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Erschienen in: Journal of Neurology 10/2009

01.10.2009 | Original Communication

Fear of falling is independently associated with recurrent falls in patients with Parkinson’s disease: a 1-year prospective study

verfasst von: Margaret K. Y. Mak, Marco Y. C. Pang

Erschienen in: Journal of Neurology | Ausgabe 10/2009

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Abstract

The present study aimed to examine whether fear of falling (FoF) could independently predict recurrent falls in people with Parkinson’s disease (PD). Seventy patients with PD completed the study. Thirty-two patients had fallen at least once in the previous 12 months. Most of patients with PD had moderate disease severity (Hoehn and Yahr stage III). FoF was assessed by the activities-specific balance confidence (ABC) scale. PD specific motor and balance impairment was determined by Unified PD rating scale (UPDRS). Functional mobility was measured by timed-up-and-go (TUG) test. All patients were followed for 12 months by phone interview to register monthly fall incidence. Results of stepwise discriminant analysis showed that after adjusting for the fall history (F = 32.57, P < 0.001) and UPDRS motor score (F = 25.23, P < 0.001), ABC score (F = 18.84, P < 0.001) remained as a significant predictor of recurrent falls. We further established that a cut-off ABC score of 69 (i.e. 0–100, 0 indicates no confidence and 100 indicates full confidence) demonstrated the best sensitivity (93%) in predicting future falls in PD patients. The results indicate that those with an ABC score <69 at baseline had significantly higher risk of sustaining recurrent falls in the next 12 months. Findings of the present study highlight the importance of considering FoF during fall risk assessment in patients with PD.
Literatur
1.
Zurück zum Zitat Adkin AL, Frank JS, Jog MS (2003) Fear of falling and postural control in Parkinson’s disease. Mov Disord 18:496–502PubMedCrossRef Adkin AL, Frank JS, Jog MS (2003) Fear of falling and postural control in Parkinson’s disease. Mov Disord 18:496–502PubMedCrossRef
2.
Zurück zum Zitat Ashburn A, Fazakarley L, Ballinger C, Pickering R, McLellan LD, Fitton C (2007) A randomized controlled trial of a home based exercise programme to reduce the risk of falling among people with Parkinson’s disease. J Neurol Neurosurg Psychiatry 78:678–684PubMedCrossRef Ashburn A, Fazakarley L, Ballinger C, Pickering R, McLellan LD, Fitton C (2007) A randomized controlled trial of a home based exercise programme to reduce the risk of falling among people with Parkinson’s disease. J Neurol Neurosurg Psychiatry 78:678–684PubMedCrossRef
3.
Zurück zum Zitat Ashburn A, Stack E, Pickering RM, Ward CD (2001) Predicting fallers in a community-based sample of people with Parkinson’s disease. Gerontology 47:277–281PubMedCrossRef Ashburn A, Stack E, Pickering RM, Ward CD (2001) Predicting fallers in a community-based sample of people with Parkinson’s disease. Gerontology 47:277–281PubMedCrossRef
4.
Zurück zum Zitat Bandura A (1986) Social foundations of thought and action. A social cognitive theory. Prentice hall, Englewood Cliffs Bandura A (1986) Social foundations of thought and action. A social cognitive theory. Prentice hall, Englewood Cliffs
5.
Zurück zum Zitat Bloem BR, Grimbergen YAM, Cramer M, Willemsen M, Zwinderman AH (2001) Prospective assessment of falls in Parkinson’s disease. J Neurol 248:950–958PubMedCrossRef Bloem BR, Grimbergen YAM, Cramer M, Willemsen M, Zwinderman AH (2001) Prospective assessment of falls in Parkinson’s disease. J Neurol 248:950–958PubMedCrossRef
6.
