Skip to main content
Erschienen in: Langenbeck's Archives of Surgery 2/2019

27.02.2019 | How-I-Do-It article

Left kidney mobilization technique during radical antegrade modular pancreatosplenectomy (RAMPS)

verfasst von: Genki Watanabe, Hiromichi Ito, Takafumi Sato, Yoshihiro Ono, Yoshihiro Mise, Yosuke Inoue, Yu Takahashi, Akio Saiura

Erschienen in: Langenbeck's Archives of Surgery | Ausgabe 2/2019

Einloggen, um Zugang zu erhalten

Abstract

Purpose

Radical antegrade modular pancreatosplenectomy (RAMPS) has been accepted as a standard operation for distal pancreatic cancer. While enbloc retroperitoneal dissection in the “medial to lateral” direction is one of the most important steps in this oncologic procedure, it is technically challenging due to the depth of organs under the left costal margin, and poor exposure of the resecting organs in this area will increase the risk of incomplete oncologic dissection.

Methods

To improve exposure of the left upper quadrant organs, left kidney was completely mobilized during RAMPS, and all the left upper quadrant organs were elevated and medialized by lap sponges packed in the retro-renal space. The operative and oncologic outcomes for patients who underwent our modified RAMPS with left kidney mobilization were evaluated.

Results

One hundred and forty-four patients with distal pancreatic cancer underwent this procedure from 2005 through 2016. The median operation time was 310 min (range, 132–899), and blood loss was 440 ml (25–2430). There was no complication associated to left kidney mobilization. The median number of harvested lymph nodes was 27 (3–87). While 77% of the tumors had microscopic retroperitoneal invasion, 96% of patients achieved negative retroperitoneal margin.

