Skip to main content
Hauptrubriken
CME Facharzt-Training Webinare Zeitschriften Bücher e.Medpedia Podcast
Service
Jobbörse Info & Hilfe
Fachgebiete
Anästhesiologie Allgemeinmedizin Arbeitsmedizin Augenheilkunde Chirurgie Dermatologie Gynäkologie und Geburtshilfe HNO Innere Medizin Kardiologie Neurologie Onkologie und Hämatologie Orthopädie und Unfallchirurgie Pädiatrie Pathologie Psychiatrie Radiologie Rechtsmedizin Urologie Zahnmedizin
Themen
Klimawandel und Gesundheit Neues aus dem Markt COVID-19 Praxis und Beruf Seltene Erkrankungen GOÄ & EBM Panorama
Sammlungen
Kasuistiken Algorithmen & Infografiken Blickdiagnosen Arthropedia FlapFinder (für Dermatochirurgen) Videos Kongressberichterstattung Medizin für Apothekerinnen und Apotheker Für Ärztinnen und Ärzte in Weiterbildung Für Medizinstudierende
Erweiterte Suche
Anmelden
nach oben
Graefe's Archive for Clinical and Experimental Ophthalmology
Erschienen in: Graefe's Archive for Clinical and Experimental Ophthalmology 12/2009

01.12.2009 | Review Article

Silicone oil induced glaucoma: A review

verfasst von: Parul Ichhpujani, Anjana Jindal, L. Jay Katz

Erschienen in: Graefe's Archive for Clinical and Experimental Ophthalmology | Ausgabe 12/2009

Einloggen, um Zugang zu erhalten

Abstract

Background

Silicone oil has been an important adjunct for internal tamponade in the treatment of complicated retinal detachment for the past 4 decades. A known complication of its use has been the development of secondary glaucoma.

Methods

This article reviews the current body of literature documenting the different pathogeneses, predisposing factors and management of silicone oil induced pressure elevation and optic neuropathy. Categorization is clarified for the different types of secondary glaucomas due to silicone oil.

Results

Four different mechanisms have been proposed for the pathogenesis of glaucoma that require different therapeutic strategies: (1) overfill with total anterior chamber fill leads to an open-angle glaucoma due to mechanical obstruction of outflow, (2) pupillary block with silicone oil incites angle closure glaucoma, (3) denaturation of silicone oil into microdroplets may sweep into the trabecular meshwork with the development of secondary open angle glaucoma, or (4) finally, inflammation or exacerbation of pre-existing glaucoma.