Zurück zum Zitat Clemson L, Cumming RG, Kendig H, Swann M, Heard R, Taylor K (2004) The effectiveness of a community-based program for reducing the incidence of falls in the elderly: a randomized trial. J Am Geriatr Soc 52:1487–1494PubMedCrossRef Clemson L, Cumming RG, Kendig H, Swann M, Heard R, Taylor K (2004) The effectiveness of a community-based program for reducing the incidence of falls in the elderly: a randomized trial. J Am Geriatr Soc 52:1487–1494PubMedCrossRef
7.
Zurück zum Zitat Cumming RG, Salkeld G, Thomas M, Szonyi G (2000) Prospective study of the impact of fear of falling on activities of daily living, SF-36 scores, and nursing home admission. J Gerontol A Biol Sci Med Sci 55:M299–M305PubMed Cumming RG, Salkeld G, Thomas M, Szonyi G (2000) Prospective study of the impact of fear of falling on activities of daily living, SF-36 scores, and nursing home admission. J Gerontol A Biol Sci Med Sci 55:M299–M305PubMed
8.
Zurück zum Zitat Fahn S, Elton R (1987) Unified Parkinson’s Disease Rating Scale. In: Fahn S, Marsden CD, Caine DB, Goldstein M (eds) Recent developments in Parkinson’s disease, vol 2. Macmillan Health Care information, Florham Park, pp 153–163, 293–304 Fahn S, Elton R (1987) Unified Parkinson’s Disease Rating Scale. In: Fahn S, Marsden CD, Caine DB, Goldstein M (eds) Recent developments in Parkinson’s disease, vol 2. Macmillan Health Care information, Florham Park, pp 153–163, 293–304
9.
Zurück zum Zitat Folstein MF, Folstein SE, MeHugh PR (1975) Mini-mental state: a practical method for grading the state of patients for the clinician. J Psychiatr Res 12:189–198PubMedCrossRef Folstein MF, Folstein SE, MeHugh PR (1975) Mini-mental state: a practical method for grading the state of patients for the clinician. J Psychiatr Res 12:189–198PubMedCrossRef
10.
Zurück zum Zitat Franchignoni F, Martignoni E, Ferriero G, Pasetti C (2005) Balance and fear of falling in Parkinson’s disease. Parkinsonism Relat Disord 11:427–433PubMedCrossRef Franchignoni F, Martignoni E, Ferriero G, Pasetti C (2005) Balance and fear of falling in Parkinson’s disease. Parkinsonism Relat Disord 11:427–433PubMedCrossRef
11.
Zurück zum Zitat Friedman SM, Munoz B, West SK, Rubin GS, Fried LP (2002) Falls and fear of falling: which comes first? A longitudinal prediction model suggests strategies for primary and secondary prevention. J Am Geriatr Soc 50:1329–1335PubMedCrossRef Friedman SM, Munoz B, West SK, Rubin GS, Fried LP (2002) Falls and fear of falling: which comes first? A longitudinal prediction model suggests strategies for primary and secondary prevention. J Am Geriatr Soc 50:1329–1335PubMedCrossRef
12.
Zurück zum Zitat Gray P, Hildebrand K (2000) Fall risk factors in Parkinson’s disease. J Neurosci Nurs 32:222–228PubMed Gray P, Hildebrand K (2000) Fall risk factors in Parkinson’s disease. J Neurosci Nurs 32:222–228PubMed
13.
Zurück zum Zitat Hatch J, Gill-body KM, Portney LG (2003) Determinants of balance confident in community-dwelling elderly people. Phys Ther 83:1072–1079PubMed Hatch J, Gill-body KM, Portney LG (2003) Determinants of balance confident in community-dwelling elderly people. Phys Ther 83:1072–1079PubMed
14.
Zurück zum Zitat Hirsch MA, Toole T, Maitland CG, Rider RA (2003) The effects of balance training and high-intensity resistance training on persons with idiopathic Parkinson’s disease. Arch Phys Med Rehab 84:1109–1117CrossRef Hirsch MA, Toole T, Maitland CG, Rider RA (2003) The effects of balance training and high-intensity resistance training on persons with idiopathic Parkinson’s disease. Arch Phys Med Rehab 84:1109–1117CrossRef
15.
