Skip to main content
Erschienen in: International Journal of Colorectal Disease 12/2009

01.12.2009 | Original Article

Predicting post-operative mortality in patients undergoing colorectal surgery using P-POSSUM and CR-POSSUM scores: a prospective study

verfasst von: Edmund Leung, Ali M. Ferjani, Nigel Stellard, Ling S. Wong

Erschienen in: International Journal of Colorectal Disease | Ausgabe 12/2009

Einloggen, um Zugang zu erhalten

Abstract

Introduction

POSSUM and its variants Portsmouth POSSUM (P-POSSUM) and Colorectal POSSUM (CR-POSSUM) equations were derived from a heterogeneous general surgical population, which have been used successfully to provide risk-adjusted operative mortality rates. CR-POSSUM utilises fewer parameters, allowing ease of use. The aim of this study was to predict the mortality outcome in colorectal surgery using these scoring systems compared to the observed mortality and to devise a new scoring system with improved accuracy.

Methods

The study was conducted prospectively on all consecutive patients requiring elective and emergency colorectal surgery between April 2002 and May 2005. The outcome parameter was defined as 30-day mortality. The observed mortality was compared with predicted mortality by the scoring systems. Hosmer and Lemeshow test was used to assess statistical accuracy of POSSUM.

Results

Eight hundred ninety-nine patients underwent colorectal surgery during the study period. There were 619 elective and 281 emergency patients. Observed 30-day mortality rate was 9%, compared with predicted mortality rate of 13.5% with POSSUM, 5% with P-POSSUM and 9.5% with CR-POSSUM.

