Skip to main content
Erschienen in: Graefe's Archive for Clinical and Experimental Ophthalmology 7/2003

01.07.2003 | Short Communication

Clinical findings in macular hole surgery with indocyanine green-assisted peeling of the internal limiting membrane

verfasst von: S. Wolf, M. B. Reichel, P. Wiedemann, U. E. K. Schnurrbusch

Erschienen in: Graefe's Archive for Clinical and Experimental Ophthalmology | Ausgabe 7/2003

Einloggen, um Zugang zu erhalten

Abstract

Purpose

Indocyanine green (ICG) staining of the internal limiting membrane has facilitated ILM peeling in macular hole surgery. However, it has been reported that ICG-assisted peeling of the ILM may result in retinal damage and unfavorable functional outcome. Therefore, we analyzed our visual and anatomical results of ICG assisted macular hole surgery.

Methods

In a retrospective study the records of a consecutive series of 37 patients with full-thickness idiopathic macular holes operated with ICG-assisted ILM peeling by a single surgeon were analyzed. All patients underwent a standard three-port vitrectomy with surgically induced posterior vitreous detachment, staining of the ILM with ICG, peeling of the ILM in a circular manner around the fovea, and SF6 20% endotamponade.

Results

A total of 37 patients (37 eyes) were included in the study. The mean age was 69±7 years (range 52–81 years), and there were 26 women and 11 men. The follow-up ranged from 6 to 30 months (mean 18±6 months). At baseline visual acuity ranged from 20/400 to 20/40. Anatomically, 13 eyes had stage 2 holes, 21 eyes (57%) stage 3 holes, and three eyes stage 4 holes. At the postoperative visit (8–12 weeks after surgery) anatomical closure of the macular hole was achieved in 36 eyes. Visual acuity ranged between 20/400 and 20/20. At the last follow-up after initial surgery the macular hole was closed in all eyes. Visual acuity ranged from 20/200 to 20/20.

