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Erschienen in: European Journal of Nutrition 4/2018

12.04.2017 | Original Contribution

Effects of coconut oil consumption on energy metabolism, cardiometabolic risk markers, and appetitive responses in women with excess body fat

verfasst von: Flávia Xavier Valente, Flávia Galvão Cândido, Lílian Lelis Lopes, Desirrê Morais Dias, Samantha Dalbosco Lins Carvalho, Patrícia Feliciano Pereira, Josefina Bressan

Erschienen in: European Journal of Nutrition | Ausgabe 4/2018

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Abstract

Purpose

Virgin coconut oil (VCO) is a medium-chain fatty acid source with popularly attributed benefits on obesity management. However, its role on obesity requires elucidation due to its saturated nature. In the study herein, we investigated acute effects of VCO consumption on energy metabolism, cardiometabolic risk markers, and appetitive responses in women with excess body fat.

Methods

Fifteen adult women with excess body fat (37.43 ± 0.83%) participated in this randomized, crossover, controlled study. Two isocaloric mixed breakfasts containing 25 mL of VCO or control (extra-virgin olive oil-C) were evaluated. Resting energy expenditure (REE), fat oxidation rate (FOR), diet induced thermogenesis (DIT) and appetitive subjective responses were assessed at fasting and postprandial periods (up to 240 min). Cardiometabolic risk markers were assessed at fasting and up to 180 min postprandially.

Results

VCO did not affect REE, FOR, and DIT compared to C. In addition, VCO did not cause deleterious change in triglycerides, total cholesterol, HDL-c, LDL-c, triglycerides/HDL-c ratio, uric acid, glucose and Homeostasis Model Assessment of Insulin Resistance Index (HOMA-IR) (P time×treatment > 0.05). However, VCO suppressed less hunger (P time×treatment = 0.003), total satiety (P iAUC = 0.021) and total fullness (P iAUC = 0.035) responses than C.