Conclusions

Left kidney mobilization is useful for safe and oncologically sound lateral retroperitoneal dissection during RAMPS for distal pancreatic cancer.
Anhänge
Nur mit Berechtigung zugänglich
Literatur
1.
Zurück zum Zitat Strasberg SM, Drebin JA, Linehan D (2003) Radical antegrade modular pancreatosplenectomy. Surgery 133:521–527CrossRefPubMed Strasberg SM, Drebin JA, Linehan D (2003) Radical antegrade modular pancreatosplenectomy. Surgery 133:521–527CrossRefPubMed
2.
Zurück zum Zitat Trede M, Carter DC (1997) Left hemopancreatectomy. In: Surgery of the pancreas, 2nd edn. Churchill Livingstone, UK, pp 517–520 Trede M, Carter DC (1997) Left hemopancreatectomy. In: Surgery of the pancreas, 2nd edn. Churchill Livingstone, UK, pp 517–520
3.
Zurück zum Zitat Von Hoff DD, Evans DB, Hruban RH (2005) Distal pancreatectomy. In: Pancreatic cancer, Jones and Bartlett Publishers pp 299–311 Von Hoff DD, Evans DB, Hruban RH (2005) Distal pancreatectomy. In: Pancreatic cancer, Jones and Bartlett Publishers pp 299–311
4.
Zurück zum Zitat Lillemoe KD, Kaushal S, Cameron JL, Sohn TA, Pitt HA, Yeo CJ (1999) Distal pancreatectomy: indications and outcomes in 235 patients. Ann Surg 229:693–700CrossRefPubMedPubMedCentral Lillemoe KD, Kaushal S, Cameron JL, Sohn TA, Pitt HA, Yeo CJ (1999) Distal pancreatectomy: indications and outcomes in 235 patients. Ann Surg 229:693–700CrossRefPubMedPubMedCentral
5.
Zurück zum Zitat Ozaki H, Kinoshita T, Kosuge T, Yamamoto J, Shimada K, Inoue K, Koyama Y, Mukai K (1996) An aggressive therapeutic approach to carcinoma of the body and tail of the pancreas. Cancer 77:2240–2245CrossRefPubMed Ozaki H, Kinoshita T, Kosuge T, Yamamoto J, Shimada K, Inoue K, Koyama Y, Mukai K (1996) An aggressive therapeutic approach to carcinoma of the body and tail of the pancreas. Cancer 77:2240–2245CrossRefPubMed
6.
Zurück zum Zitat Strasberg SM, Linehan DC, Hawkins WG (2007) Radical antegrade modular pancreatosplenectomy procedure for adenocarcinoma of the body and tail of the pancreas: ability to obtain negative tangential margins. J Am Coll Surg 204:244–249CrossRefPubMed Strasberg SM, Linehan DC, Hawkins WG (2007) Radical antegrade modular pancreatosplenectomy procedure for adenocarcinoma of the body and tail of the pancreas: ability to obtain negative tangential margins. J Am Coll Surg 204:244–249CrossRefPubMed
8.
Zurück zum Zitat Mitchem JB, Hamilton N, Gao F, Hawkins WG, Linehan DC, Strasberg SM (2012) Long-term results of resection of adenocarcinoma of the body and tail of the pancreas using radical antegrade modular pancreatosplenectomy procedure. J Am Coll Surg 214:46–52CrossRefPubMed Mitchem JB, Hamilton N, Gao F, Hawkins WG, Linehan DC, Strasberg SM (2012) Long-term results of resection of adenocarcinoma of the body and tail of the pancreas using radical antegrade modular pancreatosplenectomy procedure. J Am Coll Surg 214:46–52CrossRefPubMed
9.
Zurück zum Zitat Grossman JG, Fields RC, Hawkins WG, Strasberg SM (2016) Single institution results of radical antegrade modular pancreatosplenectomy for adenocarcinoma of the body and tail of pancreas in 78 patients. J Hepatobiliary Pancreat Sci 23:432–441CrossRefPubMed Grossman JG, Fields RC, Hawkins WG, Strasberg SM (2016) Single institution results of radical antegrade modular pancreatosplenectomy for adenocarcinoma of the body and tail of pancreas in 78 patients. J Hepatobiliary Pancreat Sci 23:432–441CrossRefPubMed
10.
Zurück zum Zitat Shoup M, Conlon KC, Klimstra D, Brennan MF (2003) Is extended resection for adenocarcinoma of the body or tail of the pancreas justified? J Gastrointest Surg 7:946–952CrossRefPubMed Shoup M, Conlon KC, Klimstra D, Brennan MF (2003) Is extended resection for adenocarcinoma of the body or tail of the pancreas justified? J Gastrointest Surg 7:946–952CrossRefPubMed
11.
Zurück zum Zitat Christein JD, Kendrick ML, Iqbal CW, Nagorney DM, Farnell MB (2005) Distal pancreatectomy for resectable adenocarcinoma of the body and tail of the pancreas. J Gastrointest Surg 9:922–927CrossRefPubMed Christein JD, Kendrick ML, Iqbal CW, Nagorney DM, Farnell MB (2005) Distal pancreatectomy for resectable adenocarcinoma of the body and tail of the pancreas. J Gastrointest Surg 9:922–927CrossRefPubMed
12.
Zurück zum Zitat Shimada K, Sakamoto Y, Sano T, Kosuge T (2006) Prognostic factors after distal pancreatectomy with extended lymphadenectomy for invasive pancreatic adenocarcinoma of the body and tail. Surgery 139:288–295CrossRefPubMed Shimada K, Sakamoto Y, Sano T, Kosuge T (2006) Prognostic factors after distal pancreatectomy with extended lymphadenectomy for invasive pancreatic adenocarcinoma of the body and tail. Surgery 139:288–295CrossRefPubMed
13.
Zurück zum Zitat Park HJ, Do You D, Choi DW, Heo JS, Choi SH (2014) Role of radical antegrade modular pancreatosplenectomy for adenocarcinoma of the body and tail of the pancreas. World J Surg 38:186–193CrossRefPubMed Park HJ, Do You D, Choi DW, Heo JS, Choi SH (2014) Role of radical antegrade modular pancreatosplenectomy for adenocarcinoma of the body and tail of the pancreas. World J Surg 38:186–193CrossRefPubMed
14.
Zurück zum Zitat de Rooij T, Tol JA, van Eijck CH et al (2016) Outcomes of distal pancreatectomy for pancreatic ductal adenocarcinoma in the Netherlands: a nationwide retrospective analysis. Ann Surg Oncol 23:585–591CrossRefPubMed de Rooij T, Tol JA, van Eijck CH et al (2016) Outcomes of distal pancreatectomy for pancreatic ductal adenocarcinoma in the Netherlands: a nationwide retrospective analysis. Ann Surg Oncol 23:585–591CrossRefPubMed
15.
Zurück zum Zitat Abe T, Ohuchida K, Miyasaka Y, Ohtsuka T, Oda Y, Nakamura M (2016) Comparison of surgical outcomes between radical antegrade modular pancreatosplenectomy (RAMPS) and standard retrograde pancreatosplenectomy (SPRS) for left-sided pancreatic cancer. World J Surg 40:2267–2275CrossRefPubMed Abe T, Ohuchida K, Miyasaka Y, Ohtsuka T, Oda Y, Nakamura M (2016) Comparison of surgical outcomes between radical antegrade modular pancreatosplenectomy (RAMPS) and standard retrograde pancreatosplenectomy (SPRS) for left-sided pancreatic cancer. World J Surg 40:2267–2275CrossRefPubMed
16.
Zurück zum Zitat Kajitani T (1992) Surgical atlas of the gastrointestinal tract cancer. Kanehara & Co., Ltd, Tokyo, pp 86–87 Kajitani T (1992) Surgical atlas of the gastrointestinal tract cancer. Kanehara & Co., Ltd, Tokyo, pp 86–87
17.
Zurück zum Zitat Chun YS (2018) Role of radical antegrade modular pancreatosplenectomy (RAMPS) and pancreatic cancer. Ann Surg Oncol 25:46–50CrossRefPubMed Chun YS (2018) Role of radical antegrade modular pancreatosplenectomy (RAMPS) and pancreatic cancer. Ann Surg Oncol 25:46–50CrossRefPubMed
18.
Zurück zum Zitat Zhou Y, Shi B, Wu L, Si X (2017) A systematic review of radical antegrade modular pancreatosplenectomy for adenocarcinoma of the body and tail of the pancreas. HPB 19:10–15CrossRefPubMed Zhou Y, Shi B, Wu L, Si X (2017) A systematic review of radical antegrade modular pancreatosplenectomy for adenocarcinoma of the body and tail of the pancreas. HPB 19:10–15CrossRefPubMed
19.
Zurück zum Zitat Mavros MN, Xu L, Maqsood H, Gani F, Ejaz A, Spolverato G, Al-Refaie WB, Frank SM, Pawlik TM (2015) Perioperative blood transfusion and the prognosis of pancreatic cancer surgery: systematic review and meta-analysis. Ann Surg Oncol 22:4382–4391CrossRef Mavros MN, Xu L, Maqsood H, Gani F, Ejaz A, Spolverato G, Al-Refaie WB, Frank SM, Pawlik TM (2015) Perioperative blood transfusion and the prognosis of pancreatic cancer surgery: systematic review and meta-analysis. Ann Surg Oncol 22:4382–4391CrossRef
Metadaten
Titel
Left kidney mobilization technique during radical antegrade modular pancreatosplenectomy (RAMPS)
verfasst von
Genki Watanabe
Hiromichi Ito
Takafumi Sato
Yoshihiro Ono
Yoshihiro Mise
Yosuke Inoue
Yu Takahashi
Akio Saiura
Publikationsdatum
27.02.2019
Verlag
Springer Berlin Heidelberg
Erschienen in
Langenbeck's Archives of Surgery / Ausgabe 2/2019
Print ISSN: 1435-2443
Elektronische ISSN: 1435-2451
DOI
https://doi.org/10.1007/s00423-019-01767-0