Conclusion

In our retrospective series anatomical and functional results of macular hole surgery with ICG-assisted peeling of the ILM are satisfactory. Primary hole closure was achieved in 97% of eyes and visual acuity increased in 62% of eyes in our series.
Literatur
1.
Zurück zum Zitat Banker AS, Freeman WR, Jung WK, Munguia D, Azen SP, Group TVFMHS (1997) Vision-threatening complications of surgery for full-thickness macular holes. Ophthalmology 104(9):1442–1453 Banker AS, Freeman WR, Jung WK, Munguia D, Azen SP, Group TVFMHS (1997) Vision-threatening complications of surgery for full-thickness macular holes. Ophthalmology 104(9):1442–1453
2.
Zurück zum Zitat Burk SE, Da Mata AP, Snyder ME, Rosa RH, Foster RE (2000) Indocyanine green-assisted peeling of the retinal internal limiting membrane. Ophthalmology 107(11):2010–2014CrossRefPubMed Burk SE, Da Mata AP, Snyder ME, Rosa RH, Foster RE (2000) Indocyanine green-assisted peeling of the retinal internal limiting membrane. Ophthalmology 107(11):2010–2014CrossRefPubMed
3.
Zurück zum Zitat Clarkson JG, Green WR, Massof D (1977) A histopathologic review of 168 cases of preretinal membrane. Am J Ophthalmol 84(1):1–17PubMed Clarkson JG, Green WR, Massof D (1977) A histopathologic review of 168 cases of preretinal membrane. Am J Ophthalmol 84(1):1–17PubMed
4.
Zurück zum Zitat Da Mata AP, Burk SE, Riemann CD, Rosa RH Jr, Snyder ME, Petersen MR, Foster RE (2001) Indocyanine green-assisted peeling of the retinal internal limiting membrane during vitrectomy surgery for macular hole repair. Ophthalmology 108:1187–1192 Da Mata AP, Burk SE, Riemann CD, Rosa RH Jr, Snyder ME, Petersen MR, Foster RE (2001) Indocyanine green-assisted peeling of the retinal internal limiting membrane during vitrectomy surgery for macular hole repair. Ophthalmology 108:1187–1192
5.
Zurück zum Zitat Eckardt C, Eckardt U, Groos S, Luciano L, Reale E (1997) [Removal of the internal limiting membrane in macular holes. Clinical and morphological findings]. Ophthalmologe 94(8):545–551CrossRefPubMed Eckardt C, Eckardt U, Groos S, Luciano L, Reale E (1997) [Removal of the internal limiting membrane in macular holes. Clinical and morphological findings]. Ophthalmologe 94(8):545–551CrossRefPubMed
6.
Zurück zum Zitat Ezra E, Aylward WG, Gregor ZJ (1997) Membranectomy and autologous serum for the retreatment of full-thickness macular holes. Arch Ophthalmol 115(10):1276–1280PubMed Ezra E, Aylward WG, Gregor ZJ (1997) Membranectomy and autologous serum for the retreatment of full-thickness macular holes. Arch Ophthalmol 115(10):1276–1280PubMed
7.
Zurück zum Zitat Faude F, Edel E, Dannhauer M, Petzel C, Meier P, Wiedemann P (1997) Autologe Thrombozytenapplikation bei der Behandlung des idiopatischen Makulaforamens. Ophthalmologe 94:877–881CrossRefPubMed Faude F, Edel E, Dannhauer M, Petzel C, Meier P, Wiedemann P (1997) Autologe Thrombozytenapplikation bei der Behandlung des idiopatischen Makulaforamens. Ophthalmologe 94:877–881CrossRefPubMed
8.
Zurück zum Zitat Fine BS (1961) Limiting membranes of sensory retina and pigment epithelium. An electron microscopic study. Arch Ophthalmol 66:847–860 Fine BS (1961) Limiting membranes of sensory retina and pigment epithelium. An electron microscopic study. Arch Ophthalmol 66:847–860
9.
Zurück zum Zitat Freeman WR, Azen SP, Kim JW, El-Haig W, Mishell DR, Bailey I (1997) Vitrectomy for the treatment of full-thickness stage 3 or 4 macular holes. Arch Ophthalmol 115:11–21PubMed Freeman WR, Azen SP, Kim JW, El-Haig W, Mishell DR, Bailey I (1997) Vitrectomy for the treatment of full-thickness stage 3 or 4 macular holes. Arch Ophthalmol 115:11–21PubMed
10.
