Skip to main content
Erschienen in: European Archives of Psychiatry and Clinical Neuroscience 7/2007

01.10.2007 | ORIGINAL PAPER

Co-occurrence patterns of anxiety, depression and alcohol use disorders

verfasst von: Naomar Almeida-Filho, MD, PhD, Ines Lessa, MD, PhD, Lucélia Magalhães, MD, Maria Jenny Araújo, RN, MSC, Estela Aquino, MD, PhD, Jair de Jesus Mari, MD, PhD

Erschienen in: European Archives of Psychiatry and Clinical Neuroscience | Ausgabe 7/2007

Einloggen, um Zugang zu erhalten

Abstract

Co-occurrence of anxiety and depressive symptoms with alcohol consumption/abuse was analyzed in a sample of 2,302 adults in Bahia, Brazil. A cross-sectional household survey collected self-reported information on social and personal health, as well as individual psychological status, with standardized techniques and trained examiners. Twelve-month prevalence was 15% for anxiety, 12% for depressive disorders and 7% for alcohol abuse/dependence. Symptom co-occurrence was more frequent for depression (94% of cases co-occurring with other diagnoses), followed by anxiety disorders (82%), and alcoholism (only 20%). There was a 74% proportion of anxiety symptoms among depressed, and a 61% proportion of depressed among anxiety sufferers. The combination of depression plus anxiety was the most prevalent in both gender groups, ranging from 17% for women to 5% for men. Comorbid combinations of alcoholism yielded low prevalences, the smallest (around 1%) being the triple combo alcoholism+anxiety+depression. Gender ratios increased substantially in the absence of comorbidity, reaching peaks in depression (F:M ratio = 13.8) and alcoholism (M:F ratio = 11.8). Set component analyses indicate strong overlapping of anxiety and depression and complementarity between depression and alcoholism, modulated by gender (women depressed, men alcoholic).
Literatur
1.
Zurück zum Zitat Almeida-Filho N, Lessa I, Magalhaes L, Araujo MJ, Aquino E, James SA, Kawachi I (2004) Social inequality and depressive disorders in Bahia, Brazil: interactions of gender, ethnicity, and social class. Soc Sci Med 59:1339–1353CrossRefPubMed Almeida-Filho N, Lessa I, Magalhaes L, Araujo MJ, Aquino E, James SA, Kawachi I (2004) Social inequality and depressive disorders in Bahia, Brazil: interactions of gender, ethnicity, and social class. Soc Sci Med 59:1339–1353CrossRefPubMed
2.
Zurück zum Zitat Almeida-Filho N, Lessa I, Magalhaes L, Araujo MJ, Aquino E, James SA, Kawachi I (2005) Social inequality and alcohol consumption-abuse in Bahia, Brazil—interactions of gender, ethnicity and social class. Soc Psychiatry Psychiatr Epidemiol 40:214-222CrossRefPubMed Almeida-Filho N, Lessa I, Magalhaes L, Araujo MJ, Aquino E, James SA, Kawachi I (2005) Social inequality and alcohol consumption-abuse in Bahia, Brazil—interactions of gender, ethnicity and social class. Soc Psychiatry Psychiatr Epidemiol 40:214-222CrossRefPubMed
3.
Zurück zum Zitat Almeida-Filho N, Mari JJ, Coutinho E, Andreoli S, Fernandes J, França J (1997) Brazilian multicentric study of psychiatric morbidity: methodological features and prevalence estimates. Br J Psychiatry 171:524–529CrossRefPubMed Almeida-Filho N, Mari JJ, Coutinho E, Andreoli S, Fernandes J, França J (1997) Brazilian multicentric study of psychiatric morbidity: methodological features and prevalence estimates. Br J Psychiatry 171:524–529CrossRefPubMed
4.