Conclusion

POSSUM’s mortality rate was overestimated, while P-POSSUM’s mortality rate was underestimated. CR-POSSUM, the simplest system of all three, most accurately predicted mortality in our unit.
Literatur
1.
Zurück zum Zitat Coleman MP, Rachet B, Woods LM, Mitry E, Riga M, Cooper N, Quinn MJ, Brenner H, Esteve J (2004) Trends and socioeconomic inequalities in cancer survival in England and Wales up to 2001. Br J Cancer 90(7):1367–1373CrossRefPubMed Coleman MP, Rachet B, Woods LM, Mitry E, Riga M, Cooper N, Quinn MJ, Brenner H, Esteve J (2004) Trends and socioeconomic inequalities in cancer survival in England and Wales up to 2001. Br J Cancer 90(7):1367–1373CrossRefPubMed
2.
Zurück zum Zitat McArdle CS, Hole DJ (2002) Outcome following surgery for colorectal cancer: analysis by hospital after adjustment for case-mix and deprivation. Br J Cancer 86(3):331–335CrossRefPubMed McArdle CS, Hole DJ (2002) Outcome following surgery for colorectal cancer: analysis by hospital after adjustment for case-mix and deprivation. Br J Cancer 86(3):331–335CrossRefPubMed
3.
4.
Zurück zum Zitat Copeland GP, Jones D, Walters M (1991) POSSUM: a scoring system of surgical audit. Br J Surg 78:355–360CrossRefPubMed Copeland GP, Jones D, Walters M (1991) POSSUM: a scoring system of surgical audit. Br J Surg 78:355–360CrossRefPubMed
5.
Zurück zum Zitat Prytherch DR, Whiteley MS, Higgins B, Weaver PC, Prout WG, Powell SJ (1998) POSSUM and portsmouth POSSUM for predicting mortality. Physiological and operative severity score for the enumeration of mortality and morbidity. Br J Surg 85(9):1217–1220CrossRefPubMed Prytherch DR, Whiteley MS, Higgins B, Weaver PC, Prout WG, Powell SJ (1998) POSSUM and portsmouth POSSUM for predicting mortality. Physiological and operative severity score for the enumeration of mortality and morbidity. Br J Surg 85(9):1217–1220CrossRefPubMed
6.
Zurück zum Zitat Menon KV, Farouk R (2002) An analysis of the accuracy of P-POSSUM scoring for mortality risk assessment after surgery for colorectal cancer. Colorectal Dis 4:197–200CrossRefPubMed Menon KV, Farouk R (2002) An analysis of the accuracy of P-POSSUM scoring for mortality risk assessment after surgery for colorectal cancer. Colorectal Dis 4:197–200CrossRefPubMed
7.
Zurück zum Zitat Tekkis PP, Prytherch DR, Kocher HM, Senapati A, Poloniecki J, Stamataki D, Windsor ACJ (2004) Development of dedicated risk-adjusted scoring system for colorectal surgery (colorectal POSSUM). Br J Surg 91:1174–1182CrossRefPubMed Tekkis PP, Prytherch DR, Kocher HM, Senapati A, Poloniecki J, Stamataki D, Windsor ACJ (2004) Development of dedicated risk-adjusted scoring system for colorectal surgery (colorectal POSSUM). Br J Surg 91:1174–1182CrossRefPubMed
8.
Zurück zum Zitat Lemeshow S, Hosmer DW (1982) A review of goodness of fit statistics for use in the development of logistic regression models. Am J Epidemiol 115:92–106PubMed Lemeshow S, Hosmer DW (1982) A review of goodness of fit statistics for use in the development of logistic regression models. Am J Epidemiol 115:92–106PubMed
9.
Zurück zum Zitat Zafirellis KD, Fountoulakis A, Dolan K, Dexter SPL, Martin IG, Sue-Ling HM (2002) Evaluation of POSSUM in patients with oesophageal cancer. Br J Surg 89:1150–1155CrossRefPubMed Zafirellis KD, Fountoulakis A, Dolan K, Dexter SPL, Martin IG, Sue-Ling HM (2002) Evaluation of POSSUM in patients with oesophageal cancer. Br J Surg 89:1150–1155CrossRefPubMed
10.
Zurück zum Zitat Fazio VW, Tekkis PP, Remzi F, Lavery IC (2004) Assessment of operative risk in colorectal cancer surgery: the Cleveland Clinic Foundation colorectal cancer model. Dis Colon Rectum 47(12):2015–2024CrossRefPubMed Fazio VW, Tekkis PP, Remzi F, Lavery IC (2004) Assessment of operative risk in colorectal cancer surgery: the Cleveland Clinic Foundation colorectal cancer model. Dis Colon Rectum 47(12):2015–2024CrossRefPubMed
11.
Zurück zum Zitat Mohil RS, Bhatnagar D, Bahadur L, Rajneesh DDK, Magan M (2004) POSSUM and P-POSSUM for risk adjusted audit of patients undergoing emergency laparotomy. Br J Surg 91:500–503CrossRefPubMed Mohil RS, Bhatnagar D, Bahadur L, Rajneesh DDK, Magan M (2004) POSSUM and P-POSSUM for risk adjusted audit of patients undergoing emergency laparotomy. Br J Surg 91:500–503CrossRefPubMed
12.
Zurück zum Zitat Tekkis PP, Poloniecki JD, Thompson MR, Stamatakis JD (2003) Operative mortality in colorectal cancer: prospective national study. BMJ 327(7425):1196–1201CrossRefPubMed Tekkis PP, Poloniecki JD, Thompson MR, Stamatakis JD (2003) Operative mortality in colorectal cancer: prospective national study. BMJ 327(7425):1196–1201CrossRefPubMed
13.
Zurück zum Zitat Brooks MJ, Sutton R, Sarin S (2005) Comparison of surgical risk score, POSSUM and P-POSSUM in higher-risk surgical patients. Br J Surg 92(10):1288–1292CrossRefPubMed Brooks MJ, Sutton R, Sarin S (2005) Comparison of surgical risk score, POSSUM and P-POSSUM in higher-risk surgical patients. Br J Surg 92(10):1288–1292CrossRefPubMed
14.
Zurück zum Zitat Vather R, Zargar-Shoshtari K, Adegbola S, Hill AG (2006) Comparison of the POSSUM, P-POSSUM and CR-POSSUM scoring systems as predictors of postoperative mortality in patients undergoing major colorectal surgery. ANZ J Surg 76(9):812–816CrossRefPubMed Vather R, Zargar-Shoshtari K, Adegbola S, Hill AG (2006) Comparison of the POSSUM, P-POSSUM and CR-POSSUM scoring systems as predictors of postoperative mortality in patients undergoing major colorectal surgery. ANZ J Surg 76(9):812–816CrossRefPubMed
