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Erschienen in: Journal of Cancer Research and Clinical Oncology 10/2015

01.10.2015 | Review – Clinical Oncology

Height and kidney cancer risk: a meta-analysis of prospective studies

verfasst von: Sudong Liang, Gaofei Lv, Weikai Chen, Jianxin Jiang, Jingqun Wang

Erschienen in: Journal of Cancer Research and Clinical Oncology | Ausgabe 10/2015

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Abstract

Purpose

The aim of this study was to perform a meta-analysis to summarize the available evidence from prospective studies on the association between height and kidney cancer risk.

Methods

Relevant studies were identified through the MEDLINE and EMBASE databases up to July 2014, as well as through the references from the retrieved articles. Relative risks (RRs) from individual studies were pooled by using a random-effects model.

Results

A total of fourteen prospective studies of adult height and kidney cancer risk with 18,766 cases were included in the meta-analysis. Overall, per 10-cm increase in height was associated with an increased risk of kidney cancer (RR 1.23; 95 % confidence interval 1.18–1.28, I 2 = 11.8 %). Subgroup analysis showed a basically consistent result with the overall analysis. There was no evidence of publication bias.

Conclusions

High adult height was positively associated with the risk of kidney cancer in both men and women in this meta-analysis. Future prospective studies are needed to determine the generalizability of these findings to non-Caucasians.
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Metadaten
Titel
Height and kidney cancer risk: a meta-analysis of prospective studies
verfasst von
Sudong Liang
Gaofei Lv
Weikai Chen
Jianxin Jiang
Jingqun Wang
Publikationsdatum
01.10.2015
Verlag
Springer Berlin Heidelberg
Erschienen in
Journal of Cancer Research and Clinical Oncology / Ausgabe 10/2015
Print ISSN: 0171-5216
Elektronische ISSN: 1432-1335
DOI
https://doi.org/10.1007/s00432-014-1870-5

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