Conclusions

VCO consumption did not acutely change energy metabolism and cardiometabolic risk markers when added to a mixed breakfast but promoted less appetitive responses.
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Literatur
1.
Zurück zum Zitat Hruby A, Manson JE, Qi L et al (2016) Determinants and consequences of obesity. Am J Public Heal 106:1656–1662CrossRef Hruby A, Manson JE, Qi L et al (2016) Determinants and consequences of obesity. Am J Public Heal 106:1656–1662CrossRef
2.
Zurück zum Zitat World Health Organization (2016) Obesity and overweight. WHO World Health Organization (2016) Obesity and overweight. WHO
6.
Zurück zum Zitat St-Onge M-P, Jones PJH (2002) Physiological effects of medium-chain triglycerides: potential agents in the prevention of obesity. J Nutr 132:329–332CrossRefPubMed St-Onge M-P, Jones PJH (2002) Physiological effects of medium-chain triglycerides: potential agents in the prevention of obesity. J Nutr 132:329–332CrossRefPubMed
8.
Zurück zum Zitat Poonnakasem N, Pujols KD, Chaiwanichsiri S et al (2016) Different oils and health benefit statements affect physicochemical properties, consumer liking, emotion, and purchase intent: a case of sponge cake. J Food Sci 81:S165–S173. doi:10.1111/1750-3841.13186 CrossRefPubMed Poonnakasem N, Pujols KD, Chaiwanichsiri S et al (2016) Different oils and health benefit statements affect physicochemical properties, consumer liking, emotion, and purchase intent: a case of sponge cake. J Food Sci 81:S165–S173. doi:10.​1111/​1750-3841.​13186 CrossRefPubMed
9.
Zurück zum Zitat Bendixen H, Flint A, Raben A et al (2002) Effect of 3 modified fats and a conventional fat on appetite, energy intake, energy expenditure, and substrate oxidation in healthy men. Am J Clin Nutr 75:47–56CrossRefPubMed Bendixen H, Flint A, Raben A et al (2002) Effect of 3 modified fats and a conventional fat on appetite, energy intake, energy expenditure, and substrate oxidation in healthy men. Am J Clin Nutr 75:47–56CrossRefPubMed
10.
Zurück zum Zitat White MD, Papamandjaris AA, Jones PJ (1999) Enhanced postprandial energy expenditure with medium-chain fatty acid feeding is attenuated after 14 d in premenopausal women. Am J Clin Nutr 69:883–889CrossRefPubMed White MD, Papamandjaris AA, Jones PJ (1999) Enhanced postprandial energy expenditure with medium-chain fatty acid feeding is attenuated after 14 d in premenopausal women. Am J Clin Nutr 69:883–889CrossRefPubMed
11.
Zurück zum Zitat Alexandrou E, Herzberg GR, White MD (2007) High-level medium-chain triglyceride feeding and energy expenditure in normal-weight women. Can J Physiol Pharmacol 85:507–513. doi:10.1139/y07-034 CrossRefPubMed Alexandrou E, Herzberg GR, White MD (2007) High-level medium-chain triglyceride feeding and energy expenditure in normal-weight women. Can J Physiol Pharmacol 85:507–513. doi:10.​1139/​y07-034 CrossRefPubMed
12.
Zurück zum Zitat Van Wymelbeke V, Himaya A, Louis-Sylvestre J, Fantino M (1998) Influence of medium-chain and long-chain triacylglycerols on the control of food intake in men. Am J Clin Nutr 68:226–234CrossRefPubMed Van Wymelbeke V, Himaya A, Louis-Sylvestre J, Fantino M (1998) Influence of medium-chain and long-chain triacylglycerols on the control of food intake in men. Am J Clin Nutr 68:226–234CrossRefPubMed
13.
Zurück zum Zitat Van Wymelbeke V, Louis-Sylvestre J, Fantino M (2001) Substrate oxidation and control of food intake in men after a fat-substitute meal compared with meals supplemented with an isoenergetic load of carbohydrate, long-chain triacylglycerols, or medium-chain triacylglycerols. Am J Clin Nutr 74:620–630CrossRefPubMed Van Wymelbeke V, Louis-Sylvestre J, Fantino M (2001) Substrate oxidation and control of food intake in men after a fat-substitute meal compared with meals supplemented with an isoenergetic load of carbohydrate, long-chain triacylglycerols, or medium-chain triacylglycerols. Am J Clin Nutr 74:620–630CrossRefPubMed
14.
16.