Zurück zum Zitat Gass JDM (1988) Idiopathic senile macular hole: its early stages and pathogenesis. Arch Ophthalmol 110:629–639 Gass JDM (1988) Idiopathic senile macular hole: its early stages and pathogenesis. Arch Ophthalmol 110:629–639
11.
Zurück zum Zitat Gass JDM (1995) Reappraisal of biomicroscopic classification of stages of development of a macular hole. Am J Ophthalmol 119:752–759 Gass JDM (1995) Reappraisal of biomicroscopic classification of stages of development of a macular hole. Am J Ophthalmol 119:752–759
12.
Zurück zum Zitat Gaudric A, Paques M, Massin P, Santiago PY, Dosquet C (1997) Use of autologous platelet concentrate in macular hole surgery: report of 77 cases. Dev Ophthalmol 29:30–35PubMed Gaudric A, Paques M, Massin P, Santiago PY, Dosquet C (1997) Use of autologous platelet concentrate in macular hole surgery: report of 77 cases. Dev Ophthalmol 29:30–35PubMed
13.
Zurück zum Zitat Gaudric A, Haouchine B, Massin P, Paques M, Blain P, Erginay A (1999) Macular hole formation: new data provided by optical coherence tomography. Arch Ophthalmol 117(6):744–751PubMed Gaudric A, Haouchine B, Massin P, Paques M, Blain P, Erginay A (1999) Macular hole formation: new data provided by optical coherence tomography. Arch Ophthalmol 117(6):744–751PubMed
14.
Zurück zum Zitat Guyer DR, Green WR, de Bustros S, Fine SL (1990) Histopathologic features of idiopathic macular holes and cysts. Ophthalmology 97:1045–1051PubMed Guyer DR, Green WR, de Bustros S, Fine SL (1990) Histopathologic features of idiopathic macular holes and cysts. Ophthalmology 97:1045–1051PubMed
15.
Zurück zum Zitat Haritoglou C, Gandorfer A, Gass CA, Kampik A (2002) Indocyanine green staining and removal of internal limiting membrane in macular hole surgery: histology and outcome. Am J Ophthalmol 133(4):587–588; author reply 588CrossRefPubMed Haritoglou C, Gandorfer A, Gass CA, Kampik A (2002) Indocyanine green staining and removal of internal limiting membrane in macular hole surgery: histology and outcome. Am J Ophthalmol 133(4):587–588; author reply 588CrossRefPubMed
16.
Zurück zum Zitat Haritoglou C, Gass CA, Schaumberger M, Ehrt O, Gandorfer A, Kampik A (2001) Macular changes after peeling of the internal limiting membrane in macular hole surgery. Am J Ophthalmol 132:363–368CrossRefPubMed Haritoglou C, Gass CA, Schaumberger M, Ehrt O, Gandorfer A, Kampik A (2001) Macular changes after peeling of the internal limiting membrane in macular hole surgery. Am J Ophthalmol 132:363–368CrossRefPubMed
17.
Zurück zum Zitat Haritoglou C, Gandorfer A, Gass CA, Schaumberger M, Ulbig MW, Kampik A (2002) Indocyanine green-assisted peeling of the internal limiting membrane in macular hole surgery affects visual outcome: a clinicopathologic correlation. Am J Ophthalmol 134(6):836–841CrossRef Haritoglou C, Gandorfer A, Gass CA, Schaumberger M, Ulbig MW, Kampik A (2002) Indocyanine green-assisted peeling of the internal limiting membrane in macular hole surgery affects visual outcome: a clinicopathologic correlation. Am J Ophthalmol 134(6):836–841CrossRef
18.
Zurück zum Zitat Horiguchi M, Miyake K, Ohta I, Ito Y (1998) Staining of the lens capsule for circular continuous capsulorrhexis in eyes with white cataract. Arch Ophthalmol 116(4):535–537 Horiguchi M, Miyake K, Ohta I, Ito Y (1998) Staining of the lens capsule for circular continuous capsulorrhexis in eyes with white cataract. Arch Ophthalmol 116(4):535–537
19.
Zurück zum Zitat Hutton WL, Fuller DG, Snyder WB, Fellman RL, Swanson WH (1996) Visual field defects after macular hole surgery. Ophthalmology 103(12):2152–2159PubMed Hutton WL, Fuller DG, Snyder WB, Fellman RL, Swanson WH (1996) Visual field defects after macular hole surgery. Ophthalmology 103(12):2152–2159PubMed