Conclusion

Understanding the risk factors and the pathogenesis of secondary glaucoma when using silicone oil helps guide the timely and appropriate course of treatment.
Literatur
1.
Kreiner CF (1987) Chemical and physical aspects of clinically applied silicones. Dev Ophthalmol 14:11–19PubMed
2.
Cibis PA, Becker B, Okun E, Cowan S (1962) The use of liquid silicone in retinal detachment surgery. Arch Ophthalmol 681:590–599
3.
Sugar HS, Okumara ID (1976) Ocular findings six years after intravitreal silicone injection. Arch Ophthalmol.Arch Ophthalmol 94:612–615
4.
Watzke RC (1967) Silicone Retinopiesis for retinal detachment a long term clinical evaluation. Arch Ophthalmol 77:185–196PubMed
5.
Leaver PK, Grey RHB, Garner A (1979) Silicone oil injection in the treatment of massive pre retinal traction II. Late complications in 93 eyes. Br J Ophthalmol 63:361–367CrossRefPubMed
6.
McCuen BW, de Juan E, Landers MB, Machemer R (1985) Silicone oil in vitreoretinal surgery. II: Results and complications. Retina 5:198–205CrossRefPubMed
7.
Federman JL, Schubert HD (1988) Complications associated with the use of silicone oil in 150 cases after retina-vitreous surgery. Ophthalmology 95:870–876PubMed
8.
Chan C, Okun E (1986) The question of ocular tolerance to intravitreal liquid silicone. A long term analysis. Ophthalmology 93:651–660PubMed
9.
Nguyen QH, Llyod MA, Huer DK et al (1992) Incidence and management of glaucoma after intravitreal silicone oil injection for complicated retinal detachments. Ophthalmology 99:1520–1526PubMed
10.
Barr CC, Lai MY, Lean JS et al (1993) Postoperative intraocular pressure abnormalities in the silicone study. Silicone Study Report 4. Ophthalmology 100:1629–1635PubMed
11.
Casswell AG, Gregor ZJ (1987) Silicone oil removal II: operative and postoperative complications. Br J Ophthalmol 71:898–902CrossRefPubMed
12.
Zilis JD, McCuen BW II, deJuan E et al (1989) Results of silicone oilremoval in advanced proliferative vitreoretinopathy. Am J Ophthalmol 108:15–21PubMed
13.
Unosson K, Stenkula S, Tornqvist P, Weijdegard L (1985) 1985. Acta Ophthalmol (Copenh) 63:656–660CrossRef
14.
Zborowski-Gutman L, Triester G, Naveh N, Chen V, Blumenthal M (1987) Acute glaucoma following vitrectomy and silicone oil injection. Br J Ophthalmol 71:903–906CrossRefPubMed
15.
Han DP, Lewis H, Lambrou FH Jr et al (1989) Mechanisms of intraocular pressure elevation after pars plana vitrectomy. Ophthalmology 96:1357–1362PubMed
16.
Desai UR, Alhalel AA, Schiffman RM et al (1997) Intraocular pressure elevation after simple pars plana vitrectomy. Ophthalmology 104:781–786PubMed
17.
Burk LL, Shields MB, Proia AD et al (1988) Intraocular pressure following intravitreal silicone oil injection. Ophthalmic Surg 19:565–569PubMed
18.
Riedel KG, Gabel VP, Neubauer L et al (1990) Intravitreal silicone oil injection: Complications and treatment of 415 consecutive patients. Graefes Arch Clin Exp Ophthalmol 228:19–23CrossRefPubMed
19.
Honavar SG, Goyal M, Majji AB et al (1999) Glaucoma after pars plana vitrectomy and silicone oil injection for complicated retinal detachments. Ophthalmology 106:169–176CrossRefPubMed
20.
Henderer JD, Budenz DL, Flynn HW et al (1999) Elevated intraocular pressure and hypotony following silicone oil retinal tamponade for complex retinal detachment: Incidence and risk factors. Arch Ophthalmol 117:189–195PubMed
21.
Ardjomand N, El-Shabrawi Y (2001) Pupillary block after silicone implantation in a phakic eye. Eye 15:331PubMed
22.
Budenz DL, Taba KE, Feuer WJ et al (2001) Surgical management of secondary glaucoma after pars plana vitrectomy and silicone oil injection for complex retinal detachment. Ophthalmology 108:1628–1632CrossRefPubMed
23.
Jackson TL, Thiagarajan M, Murthy R et al (2001) Pupil block glaucoma in phakic and pseudophakic patients after vitrectomy with silicone oil injection. Am J Ophthalmol 132:414–416CrossRefPubMed
24.
Jonas JB, Knorr HL, Rank RM, Budde WM (2001) Intraocular pressure and silicone oil endotamponade. J Glaucoma 10:102–108CrossRefPubMed
25.