Zurück zum Zitat Andreoli SB, Almeida-Filho N, Coutinho ES, Mari JJ (2000) Psychiatric cases identification by multi-step epidemiological studies: methods, problems and applicability. Rev Saude Publica 34:475–483CrossRefPubMed Andreoli SB, Almeida-Filho N, Coutinho ES, Mari JJ (2000) Psychiatric cases identification by multi-step epidemiological studies: methods, problems and applicability. Rev Saude Publica 34:475–483CrossRefPubMed
5.
Zurück zum Zitat Andreoli SB, Blay SL, Almeida-Filho N, Coutinho ES, Mari JJ (1994) The factor structure of the QMPA—Adult Psychiatry Morbidity Questionnaire—in a community sample of Brazilian cities. Rev Saude Publica 28:249–260CrossRefPubMed Andreoli SB, Blay SL, Almeida-Filho N, Coutinho ES, Mari JJ (1994) The factor structure of the QMPA—Adult Psychiatry Morbidity Questionnaire—in a community sample of Brazilian cities. Rev Saude Publica 28:249–260CrossRefPubMed
6.
Zurück zum Zitat Andrews G, Henderson S, Hall W (2001) Prevalence, comorbidity, disability and service utilisation. Overview of the Australian National Mental Health Survey. Br J Psychiatry 178:145–153CrossRefPubMed Andrews G, Henderson S, Hall W (2001) Prevalence, comorbidity, disability and service utilisation. Overview of the Australian National Mental Health Survey. Br J Psychiatry 178:145–153CrossRefPubMed
7.
Zurück zum Zitat Angst J (1999) Modern epidemiology of anxiety: results of the Zurich cohort study. Hum Psychopharmacol Clin Exp 14:29–37CrossRef Angst J (1999) Modern epidemiology of anxiety: results of the Zurich cohort study. Hum Psychopharmacol Clin Exp 14:29–37CrossRef
8.
Zurück zum Zitat Angst J, Dobler-Mikola A (1985) The Zurich Study-VI. A continuum from depression to anxiety disorders? Eur Arch Psychiatr Neurol Sci 235:179–186CrossRef Angst J, Dobler-Mikola A (1985) The Zurich Study-VI. A continuum from depression to anxiety disorders? Eur Arch Psychiatr Neurol Sci 235:179–186CrossRef
9.
Zurück zum Zitat Angst J, Merikangas K (1997) The depressive spectrum: diagnostic classification and course. J Affect Disord 45:31–40CrossRefPubMed Angst J, Merikangas K (1997) The depressive spectrum: diagnostic classification and course. J Affect Disord 45:31–40CrossRefPubMed
10.
Zurück zum Zitat Angst J, Sellaro R, Merikangas K (2000) Depressive spectrum diagnoses. Compr Psychiatry 41(2, suppl 1):39–47CrossRefPubMed Angst J, Sellaro R, Merikangas K (2000) Depressive spectrum diagnoses. Compr Psychiatry 41(2, suppl 1):39–47CrossRefPubMed
11.
Zurück zum Zitat Angst J, Vollrath M, Merikangas K, Ernst C (1990) Comorbidity of anxiety and depression in the Zurich Cohort Study of young adults. In: JD Maser, CR Cloninger (eds) Comorbidity of mood and anxiety disorders. American Psychiatric, Washington, pp 123–137 Angst J, Vollrath M, Merikangas K, Ernst C (1990) Comorbidity of anxiety and depression in the Zurich Cohort Study of young adults. In: JD Maser, CR Cloninger (eds) Comorbidity of mood and anxiety disorders. American Psychiatric, Washington, pp 123–137
12.
Zurück zum Zitat Angst J, Gamma A, Endrass J, Rössler W, Ajdacic-Gross V, Eich D, Herrell R, Merikangas KR (2006) Is the association of alcohol use disorders with major depressive disorder a consequence of undiagnosed bipolar-II disorder? Eur Arch Psychiatr Clin Neurosci 256(7):452–57CrossRef Angst J, Gamma A, Endrass J, Rössler W, Ajdacic-Gross V, Eich D, Herrell R, Merikangas KR (2006) Is the association of alcohol use disorders with major depressive disorder a consequence of undiagnosed bipolar-II disorder? Eur Arch Psychiatr Clin Neurosci 256(7):452–57CrossRef
13.
