Skip to main content
Erschienen in: Graefe's Archive for Clinical and Experimental Ophthalmology 12/2008

01.12.2008 | Case Report

Rapid regression of retinal hemorrhage and neovascularization in a case of familial exudative vitreoretinopathy treated with intravitreal bevacizumab

verfasst von: Mizuki Tagami, Sentaro Kusuhara, Shigeru Honda, Yasutomo Tsukahara, Akira Negi

Erschienen in: Graefe's Archive for Clinical and Experimental Ophthalmology | Ausgabe 12/2008

Einloggen, um Zugang zu erhalten

Abstract

Purpose

To report a case of familial exudative vitreoretinopathy (FEVR) rapidly resolved by intravitreal injection of bevacizumab.

Methods

A 36-year-old woman complained about floaters and visual field defect. Funduscopic examinations revealed retinal vessel anastomosis located between the equator and ora serrata in both eyes. The right eye was accompanied with slight vitreous hemorrhage. Since the patient declined retinal cryopexy for cosmetic reasons, intravitreal bevacizumab injections (1.25 mg/0.05 ml) were performed in both eyes.

Results

Treatment resulted in the rapid regression and the accelerated fibrosis of neovascular tissues. At 4-month follow-up in the right eye and 1-month follow-up in the left, no signs of systemic or ocular complications were detected.

Conclusions

Intravitreal injection of bevacizumab may be considered as an alternative method in treating FEVR.
Literatur
1.
Zurück zum Zitat Criswick VG, Schepens CL (1969) Familial exudative vitreoretinopathy. Am J Ophthalmol 68:578–594PubMed Criswick VG, Schepens CL (1969) Familial exudative vitreoretinopathy. Am J Ophthalmol 68:578–594PubMed
2.
Zurück zum Zitat van Nouhuys CE (1989) Juvenile retinal detachment as a complicaton of familial exudative vitreoretinopathy. Fortschr Ophthalmol 86:221–223PubMed van Nouhuys CE (1989) Juvenile retinal detachment as a complicaton of familial exudative vitreoretinopathy. Fortschr Ophthalmol 86:221–223PubMed
4.
7.
Zurück zum Zitat Honda S, Hirabayashi H, Tsukahara Y et al (2008) Acute contraction of the proliferative membrane after an intravitreal injection of bevacizumab for advanced retinopathy of prematurity. Graefes Arch Clin Exp Ophthalmol 246(7):1061–1063, doi:10.1007/s00417-008-0786-7 PubMedCrossRef Honda S, Hirabayashi H, Tsukahara Y et al (2008) Acute contraction of the proliferative membrane after an intravitreal injection of bevacizumab for advanced retinopathy of prematurity. Graefes Arch Clin Exp Ophthalmol 246(7):1061–1063, doi:10.​1007/​s00417-008-0786-7 PubMedCrossRef
Metadaten
Titel
Rapid regression of retinal hemorrhage and neovascularization in a case of familial exudative vitreoretinopathy treated with intravitreal bevacizumab
verfasst von
Mizuki Tagami
Sentaro Kusuhara
Shigeru Honda
Yasutomo Tsukahara
Akira Negi
Publikationsdatum
01.12.2008
Verlag
Springer-Verlag
Erschienen in
Graefe's Archive for Clinical and Experimental Ophthalmology / Ausgabe 12/2008
Print ISSN: 0721-832X
Elektronische ISSN: 1435-702X
DOI
https://doi.org/10.1007/s00417-008-0949-6

Weitere Artikel der Ausgabe 12/2008

Graefe's Archive for Clinical and Experimental Ophthalmology 12/2008 Zur Ausgabe

Neu im Fachgebiet Augenheilkunde

Update Augenheilkunde

Bestellen Sie unseren Fach-Newsletter und bleiben Sie gut informiert.