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Graefe's Archive for Clinical and Experimental Ophthalmology

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01.02.2009 | Medical Ophthalmology

Diabetic retinopathy and health-related quality of life

verfasst von: Eldad Davidov, Lusine Breitscheidel, Johannes Clouth, Marion Reips, Michael Happich

Erschienen in: Graefe's Archive for Clinical and Experimental Ophthalmology | Ausgabe 2/2009

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Abstract

Objective

To describe the impact of co-morbidities, visual acuity, diabetic retinopathy (DR) grade, and macular edema (ME) on the health-related quality of life (HRQOL) among patients with diabetic retinopathy.

Methods

Analysis of data of 207 patients with diabetic retinopathy from Germany in 2003. HRQOL assessment was done using the generic (SF-12) questionnaire. It was hypothesized that exogenous variables (co-morbidities, visual acuity impairment, DR, and ME) would have an impact on HRQOL. Using a structural equation modelling procedure, the effects of exogenous variables on endogenous variables physical component summaries (PSC) and mental component summaries (MCS) reflecting HRQOL were tested.

Results

The number of co-morbidities had a negative effect on visual acuity (b = −0.26, standardized) and a similar negative effect on PCS (b = −0.27). DR grade had a negative effect on visual acuity (b = −0.19) and a positive effect on the variable ME (b = 0.44). ME displayed a negative effect on visual acuity (b = −0.58) and also on MCS (b = −0.29). Visual acuity had a positive effect (b = 0.48) on PCS.

Conclusions

Presence of DR and ME, visual acuity impairment and patient co-morbidities lead to significant impairment of both the physical and mental components of HRQOL.

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Titel: Diabetic retinopathy and health-related quality of life
verfasst von: Eldad Davidov
Lusine Breitscheidel
Johannes Clouth
Marion Reips
Michael Happich
Publikationsdatum: 01.02.2009
Verlag: Springer-Verlag
Erschienen in: Graefe's Archive for Clinical and Experimental Ophthalmology / Ausgabe 2/2009
Print ISSN: 0721-832X
Elektronische ISSN: 1435-702X
DOI: https://doi.org/10.1007/s00417-008-0960-y

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Diabetic retinopathy and health-related quality of life

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