Zurück zum Zitat Ayuso-Mateos JL, Vázquez-Barquero JL, Dowrick C, Lehtinen V, Dalgard O, Casey P, Wilkinson C, Lasa L, Page H, Dunn G, Wilkinson G, ODIN Group (2001) Depressive disorders in Europe: prevalence figures from the ODIN study. Br J Psychiatr 179:308–316CrossRef Ayuso-Mateos JL, Vázquez-Barquero JL, Dowrick C, Lehtinen V, Dalgard O, Casey P, Wilkinson C, Lasa L, Page H, Dunn G, Wilkinson G, ODIN Group (2001) Depressive disorders in Europe: prevalence figures from the ODIN study. Br J Psychiatr 179:308–316CrossRef
14.
Zurück zum Zitat Bucholz KK (1999) Nosology and epidemiology of addictive disorders and their comorbidity. Psychiatr Clin North Am 22:221–240CrossRefPubMed Bucholz KK (1999) Nosology and epidemiology of addictive disorders and their comorbidity. Psychiatr Clin North Am 22:221–240CrossRefPubMed
15.
Zurück zum Zitat Cadoret RJ, Winokur G, Langbehn D, Troughton E, Yates WR, Stewart MA (1996) Depression spectrum disease, I: The role of gene-environment interaction. Am J Psychiatr 153:892–899PubMed Cadoret RJ, Winokur G, Langbehn D, Troughton E, Yates WR, Stewart MA (1996) Depression spectrum disease, I: The role of gene-environment interaction. Am J Psychiatr 153:892–899PubMed
16.
Zurück zum Zitat Conway KP, Compton W, Stinson FS, Grant BF (2006) Lifetime comorbidity of DSM-IV mood and anxiety disorders and specific drug use disorders: results from the National Epidemiologic Survey on Alcohol and Related Conditions. J Clin Psychiatr 67:247–257CrossRef Conway KP, Compton W, Stinson FS, Grant BF (2006) Lifetime comorbidity of DSM-IV mood and anxiety disorders and specific drug use disorders: results from the National Epidemiologic Survey on Alcohol and Related Conditions. J Clin Psychiatr 67:247–257CrossRef
17.
Zurück zum Zitat Cornelius JR, Bukstein O, Salloum I, Clark D (2003) Alcohol and psychiatric comorbidity. Recent Dev Alcohol 16:361–374CrossRefPubMed Cornelius JR, Bukstein O, Salloum I, Clark D (2003) Alcohol and psychiatric comorbidity. Recent Dev Alcohol 16:361–374CrossRefPubMed
18.
Zurück zum Zitat Coutinho E, Almeida-Filho N, Mari JJ, Rodrigues L (1996) Minor psychiatric morbidity and internal migration in Brazil. Soc Psychiatry Psychiatr Epidemiol 31:173–179CrossRef Coutinho E, Almeida-Filho N, Mari JJ, Rodrigues L (1996) Minor psychiatric morbidity and internal migration in Brazil. Soc Psychiatry Psychiatr Epidemiol 31:173–179CrossRef
19.
Zurück zum Zitat de Graaf R, Bijl RV, Smit F, Vollebergh WA, Spijker J (2002) Risk factors for 12-month comorbidity of mood, anxiety, and substance use disorders: findings from the Netherlands Mental Health Survey and Incidence Study. Am J Psychiatry 159:620–629CrossRefPubMed de Graaf R, Bijl RV, Smit F, Vollebergh WA, Spijker J (2002) Risk factors for 12-month comorbidity of mood, anxiety, and substance use disorders: findings from the Netherlands Mental Health Survey and Incidence Study. Am J Psychiatry 159:620–629CrossRefPubMed
20.