20.
Zurück zum Zitat Johnson RN, Gass JD (1988) Idiopathic macular holes. Observations, stages of formation, and implications for surgical intervention. Ophthalmology 95(7):917–924PubMed Johnson RN, Gass JD (1988) Idiopathic macular holes. Observations, stages of formation, and implications for surgical intervention. Ophthalmology 95(7):917–924PubMed
21.
Zurück zum Zitat Kim JW, Freeman WR, el-Haig W, Maguire AM, Arevalo JF, Azen SP (1995) Baseline characteristics, natural history, and risk factors to progression in eyes with stage 2 macular holes. Results from a prospective randomized clinical trial. Vitrectomy for Macular Hole Study Group. Ophthalmology 102(12):1818–1828; discussion 1828–1829PubMed Kim JW, Freeman WR, el-Haig W, Maguire AM, Arevalo JF, Azen SP (1995) Baseline characteristics, natural history, and risk factors to progression in eyes with stage 2 macular holes. Results from a prospective randomized clinical trial. Vitrectomy for Macular Hole Study Group. Ophthalmology 102(12):1818–1828; discussion 1828–1829PubMed
22.
Zurück zum Zitat Kim JW, Freeman WR, Azen SP, el-Haig W, Klein DJ, Bailey IL (1996) Prospective randomized trial of vitrectomy or observation for stage 2 macular holes. Vitrectomy for Macular Hole Study Group. Am J Ophthalmol 121(6):605–614PubMed Kim JW, Freeman WR, Azen SP, el-Haig W, Klein DJ, Bailey IL (1996) Prospective randomized trial of vitrectomy or observation for stage 2 macular holes. Vitrectomy for Macular Hole Study Group. Am J Ophthalmol 121(6):605–614PubMed
23.
Zurück zum Zitat Leonard RE 2nd, Smiddy WE, Flynn HW Jr, Feuer W (1997) Long-term visual outcomes in patients with successful macular hole surgery. Ophthalmology 104(10):1648–1652PubMed Leonard RE 2nd, Smiddy WE, Flynn HW Jr, Feuer W (1997) Long-term visual outcomes in patients with successful macular hole surgery. Ophthalmology 104(10):1648–1652PubMed
24.
Zurück zum Zitat Livingstone BI, Bourke RD (1999) Retrospective study of macular holes treated with pars plana vitrectomy. Aust N Z J Ophthalmol 27(5):331–341CrossRefPubMed Livingstone BI, Bourke RD (1999) Retrospective study of macular holes treated with pars plana vitrectomy. Aust N Z J Ophthalmol 27(5):331–341CrossRefPubMed
25.
Zurück zum Zitat Maguire AM, Smiddy WE, Nanda SK, Michels RG, de la Cruz Z, Green WR (1990) Clinicopathologic correlation of recurrent epiretinal membranes after previous surgical removal. Retina 10(3):213–222PubMed Maguire AM, Smiddy WE, Nanda SK, Michels RG, de la Cruz Z, Green WR (1990) Clinicopathologic correlation of recurrent epiretinal membranes after previous surgical removal. Retina 10(3):213–222PubMed
26.
Zurück zum Zitat Michels RG (1982) A clinical and histopathologic study of epiretinal membranes affecting the macula and removed by vitreous surgery. Trans Am Ophthalmol Soc 80:580–656 Michels RG (1982) A clinical and histopathologic study of epiretinal membranes affecting the macula and removed by vitreous surgery. Trans Am Ophthalmol Soc 80:580–656
27.
Zurück zum Zitat Olsen TW, Sternberg P, Capone A, Martin DF, Lim JI, Grossniklaus HE, Aaberg TM (1998) Macular hole surgery using thrombin-activated fibrinogen and selective removal of the internal limiting membrane. Retina 18:322–329PubMed Olsen TW, Sternberg P, Capone A, Martin DF, Lim JI, Grossniklaus HE, Aaberg TM (1998) Macular hole surgery using thrombin-activated fibrinogen and selective removal of the internal limiting membrane. Retina 18:322–329PubMed
28.
