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Erschienen in: Graefe's Archive for Clinical and Experimental Ophthalmology 4/2020

09.12.2019 | Review Article

Optical coherence tomography angiography-derived flow density: a review of the influencing factors

verfasst von: Viktoria C. Brücher, Jens J. Storp, Nicole Eter, Maged Alnawaiseh

Erschienen in: Graefe's Archive for Clinical and Experimental Ophthalmology | Ausgabe 4/2020

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Abstract

Research interest in the possibility of quantifying macular and optic nerve head perfusion through optical coherence tomography angiography (OCTA) is rapidly advancing. Numerous scientific trials have furthered our understanding of the capabilities and the limitations of this novel technology, while applying OCTA to various ocular pathologies. In recent years, different parameters such as age, gender, intraocular pressure, spherical equivalent, physical activity, systemic diseases, and medication have been shown to have a significant impact on quantitative OCTA metrics. Since OCTA is likely to remain a “hot topic” in the near future, it is crucial to be aware of influencing factors in order to ensure correct interpretation of imaging results. This article reviews the factors currently known to influence flow density (FD) as measured by OCTA in healthy eyes.
Literatur
2.
Zurück zum Zitat Kim DY, Fingler J, Zawadzki RJ et al (2013) Optical imaging of the chorioretinal vasculature in the living human eye. Proc Natl Acad Sci 110:14354–14359CrossRefPubMedPubMedCentral Kim DY, Fingler J, Zawadzki RJ et al (2013) Optical imaging of the chorioretinal vasculature in the living human eye. Proc Natl Acad Sci 110:14354–14359CrossRefPubMedPubMedCentral
13.
Zurück zum Zitat Müller VC, Storp JJ, Kerschke L, Nelis P, Eter N, Alnawaiseh M (2019) Diurnal variations in flow density measured using optical coherence tomography angiography and the impact of heart rate, mean arterial pressure and intraocular pressure on flow density in primary open-angle glaucoma patients. Acta Ophthalmol. https://doi.org/10.1111/aos.14089 Müller VC, Storp JJ, Kerschke L, Nelis P, Eter N, Alnawaiseh M (2019) Diurnal variations in flow density measured using optical coherence tomography angiography and the impact of heart rate, mean arterial pressure and intraocular pressure on flow density in primary open-angle glaucoma patients. Acta Ophthalmol. https://​doi.​org/​10.​1111/​aos.​14089
15.
Zurück zum Zitat Coscas F, Sellam A, Glacet-Bernard A, Jung C, Goudot M, Miere A, Souied EH (2016) Normative data for vascular density in superficial and deep capillary plexuses of healthy adults assessed by optical coherence tomography angiography. Invest Ophthalmol Vis Sci 57(9):OCT211–OCT223. https://doi.org/10.1167/iovs.15-18793CrossRefPubMed Coscas F, Sellam A, Glacet-Bernard A, Jung C, Goudot M, Miere A, Souied EH (2016) Normative data for vascular density in superficial and deep capillary plexuses of healthy adults assessed by optical coherence tomography angiography. Invest Ophthalmol Vis Sci 57(9):OCT211–OCT223. https://​doi.​org/​10.​1167/​iovs.​15-18793CrossRefPubMed
36.
Zurück zum Zitat Bennett AG, Rudnicka AR, Edgar DF (1994) Improvements on Littmann’s method of determining the size of retinal features by fundus photography. Graefes Arch Clin Exp Ophthalmol 232:361–367CrossRefPubMed Bennett AG, Rudnicka AR, Edgar DF (1994) Improvements on Littmann’s method of determining the size of retinal features by fundus photography. Graefes Arch Clin Exp Ophthalmol 232:361–367CrossRefPubMed
57.
Zurück zum Zitat Ravalico G, Toffoli G, Pastori G, Crocè M, Calderini S (1996) Age-related ocular blood flow changes. Invest Ophthalmol Vis Sci 37(13):2645–2650PubMed Ravalico G, Toffoli G, Pastori G, Crocè M, Calderini S (1996) Age-related ocular blood flow changes. Invest Ophthalmol Vis Sci 37(13):2645–2650PubMed
102.
Metadaten
Titel
Optical coherence tomography angiography-derived flow density: a review of the influencing factors
verfasst von
Viktoria C. Brücher
Jens J. Storp
Nicole Eter
Maged Alnawaiseh
Publikationsdatum
09.12.2019
Verlag
Springer Berlin Heidelberg
Erschienen in
Graefe's Archive for Clinical and Experimental Ophthalmology / Ausgabe 4/2020
Print ISSN: 0721-832X
Elektronische ISSN: 1435-702X
DOI
https://doi.org/10.1007/s00417-019-04553-2

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