Zurück zum Zitat Farrell M, Howes S, Taylor C, Lewis G, Jenkins R, Bebbington P, Jarvis M, Brugha T, Gill B, Meltzer H (1998) Substance misuse and psychiatric comorbidity: an overview of the OPCS National Psychiatric Morbidity Survey. Addict Behav 23:909–918CrossRefPubMed Farrell M, Howes S, Taylor C, Lewis G, Jenkins R, Bebbington P, Jarvis M, Brugha T, Gill B, Meltzer H (1998) Substance misuse and psychiatric comorbidity: an overview of the OPCS National Psychiatric Morbidity Survey. Addict Behav 23:909–918CrossRefPubMed
21.
Zurück zum Zitat Goldberg D (1996) A dimensional model for common mental disorders. Br J Psychiatry 168(Suppl 30):44–49 Goldberg D (1996) A dimensional model for common mental disorders. Br J Psychiatry 168(Suppl 30):44–49
22.
Zurück zum Zitat Grant BF (2000) Theoretical and observed subtypes of DSM-IV alcohol abuse and dependence in a general population sample. Drug Alcohol Depend 60:287–293CrossRefPubMed Grant BF (2000) Theoretical and observed subtypes of DSM-IV alcohol abuse and dependence in a general population sample. Drug Alcohol Depend 60:287–293CrossRefPubMed
23.
Zurück zum Zitat Grant BF, Harford TC (1995) Comorbidity between DSM-IV alcohol use disorders and major depression: results of a national survey. Drug Alcohol Depend 39:197–206CrossRefPubMed Grant BF, Harford TC (1995) Comorbidity between DSM-IV alcohol use disorders and major depression: results of a national survey. Drug Alcohol Depend 39:197–206CrossRefPubMed
24.
Zurück zum Zitat Griffin JM, Fuhrer R, Stansfeld S, Marmot M (2002) The importance of low control at work and home on depression and anxiety: do these effects vary by gender and social class? Soc Sci Med 54:783–798CrossRefPubMed Griffin JM, Fuhrer R, Stansfeld S, Marmot M (2002) The importance of low control at work and home on depression and anxiety: do these effects vary by gender and social class? Soc Sci Med 54:783–798CrossRefPubMed
25.
Zurück zum Zitat Helzer JE, Burnam A, McEvoy LT (1991) Alcohol use and dependence. In: LN Robins DA Regier (eds) Psychiatric disorders in America: the epidemiologic catchment area study. The Free Press, New York, pp 81–115 Helzer JE, Burnam A, McEvoy LT (1991) Alcohol use and dependence. In: LN Robins DA Regier (eds) Psychiatric disorders in America: the epidemiologic catchment area study. The Free Press, New York, pp 81–115
26.
Zurück zum Zitat Jenkins R, Bebbington P, Brugha T, Farrell M, Gill B, Lewis G, Meltzer H, Petticrew M (1997) The national psychiatric morbidity surveys of Great Britain - strategies and methods. Psychol Med 27:765–774CrossRefPubMed Jenkins R, Bebbington P, Brugha T, Farrell M, Gill B, Lewis G, Meltzer H, Petticrew M (1997) The national psychiatric morbidity surveys of Great Britain - strategies and methods. Psychol Med 27:765–774CrossRefPubMed
27.
Zurück zum Zitat Kandel DB, Huang FY, Davies M (2001) Comorbidity between patterns of substance use dependence and psychiatric syndromes. Drug Alcohol Depend 64:233–241CrossRefPubMed Kandel DB, Huang FY, Davies M (2001) Comorbidity between patterns of substance use dependence and psychiatric syndromes. Drug Alcohol Depend 64:233–241CrossRefPubMed
28.
Zurück zum Zitat Kaufman J, Charney D (2000) Comorbidity of mood and anxiety disorders. Depress Anxiety 12(Suppl 1):69–76CrossRefPubMed Kaufman J, Charney D (2000) Comorbidity of mood and anxiety disorders. Depress Anxiety 12(Suppl 1):69–76CrossRefPubMed
29.