15.
Zurück zum Zitat Machado F, Barberousse C, Santiago P, Barrios E, Carriquiry L (2007) Comparison of surgical outcomes in two populations with risk adjustment using the POSSUM system. Cir Esp 81(1):31–37CrossRefPubMed Machado F, Barberousse C, Santiago P, Barrios E, Carriquiry L (2007) Comparison of surgical outcomes in two populations with risk adjustment using the POSSUM system. Cir Esp 81(1):31–37CrossRefPubMed
16.
Zurück zum Zitat Ugolini G, Rosati G, Montroni I, Zanotti S, Manaresi A, Giampaolo L, Taffurelli M, Pricolo V (2009) An easy-to-use solution for clinical audit in colorectal cancer surgery. Surgery 145(1):86–92CrossRefPubMed Ugolini G, Rosati G, Montroni I, Zanotti S, Manaresi A, Giampaolo L, Taffurelli M, Pricolo V (2009) An easy-to-use solution for clinical audit in colorectal cancer surgery. Surgery 145(1):86–92CrossRefPubMed
17.
Zurück zum Zitat Ugolini G, Rosati G, Montroni I, Zanotti S, Alessio M, Giampaolo L, Blume JF, Taffurelli M (2008) Can elderly patients with colorectal cancer tolerate planned surgical treatment? A practical approach to a common dilemma. Colorectal Dis, in press Ugolini G, Rosati G, Montroni I, Zanotti S, Alessio M, Giampaolo L, Blume JF, Taffurelli M (2008) Can elderly patients with colorectal cancer tolerate planned surgical treatment? A practical approach to a common dilemma. Colorectal Dis, in press
18.
Zurück zum Zitat Prytherch DR, Ridler BM, Beard JD, Earnshaw JJ (2001) A model for national outcome audit in vascular surgery. Eur J Vasc Endovasc Surg 21:477–483CrossRefPubMed Prytherch DR, Ridler BM, Beard JD, Earnshaw JJ (2001) A model for national outcome audit in vascular surgery. Eur J Vasc Endovasc Surg 21:477–483CrossRefPubMed
19.
Zurück zum Zitat Tekkis PP, McCulloch P, Poloniecki JD, Prytherch DR, Kessaris N, Steger AC (2004) Risk-adjusted prediction of operative mortality in oesophagogastric surgery with O-POSSUM. Br J Surg 91:288–295CrossRefPubMed Tekkis PP, McCulloch P, Poloniecki JD, Prytherch DR, Kessaris N, Steger AC (2004) Risk-adjusted prediction of operative mortality in oesophagogastric surgery with O-POSSUM. Br J Surg 91:288–295CrossRefPubMed
20.
Zurück zum Zitat Senagore AJ, Warmuth AJ, Delaney CP, Tekkis PP, Fazio VW (2004) POSSUM, p-POSSUM, and Cr-POSSUM: implementation issues in a United States health care system for prediction of outcome for colon cancer resection. Dis Colon Rectum 47:1435–1441CrossRefPubMed Senagore AJ, Warmuth AJ, Delaney CP, Tekkis PP, Fazio VW (2004) POSSUM, p-POSSUM, and Cr-POSSUM: implementation issues in a United States health care system for prediction of outcome for colon cancer resection. Dis Colon Rectum 47:1435–1441CrossRefPubMed
21.
Zurück zum Zitat Law WL, Lam CM, Lee YM (2006) Evaluation of outcome of laparoscopic colorectal resection with POSSUM, P-OSSUM and CR-POSSUM. Br J Surg 93:94–99CrossRefPubMed Law WL, Lam CM, Lee YM (2006) Evaluation of outcome of laparoscopic colorectal resection with POSSUM, P-OSSUM and CR-POSSUM. Br J Surg 93:94–99CrossRefPubMed
22.
Zurück zum Zitat Oomen JL, Cuesta MA, Engel AF (2007) Comparison of outcome of POSSUM, p-POSSUM, and cr-POSSUM scoring after elective resection of the sigmoid colon for carcinoma or complicated diverticular disease. Scand J Gastroenterol 42(7):841–847CrossRefPubMed Oomen JL, Cuesta MA, Engel AF (2007) Comparison of outcome of POSSUM, p-POSSUM, and cr-POSSUM scoring after elective resection of the sigmoid colon for carcinoma or complicated diverticular disease. Scand J Gastroenterol 42(7):841–847CrossRefPubMed
23.
Zurück zum Zitat Ren L, Upadhyay AM, Wang L, Li L, Lu J, Fu W (2009) Mortality rate prediction by Physiological and Operative Severity Score for the Enumeration of Mortality and Morbidity (POSSUM), Portsmouth, POSSUM and Colorectal POSSUM and the development of new scoring systems in Chinese colorectal cancer patients. Am J Surg 198(1):31–38CrossRefPubMed Ren L, Upadhyay AM, Wang L, Li L, Lu J, Fu W (2009) Mortality rate prediction by Physiological and Operative Severity Score for the Enumeration of Mortality and Morbidity (POSSUM), Portsmouth, POSSUM and Colorectal POSSUM and the development of new scoring systems in Chinese colorectal cancer patients. Am J Surg 198(1):31–38CrossRefPubMed
24.
Zurück zum Zitat Senagore AJ, Delaney CP, Duepree HJ, Brady KM, Fazio VW (2003) Evaluation of POSSUM and P-POSSUM scoring systems in assessing outcome after laparoscopic colectomy. Br J Surg 90(10):1280–1284CrossRefPubMed Senagore AJ, Delaney CP, Duepree HJ, Brady KM, Fazio VW (2003) Evaluation of POSSUM and P-POSSUM scoring systems in assessing outcome after laparoscopic colectomy. Br J Surg 90(10):1280–1284CrossRefPubMed
25.
Zurück zum Zitat Faggi U, Giovane A, Cardini S, Falchi S (2007) Short-term outcome in colorectal surgery. Statistical analysis about mortality, morbidity and hospital stay. Minerva Chir 62(2):101–113PubMed Faggi U, Giovane A, Cardini S, Falchi S (2007) Short-term outcome in colorectal surgery. Statistical analysis about mortality, morbidity and hospital stay. Minerva Chir 62(2):101–113PubMed
Metadaten
Titel
Predicting post-operative mortality in patients undergoing colorectal surgery using P-POSSUM and CR-POSSUM scores: a prospective study
verfasst von
Edmund Leung
Ali M. Ferjani
Nigel Stellard
Ling S. Wong
Publikationsdatum
01.12.2009
Verlag
Springer-Verlag
Erschienen in
International Journal of Colorectal Disease / Ausgabe 12/2009
Print ISSN: 0179-1958
Elektronische ISSN: 1432-1262
DOI
https://doi.org/10.1007/s00384-009-0781-4