Weitere Artikel der Ausgabe 2/2019

Langenbeck's Archives of Surgery 2/2019 Zur Ausgabe

Update Chirurgie

Bestellen Sie unseren Fach-Newsletter und bleiben Sie gut informiert.

S3-Leitlinie „Diagnostik und Therapie des Karpaltunnelsyndroms“

Karpaltunnelsyndrom BDC Leitlinien Webinare
CME: 2 Punkte

Das Karpaltunnelsyndrom ist die häufigste Kompressionsneuropathie peripherer Nerven. Obwohl die Anamnese mit dem nächtlichen Einschlafen der Hand (Brachialgia parästhetica nocturna) sehr typisch ist, ist eine klinisch-neurologische Untersuchung und Elektroneurografie in manchen Fällen auch eine Neurosonografie erforderlich. Im Anfangsstadium sind konservative Maßnahmen (Handgelenksschiene, Ergotherapie) empfehlenswert. Bei nicht Ansprechen der konservativen Therapie oder Auftreten von neurologischen Ausfällen ist eine Dekompression des N. medianus am Karpaltunnel indiziert.

Prof. Dr. med. Gregor Antoniadis
Berufsverband der Deutschen Chirurgie e.V.

S2e-Leitlinie „Distale Radiusfraktur“

Radiusfraktur BDC Leitlinien Webinare
CME: 2 Punkte

Das Webinar beschäftigt sich mit Fragen und Antworten zu Diagnostik und Klassifikation sowie Möglichkeiten des Ausschlusses von Zusatzverletzungen. Die Referenten erläutern, welche Frakturen konservativ behandelt werden können und wie. Das Webinar beantwortet die Frage nach aktuellen operativen Therapiekonzepten: Welcher Zugang, welches Osteosynthesematerial? Auf was muss bei der Nachbehandlung der distalen Radiusfraktur geachtet werden?

PD Dr. med. Oliver Pieske
Dr. med. Benjamin Meyknecht
Berufsverband der Deutschen Chirurgie e.V.

S1-Leitlinie „Empfehlungen zur Therapie der akuten Appendizitis bei Erwachsenen“

Appendizitis BDC Leitlinien Webinare
CME: 2 Punkte

Inhalte des Webinars zur S1-Leitlinie „Empfehlungen zur Therapie der akuten Appendizitis bei Erwachsenen“ sind die Darstellung des Projektes und des Erstellungswegs zur S1-Leitlinie, die Erläuterung der klinischen Relevanz der Klassifikation EAES 2015, die wissenschaftliche Begründung der wichtigsten Empfehlungen und die Darstellung stadiengerechter Therapieoptionen.

Dr. med. Mihailo Andric
Berufsverband der Deutschen Chirurgie e.V.