Skip to main content
Erschienen in: Graefe's Archive for Clinical and Experimental Ophthalmology 9/2021

12.03.2021 | Retinal Disorders

Workup following retinal artery occlusion—experience from an outpatient retina clinic and the delay in workup

verfasst von: Gautam Vangipuram, Louise Yang, M. Parker Weigle, Barton L. Blackorby, Kevin J. Blinder, Sabin Dang, Gaurav K. Shah

Erschienen in: Graefe's Archive for Clinical and Experimental Ophthalmology | Ausgabe 9/2021

Einloggen, um Zugang zu erhalten

Abstract

Purpose

Acute retinal artery occlusion (RAO) is an urgent ophthalmic condition often indicative of future ischemic pathology. Patients diagnosed at an outpatient retina clinic must present to an emergency department (ED) or primary care clinic to obtain a systemic workup. We review the overall compliance and suspected delay in completing the required testing.

Design

Retrospective cohort study

Methods

Patients presenting with a symptomatic RAO from June 2009 to January 2019 at a vitreoretinal practice (The Retina Institute, St. Louis, MO) were included. Documentation of carotid vasculature and echocardiographic imaging was requested from the patient’s primary care physician (PCP), cardiologist, or neurologist. Time to workup (TTW) from RAO diagnosis to receiving appropriate workup and site of workup (ED vs. outpatient setting) were recorded.

Results

One hundred forty-seven patients were included. A total of 132 (89.8%) patients were documented as having completed at least one type of cardiovascular or carotid imaging. Seventy-seven patients (52.3%) were documented to have completed both carotid and echocardiographic imaging. Following RAO diagnosis, 97 (66.0%) patients were referred to an outpatient facility while 35 (23.8%) were evaluated at an ED. Mean TTW through an ED setting vs. outpatient was 2.20 days (1.10 STDM, range 0–29) vs.13.6 days (2.23 STDM, range 0–149) respectively (p=0.003).

