Erschienen in:
01.05.2004 | Letter to the Editor
Osteoclastogenesis in human breast carcinoma
verfasst von:
Makoto Sano, Kentaro Kikuchi, Chen Zhao, Michiyo Kobayashi, Yoko Nakanishi, Norimichi Nemoto
Erschienen in:
Virchows Archiv
|
Ausgabe 5/2004
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Excerpt
Dear Sir, We herein report the involvement of vascular endothelial growth factor (VEGF) expression and osteoclast-like giant cell (OGC) formation in human breast carcinoma. We believe that OGCs are osteoclasts derived from peripheral blood macrophages, while overexpression of VEGF in the carcinoma cells may play a pivotal role in the osteoclastogenesis. …