Zurück zum Zitat Hughes AJ, Daniel SE, Kilford L, Lees AJ (1992) Accuracy of clinical diagnosis of idiopathic Parkinson’s disease: a clinico-pathological study of 100 cases. J Neurol Neurosurg Psychiatry 55:181–184PubMedCrossRef Hughes AJ, Daniel SE, Kilford L, Lees AJ (1992) Accuracy of clinical diagnosis of idiopathic Parkinson’s disease: a clinico-pathological study of 100 cases. J Neurol Neurosurg Psychiatry 55:181–184PubMedCrossRef
16.
Zurück zum Zitat Idjadi JA, Aharonoff GB, Su H, Richmond J, Egol KA, Zuckerman JD, Koval KJ (2005) Hip fracture outcomes in patients with Parkinson’s disease. Am J Orthop 34:341–346PubMed Idjadi JA, Aharonoff GB, Su H, Richmond J, Egol KA, Zuckerman JD, Koval KJ (2005) Hip fracture outcomes in patients with Parkinson’s disease. Am J Orthop 34:341–346PubMed
17.
Zurück zum Zitat Jacobs JV, Horak FB, Tran VK, Nutt JG (2006) Multiple balance tests improve the assessment of postural stability in subjects with Parkinson’s disease. J Neurol Neurosurg Psychiatry 77:322–326PubMedCrossRef Jacobs JV, Horak FB, Tran VK, Nutt JG (2006) Multiple balance tests improve the assessment of postural stability in subjects with Parkinson’s disease. J Neurol Neurosurg Psychiatry 77:322–326PubMedCrossRef
18.
Zurück zum Zitat Johnell O, Melton LJ, Atkinson EJ, O’Fallon WM, Kurland LT (1992) Fracture risk in patients with Parkinsonism: a population-based study in Olmsted County, Minnesota. Age Ageing 21:32–38PubMedCrossRef Johnell O, Melton LJ, Atkinson EJ, O’Fallon WM, Kurland LT (1992) Fracture risk in patients with Parkinsonism: a population-based study in Olmsted County, Minnesota. Age Ageing 21:32–38PubMedCrossRef
19.
Zurück zum Zitat Jonsson B, Sernbo I, Johnell O (1995) Rehabilitation of hip fracture in patients with Parkinson’s disease. Scand J Rehabil Med 27:227–230PubMed Jonsson B, Sernbo I, Johnell O (1995) Rehabilitation of hip fracture in patients with Parkinson’s disease. Scand J Rehabil Med 27:227–230PubMed
20.
Zurück zum Zitat Lamb SE, Ferrucci L, Volapto S, Fried LP, Guralnik JM (2003) Risk factors for falling in home-dwelling older women with stroke. The women’s health and aging study. Stroke 34:494–501PubMedCrossRef Lamb SE, Ferrucci L, Volapto S, Fried LP, Guralnik JM (2003) Risk factors for falling in home-dwelling older women with stroke. The women’s health and aging study. Stroke 34:494–501PubMedCrossRef
21.
Zurück zum Zitat Lee HCB, Chiu HFF, Kwong PPK (1994) Cross-validation of the Geriatric Depression Scale short form in the Hong Kong elderly. Bull Hong Kong Psychol Soc 32:72–77 Lee HCB, Chiu HFF, Kwong PPK (1994) Cross-validation of the Geriatric Depression Scale short form in the Hong Kong elderly. Bull Hong Kong Psychol Soc 32:72–77
22.
Zurück zum Zitat Lesher EL, Berryhill JS (1994) Validation of the geriatric depression scale – short form among inpatients. J Clin Psychol 50:256–260PubMedCrossRef Lesher EL, Berryhill JS (1994) Validation of the geriatric depression scale – short form among inpatients. J Clin Psychol 50:256–260PubMedCrossRef
23.