Zurück zum Zitat Kendler KS, Neale MC, Kessler RC, Heath AC, Eaves LJ (1993) Major depression and phobias: the genetic and environmental sources of comorbidity. Psychol Med 23:361–371CrossRefPubMed Kendler KS, Neale MC, Kessler RC, Heath AC, Eaves LJ (1993) Major depression and phobias: the genetic and environmental sources of comorbidity. Psychol Med 23:361–371CrossRefPubMed
30.
Zurück zum Zitat Kessler RC, Berglund P, Chiu WT, Demler O, Heeringa S, Hiripi E, Jin R, Pennell BE, Walters EE, Zaslavsky A, Zheng H (2004) The US National Comorbidity Survey Replication (NCS-R): design and field procedures. Int J Methods Psychiatr Res 13:69–92CrossRefPubMed Kessler RC, Berglund P, Chiu WT, Demler O, Heeringa S, Hiripi E, Jin R, Pennell BE, Walters EE, Zaslavsky A, Zheng H (2004) The US National Comorbidity Survey Replication (NCS-R): design and field procedures. Int J Methods Psychiatr Res 13:69–92CrossRefPubMed
31.
Zurück zum Zitat Kessler RC, McGonagle KA, Zhao S, Nelson CB, Hughes M, Eshleman S, Wittchen HU, Kendler KS (1994) Lifetime and 12-month prevalence of DSM-III-R psychiatric disorders in the United States. Results from the National Comorbidity Survey. Arch Gen Psychiatry 51:8–19 Kessler RC, McGonagle KA, Zhao S, Nelson CB, Hughes M, Eshleman S, Wittchen HU, Kendler KS (1994) Lifetime and 12-month prevalence of DSM-III-R psychiatric disorders in the United States. Results from the National Comorbidity Survey. Arch Gen Psychiatry 51:8–19
32.
Zurück zum Zitat Kessler RC, Ormel J, Demler O, Stang PE (2003) Comorbid mental disorders account for the role impairment of commonly occurring chronic physical disorders: results from the National Comorbidity Survey. J Occup Environ Med 45:1257–1266CrossRefPubMed Kessler RC, Ormel J, Demler O, Stang PE (2003) Comorbid mental disorders account for the role impairment of commonly occurring chronic physical disorders: results from the National Comorbidity Survey. J Occup Environ Med 45:1257–1266CrossRefPubMed
33.
Zurück zum Zitat Kessler RC, Zhao S, Blazer DG, Swartz M (1997) Prevalence, correlates, and course of minor depression and major depression in the National Comorbidity Survey. J Affect Disord 45:19–30CrossRefPubMed Kessler RC, Zhao S, Blazer DG, Swartz M (1997) Prevalence, correlates, and course of minor depression and major depression in the National Comorbidity Survey. J Affect Disord 45:19–30CrossRefPubMed
34.
Zurück zum Zitat Knibbe RA, Bloomfield K (2001) Alcohol consumption estimates in surveys in Europe: comparability and sensitivity for gender differences. Subst Abus 22:23–38PubMed Knibbe RA, Bloomfield K (2001) Alcohol consumption estimates in surveys in Europe: comparability and sensitivity for gender differences. Subst Abus 22:23–38PubMed
35.
Zurück zum Zitat Lima AMV, Azevedo ES (1991) Factor-VIII-C, ABO blood groups and black admixture in a Brazilian sample. Hum Biol 63:77–83PubMed Lima AMV, Azevedo ES (1991) Factor-VIII-C, ABO blood groups and black admixture in a Brazilian sample. Hum Biol 63:77–83PubMed
36.
Zurück zum Zitat Lukassen J, Beaudet MP (2005) Alcohol dependence and depression among heavy drinkers in Canada. Soc Sci Med 61:1658–1667CrossRefPubMed Lukassen J, Beaudet MP (2005) Alcohol dependence and depression among heavy drinkers in Canada. Soc Sci Med 61:1658–1667CrossRefPubMed
37.
Zurück zum Zitat Merikangas KR, Angst J (1995) Comorbidity and social phobia: evidence from clinical, epidemiologic and genetic studies. Eur Arch Psychiatry Clin Neurosci 244:297–303CrossRefPubMed Merikangas KR, Angst J (1995) Comorbidity and social phobia: evidence from clinical, epidemiologic and genetic studies. Eur Arch Psychiatry Clin Neurosci 244:297–303CrossRefPubMed
38.
