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16.03.2019 | Original Paper

Long-term follow-up of implantable cardioverter-defibrillators in Short QT syndrome

verfasst von: Ibrahim El-Battrawy, Johanna Besler, Uzair Ansari, Volker Liebe, Rainer Schimpf, Erol Tülümen, Boris Rudic, Siegfried Lang, Katja Odening, Lukas Cyganek, Christian Wolpert, Xiaobo Zhou, Martin Borggrefe, Ibrahim Akin

Erschienen in: Clinical Research in Cardiology | Ausgabe 10/2019

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Abstract

Background

Short QT syndrome (SQTS) is associated with sudden cardiac death and implantable cardioverter-defibrillator (ICD) implantation is recommended in this rare disease. However, only a few SQTS families have been reported in literature with limited follow-up data.

Objectives

In the recent study, we describe the outcome data of 57 SQTS patients receiving ICD implantation. This includes seven SQTS families consecutively admitted to our hospital between 2002 and 2017 as well as patients reported in published literature.

Methods

Seven SQTS patients admitted to our hospital were followed up. Additionally, 7 studies out of a total of 626 researched articles were identified through systematic database search (PubMed, Web of Science, Cochrane Library, and Cinahl) and their data analyzed according to our model.

Results

Complications during a median follow-up time of 67.4 months (IQR 6–162 months) were documented in 31 (54%) patients. Inappropriate shocks were seen in 33% due to T wave oversensing (8.7%), supraventricular tachycardia (19%), lead failure and fracture (21%). Further complications were infection (10%), battery depletion (7%) and psychological distress (3.5%). Appropriate shocks were documented in 19%. Three patients (5%) were treated with s-ICD due to recurrent complications of transvenous ICD.

Conclusion

ICD therapy is an effective therapy in SQTS patients. However, it is also associated with significant risk of device-related complications.

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Titel: Long-term follow-up of implantable cardioverter-defibrillators in Short QT syndrome
verfasst von: Ibrahim El-Battrawy
Johanna Besler
Uzair Ansari
Volker Liebe
Rainer Schimpf
Erol Tülümen
Boris Rudic
Siegfried Lang
Katja Odening
Lukas Cyganek
Christian Wolpert
Xiaobo Zhou
Martin Borggrefe
Ibrahim Akin
Publikationsdatum: 16.03.2019
Verlag: Springer Berlin Heidelberg
Erschienen in: Clinical Research in Cardiology / Ausgabe 10/2019
Print ISSN: 1861-0684
Elektronische ISSN: 1861-0692
DOI: https://doi.org/10.1007/s00392-019-01449-3

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Springer Medizin

Long-term follow-up of implantable cardioverter-defibrillators in Short QT syndrome

Abstract

Background

Objectives

Methods

Results

Conclusion

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Springer Medizin

Abstract

Background

Objectives

Methods

Results

Conclusion

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