Zurück zum Zitat Mak MK, Lau AL, Law FS, Cheung CC, Wong IS (2007) Validation of the Chinese translated Activities-specific Balance Confidence scale. Arch Phys Med Rehabil 88:496–503PubMedCrossRef Mak MK, Lau AL, Law FS, Cheung CC, Wong IS (2007) Validation of the Chinese translated Activities-specific Balance Confidence scale. Arch Phys Med Rehabil 88:496–503PubMedCrossRef
24.
Zurück zum Zitat Maki BE, Mcllroy WE (1996) Influence of arousal and attention on the control of postural sway. J Vest Res 6:53–59CrossRef Maki BE, Mcllroy WE (1996) Influence of arousal and attention on the control of postural sway. J Vest Res 6:53–59CrossRef
25.
Zurück zum Zitat Metz GA, Jadavji NM, Smith LK (2005) Modulation of motor function by stress: a novel concept of the effects of stress and corticosterone on behavior. Eur J Neurosci 22:1190–1200PubMedCrossRef Metz GA, Jadavji NM, Smith LK (2005) Modulation of motor function by stress: a novel concept of the effects of stress and corticosterone on behavior. Eur J Neurosci 22:1190–1200PubMedCrossRef
26.
Zurück zum Zitat Morris S, Morris ME, Iansek R (2001) Reliability of measurements obtained with the timed “Up & Go” Test in people with Parkinson Disease. Phys Ther 81:810–818PubMed Morris S, Morris ME, Iansek R (2001) Reliability of measurements obtained with the timed “Up & Go” Test in people with Parkinson Disease. Phys Ther 81:810–818PubMed
27.
Zurück zum Zitat Myers AM, Fletcher PC, Myers AH, Sherk W (1998) Discriminative and evaluative properties of the Activities-specific Balance Confidence (ABC) Scale. J Gerontol A Biol Sci Med Sci 53A:M287–M294 Myers AM, Fletcher PC, Myers AH, Sherk W (1998) Discriminative and evaluative properties of the Activities-specific Balance Confidence (ABC) Scale. J Gerontol A Biol Sci Med Sci 53A:M287–M294
28.
Zurück zum Zitat Okumiya K, Matsubayashi K, Nakamura T, Fujisawa M, Osaki Y, Doi Y (1998) The timed “Up & Go” Test is a useful predictor of falls in community-dwelling older people. J Am Geriatr Soc 46:928–930PubMed Okumiya K, Matsubayashi K, Nakamura T, Fujisawa M, Osaki Y, Doi Y (1998) The timed “Up & Go” Test is a useful predictor of falls in community-dwelling older people. J Am Geriatr Soc 46:928–930PubMed
29.
Zurück zum Zitat Pang MYC, Eng JJ (2008) Falls-related self-efficacy, but not balance and mobility performance, is related to accidental falls in chronic stroke survivors with low bone mineral density. Osteoporos Int 19:919–927PubMedCrossRef Pang MYC, Eng JJ (2008) Falls-related self-efficacy, but not balance and mobility performance, is related to accidental falls in chronic stroke survivors with low bone mineral density. Osteoporos Int 19:919–927PubMedCrossRef
30.
Zurück zum Zitat Pickering RM, Grimbergen YA, Rigney U, Ashburn A, Mazibrada G, Wood B, Gray P, Kerr G, Bloem BR (2007) A meta-analysis of six prospective studies of falling in Parkinson’s disease. Mov Disord 22:1892–1900PubMedCrossRef Pickering RM, Grimbergen YA, Rigney U, Ashburn A, Mazibrada G, Wood B, Gray P, Kerr G, Bloem BR (2007) A meta-analysis of six prospective studies of falling in Parkinson’s disease. Mov Disord 22:1892–1900PubMedCrossRef
31.
Zurück zum Zitat Podsiadlo D, Richardson S (1991) The timed “Up & Go”: a test of basic functional mobility for frail elderly. J Am Geriatr Soc 39:142–148PubMed Podsiadlo D, Richardson S (1991) The timed “Up & Go”: a test of basic functional mobility for frail elderly. J Am Geriatr Soc 39:142–148PubMed
32.