de Corral LR, Cohen SB, Peyman GA (1987) Effect of intravitreal silicone oil on intraocular pressure. Ophthalmic Surg 18:446–449PubMed
26.
Ni C, Wang W, Albert DM, Schepens CL (1983) Intravitreous silicone injection. Histopathologic findings in a human eye after 12 years. Arch Ophthalmol 101:1399–1401PubMed
27.
Punnonen E, Laatikainen L, Ruusuyaara P et al (1989) Silicone oil in retinal detachment surgery. Results and complications. Acta Ophthalmol 67:30–36
28.
Chan C, Okun E (1986) The question of ocular tolerance to intravitreal liquid silicone. A long-term analysis. Ophthalmology 93:651–659PubMed
29.
Laqua H, Lucke K, Foerster M (1987) Results of silicone oil surgery. Jpn J Ophthalmol 31:124–131PubMed
30.
Yeo JH, Glaser BM, Michels RG (1987) Silicone oil in the treatment of complicated retinal detachments. Ophthalmology 94:1109–1113PubMed
31.
Shields CL, Eagle RC Jr (1989) Pseudo-Schnabel’s cavernous degeneration of the optic nerve secondary to intraocular silicone oil. Arch Ophthalmol 107:714–717PubMed
32.
Knorr HLJ, Seltsam A, Holbach LM, Naumann GOH (1996) Intraokulare Silikonöltamponade. Eine klinisch-pathologische Studie an 36 enukleierten Augen [Intraocular silicone oil tamponade. A clinico-pathologic study of 36 enucleated eyes]. Ophthalmologe 93:130–138PubMed
33.
Wenkel H, Naumann GOH (1999) Retrolaminare Infiltration des Nervus opticus durch als intraokulare Tamponade verwendetes Silikonöl [Retrolaminar infiltration of optic nerve with silicone oil following instillation as intraocular tamponade]. Klin Monatsbl Augenheilkd 214:120–122CrossRefPubMed
34.
Budde M, Cursiefen C, Holbach LM, Naumann GO (2001) Silicone oil-associated optic nerve degeneration. Am J Ophthalmol 131(3):392–394CrossRefPubMed
35.
Champion R, Faulborn J, Bowald S, Erb P (1987) Peritoneal reaction to liquid silicone: an experimental study. Graefes Arch Clin Exp Ophthamol 225:141–145CrossRef
36.
Cibis PA (1965) Recent methods in the surgical treatment of retinal detachment: intravitreal procedures. Trans Ophthalmol Soc U K 85:111–127PubMed
37.
Laroche L, Pavlakis C, Saraux H, Orcel L (1983) Ocular findings following intravitreal silicone injection. Arch Ophthalmol 101:1422–1425PubMed
38.
Lucke KH, Foerster MH, Laqua H (1987) Long-term results of vitrectomy and silicone oil in 500 cases of complicated retinal detachments. Am J Ophthalmol 104:624–633PubMed
39.
Billington BM, Leaver PK (1986) Vitrectomy and fluid/silicone oil exchange for giant retinal tears: results at 18 months. Graefes Arch Clin Exp Ophthalmol 224:7–10CrossRefPubMed
40.
Valone J Jr, McCarthy M (1994) Emulsified anterior chamber silicone oil and glaucoma. Ophthalmology 101:1908–1912PubMed
41.
Fisk MJ, Cairns JD (1995) Silicone oil insertion: A review of 127 consecutive cases. Aust NZ J Ophthalmol 23:25–32CrossRef
42.
Ando F (1987) Usefulness and limit of silicone in management of complicated retinal detachment. Jpn J Ophthalmol 31:138–146PubMed
43.
Diddie KR, Azen SP, Freeman HM et al (1996) Anterior proliferative vitreoretinopathy in the silicone study: Silicone Study Report Number 10. Ophthalmology 103:1092–1099PubMed
44.
Moisseiev J, Barak A, Manaim T, Treister G (1993) Removal of silicone oil in the management of glaucoma in eyes with emulsified silicone. Retina 13:290–295CrossRefPubMed
45.
La Heij EC, Hendrikse F, Kessels AG (2001) Results and complications of temporary silicone oil tamponade in patients with complicated retinal detachments. Retina 21:107–114CrossRefPubMed
46.
Ando F (1985) Intraocular hypertension resulting from pupillary block by silicone oil. Am J Ophthalmol 99(1):87–88PubMed
47.
Laganowski HC, Leaver PK (1989) Silicone oil in the aphakic eye: the influence of a six o’clock peripheral iridectomy. Eye 3:338–348PubMed
48.
Gabel VP, Kampik A, Burkhardt J (1987) Analysis of intraocularly applied silicone oils of various origins. Graefes Arch Clin Exp Ophthalmol 225:160–162CrossRefPubMed
49.
Petersen J, Ritzau-Tondrow U (1988) Chronic glaucoma following silicone oil implantation: a comparison of two oils of differing viscosity. Fortschr Ophthalmol 85:632–634PubMed
50.
