Erschienen in:
01.12.2012 | Short Commentary
Psoriasis during natalizumab treatment for multiple sclerosis
verfasst von:
Jorge Millán-Pascual, Laura Turpín-Fenoll, Pablo Del Saz-Saucedo, Ignacio Rueda-Medina, Santiago Navarro-Muñoz
Erschienen in:
Journal of Neurology
|
Ausgabe 12/2012
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Abstract
Beta-interferon therapy is known to trigger psoriasis, but this effect has not been previously reported for other multiple sclerosis treatments, such as natalizumab. The following is a case report. A 31-year-old woman affected by psoriasis and relapsing–remitting multiple sclerosis suffered a severe worsening of psoriasis symptoms during natalizumab treatment and acquired a drug-resistant course. This case suggests that aggravation of psoriasis might be a rare side effect of natalizumab, and that clinicians should be aware of the possibility of paradoxical activation of autoimmune diseases during its treatment.