Zurück zum Zitat Merikangas KR, Angst J, Eaton W, Canino G, Rubio-Stipec M, Wacker H, Wittchen HU, Andrade L, Essau C, Whitaker A, Kraemer H, Robins LN, Kupfer DJ (1996) Comorbidity and boundaries of affective disorders with anxiety disorders and substance misuse: results of an international task force. Br J Psychiatry 30(Suppl):58–67 Merikangas KR, Angst J, Eaton W, Canino G, Rubio-Stipec M, Wacker H, Wittchen HU, Andrade L, Essau C, Whitaker A, Kraemer H, Robins LN, Kupfer DJ (1996) Comorbidity and boundaries of affective disorders with anxiety disorders and substance misuse: results of an international task force. Br J Psychiatry 30(Suppl):58–67
39.
Zurück zum Zitat Merikangas KR, Mehta RL, Molnar BE, Walters EE, Swendsen JD, Aguilar-Gaziola S, Bijl R, Borges G, Caraveo-Anduaga JJ, DeWit DJ, Kolody B, Vega WA, Wittchen HU, Kessler RC (1998) Comorbidity of substance use disorders with mood and anxiety disorders: results of the International Consortium in Psychiatric Epidemiology. Addict Behav 23:893–907CrossRefPubMed Merikangas KR, Mehta RL, Molnar BE, Walters EE, Swendsen JD, Aguilar-Gaziola S, Bijl R, Borges G, Caraveo-Anduaga JJ, DeWit DJ, Kolody B, Vega WA, Wittchen HU, Kessler RC (1998) Comorbidity of substance use disorders with mood and anxiety disorders: results of the International Consortium in Psychiatric Epidemiology. Addict Behav 23:893–907CrossRefPubMed
40.
Zurück zum Zitat Merikangas K, Zhang H, Avenevoli S, Acharyya S, Neuenschwander M, Angst J (2003) Longitudinal trajectories of depression and anxiety in a prospective community study. The Zurich cohort study. Arch Gen Psychiatry 60:993–1000CrossRefPubMed Merikangas K, Zhang H, Avenevoli S, Acharyya S, Neuenschwander M, Angst J (2003) Longitudinal trajectories of depression and anxiety in a prospective community study. The Zurich cohort study. Arch Gen Psychiatry 60:993–1000CrossRefPubMed
41.
Zurück zum Zitat Murray RP, Connett JE, Tyas S, Bond R, Ekuma O, Silversides CK, Barnes GE (2002) Alcohol volume, drinking pattern, and cardiovascular disease morbidity and mortality: is there a U-shaped function? Am J Epidemiol 155:242–248CrossRefPubMed Murray RP, Connett JE, Tyas S, Bond R, Ekuma O, Silversides CK, Barnes GE (2002) Alcohol volume, drinking pattern, and cardiovascular disease morbidity and mortality: is there a U-shaped function? Am J Epidemiol 155:242–248CrossRefPubMed
42.
Zurück zum Zitat Raimo EB, Schuckit MA (1998) Alcohol dependence and mood disorders. Addict Behav 23:933–946CrossRefPubMed Raimo EB, Schuckit MA (1998) Alcohol dependence and mood disorders. Addict Behav 23:933–946CrossRefPubMed
43.
Zurück zum Zitat Rehm J, Greenfield TK, Walsh G, Xie X, Robson L, Single E (1999) Assessment methods for alcohol consumption, prevalence of high risk drinking and harm: a sensitivity analysis. Int J Epidemiol 28:219–224CrossRefPubMed Rehm J, Greenfield TK, Walsh G, Xie X, Robson L, Single E (1999) Assessment methods for alcohol consumption, prevalence of high risk drinking and harm: a sensitivity analysis. Int J Epidemiol 28:219–224CrossRefPubMed
44.