Stinson WG, Small KW (1994) Glaucoma after surgery on the retina and vitreous. Seminars in Ophthalmol 9(4):258–265CrossRef
51.
de Silva DJ, Lim KS, Schulenburg WE (2005) An experimental study on the effect of encircling band procedure on silicone oil emulsification. Br J Ophthalmol 89(10):1348–1350CrossRefPubMed
52.
Yilmaz T, Güler M (2008) The role of nystagmus in silicone oil emulsification after pars plana vitrectomy and silicone oil injection for complex retinal detachment. Eur J Ophthalmol 18(1):150–154PubMed
53.
Davis JL, Serfass MS, Lai MY, Trask DK, Azen SP (1995) Silicone oil in repair of retinal detachments caused by necrotizing retinitis in HIV infection. Arch Ophthalmol 113:1401–1409PubMed
54.
Peyman GA, Smith RT (1987) Use of fluorosilicone to unfold a giant retinal tear. Int Ophthalmol 10(3):149–151CrossRefPubMed
55.
Chang S, Ozmert E, Zimmerman NJ (1988) Intraoperativeperfluorocarbon liquids in the management of proliferative vitreoretinopathy. Am J Ophthalmol 106(6):668–674PubMed
56.
Meinert H, Roy T (2000) Semifluorinated alkanes a new class of compounds with outstanding properties for use in ophthalmology. Eur J Ophthalmol 10(3):189–197PubMed
57.
Rizzo S, Genovesi-Ebert F, Vento A, Cresti F, Di Bartolo E, Belting C (2007) A new heavy silicone oil (HWS 46–3000) used as a prolonged internal tamponade agent in complicated vitreoretinal surgery: a pilot study. Retina 27(5):613–620CrossRefPubMed
58.
Rizzo S, Belting C, Genovesi-Ebert F, Cresti F, Vento A, Martini R (2006) Successful treatment of persistent macular holes using ‘heavy silicone oil’ as intraocular tamponade. Retina 26(8):905–908CrossRefPubMed
59.
Wolf S, Schon V, Meier P, Wiedemann P (2003) Silicone oil–RMN3 mixture (‘heavy silicone oil’) as internal tamponade for complicated retinal detachment. Retina 23(3):335–342CrossRefPubMed
60.
Theelen T, Tilanus MA, Klevering BJ (2004) Intraocular inflammation following endotamponade with high-density silicone oil. Graefes Arch Clin Exp Ophthalmol 242(7):617–620CrossRefPubMed
61.
Wong D, Van Meurs JC, Stappler T, Groenewald C, PearceI A, McGalliard JN (2005) A pilot study on the use of aperfluorohexyloctane/silicone oil solution as a heavier than water internal tamponade agent. Br J Ophthalmol 89(6):662–665CrossRefPubMed
62.
Sandner D, Engelmann K (2005) First experiences with highdensity silicone oil (Densiron) as an intraocular tamponade in complex retinal detachment. Graefes Arch Clin Exp Ophthalmol 5:1–11
63.
Tognetto D, Minutola D, Sanguinetti G, Ravalico G (2005) Anatomical and functional outcomes after heavy silicone oil tamponade in vitreoretinal surgery for complicated retinal detachment: a pilot study. Ophthalmology 112(9):1574CrossRefPubMed
64.
Rizzo S, Genovesi-Ebert F, Belting C, Vento A, Cresti F (2005) A pilot study on the use of silicone oil–RMN3 as heavier than water endotamponade agent. Graefes Arch Clin Exp Ophthalmol 243(11):1153–1157CrossRefPubMed
65.
Cheung BT, Lai TY, Yuen CY, Lai WW, Tsang CW, Lam DS (2007) Results of high-density silicone oil as a tamponade agent in macular hole retinal detachment in patients with high myopia. Br J Ophthalmol 91(6):719–721CrossRefPubMed
66.
Joussen AM, Wong D (2008) The concept of heavy tamponades—chances and limitations. Graefes Arch Clin Exp Ophthalmol 246(9):1217–1224CrossRefPubMed
67.
Gonvers M, Andenmatten R (1996) Temporary silicone oil tamponade and intraocular pressure: an 11-year retrospective study. Eur J Ophthalmol 6:74–80PubMed
68.
Gonvers M (1982) Temporary use of intraocular silicone oil in the treatment of detachment with massive periretinal proliferation. Ophthalmologica 184:210–218PubMedCrossRef
69.
Leaver PK, Cooling RJ, Feretis EB, Lean JS, Mcleod D (1984) Vitrectomy and fluid/silicone-oil exchange for giant retinal tears: results at six months. Br J Ophthalmol 68:432–8CrossRef
70.
Ober RR, Blanks JC, Ogden TE, Pickford M, Minkler DS, Ryan SJ (1983) Experimental retinal tolerance to liquid silicone. Retina 3:77–85CrossRefPubMed
71.
Cairns JD, Anand N (1984) Combined vitrectomy, intraocular microsurgery and liquid silicone in the treatment of proliferative vitreo-retinopathy. Aust J Ophthalmol 12:133–138CrossRefPubMed