Conclusion

Our study gives objective data to the delay suspected in referring patients with acute symptomatic RAO for outpatient workup. We recommend all outpatient ophthalmology and retina practices establish a relationship with a comprehensive or primary stroke center to facilitate urgent testing through an emergency department.
Literatur
1.
Zurück zum Zitat Lee J, Kim SW, Lee SC (2014) Co-occurrence of acute retinal artery occlusion and acute ischemic stroke: diffusion-weighted magnetic resonance imaging study. Am J Ophthalmol 157:1231–1238CrossRef Lee J, Kim SW, Lee SC (2014) Co-occurrence of acute retinal artery occlusion and acute ischemic stroke: diffusion-weighted magnetic resonance imaging study. Am J Ophthalmol 157:1231–1238CrossRef
2.
Zurück zum Zitat Avery MB, Magal I, Kherani A, Mitha AP (2019) Risk of stroke in patients with ocular arterial occlusive disorders: a retrospective Canadian study. J Am Heart Assoc 8(3):e010509CrossRef Avery MB, Magal I, Kherani A, Mitha AP (2019) Risk of stroke in patients with ocular arterial occlusive disorders: a retrospective Canadian study. J Am Heart Assoc 8(3):e010509CrossRef
3.
Zurück zum Zitat Chang YS, Chu CC, Weng SF (2015) The risk of acute coronary syndrome after retinal artery occlusion: a population-based cohort study. Br J Ophthalmol 99:227–231CrossRef Chang YS, Chu CC, Weng SF (2015) The risk of acute coronary syndrome after retinal artery occlusion: a population-based cohort study. Br J Ophthalmol 99:227–231CrossRef
4.
Zurück zum Zitat Brown GC, Magargal LE (1982) Central retinal artery obstruction and visual acuity. Ophthalmology 89:14–19CrossRef Brown GC, Magargal LE (1982) Central retinal artery obstruction and visual acuity. Ophthalmology 89:14–19CrossRef
5.
Zurück zum Zitat Brown GC, Shields JA (1979) Cilioretinal arteries and retinal arterial occlusion. Arch Ophthalmol 97:84–92CrossRef Brown GC, Shields JA (1979) Cilioretinal arteries and retinal arterial occlusion. Arch Ophthalmol 97:84–92CrossRef
6.
Zurück zum Zitat Hayreh SS, Zimmerman MB (2005) Central retinal artery occlusion: visual outcome. Am J Ophthalmol 140:376–391CrossRef Hayreh SS, Zimmerman MB (2005) Central retinal artery occlusion: visual outcome. Am J Ophthalmol 140:376–391CrossRef
7.
Zurück zum Zitat Leavitt JA, Larson TA, Hodge DO, Gullerud RE (2011) The incidence of central retinal artery occlusion in Olmsted County, Minnesota. Am J Ophthalmol 152:820–823CrossRef Leavitt JA, Larson TA, Hodge DO, Gullerud RE (2011) The incidence of central retinal artery occlusion in Olmsted County, Minnesota. Am J Ophthalmol 152:820–823CrossRef
8.
Zurück zum Zitat Park SJ, Choi NK, Yang BR (2015) Risk and risk periods for stroke and acute myocardial infarction in patients with central retinal artery occlusion. Ophthalmology 122:2336–2343CrossRef Park SJ, Choi NK, Yang BR (2015) Risk and risk periods for stroke and acute myocardial infarction in patients with central retinal artery occlusion. Ophthalmology 122:2336–2343CrossRef
9.
Zurück zum Zitat Lavin P, Patrylo M, Hollar M, Espaillat KB, Kirshner H, Schrag M (2018) Stroke risk and risk factors in patients with central retinal artery occlusion. Am J Ophthalmol 196:96–100CrossRef Lavin P, Patrylo M, Hollar M, Espaillat KB, Kirshner H, Schrag M (2018) Stroke risk and risk factors in patients with central retinal artery occlusion. Am J Ophthalmol 196:96–100CrossRef
10.
Zurück zum Zitat Golsari A, Bittersohl D, Cheng B (2017) Silent brain infarctions and leukoaraiosis in patients with retinal ischemia: a prospective single-center observational study. Stroke 48(5):1392–1396CrossRef Golsari A, Bittersohl D, Cheng B (2017) Silent brain infarctions and leukoaraiosis in patients with retinal ischemia: a prospective single-center observational study. Stroke 48(5):1392–1396CrossRef
11.
Zurück zum Zitat Olsen TW, Pulido JS, Folk JC, Hyman L, Flaxel CJ, Adelman RA (2017) Retinal and ophthalmic artery occlusions Preferred Practice Pattern. Ophthalmology 124(2):120–143CrossRef Olsen TW, Pulido JS, Folk JC, Hyman L, Flaxel CJ, Adelman RA (2017) Retinal and ophthalmic artery occlusions Preferred Practice Pattern. Ophthalmology 124(2):120–143CrossRef
12.
Zurück zum Zitat Flaxel CJ, Adelman RA, Bailey ST (2020) Retinal and ophthalmic artery occlusions Preferred Practice Pattern. 127(2):259–287 Flaxel CJ, Adelman RA, Bailey ST (2020) Retinal and ophthalmic artery occlusions Preferred Practice Pattern. 127(2):259–287
13.
Zurück zum Zitat Chang YS, Jan RL, Weng SF (2012) Retinal artery occlusion and the 3-year risk of stroke in Taiwan: a nationwide population-based study. Am J Ophthalmol 154(4):645–652CrossRef Chang YS, Jan RL, Weng SF (2012) Retinal artery occlusion and the 3-year risk of stroke in Taiwan: a nationwide population-based study. Am J Ophthalmol 154(4):645–652CrossRef
14.
Zurück zum Zitat Rothwell PM, Giles MF, Chandratheva A (2007) Early use of Existing Preventive Strategies for Stroke (EXPRESS) study. Effect of urgent treatment of transient ischaemic attack and minor stroke on early recurrent stroke (EXPRESS study): a prospective population-based sequential comparison. Lancet 370:1432–1442CrossRef Rothwell PM, Giles MF, Chandratheva A (2007) Early use of Existing Preventive Strategies for Stroke (EXPRESS) study. Effect of urgent treatment of transient ischaemic attack and minor stroke on early recurrent stroke (EXPRESS study): a prospective population-based sequential comparison. Lancet 370:1432–1442CrossRef