Zurück zum Zitat Paques M, Chastang C, Mathis A, Sahel J, Massin P, Dosquet C, Korobelnik J-F, Le Gargasson J-F, Gaudric A (1999) Effect of autologous platelet concentrate in surgery for idiopathic macular hole. Ophthalmology 106(5):932–938PubMed Paques M, Chastang C, Mathis A, Sahel J, Massin P, Dosquet C, Korobelnik J-F, Le Gargasson J-F, Gaudric A (1999) Effect of autologous platelet concentrate in surgery for idiopathic macular hole. Ophthalmology 106(5):932–938PubMed
29.
Zurück zum Zitat Park DW, Sipperley JO, Sneed SR, Dugel PU, Jacobsen J (1999) Macular hole surgery with international-limiting membrane peeling and intravitreous air. Ophthalmology 106(7):1392–1398PubMed Park DW, Sipperley JO, Sneed SR, Dugel PU, Jacobsen J (1999) Macular hole surgery with international-limiting membrane peeling and intravitreous air. Ophthalmology 106(7):1392–1398PubMed
30.
Zurück zum Zitat Scott IU, Smiddy WE, Merikansky A, Feuer W (1997) Vitreoretinal surgery outcomes. Impact on bilateral visual function. Ophthalmology 104(6):1041–1048PubMed Scott IU, Smiddy WE, Merikansky A, Feuer W (1997) Vitreoretinal surgery outcomes. Impact on bilateral visual function. Ophthalmology 104(6):1041–1048PubMed
31.
Zurück zum Zitat Smiddy WE, Michels RG, Glaser BM, de Bustros S (1988) Vitrectomy for impending idiopathic macular holes. Am J Ophthalmol 105(4):371–376PubMed Smiddy WE, Michels RG, Glaser BM, de Bustros S (1988) Vitrectomy for impending idiopathic macular holes. Am J Ophthalmol 105(4):371–376PubMed
32.
Zurück zum Zitat Smiddy WE, Michels RG, de Bustros S, de la Cruz Z, Green WR (1989) Histopathology of tissue removed during vitrectomy for impending idiopathic macular holes. Am J Ophthalmol 108(4):360–364PubMed Smiddy WE, Michels RG, de Bustros S, de la Cruz Z, Green WR (1989) Histopathology of tissue removed during vitrectomy for impending idiopathic macular holes. Am J Ophthalmol 108(4):360–364PubMed
33.
Zurück zum Zitat Smiddy WE, Michels RG, Green WR (1990) Morphology, pathology, and surgery of idiopathic vitreoretinal macular disorders. A review. Retina 10(4):288–296PubMed Smiddy WE, Michels RG, Green WR (1990) Morphology, pathology, and surgery of idiopathic vitreoretinal macular disorders. A review. Retina 10(4):288–296PubMed
34.
Zurück zum Zitat Weinberger AWA, Schlossmacher B, Dahlke C, Hermel M, Kirchhof B, Schrage NF (2002) Indocyanine-green-assisted internal limiting membrane peeling in macular hole surgery—a follow-up study. Graefe's Arch Clin Exp Ophthalmol 240(11):913–917 Weinberger AWA, Schlossmacher B, Dahlke C, Hermel M, Kirchhof B, Schrage NF (2002) Indocyanine-green-assisted internal limiting membrane peeling in macular hole surgery—a follow-up study. Graefe's Arch Clin Exp Ophthalmol 240(11):913–917
35.
Zurück zum Zitat Yooh HS, Brooks HL, Capone A, L'Hernault NL, Grossniklaus HE (1996) Ultrastructural features of tissue removed during idiopathic macular hole surgery. Am J Ophthalmol 122(1):67–75PubMed Yooh HS, Brooks HL, Capone A, L'Hernault NL, Grossniklaus HE (1996) Ultrastructural features of tissue removed during idiopathic macular hole surgery. Am J Ophthalmol 122(1):67–75PubMed
Metadaten
Titel
Clinical findings in macular hole surgery with indocyanine green-assisted peeling of the internal limiting membrane
verfasst von
S. Wolf
M. B. Reichel
P. Wiedemann
U. E. K. Schnurrbusch
Publikationsdatum
01.07.2003
Verlag
Springer-Verlag
Erschienen in
Graefe's Archive for Clinical and Experimental Ophthalmology / Ausgabe 7/2003
Print ISSN: 0721-832X
Elektronische ISSN: 1435-702X
DOI
https://doi.org/10.1007/s00417-003-0673-1

Weitere Artikel der Ausgabe 7/2003

Graefe's Archive for Clinical and Experimental Ophthalmology 7/2003 Zur Ausgabe

Neu im Fachgebiet Augenheilkunde

Update Augenheilkunde

Bestellen Sie unseren Fach-Newsletter und bleiben Sie gut informiert.