72.
Leaver PK, Grey RHB, Garner A (1979) Complications following silicone oil injection. Mod Probl Ophthalmol 20: 290–294
73.
Al-Jazzaf AM, Netland PA, Charles S (2005) Incidence and management of elevated intraocular pressure after silicone oil injection. J Glaucoma 14(1):40–46CrossRefPubMed
74.
Bartov E, Huna R, Ashkenazi I et al (1991) Identification, prevention and treatment of silicone oil pupillary block after an inferior iridectomy. Am J Ophthalmol 111:501–504PubMed
75.
Beekhuis WH, Ando F, Zivojnovic R, Meterns DAE, Peperkamp E (1987) Basal iridectomy at 6 o’clock in the aphakic eye treated with silicone oil: prevention of keratopathy and secondary glaucoma. Br J Ophthalmol 71(3):197–200CrossRefPubMed
76.
Madreperla SA, McCuen BW (1995) Inferior peripheral iridectomy in patients receiving silicone oil. Rates of postoperative closure and effect on oil position. Retina 15:87–90CrossRefPubMed
77.
Elliott A, Bacon A, Scott J (1990) The superior peripheral iridectomy: prevention of pupil block due to silicone oil. Eye 4:226–229PubMed
78.
79.
Reddy MA, Aylward GW (1995) The efficacy of Nd:YAG laser iridotomy in the treatment of closed peripheral iridotomies in silicone-oil-filled aphakic eyes. Eye 9(pt 6):757–759PubMed
80.
Zalta AH, Boyle NS, Zalta AK (2007) Silicone oil pupillary block: an exception to combined argon-Nd:YAG laser iridotomy success in angle-closure glaucoma. Arch Ophthalmol 125(7):883–888CrossRefPubMed
81.
Jackson TL, Thiagarajan M, Murthy R, Snead MP, Wong D, Williamson TH (2001) Pupil block glaucoma in phakic and pseudophakic patients after vitrectomy withsilicone oil injection. Am J Ophthalmol 132(3):414–416CrossRefPubMed
82.
Bloom PA, Tsai JC, Sharma K et al (1997) “Cyclodiode”. Transcleral diode laser cyclophotocoagulation in the treatment of advanced refractory glaucoma. Ophthalmology 104:1508–1519PubMed
83.
Han SK, Park KH, Kim DM et al (1999) Effect of diode laser trans-scleral cyclophotocoagulation in the management of glaucoma after intravitreal silicone injection for complicated retinal detachments. Br J Ophthalmol 83:713–717CrossRefPubMed
84.
Ghazi-Nouri SM, Vakalis AN, Bloom PA, Bunce C, Charteris DG (2005) Long-term results of the management of silicone oil-induced raised intraocular pressure by diode laser cycloablation. Eye 19(7):765–769CrossRefPubMed
85.
Sivagnanavel V, Ortiz-Hurtado A, Williamson TH (2005) Diode laser trans-scleral cyclophotocoagulation in the management of glaucoma in patients with long-term intravitreal silicone oil. Eye. 19(3):253–257CrossRefPubMed
86.
Suzuki Y, Araie M, Yumita A, Yamamoto T (1991) Transscleral Nd: YAG laser cyclophotocoagulation versus cyclocryotherapy. Graefes Arch Clin Exp Ophthalmol 229:33–36CrossRefPubMed
87.
Lam S, Tessler HH, Lam BL, Wilensky JT (1992) High incidence of sympathetic ophthalmia after contact and noncontact neodymium:YAG cyclotherapy. Ophthalmology 99:1818–1822PubMed
88.
Pastor S (2001) Cyclophotocoagulation: A report by the American Academy of Ophthalmology. Ophthalmology 108(11):2130–2138CrossRefPubMed
89.
Flaxel CJ, Mitchell SM, Aylward GW (2000) Visual outcome after silicone oil removal and recurrent retinal detachment repair. Eye 14:834–838PubMed
90.
Moisseiev J, Barak A, Manaim T, Treister G (1993) Removal of silicone oil in the management of glaucoma in eyes with emulsified silicone. Retina 13:290–295CrossRefPubMed
91.
Li SY, Wang WJ, Chen QY (2001) The change of intraocular pressure after silicone oil removal. Chin J Ocul Fundus Dis 17:61–63
92.
Senn P, Buchi E, Daicker B, Schipper I (1994) Bubbles in the bleb—troubles in the bleb? Molteno implant and intraocular tamponade with silicone oil in an aphakic patient. Ophthalmic Surg 25:379–382PubMed
Metadaten
Titel
Silicone oil induced glaucoma: A review
verfasst von
Parul Ichhpujani
Anjana Jindal
L. Jay Katz
Publikationsdatum
01.12.2009
Verlag
Springer-Verlag
Erschienen in
Graefe's Archive for Clinical and Experimental Ophthalmology / Ausgabe 12/2009
Print ISSN: 0721-832X
Elektronische ISSN: 1435-702X
DOI
https://doi.org/10.1007/s00417-009-1155-x