15.
Zurück zum Zitat Gladstone DJ, Oh J, Fang J (2009) Urgency of carotid endarterectomy for secondary stroke prevention: results from the Registry of the Canadian Stroke Network. Stroke 40(8):2776–2782CrossRef Gladstone DJ, Oh J, Fang J (2009) Urgency of carotid endarterectomy for secondary stroke prevention: results from the Registry of the Canadian Stroke Network. Stroke 40(8):2776–2782CrossRef
16.
Zurück zum Zitat Rothwell PM, Eliasziw M, Gutnikov S (2004) Carotid Endarterectomy Trialists Collaboration. Endarterectomy for symptomatic carotid stenosis in relation to clinical subgroups and timing of surgery. Lancet 363:915–924CrossRef Rothwell PM, Eliasziw M, Gutnikov S (2004) Carotid Endarterectomy Trialists Collaboration. Endarterectomy for symptomatic carotid stenosis in relation to clinical subgroups and timing of surgery. Lancet 363:915–924CrossRef
17.
Zurück zum Zitat Schrag M, Youn T, Schindler J, Kirshner H, Greer D (2015) Intravenous fibrinolytic therapy in central retinal artery occlusion: a patient-level meta-analysis. JAMA Neurol 72(10):1148–1154CrossRef Schrag M, Youn T, Schindler J, Kirshner H, Greer D (2015) Intravenous fibrinolytic therapy in central retinal artery occlusion: a patient-level meta-analysis. JAMA Neurol 72(10):1148–1154CrossRef
18.
Zurück zum Zitat Mac Grory B, Schrag M (2020) Re: Flaxel: Retinal and ophthalmic artery occlusions Preferred Practice Pattern. Ophthalmology 127:259–287CrossRef Mac Grory B, Schrag M (2020) Re: Flaxel: Retinal and ophthalmic artery occlusions Preferred Practice Pattern. Ophthalmology 127:259–287CrossRef
19.
Zurück zum Zitat Abel AS, Suresh S, Hussein HM, Carpenter AF, Montezuma SR, Lee MS (2017) Practice patterns after acute embolic retinal artery occlusion. Asia Pac J Ophthalmol 6(1):37–39 Abel AS, Suresh S, Hussein HM, Carpenter AF, Montezuma SR, Lee MS (2017) Practice patterns after acute embolic retinal artery occlusion. Asia Pac J Ophthalmol 6(1):37–39
20.
Zurück zum Zitat Biousse V, Nahab F, Newman NJ (2018) Management of acute retinal ischemia: follow the guidelines! Ophthalmology 125(10):1597–1607CrossRef Biousse V, Nahab F, Newman NJ (2018) Management of acute retinal ischemia: follow the guidelines! Ophthalmology 125(10):1597–1607CrossRef
21.
Zurück zum Zitat Ross MA, Compton S, Medado P (2007) An emergency department diagnostic protocol for patients with transient ischemic attack: a randomized controlled trial. Ann Emerg Med 50:109–119CrossRef Ross MA, Compton S, Medado P (2007) An emergency department diagnostic protocol for patients with transient ischemic attack: a randomized controlled trial. Ann Emerg Med 50:109–119CrossRef
22.
Zurück zum Zitat Nahab F, Leach G, Kingston C (2012) Impact of an emergency department observation unit transient ischemic attack protocol on length of stay and cost. J Stroke Cerebrovasc Dis 21(8):673–678CrossRef Nahab F, Leach G, Kingston C (2012) Impact of an emergency department observation unit transient ischemic attack protocol on length of stay and cost. J Stroke Cerebrovasc Dis 21(8):673–678CrossRef
23.
Zurück zum Zitat Lauda F, Neugebauer H, Reiber L, Jüttler E (2015) Acute silent brain infarction in monocular visual loss of ischemic origin. Cerebrovasc Dis 40:151–156CrossRef Lauda F, Neugebauer H, Reiber L, Jüttler E (2015) Acute silent brain infarction in monocular visual loss of ischemic origin. Cerebrovasc Dis 40:151–156CrossRef
24.
Zurück zum Zitat Cho KH, Kim CK, Woo SJ (2016) Cerebral small vessel disease in branch retinal artery occlusion. Invest Ophthalmol Vis Sci 57:5818–5824CrossRef Cho KH, Kim CK, Woo SJ (2016) Cerebral small vessel disease in branch retinal artery occlusion. Invest Ophthalmol Vis Sci 57:5818–5824CrossRef
25.
Zurück zum Zitat Tanaka K, Uehara T, Kimura K, Japan TIA Research Group 2009-2011 (2014) Features of patients with transient monocular blindness: a multicenter retrospective study in Japan. J Stroke Cerebrovasc Dis 4(23):151–155CrossRef Tanaka K, Uehara T, Kimura K, Japan TIA Research Group 2009-2011 (2014) Features of patients with transient monocular blindness: a multicenter retrospective study in Japan. J Stroke Cerebrovasc Dis 4(23):151–155CrossRef
Metadaten
Titel
Workup following retinal artery occlusion—experience from an outpatient retina clinic and the delay in workup
verfasst von
Gautam Vangipuram
Louise Yang
M. Parker Weigle
Barton L. Blackorby
Kevin J. Blinder
Sabin Dang
Gaurav K. Shah
Publikationsdatum
12.03.2021
Verlag
Springer Berlin Heidelberg
Erschienen in
Graefe's Archive for Clinical and Experimental Ophthalmology / Ausgabe 9/2021
Print ISSN: 0721-832X
Elektronische ISSN: 1435-702X
DOI
https://doi.org/10.1007/s00417-021-05135-x

Weitere Artikel der Ausgabe 9/2021

Graefe's Archive for Clinical and Experimental Ophthalmology 9/2021 Zur Ausgabe

Neu im Fachgebiet Augenheilkunde

Update Augenheilkunde

Bestellen Sie unseren Fach-Newsletter und bleiben Sie gut informiert.