Zurück zum Zitat Nosaka N, Kasai M, Nakamura M et al (2002) Effects of dietary medium-chain triacylglycerols on serum lipoproteins and biochemical parameters in healthy men. Biosci Biotechnol Biochem 66:1713–1718CrossRefPubMed Nosaka N, Kasai M, Nakamura M et al (2002) Effects of dietary medium-chain triacylglycerols on serum lipoproteins and biochemical parameters in healthy men. Biosci Biotechnol Biochem 66:1713–1718CrossRefPubMed
18.
Zurück zum Zitat Tholstrup T, Ehnholm C, Jauhiainen M et al (2004) Effects of medium-chain fatty acids and oleic acid on blood lipids, lipoproteins, glucose, insulin, and lipid transfer protein activities. Am J Clin Nutr 79:564–569CrossRefPubMed Tholstrup T, Ehnholm C, Jauhiainen M et al (2004) Effects of medium-chain fatty acids and oleic acid on blood lipids, lipoproteins, glucose, insulin, and lipid transfer protein activities. Am J Clin Nutr 79:564–569CrossRefPubMed
21.
Zurück zum Zitat Kovacs EM, Westerterp-Plantenga MS, de Vries M, et al. (2001) Effects of 2-week ingestion of (-)-hydroxycitrate and (-)-hydroxycitrate combined with medium-chain triglycerides on satiety and food intake. Physiol Behav 74:543–549CrossRefPubMed Kovacs EM, Westerterp-Plantenga MS, de Vries M, et al. (2001) Effects of 2-week ingestion of (-)-hydroxycitrate and (-)-hydroxycitrate combined with medium-chain triglycerides on satiety and food intake. Physiol Behav 74:543–549CrossRefPubMed
22.
Zurück zum Zitat Rego Costa AC, Rosado EL, Soares-Mota M (2012) Influence of the dietary intake of medium chain triglycerides on body composition, energy expenditure and satiety: a systematic review. Nutr Hosp 27:103–8. doi: 10.1590/S0212-16112012000100011 Rego Costa AC, Rosado EL, Soares-Mota M (2012) Influence of the dietary intake of medium chain triglycerides on body composition, energy expenditure and satiety: a systematic review. Nutr Hosp 27:103–8. doi: 10.​1590/​S0212-1611201200010001​1
24.
Zurück zum Zitat Soares MJ, Cummings SJ, Mamo JCL et al (2004) The acute effects of olive oil v. cream on postprandial thermogenesis and substrate oxidation in postmenopausal women. Br J Nutr 91:245–252. doi:10.1079/BJN20031047 CrossRefPubMed Soares MJ, Cummings SJ, Mamo JCL et al (2004) The acute effects of olive oil v. cream on postprandial thermogenesis and substrate oxidation in postmenopausal women. Br J Nutr 91:245–252. doi:10.​1079/​BJN20031047 CrossRefPubMed
26.
Zurück zum Zitat Soares MJ, Piers LS, Kraai L, Shetty PS (1989) Day-to-day variations in basal metabolic rates and energy intakes of human subjects. Eur J Clin Nutr 43:465–472PubMed Soares MJ, Piers LS, Kraai L, Shetty PS (1989) Day-to-day variations in basal metabolic rates and energy intakes of human subjects. Eur J Clin Nutr 43:465–472PubMed
27.
Zurück zum Zitat Piers LS, Soares MJ, Makan T, Shetty PS (1992) Thermic effect of a meal: methodology and variation in normal young adults. Br J Nutr 67:165–175CrossRefPubMed Piers LS, Soares MJ, Makan T, Shetty PS (1992) Thermic effect of a meal: methodology and variation in normal young adults. Br J Nutr 67:165–175CrossRefPubMed
28.
Zurück zum Zitat Núcleo de Estudosde e pesquisas em Alimentação – NEPA (2011) Tabela Brasileira de Composicao de Alimentos - TACO, 4th edn. NEPA- UNICAMP, Campinas Núcleo de Estudosde e pesquisas em Alimentação – NEPA (2011) Tabela Brasileira de Composicao de Alimentos - TACO, 4th edn. NEPA- UNICAMP, Campinas
29.
Zurück zum Zitat Hartman L, Lago RC (1973) Rapid preparation of fatty acid methyl esters from lipids. Lab Pract 22:475–476 (passim) Hartman L, Lago RC (1973) Rapid preparation of fatty acid methyl esters from lipids. Lab Pract 22:475–476 (passim)
30.
Zurück zum Zitat Cummings NK, James AP, Soares MJ (2006) The acute effects of different sources of dietary calcium on postprandial energy metabolism. Br J Nutr 96:138–144CrossRefPubMed Cummings NK, James AP, Soares MJ (2006) The acute effects of different sources of dietary calcium on postprandial energy metabolism. Br J Nutr 96:138–144CrossRefPubMed