Weitere Artikel der Ausgabe 12/2009

International Journal of Colorectal Disease 12/2009 Zur Ausgabe

Update Chirurgie

Bestellen Sie unseren Fach-Newsletter und bleiben Sie gut informiert.

S3-Leitlinie „Diagnostik und Therapie des Karpaltunnelsyndroms“

CME: 2 Punkte

Prof. Dr. med. Gregor Antoniadis Das Karpaltunnelsyndrom ist die häufigste Kompressionsneuropathie peripherer Nerven. Obwohl die Anamnese mit dem nächtlichen Einschlafen der Hand (Brachialgia parästhetica nocturna) sehr typisch ist, ist eine klinisch-neurologische Untersuchung und Elektroneurografie in manchen Fällen auch eine Neurosonografie erforderlich. Im Anfangsstadium sind konservative Maßnahmen (Handgelenksschiene, Ergotherapie) empfehlenswert. Bei nicht Ansprechen der konservativen Therapie oder Auftreten von neurologischen Ausfällen ist eine Dekompression des N. medianus am Karpaltunnel indiziert.

Prof. Dr. med. Gregor Antoniadis
Berufsverband der Deutschen Chirurgie e.V.

S2e-Leitlinie „Distale Radiusfraktur“

CME: 2 Punkte

Dr. med. Benjamin Meyknecht, PD Dr. med. Oliver Pieske Das Webinar S2e-Leitlinie „Distale Radiusfraktur“ beschäftigt sich mit Fragen und Antworten zu Diagnostik und Klassifikation sowie Möglichkeiten des Ausschlusses von Zusatzverletzungen. Die Referenten erläutern, welche Frakturen konservativ behandelt werden können und wie. Das Webinar beantwortet die Frage nach aktuellen operativen Therapiekonzepten: Welcher Zugang, welches Osteosynthesematerial? Auf was muss bei der Nachbehandlung der distalen Radiusfraktur geachtet werden?

PD Dr. med. Oliver Pieske
Dr. med. Benjamin Meyknecht
Berufsverband der Deutschen Chirurgie e.V.

S1-Leitlinie „Empfehlungen zur Therapie der akuten Appendizitis bei Erwachsenen“

CME: 2 Punkte

Dr. med. Mihailo Andric
Inhalte des Webinars zur S1-Leitlinie „Empfehlungen zur Therapie der akuten Appendizitis bei Erwachsenen“ sind die Darstellung des Projektes und des Erstellungswegs zur S1-Leitlinie, die Erläuterung der klinischen Relevanz der Klassifikation EAES 2015, die wissenschaftliche Begründung der wichtigsten Empfehlungen und die Darstellung stadiengerechter Therapieoptionen.

Dr. med. Mihailo Andric
Berufsverband der Deutschen Chirurgie e.V.