Weitere Artikel der Ausgabe 12/2009

Graefe's Archive for Clinical and Experimental Ophthalmology 12/2009 Zur Ausgabe

Retinal Disorders

Intravitreal ranibizumab (Lucentis) for treatment of central retinal vein occlusion: a prospective study

Acknowledgement

Acknowledgement to reviewers 2009

Medical Ophthalmology

Diffusion characteristics of vitreous humour and saline solution follow the Stokes Einstein equation

Letter to the Editor

A myth of ophthalmic beta-blockers therapy

Letter to the Editor

Response to: A myth of ophthalmic beta-blockers therapy

Basic Science

Myocilin in the trabecular meshwork of eyes with primary open-angle glaucoma

Neu im Fachgebiet Augenheilkunde

08.04.2024 | Therapieverfahren in der Augenheilkunde | CME

Ophthalmika in der Schwangerschaft

08.03.2024 | Vitrektomie | Originalien

Operative Therapie und Keimnachweis bei endogener Endophthalmitis
Datenauswertung aus 5 Augenkliniken

04.03.2024 | Vitrektomie | Leitthema

Bakterielle endogene Endophthalmitis
Erregerspektrum und medikamentöse Therapie

27.02.2024 | Erkrankungen der Hornhaut | CME

So erreichen Sie eine bestmögliche Wundheilung der Kornea

Update Augenheilkunde

Bestellen Sie unseren Fach-Newsletter und bleiben Sie gut informiert.

Newsletter bestellen