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Archives of Gynecology and Obstetrics

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01.09.2009 | Case Report

Extraskeletal neuroectodermal tumour of the vagina: a single case report and review

verfasst von: Halima Al-tamimi, Alia A. Al-Hadi, Al-Hareth Al-Khater, Issam Al-bozom, Najla Al-sayed

Erschienen in: Archives of Gynecology and Obstetrics | Ausgabe 3/2009

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Abstract

A case report and review of an extraskeletal neuroectodermal tumour of the vagina.

Background

Ewing’s sarcoma (ES) and primitive neuroectodermal tumours (PNETs) account for approximately 6–10% of primary malignant bone tumours and, following osteosarcoma, are the second most common group of bone sarcomas in children. Ewing’s sarcoma rarely affects the genitourinary tract.

Case summary

We report a rare case of extraskeletal Ewing’s sarcoma diagnosed in a 47-year-old Indian woman presenting with a simple cystic lesion in the posterior wall of the vagina. The histopathology revealed a rare presentation of a primitive malignant extraskeletal neuroectodermal tumour.

Conclusion

As our PubMed review found only six previously reported cases of vaginal extraskeletal Ewing’s sarcoma. Presentation as vaginal masses helped in early disease detection.

Cope JU (2000) A viral aetiology of Ewing’s Sarcoma. Med Hypotheses 55(5):369–372. doi:10.1054/mehy.2000.1069 PubMedCrossRef

Gaona-Luviano P, Unda-Franco E, González-Jara L, Romero P, Medina-Franco H (2003) Primitive neuroectodermal tumour of the vagina. Gynecol Oncol 91(2):456–458. doi:10.1016/S0090-8258(03)00500-6 PubMedCrossRef

Kleinman GM, Young RH, Scully RE (1993) Primary neuroectodermal tumors of the ovary. A report of 25 cases. Am J Surg Pathol 17(8):764–778. doi:10.1097/00000478-199308000-00002 PubMedCrossRef

Kawauchi S, Fukuda T, Miyamoto S, Yoshioka J, Shirahama S, Saito T, Tsukamoto N (1998) Peripheral primitive neuroectodermal tumor of the ovary confirmed by CD99 immunostaining, karyotypic analysis, and RT-PCR for EWS/FLI-1 chimeric mRNA. Am J Surg Pathol 22(11):1417–1422. doi:10.1097/00000478-199811000-00013 PubMedCrossRef

Daya D, Lukka H, Clement PB (1992) Primitive neuroectodermal tumors of the uterus: a report of four cases. Hum Pathol 23(10):1120–1129. doi:10.1016/0046-8177(92)90030-7 PubMedCrossRef

Fraggetta F, Magro G, Vasquez E (1997) Primitive neuroectodermal tumour of the uterus with focal cartilaginous differentiation. Histopathology 30(5):483–485. doi:10.1046/j.1365-2559.1997.00525.x PubMedCrossRef

Fukunaga M, Nomura K, Endo Y, Ushigome S, Aizawa S (1996) Carcinosarcoma of the uterus with extensive neuroectodermal differentiation. Histopathology 29(6):565–570. doi:10.1046/j.1365-2559.1996.d01-532.x PubMedCrossRef

Liao X, Xin X, Lü X (2004) Primary Ewing’s sarcoma-primitive neuroectodermal tumor of the vagina. Gynecol Oncol 92(2):684–688PubMedCrossRef

Petković M, Zamolo G, Muhvić D, Coklo M, Stifter S, Antulov R (2002) The first report of extra osseous Ewing’s sarcoma in the rectovaginal septum. Tumori 88(4):345–346PubMed

10.

McCluggage WG, Sumathi VP, Nucci MR, Hirsch M, Dal Cin P, Wells M, Flanagan AM, Fisher C (2007) Ewing family of tumours involving the vulva and vagina: report of a series of four cases. J Clin Pathol 60(6):674–680 PubMedCrossRef

11.

Vang R, Taubenberger JK, Mannion CM, Bijwaard K, Malpica A, Ordonez NG, Tavassoli FA, Silver SA (2000) Primary vulvar and vaginal extraosseous Ewing’s sarcoma/peripheral neuroectodermal tumor: diagnostic confirmation with CD99 immunostaining and reverse transcriptase-polymerase chain reaction. Int J Gynecol Pathol 19(2):103–109. doi:10.1097/00004347-200004000-00002 PubMedCrossRef

12.

Farley J, D O’Boyle J, Heaton J, Remmenga S (2000) Extraosseous ewing sarcoma of the vagina. Obstet Gynecol 96:832–834, 2000 by The American College of Obstetricians and Gynecologists

13.

Falk S, Alpert M (1997) Five-year survival of patients with Ewing’s sarcoma. Surg Gynecol Obstet 1967 124:319–324. doi:10.1046/j.1365-2559.1997.00525.x

14.

Fraggetta F, Magro G, Vasquez E (1997) Primitive neuroectodermal tumour of the uterus with focal cartilaginous differentiation. Histopathology 30(5):483–485

15.

Barbieri E, Emiliani E, Zini G et al (1990) Combined therapy of localized Ewing’s sarcoma of bone: analysis of results in 100 patients. Int J Radiat Oncol Biol Phys 19:1165–1170PubMed

16.

Shankar AG, Pinkerton CR, Atra A (1999) Local therapy and other factors influencing site of relapse in patients with localised Ewing’s sarcoma. United Kingdom Children’s Cancer Study Group (UKCCSG). Eur J Cancer 35(12):1698–1704. doi:10.1016/S0959-8049(99)00144-6 PubMedCrossRef

17.

Grier HE, Krailo MD, Turbell VJ et al (2003) Addition of ifosfamide and etoposide to standard chemotherapy for Ewing’s sarcoma and primitive neuroectodermal tumor of bone. N Engl Med 348(8):694CrossRef

Titel: Extraskeletal neuroectodermal tumour of the vagina: a single case report and review
verfasst von: Halima Al-tamimi
Alia A. Al-Hadi
Al-Hareth Al-Khater
Issam Al-bozom
Najla Al-sayed
Publikationsdatum: 01.09.2009
Verlag: Springer-Verlag
Erschienen in: Archives of Gynecology and Obstetrics / Ausgabe 3/2009
Print ISSN: 0932-0067
Elektronische ISSN: 1432-0711
DOI: https://doi.org/10.1007/s00404-008-0898-7

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Extraskeletal neuroectodermal tumour of the vagina: a single case report and review

Abstract

Background

Case summary

Conclusion

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Hochrisiko-Eingriffe für postoperative Übelkeit

Adjuvante Brustkrebstherapie: Doppelt hält besser

Manche Gestagene können das Risiko für Meningeome erhöhen

Stillende Frauen haben geringeres kardiovaskuläres Risiko

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Live-Webinar: Aktuelle Leitlinien bei Herz-Kreislauf-Erkrankungen

Springer Medizin

Abstract

Background

Case summary

Conclusion

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