Skip to main content
Erschienen in: Surgical Endoscopy 4/2008

01.04.2008

Laparoscopic gastrectomy for gastric cancer: early experience among the elderly

verfasst von: K. K. Singh, A. Rohatgi, Iryna Rybinkina, Peter McCulloch, Satvinder Mudan

Erschienen in: Surgical Endoscopy | Ausgabe 4/2008

Einloggen, um Zugang zu erhalten

Abstract

Background

The data are scarce on the outcome for elderly patients presenting with resectable gastric cancer in the West who have been treated with minimally invasive surgery. This report presents the authors’ early experience with totally laparoscopic gastric resections for cancer in elderly patients.

Methods

A total of 20 patients underwent laparoscopic gastrectomy procedures: 14 distal, 5 subtotal, and 1 total gastrectomy. The male-to-female ratio was 15 to 5. The ages ranged from 75 to 88 years (mean, 80 years).

Results

All cases were managed laparoscopically with R0 resection. Four patients needed high-dependency unit care postoperatively. There were no perioperative deaths. The median time required for the procedure was 212 min, and time to diet was 4 days. The hospital stay was 8 days. Four patients experienced significant complications, with two patients requiring reoperation. The pathology was adenocarcinoma for 17 patients and high-grade dysplasia for 3 patients. Conclusion: Among elderly patients for whom conventional gastric surgery carries a high morbidity and mortality risk, minimal access surgery may offer equivalent oncologic integrity but with superior safety and economy. The primary aim is to remove the tumor with at least a D1 lymphadenectomy.
Literatur
1.
Zurück zum Zitat Cuschieri A, Weeden S, Fielding J, Bancewicz J, Craven J, Joypaul V, Sydes M, Fayers P (1999) Patient survival after D1 and D2 resections for gastric cancer: long-term results of the MRC randomized surgical trial. Br J Cancer 79:1522–1530PubMedCrossRef Cuschieri A, Weeden S, Fielding J, Bancewicz J, Craven J, Joypaul V, Sydes M, Fayers P (1999) Patient survival after D1 and D2 resections for gastric cancer: long-term results of the MRC randomized surgical trial. Br J Cancer 79:1522–1530PubMedCrossRef
2.
Zurück zum Zitat Bunt AM, Hermans J, Boon MC, Van de Velde CJ, Sasako M, Fleuren GJ, Bruijn JA (1994) Evaluation of the extent of lymphadenectomy in a randomized trial of Western- versus Japanese-type surgery in gastric cancer. J Clin Oncol 12:417–422PubMed Bunt AM, Hermans J, Boon MC, Van de Velde CJ, Sasako M, Fleuren GJ, Bruijn JA (1994) Evaluation of the extent of lymphadenectomy in a randomized trial of Western- versus Japanese-type surgery in gastric cancer. J Clin Oncol 12:417–422PubMed
3.
Zurück zum Zitat McCulloch P, Ward J, Tekkis PP, ASCOT group of surgeons (2003) British oesophagogastric cancer group: mortality and morbidity in gastro-oesophageal cancer surgery: initial results of ASCOT multicentre prospective cohort study. BMJ 327:1192–1197PubMedCrossRef McCulloch P, Ward J, Tekkis PP, ASCOT group of surgeons (2003) British oesophagogastric cancer group: mortality and morbidity in gastro-oesophageal cancer surgery: initial results of ASCOT multicentre prospective cohort study. BMJ 327:1192–1197PubMedCrossRef
4.
Zurück zum Zitat Sasako M, for the Dutch Gastric Cancer Study Group (1997) Risk factors for surgical treatment in the Dutch gastric cancer trial. Br J Surg 84:1567–1571PubMedCrossRef Sasako M, for the Dutch Gastric Cancer Study Group (1997) Risk factors for surgical treatment in the Dutch gastric cancer trial. Br J Surg 84:1567–1571PubMedCrossRef
5.
Zurück zum Zitat Bittner R, Butters M, Ulrich M, Uppenbrink S, Berger HG (1996) Total gastrectomy. updated operative mortality and long-term survival with particular reference to patients older then 70 years of age. Ann Surg 224:37–42PubMedCrossRef Bittner R, Butters M, Ulrich M, Uppenbrink S, Berger HG (1996) Total gastrectomy. updated operative mortality and long-term survival with particular reference to patients older then 70 years of age. Ann Surg 224:37–42PubMedCrossRef
6.