Zurück zum Zitat Santana V (1982) Epidemiological survey of mental disorders in a neighborhood of Salvador, Bahia. Série de Estudos em Saúde 3(suppl.):1–122 Santana V (1982) Epidemiological survey of mental disorders in a neighborhood of Salvador, Bahia. Série de Estudos em Saúde 3(suppl.):1–122
45.
Zurück zum Zitat Santana VS, Almeida-Filho N, Rocha CO, Matos AS (1997) Proxy informant reliability and bias in epidemiological research: analysis of a screening questionnaire for mental disorders. Rev Saude Publica 31:556–565CrossRefPubMed Santana VS, Almeida-Filho N, Rocha CO, Matos AS (1997) Proxy informant reliability and bias in epidemiological research: analysis of a screening questionnaire for mental disorders. Rev Saude Publica 31:556–565CrossRefPubMed
46.
Zurück zum Zitat Torgersen S (1990) Comorbidity of major depression and anxiety disorders in twin pairs. Am J Psychiatry 147:1199–1202PubMed Torgersen S (1990) Comorbidity of major depression and anxiety disorders in twin pairs. Am J Psychiatry 147:1199–1202PubMed
47.
Zurück zum Zitat Vaillant GE (1993) Is alcoholism more often the cause or the result of depression? Harvard Rev Psychiatry 1:94–99CrossRef Vaillant GE (1993) Is alcoholism more often the cause or the result of depression? Harvard Rev Psychiatry 1:94–99CrossRef
48.
Zurück zum Zitat Wittchen HU (1996) Critical issues in the evaluation of comorbidity of psychiatric disorders. Br J Psychiatry 30(Suppl):9–16 Wittchen HU (1996) Critical issues in the evaluation of comorbidity of psychiatric disorders. Br J Psychiatry 30(Suppl):9–16
49.
Zurück zum Zitat Wittchen HU, Essau CA (1993) Comorbidity and mixed anxiety/depressive disorders: is there epidemiologic evidence? J Clin Psychiatry 54(Suppl):9–15PubMed Wittchen HU, Essau CA (1993) Comorbidity and mixed anxiety/depressive disorders: is there epidemiologic evidence? J Clin Psychiatry 54(Suppl):9–15PubMed
50.
Zurück zum Zitat Yen IH, Kaplan G (1999) Poverty area residence and changes in depression and perceived health status: evidence from the Alameda County Study. Int J Epidemiol 28:90–94CrossRefPubMed Yen IH, Kaplan G (1999) Poverty area residence and changes in depression and perceived health status: evidence from the Alameda County Study. Int J Epidemiol 28:90–94CrossRefPubMed
51.
Zurück zum Zitat Zilberman ML, Tavares H, Blume SB, el-Guebaly N (2003) Substance use disorders: sex differences and psychiatric comorbidities. Can J Psychiatry 48:5–13PubMed Zilberman ML, Tavares H, Blume SB, el-Guebaly N (2003) Substance use disorders: sex differences and psychiatric comorbidities. Can J Psychiatry 48:5–13PubMed
Metadaten
Titel
Co-occurrence patterns of anxiety, depression and alcohol use disorders
verfasst von
Naomar Almeida-Filho, MD, PhD
Ines Lessa, MD, PhD
Lucélia Magalhães, MD
Maria Jenny Araújo, RN, MSC
Estela Aquino, MD, PhD
Jair de Jesus Mari, MD, PhD
Publikationsdatum
01.10.2007
Verlag
Springer-Verlag
Erschienen in
European Archives of Psychiatry and Clinical Neuroscience / Ausgabe 7/2007
Print ISSN: 0940-1334
Elektronische ISSN: 1433-8491
DOI
https://doi.org/10.1007/s00406-007-0752-0

Weitere Artikel der Ausgabe 7/2007

European Archives of Psychiatry and Clinical Neuroscience 7/2007 Zur Ausgabe

Update Psychiatrie

Bestellen Sie unseren Fach-Newsletter und bleiben Sie gut informiert.