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Erschienen in: European Journal of Pediatrics 10/2018

19.07.2018 | Original Article

Prevalence of vitamin D deficiency in cord blood of newborns and the association with maternal vitamin D status

verfasst von: Kansuda Ariyawatkul, Porntita Lersbuasin

Erschienen in: European Journal of Pediatrics | Ausgabe 10/2018

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Abstract

Vitamin D deficiency is common in Southeast Asia but there are limited data in pregnant women and neonates. This study aimed to determine the prevalence of vitamin D deficiency in cord blood of newborns and the association with maternal vitamin D status. A total of 94 pregnant women and their neonates were included. Clinical data and venous maternal blood for calcium, phosphate, albumin, alkaline phosphatase, magnesium, intact parathyroid hormone (iPTH), and vitamin D (25OHD) were obtained on the day of labor. Cord blood was collected following delivery to evaluate vitamin D status of newborns. Mean serum maternal and cord blood 25OHD levels were 25.42 ± 8.07 and 14.85 ± 5.13 ng/mL. The prevalence of vitamin D deficiency (25OHD < 12 ng/mL) and insufficiency (25OHD 12–20 ng/mL) in cord blood of newborns were 20.2 and 69.1%, respectively. There was a significant correlation between maternal and cord blood vitamin D levels (r = 0.86; P < 0.001). The factors associated with cord blood vitamin D deficiency were low maternal 25OHD level and no vitamin D supplement during pregnancy.
Conclusion: There is a high prevalence of vitamin D deficiency among Thai neonates. Adequate prenatal vitamin D supplementation should be implemented as routine antenatal care.
What is Known:
Vitamin D deficiency is prevalent in Southeast Asia.
There are widespread vitamin D deficiency among Thai populations including pregnant women.
What is New:
There is a high prevalence of vitamin D deficiency among Thai neonates.
The factors associated with cord blood vitamin D deficiency are low maternal vitamin D level and no vitamin D supplement during pregnancy.
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Metadaten
Titel
Prevalence of vitamin D deficiency in cord blood of newborns and the association with maternal vitamin D status
verfasst von
Kansuda Ariyawatkul
Porntita Lersbuasin
Publikationsdatum
19.07.2018
Verlag
Springer Berlin Heidelberg
Erschienen in
European Journal of Pediatrics / Ausgabe 10/2018
Print ISSN: 0340-6199
Elektronische ISSN: 1432-1076
DOI
https://doi.org/10.1007/s00431-018-3210-2

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