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Erschienen in: Journal of Cancer Research and Clinical Oncology 1/2015

01.01.2015 | Original Article – Cancer Research

Discontinuation and non-adherence to endocrine therapy in breast cancer patients: is lack of communication the decisive factor?

verfasst von: P. Wuensch, A. Hahne, R. Haidinger, K. Meißler, B. Tenter, C. Stoll, B. Senf, J. Huebner

Erschienen in: Journal of Cancer Research and Clinical Oncology | Ausgabe 1/2015

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Abstract

Introduction

Non-adherence to anti-hormonal therapy is a major problem in gynecologic oncology. Reasons reported are side effects and lack of support. The aim of our study was an analysis of influence of experiences of patients with endocrine therapy and communication and information on this topic and their influence on adherence.

Methods

We developed a structured questionnaire which was tested in a pilot version and then programmed as online questionnaire and presented to patient members of self-help and breast cancer organizations.

Results

Patients only had received scarce information on endocrine therapy. Only 12.8 % stated that their questions were answered in detail, 43.2 % got no answers or only non-detailed answers. 76 % had side effects limiting functions of daily life. 60 % of physicians did not react on these side effects. There is a significant correlation between number and intensity of side effects and non-adherence or disruption of therapy (p = 0.029 and p < 0.01, respectively). Women who reported having received detailed answers to their questions also reported better adherence (p = 0.014).

Conclusion

In order to improve adherence, detailed information on side effects and answers in case of symptoms are most important. Physicians should not rely on presenting written information but should mainly engage in direct communication.
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Metadaten
Titel
Discontinuation and non-adherence to endocrine therapy in breast cancer patients: is lack of communication the decisive factor?
verfasst von
P. Wuensch
A. Hahne
R. Haidinger
K. Meißler
B. Tenter
C. Stoll
B. Senf
J. Huebner
Publikationsdatum
01.01.2015
Verlag
Springer Berlin Heidelberg
Erschienen in
Journal of Cancer Research and Clinical Oncology / Ausgabe 1/2015
Print ISSN: 0171-5216
Elektronische ISSN: 1432-1335
DOI
https://doi.org/10.1007/s00432-014-1779-z

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