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Erschienen in: Acta Neuropathologica 3/2008

01.09.2008 | Correspondence

HMGA2 rearrangements are rare in benign lipomatous lesions of the nervous system

verfasst von: Fausto J. Rodriguez, Michele R. Erickson-Johnson, Bernd W. Scheithauer, Robert J. Spinner, Andre M. Oliveira

Erschienen in: Acta Neuropathologica | Ausgabe 3/2008

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Excerpt

Lesions composed of mature adipose tissue may arise at a variety of locations in both the central and peripheral nervous system. Of these, some are architecturally complex and may be associated with congenital malformations [1] or include additional mesenchymal elements, such as mature skeletal muscle [5]. Thus, many such lesions are hypothesized to be hamartomatous rather than neoplastic in nature. Published molecular genetic studies of these lesions are absent in the literature to our knowledge. …
Literatur
2.
Zurück zum Zitat Hess JL (1998) Chromosomal translocations in benign tumors: the HMGI proteins. Am J Clin Pathol 109:251–261PubMed Hess JL (1998) Chromosomal translocations in benign tumors: the HMGI proteins. Am J Clin Pathol 109:251–261PubMed
3.
Zurück zum Zitat Medeiros F, Erickson-Johnson MR, Keeney GL, Clayton AC, Nascimento AG, Wang X et al (2007) Frequency and characterization of HMGA2 and HMGA1 rearrangements in mesenchymal tumors of the lower genital tract. Genes Chromosomes Cancer 46:981–990. doi:10.1002/gcc.20483 PubMedCrossRef Medeiros F, Erickson-Johnson MR, Keeney GL, Clayton AC, Nascimento AG, Wang X et al (2007) Frequency and characterization of HMGA2 and HMGA1 rearrangements in mesenchymal tumors of the lower genital tract. Genes Chromosomes Cancer 46:981–990. doi:10.​1002/​gcc.​20483 PubMedCrossRef
5.
Zurück zum Zitat Scheithauer BW, Woodruff JM, Erlandson RA (1997) Tumors of the peripheral nervous system. Atlas of Tumor Pathology, Washington Scheithauer BW, Woodruff JM, Erlandson RA (1997) Tumors of the peripheral nervous system. Atlas of Tumor Pathology, Washington
Metadaten
Titel
HMGA2 rearrangements are rare in benign lipomatous lesions of the nervous system
verfasst von
Fausto J. Rodriguez
Michele R. Erickson-Johnson
Bernd W. Scheithauer
Robert J. Spinner
Andre M. Oliveira
Publikationsdatum
01.09.2008
Verlag
Springer-Verlag
Erschienen in
Acta Neuropathologica / Ausgabe 3/2008
Print ISSN: 0001-6322
Elektronische ISSN: 1432-0533
DOI
https://doi.org/10.1007/s00401-008-0412-0

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