Erschienen in:
14.11.2017 | Population Data
Genetic characteristics of 19 STRs in Chinese Uzbek ethnic and its phylogenetic relationships with other 24 populations
verfasst von:
Xiaoye Jin, Wei Cui, Yuanyuan Wei, Yuling Mu, Qian Dong, Chong Chen, Yuxin Guo, Tingting Kong, Bofeng Zhu, Jiangang Chen
Erschienen in:
International Journal of Legal Medicine
|
Ausgabe 3/2018
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Abstract
Allelic frequencies and genetic polymorphisms of 19 short tandem repeats loci were investigated so as to provide more genetic data for forensic applications in Chinese Uzbek group; besides, we evaluated phylogenetic relationships of Uzbek group with other populations. All loci were observed to conform to Hardy-Weinberg equilibrium after Bonferroni’s correction. Two hundred and nine alleles were identified in 212 unrelated healthy Uzbek individuals and their allelic frequencies ranged from 0.0024 to 0.5259. The cumulative discrimination power and cumulative probability of exclusion were 0.999999999999999999999996501 and 0.999999998759, respectively. The results of population differentiation comparison, principal component analysis, and phylogenetic tree revealed that Uzbek group had close relationships with Uyghur and Kazakh groups.