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Erschienen in: Graefe's Archive for Clinical and Experimental Ophthalmology 3/2005

01.03.2005 | Short Communication

Visual improvement during psychophysical training in an adult amblyopic eye following visual loss in the contralateral eye

verfasst von: Maria Fronius, Licia Cirina, Angelika Cordey, Christian Ohrloff

Erschienen in: Graefe's Archive for Clinical and Experimental Ophthalmology | Ausgabe 3/2005

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Abstract

Background

Recent publications have demonstrated neural plasticity in adult amblyopes subjected to psychophysical training based on perceptual learning. The purpose of this case report is to present rarely available prospective data of visual acuity development in a strabismic amblyope undergoing psychophysical training and pleoptic treatment after loss of function of the non-amblyopic eye.

Methods

The design is a prospective, observational and interventional case report. Visual acuity was tested monthly, with constant optical correction. The 60-year-old female patient participated in a psychophysical training implemented in our laboratory, and in pleoptic treatment.

Results

Slow functional improvement of the amblyopic eye was observed during a period of 10 months, both in the tests used for training and in visual acuity: single optotypes increased by 4 chart lines, crowded optotypes by 2–3 lines.

Conclusions

To our knowledge, this is the first report of the new approach of perceptual learning in an adult amblyope after loss of vision in the contralateral eye. Our results represent further evidence that the visual system of adult amblyopes preserves a certain degree of neural plasticity, whether spontaneous or enhanced by training. Furthermore, that plasticity in adults is limited, and early diagnosis and treatment of amblyopia must remain the primary goal.
Literatur
1.
Zurück zum Zitat El Mallah M, Chakravarthy U, Hart P (2000) Amblyopia: is visual loss permanent? Br J Ophthalmol 84:952–956CrossRefPubMed El Mallah M, Chakravarthy U, Hart P (2000) Amblyopia: is visual loss permanent? Br J Ophthalmol 84:952–956CrossRefPubMed
2.
Zurück zum Zitat Fronius M, Sireteanu R, Zubcov A, Büttner A (2000) Preliminary report: monocular spatial localization in children with strabismic amblyopia. Strabismus 8:243–249CrossRefPubMed Fronius M, Sireteanu R, Zubcov A, Büttner A (2000) Preliminary report: monocular spatial localization in children with strabismic amblyopia. Strabismus 8:243–249CrossRefPubMed
3.
Zurück zum Zitat Harrad R, Williams C (2003) Prediction of improved vision in the amblyopic eye after visual loss in the non-amblyopic eye, by Rahi JS, Logan S, Cortina-Borja M, Timms C, Russel-Eggit I, Taylor D (2002) Lancet 360:597–602. Surv Ophthalmol 48:235–236CrossRef Harrad R, Williams C (2003) Prediction of improved vision in the amblyopic eye after visual loss in the non-amblyopic eye, by Rahi JS, Logan S, Cortina-Borja M, Timms C, Russel-Eggit I, Taylor D (2002) Lancet 360:597–602. Surv Ophthalmol 48:235–236CrossRef
4.
Zurück zum Zitat Karatza EC, Shields CL, Shields JA (2004) Visual improvement in an adult amblyopic eye following radiation-induced visual loss in the contralateral eye. Arch Ophthalmol 122:126–128CrossRefPubMed Karatza EC, Shields CL, Shields JA (2004) Visual improvement in an adult amblyopic eye following radiation-induced visual loss in the contralateral eye. Arch Ophthalmol 122:126–128CrossRefPubMed
5.
Zurück zum Zitat Levi DM, Polat U (1996) Neural plasticity in adults with amblyopia. Proc Natl Acad Sci USA 93:6830–6834CrossRefPubMed Levi DM, Polat U (1996) Neural plasticity in adults with amblyopia. Proc Natl Acad Sci USA 93:6830–6834CrossRefPubMed
6.
Zurück zum Zitat Moseley M, Fielder A (2001) Improvement in amblyopic eye function and contralateral eye disease. Lancet 357:902–903CrossRefPubMed Moseley M, Fielder A (2001) Improvement in amblyopic eye function and contralateral eye disease. Lancet 357:902–903CrossRefPubMed
7.
Zurück zum Zitat Pandey PK, Chaudhuri Z, Kumar M, Satyabala K, Sharma P (2002) Effect of levodopa and carbidopa in human amblyopia. J Pediatr Ophthalmol Strabismus 39:81–89PubMed Pandey PK, Chaudhuri Z, Kumar M, Satyabala K, Sharma P (2002) Effect of levodopa and carbidopa in human amblyopia. J Pediatr Ophthalmol Strabismus 39:81–89PubMed
8.
Zurück zum Zitat Polat U, Ma-Naim T, Belkin M (2001) Treatment of adult amblyopia by perceptual learning. Invest Ophthalmol Vis Sci 42:S400 Polat U, Ma-Naim T, Belkin M (2001) Treatment of adult amblyopia by perceptual learning. Invest Ophthalmol Vis Sci 42:S400
9.
Zurück zum Zitat Rahi JS, Logan S, Borja MC, Timms C, Russell-Eggitt I, Taylor D (2002) Prediction of improved vision in the amblyopic eye after visual loss in the non-amblyopic eye. Lancet 360:621–622CrossRefPubMed Rahi JS, Logan S, Borja MC, Timms C, Russell-Eggitt I, Taylor D (2002) Prediction of improved vision in the amblyopic eye after visual loss in the non-amblyopic eye. Lancet 360:621–622CrossRefPubMed
10.
Zurück zum Zitat Schulz E (1998) Levodopa-Therapie bei Amblyopie des letzten Auges im Erwachsenenalter. Klin Monatsbl Augenheilkd 212:240 Schulz E (1998) Levodopa-Therapie bei Amblyopie des letzten Auges im Erwachsenenalter. Klin Monatsbl Augenheilkd 212:240
11.
Zurück zum Zitat Vereecken EP, Brabant P (1984) Prognosis for vision in amblyopia after the loss of the good eye. Arch Ophthalmol 102:220–224PubMed Vereecken EP, Brabant P (1984) Prognosis for vision in amblyopia after the loss of the good eye. Arch Ophthalmol 102:220–224PubMed
Metadaten
Titel
Visual improvement during psychophysical training in an adult amblyopic eye following visual loss in the contralateral eye
verfasst von
Maria Fronius
Licia Cirina
Angelika Cordey
Christian Ohrloff
Publikationsdatum
01.03.2005
Erschienen in
Graefe's Archive for Clinical and Experimental Ophthalmology / Ausgabe 3/2005
Print ISSN: 0721-832X
Elektronische ISSN: 1435-702X
DOI
https://doi.org/10.1007/s00417-004-1014-8

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