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Medical Microbiology and Immunology

Erschienen in:

01.12.2007 | Review

The threat of avian influenza A (H5N1). Part IV: development of vaccines

verfasst von: Jindrich Cinatl jr, Martin Michaelis, Hans W. Doerr

Erschienen in: Medical Microbiology and Immunology | Ausgabe 4/2007

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Abstract

Among emerging and re-emerging infectious diseases, influenza constitutes one of the major threats to mankind. In this review series epidemiologic, virologic and pathologic concerns raised by infections of humans with avian influenza virus A/H5N1 are discussed. This fourth part focuses on vaccine development. Several phase I clinical studies with vaccines against H5 viruses have demonstrated limited efficacy compared to seasonal influenza vaccines. To induce protective immunity two immunisations with increased amounts of H5N1 vaccine were required. Novel vaccination strategies that are egg- and adjuvant-independent, broadly cross-reactive and long-lasting are highly desirable.

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Titel: The threat of avian influenza A (H5N1). Part IV: development of vaccines
verfasst von: Jindrich Cinatl jr
Martin Michaelis
Hans W. Doerr
Publikationsdatum: 01.12.2007
Verlag: Springer-Verlag
Erschienen in: Medical Microbiology and Immunology / Ausgabe 4/2007
Print ISSN: 0300-8584
Elektronische ISSN: 1432-1831
DOI: https://doi.org/10.1007/s00430-007-0052-3

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Sind Betablocker auch für ältere herzschwache Personen nützlich?

Kein Abstrich bei chronischen Wunden ohne Entzündungszeichen!

Manche Gestagene können das Risiko für Meningeome erhöhen

Stillende Frauen haben geringeres kardiovaskuläres Risiko

Update Innere Medizin