31.
Zurück zum Zitat Ferrannini E (1988) The theoretical bases of indirect calorimetry: a review. Metabolism 37:287–301CrossRefPubMed Ferrannini E (1988) The theoretical bases of indirect calorimetry: a review. Metabolism 37:287–301CrossRefPubMed
32.
Zurück zum Zitat Friedewald WT, Levy RI, Fredrickson DS (1972) Estimation of the concentration of low-density lipoprotein cholesterol in plasma, without use of the preparative ultracentrifuge. Clin Chem 18:499–502PubMed Friedewald WT, Levy RI, Fredrickson DS (1972) Estimation of the concentration of low-density lipoprotein cholesterol in plasma, without use of the preparative ultracentrifuge. Clin Chem 18:499–502PubMed
33.
Zurück zum Zitat Matthews DR, Hosker JP, Rudenski AS et al (1985) Homeostasis model assessment: insulin resistance and beta-cell function from fasting plasma glucose and insulin concentrations in man. Diabetologia 28:412–419CrossRefPubMed Matthews DR, Hosker JP, Rudenski AS et al (1985) Homeostasis model assessment: insulin resistance and beta-cell function from fasting plasma glucose and insulin concentrations in man. Diabetologia 28:412–419CrossRefPubMed
35.
Zurück zum Zitat Food and Agriculture Organization of the United Nations., Joint FAO/WHO Expert Consultation on Carbohydrates in Human Nutrition (1997 : Rome I (1998) Carbohydrates in human nutrition : report of a joint FAO/WHO expert consultation, Rome, 14-18 April 1997. World Health Organization Food and Agriculture Organization of the United Nations., Joint FAO/WHO Expert Consultation on Carbohydrates in Human Nutrition (1997 : Rome I (1998) Carbohydrates in human nutrition : report of a joint FAO/WHO expert consultation, Rome, 14-18 April 1997. World Health Organization
36.
Zurück zum Zitat Alberti KGMM, Eckel RH, Grundy SM et al (2009) Harmonizing the metabolic syndrome: a joint interim statement of the International Diabetes Federation Task Force on Epidemiology and Prevention; National Heart, Lung, and Blood Institute; American Heart Association; World Heart Federation; International. Circulation 120:1640–1645CrossRefPubMed Alberti KGMM, Eckel RH, Grundy SM et al (2009) Harmonizing the metabolic syndrome: a joint interim statement of the International Diabetes Federation Task Force on Epidemiology and Prevention; National Heart, Lung, and Blood Institute; American Heart Association; World Heart Federation; International. Circulation 120:1640–1645CrossRefPubMed
37.
38.
Zurück zum Zitat Flint A, Raben A, Blundell JE, Astrup A (2000) Reproducibility, power and validity of visual analogue scales in assessment of appetite sensations in single test meal studies. Int J Obes Relat Metab Disord 24:38–48CrossRefPubMed Flint A, Raben A, Blundell JE, Astrup A (2000) Reproducibility, power and validity of visual analogue scales in assessment of appetite sensations in single test meal studies. Int J Obes Relat Metab Disord 24:38–48CrossRefPubMed
40.
42.
Zurück zum Zitat White MD, Papamandjaris AA, Jones PJ (1999) Enhanced postprandial energy expenditure with medium-chain fatty acid feeding is attenuated after 14 d in premenopausal women. Am J Clin Nutr 69:883–889CrossRefPubMed White MD, Papamandjaris AA, Jones PJ (1999) Enhanced postprandial energy expenditure with medium-chain fatty acid feeding is attenuated after 14 d in premenopausal women. Am J Clin Nutr 69:883–889CrossRefPubMed
43.
Zurück zum Zitat St-Onge M-P, Bourque C, Jones PJH et al (2003) Medium- versus long-chain triglycerides for 27 days increases fat oxidation and energy expenditure without resulting in changes in body composition in overweight women. Int J Obes Relat Metab Disord 27:95–102. doi:10.1038/sj.ijo.0802169 CrossRefPubMed St-Onge M-P, Bourque C, Jones PJH et al (2003) Medium- versus long-chain triglycerides for 27 days increases fat oxidation and energy expenditure without resulting in changes in body composition in overweight women. Int J Obes Relat Metab Disord 27:95–102. doi:10.​1038/​sj.​ijo.​0802169 CrossRefPubMed