Zurück zum Zitat Powell LE, Myers AM (1995) The Activities-specific Balance Confidence (ABC) Scale. J Gerontol A Biol Sci Med Sci 50A:M28–M34PubMed Powell LE, Myers AM (1995) The Activities-specific Balance Confidence (ABC) Scale. J Gerontol A Biol Sci Med Sci 50A:M28–M34PubMed
33.
Zurück zum Zitat Sato Y, Kaji M, Tsuru T, Oizumi K (2001) Risk factors for hip fracture among elderly patients with Parkinson’s disease. J Neurol Sci 82:89–93CrossRef Sato Y, Kaji M, Tsuru T, Oizumi K (2001) Risk factors for hip fracture among elderly patients with Parkinson’s disease. J Neurol Sci 82:89–93CrossRef
34.
Zurück zum Zitat Seeman TE, Berkman LF, Gulanski BI, Robbins RJ, Greenspan SL, Charpentier PA, Rowe JW (1995) Self-esteem and neuroendocrine response to challenge: MacArthur studies of successful aging. J Psychosom Res 39:69–84PubMedCrossRef Seeman TE, Berkman LF, Gulanski BI, Robbins RJ, Greenspan SL, Charpentier PA, Rowe JW (1995) Self-esteem and neuroendocrine response to challenge: MacArthur studies of successful aging. J Psychosom Res 39:69–84PubMedCrossRef
35.
Zurück zum Zitat Tennstedt S, Howland J, Lachman M, Peterson E, Kasten L, Jette A (1998) A randomized, controlled trial of a group intervention to reduce fear of falling an associated activity restriction in older adults. J Gerontol B Psychol Sci Soc Sci 53B:P384–P392 Tennstedt S, Howland J, Lachman M, Peterson E, Kasten L, Jette A (1998) A randomized, controlled trial of a group intervention to reduce fear of falling an associated activity restriction in older adults. J Gerontol B Psychol Sci Soc Sci 53B:P384–P392
36.
Zurück zum Zitat Tinetti ME, Speechley M, Ginter SF (1988) Risk factors for falls among elderly persons living in the community. N Engl J Med 319:1701–1707PubMed Tinetti ME, Speechley M, Ginter SF (1988) Risk factors for falls among elderly persons living in the community. N Engl J Med 319:1701–1707PubMed
37.
Zurück zum Zitat Wilson MM, Miller DK, Andresen EM, Malmstrom TK, Miller JP, Wolinsky FD (2005) Fear of falling and related activity restriction among middle-aged African Americans. J Gerontol A Biol Sci Med Sci 60:355–360PubMed Wilson MM, Miller DK, Andresen EM, Malmstrom TK, Miller JP, Wolinsky FD (2005) Fear of falling and related activity restriction among middle-aged African Americans. J Gerontol A Biol Sci Med Sci 60:355–360PubMed
38.
Zurück zum Zitat Wood BH, Bilclough JA, Boweon A, Waler RW (2002) Incidence and prediction of falls in Parkinson’s disease: a prospective multidisciplinary study. J Neurol Neurosurg Psychiatry 72:721–725PubMedCrossRef Wood BH, Bilclough JA, Boweon A, Waler RW (2002) Incidence and prediction of falls in Parkinson’s disease: a prospective multidisciplinary study. J Neurol Neurosurg Psychiatry 72:721–725PubMedCrossRef
Metadaten
Titel
Fear of falling is independently associated with recurrent falls in patients with Parkinson’s disease: a 1-year prospective study
verfasst von
Margaret K. Y. Mak
Marco Y. C. Pang
Publikationsdatum
01.10.2009
Verlag
D. Steinkopff-Verlag
Erschienen in
Journal of Neurology / Ausgabe 10/2009
Print ISSN: 0340-5354
Elektronische ISSN: 1432-1459
DOI
https://doi.org/10.1007/s00415-009-5184-5

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