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Erschienen in: Surgical Endoscopy 2/2006

01.02.2006

Laparoscopic cholecystectomy in children with chronic hemolytic anemia

Is the outcome related to the timing of the procedure?

verfasst von: G. Currò, G. Iapichino, C. Lorenzini, R. Palmeri, E. Cucinotta

Erschienen in: Surgical Endoscopy | Ausgabe 2/2006

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Abstract

Background

The aim of this study was to evaluate whether the outcome in children with chronic hemolytic anemia (CHA) and cholelithiasis undergoing laparoscopic cholecystectomy (LC) is related to the operation timing.

Methods

From June 1995 to December 2004, 46 children with CHA were referred to our division of surgery for cholelithiasis. All 46 children were asymptomatic at the time of the first visit, and an elective LC was proposed to all of them before the onset of symptoms. The operation was accepted in the period of study by 24 children and refused by 22. The patients were divided into three groups (group A, asymptomatic; group B, symptomatic; and group C, emergency admitted) depending on clinical presentation and operation timing, and the respective outcomes were compared.

Results

Elective LC in asymptomatic children (group A) is safe with no major complications reported. In children who refused surgery (groups B and C), we observed four sickle cell crises, four acute cholecystitis, and two choledocholithiasis, and all these complications were related to waiting. Two sickle cell crises occurred in symptomatic children waiting for surgery during biliary colic. The risk of emergency admission in children with cholelithiasis and CHA awaiting surgery was found to be high: 28% of the children admitted in emergency after a mean of 32 months (range, 22–36). Morbidity rate and postoperative stay increased when children with hemoglobinopathies underwent emergency LC.

Conclusions

Elective LC should be the gold standard in children with CHA and asymptomatic cholelithiasis in order to prevent the potential complications of cholecystitis and choledocholithiasis, which lead to major risks, discomfort, and longer hospital stay.
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Metadaten
Titel
Laparoscopic cholecystectomy in children with chronic hemolytic anemia
Is the outcome related to the timing of the procedure?
verfasst von
G. Currò
G. Iapichino
C. Lorenzini
R. Palmeri
E. Cucinotta
Publikationsdatum
01.02.2006
Erschienen in
Surgical Endoscopy / Ausgabe 2/2006
Print ISSN: 0930-2794
Elektronische ISSN: 1432-2218
DOI
https://doi.org/10.1007/s00464-005-0318-z

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