44.
Zurück zum Zitat Hill JO, Peters JC, Yang D et al (1989) Thermogenesis in humans during overfeeding with medium-chain triglycerides. Metabolism 38:641–648CrossRefPubMed Hill JO, Peters JC, Yang D et al (1989) Thermogenesis in humans during overfeeding with medium-chain triglycerides. Metabolism 38:641–648CrossRefPubMed
45.
Zurück zum Zitat Leyton J, Drury PJ, Crawford MA (1987) Differential oxidation of saturated and unsaturated fatty acids in vivo in the rat. Br J Nutr 57:383–393CrossRefPubMed Leyton J, Drury PJ, Crawford MA (1987) Differential oxidation of saturated and unsaturated fatty acids in vivo in the rat. Br J Nutr 57:383–393CrossRefPubMed
46.
Zurück zum Zitat DeLany JP, Windhauser MM, Champagne CM, Bray GA (2000) Differential oxidation of individual dietary fatty acids in humans. Am J Clin Nutr 72:905–911CrossRefPubMed DeLany JP, Windhauser MM, Champagne CM, Bray GA (2000) Differential oxidation of individual dietary fatty acids in humans. Am J Clin Nutr 72:905–911CrossRefPubMed
47.
Zurück zum Zitat Jones PJ, Pencharz PB, Clandinin MT (1985) Whole body oxidation of dietary fatty acids: implications for energy utilization. Am J Clin Nutr 42:769–777CrossRefPubMed Jones PJ, Pencharz PB, Clandinin MT (1985) Whole body oxidation of dietary fatty acids: implications for energy utilization. Am J Clin Nutr 42:769–777CrossRefPubMed
48.
Zurück zum Zitat Papamandjaris AA, MacDougall DE, Jones PJ (1998) Medium chain fatty acid metabolism and energy expenditure: obesity treatment implications. Life Sci 62:1203–1215CrossRefPubMed Papamandjaris AA, MacDougall DE, Jones PJ (1998) Medium chain fatty acid metabolism and energy expenditure: obesity treatment implications. Life Sci 62:1203–1215CrossRefPubMed
49.
Zurück zum Zitat Sáyago-Ayerdi SG, Vaquero MP, Schultz-Moreira A et al (2008) Utilidad y controversias del consumo de ácidos grasos de cadena media sobre el metabolismo lipoproteico y obesidad. Nutr, Hosp, p 23 Sáyago-Ayerdi SG, Vaquero MP, Schultz-Moreira A et al (2008) Utilidad y controversias del consumo de ácidos grasos de cadena media sobre el metabolismo lipoproteico y obesidad. Nutr, Hosp, p 23
50.
Zurück zum Zitat Liu Y, Wang J, Zhang R et al (2009) A good response to oil with medium- and long-chain fatty acids in body fat and blood lipid profiles of male hypertriglyceridemic subjects. Asia Pac J Clin Nutr 18:351–358PubMed Liu Y, Wang J, Zhang R et al (2009) A good response to oil with medium- and long-chain fatty acids in body fat and blood lipid profiles of male hypertriglyceridemic subjects. Asia Pac J Clin Nutr 18:351–358PubMed
51.
Zurück zum Zitat Labayen I, Forga L, Martínez JA (1999) Nutrient oxidation and metabolic rate as affected by meals containing different proportions of carbohydrate and fat, in healthy young women. Eur J Nutr 38:158–166CrossRefPubMed Labayen I, Forga L, Martínez JA (1999) Nutrient oxidation and metabolic rate as affected by meals containing different proportions of carbohydrate and fat, in healthy young women. Eur J Nutr 38:158–166CrossRefPubMed
52.
Zurück zum Zitat Ng TK, Hayes KC, DeWitt GF et al (1992) Dietary palmitic and oleic acids exert similar effects on serum cholesterol and lipoprotein profiles in normocholesterolemic men and women. J Am Coll Nutr 11:383–390CrossRefPubMed Ng TK, Hayes KC, DeWitt GF et al (1992) Dietary palmitic and oleic acids exert similar effects on serum cholesterol and lipoprotein profiles in normocholesterolemic men and women. J Am Coll Nutr 11:383–390CrossRefPubMed
53.
Zurück zum Zitat Beveridge JMR, Connell WF, Haust HL, Mayer GA (1959) Dietary cholesterol and plasma cholesterol levels in man. Can J Biochem Physiol 37:575–82CrossRefPubMed Beveridge JMR, Connell WF, Haust HL, Mayer GA (1959) Dietary cholesterol and plasma cholesterol levels in man. Can J Biochem Physiol 37:575–82CrossRefPubMed
54.
Zurück zum Zitat Roels OA, Hashim SA (1962) Influence of fatty acids on serum cholesterol. Fed Proc 21(4)Pt 2:71–76 Roels OA, Hashim SA (1962) Influence of fatty acids on serum cholesterol. Fed Proc 21(4)Pt 2:71–76
