improve the predictive value of ultrasound for suspected appendicitis in children. J Am Coll Surg 220(6):1010–1017CrossRef Anandalwar SP, Callahan MJ, Bachur RG et al (2015) Use of white blood cell count and polymorphonuclear leukocyte differential to improve the predictive value of ultrasound for suspected appendicitis in children. J Am Coll Surg 220(6):1010–1017CrossRef
20.
Zurück zum Zitat Pastore V, Cocomazzi R, Basile A, Pastore M, Bartoli F (2014) Limits and advantages of abdominal ultrasonography in children with acute appendicitis syndrome. Afr J Paediatr Surg 11(4):293–296CrossRef Pastore V, Cocomazzi R, Basile A, Pastore M, Bartoli F (2014) Limits and advantages of abdominal ultrasonography in children with acute appendicitis syndrome. Afr J Paediatr Surg 11(4):293–296CrossRef
21.
Zurück zum Zitat Fallon SC, Orth RC, Guillerman RP et al (2015) Development and validation of an ultrasound scoring system for children with suspected acute appendicitis. Pediatr Radiol 45(13):1945–1952CrossRef Fallon SC, Orth RC, Guillerman RP et al (2015) Development and validation of an ultrasound scoring system for children with suspected acute appendicitis. Pediatr Radiol 45(13):1945–1952CrossRef
Metadaten
Titel
The non-visualized appendix and secondary signs on ultrasound for pediatric appendicitis in the community hospital setting
verfasst von
Jenny M. Held
Christian S. McEvoy
Jonathan D. Auten
Stephen L. Foster
Robert L. Ricca
Publikationsdatum
06.10.2018
Verlag
Springer Berlin Heidelberg
Erschienen in
Pediatric Surgery International / Ausgabe 12/2018
Print ISSN: 0179-0358
Elektronische ISSN: 1437-9813
DOI
https://doi.org/10.1007/s00383-018-4350-1

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