55.
Zurück zum Zitat Cater NB, Heller HJ, Denke MA (1997) Comparison of the effects of medium-chain triacylglycerols, palm oil, and high oleic acid sunflower oil on plasma triacylglycerol fatty acids and lipid and lipoprotein concentrations in humans. Am J Clin Nutr 65:41–45CrossRefPubMed Cater NB, Heller HJ, Denke MA (1997) Comparison of the effects of medium-chain triacylglycerols, palm oil, and high oleic acid sunflower oil on plasma triacylglycerol fatty acids and lipid and lipoprotein concentrations in humans. Am J Clin Nutr 65:41–45CrossRefPubMed
57.
Zurück zum Zitat Clegg ME, Pratt M, Markey O et al (2012) Addition of different fats to a carbohydrate food: impact on gastric emptying, glycaemic and satiety responses and comparison with in vitro digestion. Food Res Int 48:91–97. doi:10.1016/j.foodres.2012.02.019 CrossRef Clegg ME, Pratt M, Markey O et al (2012) Addition of different fats to a carbohydrate food: impact on gastric emptying, glycaemic and satiety responses and comparison with in vitro digestion. Food Res Int 48:91–97. doi:10.​1016/​j.​foodres.​2012.​02.​019 CrossRef
58.
Zurück zum Zitat Joannic JL, Auboiron S, Raison J et al (1997) How the degree of unsaturation of dietary fatty acids influences the glucose and insulin responses to different carbohydrates in mixed meals. Am J Clin Nutr 65:1427–1433CrossRefPubMed Joannic JL, Auboiron S, Raison J et al (1997) How the degree of unsaturation of dietary fatty acids influences the glucose and insulin responses to different carbohydrates in mixed meals. Am J Clin Nutr 65:1427–1433CrossRefPubMed
59.
Zurück zum Zitat Thomsen C, Rasmussen O, Lousen T et al (1999) Differential effects of saturated and monounsaturated fatty acids on postprandial lipemia and incretin responses in healthy subjects. Am J Clin Nutr 69:1135–1143CrossRefPubMed Thomsen C, Rasmussen O, Lousen T et al (1999) Differential effects of saturated and monounsaturated fatty acids on postprandial lipemia and incretin responses in healthy subjects. Am J Clin Nutr 69:1135–1143CrossRefPubMed
60.
Zurück zum Zitat Gatti E, Noè D, Pazzucconi F et al (1992) Differential effect of unsaturated oils and butter on blood glucose and insulin response to carbohydrate in normal volunteers. Eur J Clin Nutr 46:161–166PubMed Gatti E, Noè D, Pazzucconi F et al (1992) Differential effect of unsaturated oils and butter on blood glucose and insulin response to carbohydrate in normal volunteers. Eur J Clin Nutr 46:161–166PubMed
62.
Zurück zum Zitat de Jong AJ, Hopman WP, Jansen JB, Lamers CB (1985) Effect of medium-chain triglycerides and long-chain triglycerides on plasma pancreatic polypeptide secretion in man. Regul Pept 11:77–81CrossRefPubMed de Jong AJ, Hopman WP, Jansen JB, Lamers CB (1985) Effect of medium-chain triglycerides and long-chain triglycerides on plasma pancreatic polypeptide secretion in man. Regul Pept 11:77–81CrossRefPubMed
63.
Zurück zum Zitat Barbera R, Peracchi M, Brighenti F et al (2000) Sensations induced by medium and long chain triglycerides: role of gastric tone and hormones. Gut 46:32–36CrossRefPubMedPubMedCentral Barbera R, Peracchi M, Brighenti F et al (2000) Sensations induced by medium and long chain triglycerides: role of gastric tone and hormones. Gut 46:32–36CrossRefPubMedPubMedCentral
Metadaten
Titel
Effects of coconut oil consumption on energy metabolism, cardiometabolic risk markers, and appetitive responses in women with excess body fat
verfasst von
Flávia Xavier Valente
Flávia Galvão Cândido
Lílian Lelis Lopes
Desirrê Morais Dias
Samantha Dalbosco Lins Carvalho
Patrícia Feliciano Pereira
Josefina Bressan
Publikationsdatum
12.04.2017
Verlag
Springer Berlin Heidelberg
Erschienen in
European Journal of Nutrition / Ausgabe 4/2018
Print ISSN: 1436-6207
Elektronische ISSN: 1436-6215
DOI
https://doi.org/10.1007/s00394-017-1448-5

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