Zurück zum Zitat Pacelli F, Bellantone R, Doglietto GB, Perrri V, Genovese V, Tommasini O, Crucitti F (1991) Risk factors in relation to postoperative complications and mortality after total gastrectomy in aged patients. Am Surg 57:341–345PubMed Pacelli F, Bellantone R, Doglietto GB, Perrri V, Genovese V, Tommasini O, Crucitti F (1991) Risk factors in relation to postoperative complications and mortality after total gastrectomy in aged patients. Am Surg 57:341–345PubMed
7.
Zurück zum Zitat Law WL, Chu KW, Tung PH (2002) Laparoscopic colorectal resection: a safe option for elderly patients. J Am Coll Surg 195:768–773PubMedCrossRef Law WL, Chu KW, Tung PH (2002) Laparoscopic colorectal resection: a safe option for elderly patients. J Am Coll Surg 195:768–773PubMedCrossRef
8.
Zurück zum Zitat Stewart BT, Stitz RW, Lumley JW (1999) Laparoscopically assisted colorectal surgery in the elderly. Br J Surg 86:938–941PubMedCrossRef Stewart BT, Stitz RW, Lumley JW (1999) Laparoscopically assisted colorectal surgery in the elderly. Br J Surg 86:938–941PubMedCrossRef
9.
Zurück zum Zitat Weber DM (2003) Laparoscopic surgery: an excellent approach in elderly patients. Arch Surg 138:1083–1088PubMedCrossRef Weber DM (2003) Laparoscopic surgery: an excellent approach in elderly patients. Arch Surg 138:1083–1088PubMedCrossRef
10.
Zurück zum Zitat Yasuda K, Sonoda K, Shiroshita H, Inomata M, Shiraishi N, Kitano S (2004) Laparoscopically assisted distal gastrectomy for early gastric cancer in the elderly. BJS 91:1061–1065CrossRef Yasuda K, Sonoda K, Shiroshita H, Inomata M, Shiraishi N, Kitano S (2004) Laparoscopically assisted distal gastrectomy for early gastric cancer in the elderly. BJS 91:1061–1065CrossRef
11.
Zurück zum Zitat Kitano S, Iso Y, Moriyama M, Sugimachi K (1994) Laparoscopy-assisted Billroth I gastrectomy. Surg Laparosc Endosc 4:146–148PubMed Kitano S, Iso Y, Moriyama M, Sugimachi K (1994) Laparoscopy-assisted Billroth I gastrectomy. Surg Laparosc Endosc 4:146–148PubMed
12.
Zurück zum Zitat Ohashi S (1995) Laparoscopic intraluminal (intragastric) surgery for early gastric cancer: a new concept in laparoscopic surgery. Surg Endosc 9:169–171PubMedCrossRef Ohashi S (1995) Laparoscopic intraluminal (intragastric) surgery for early gastric cancer: a new concept in laparoscopic surgery. Surg Endosc 9:169–171PubMedCrossRef
13.
Zurück zum Zitat Ohgami M, Otani Y, Kumani K, Kubota T, Kim YI, Kitajima M (1999) Curative laparoscopic surgery for early gastric cancer: five years experience. World J Surg 23:187–192PubMedCrossRef Ohgami M, Otani Y, Kumani K, Kubota T, Kim YI, Kitajima M (1999) Curative laparoscopic surgery for early gastric cancer: five years experience. World J Surg 23:187–192PubMedCrossRef
14.
Zurück zum Zitat Tada M, Murakami A, Karita M, Yanai H, Okita K (1993) Endoscopic resection of early gastric cancer. Endoscopy 25:445–450PubMedCrossRef Tada M, Murakami A, Karita M, Yanai H, Okita K (1993) Endoscopic resection of early gastric cancer. Endoscopy 25:445–450PubMedCrossRef
15.
Zurück zum Zitat Kitano S, Shiraishi N (2004) Current status of laparoscopic gastrectomy for cancer in Japan. Surg Endosc; 18:182–185PubMedCrossRef Kitano S, Shiraishi N (2004) Current status of laparoscopic gastrectomy for cancer in Japan. Surg Endosc; 18:182–185PubMedCrossRef
16.
Zurück zum Zitat Adachi Y, Shiraishi N, Shiromizu A, Bandoh T, Aramaki M, Kitano S (2000) Laparoscopy-assisted Billroth I gastrectomy compared with conventional open gastrectomy. Arch Surg 135:806–810PubMedCrossRef Adachi Y, Shiraishi N, Shiromizu A, Bandoh T, Aramaki M, Kitano S (2000) Laparoscopy-assisted Billroth I gastrectomy compared with conventional open gastrectomy. Arch Surg 135:806–810PubMedCrossRef
17.
Zurück zum Zitat Kitano S, Shiraishi N, Fujii K, Yasuda K, Inomata M, Adachi YA (2002) Randomized controlled trial comparing open vs laparoscopy-assisted distal gastrectomy for the treatment of early gastric cancer: an interim report. Surgery 131:S306–S311PubMedCrossRef Kitano S, Shiraishi N, Fujii K, Yasuda K, Inomata M, Adachi YA (2002) Randomized controlled trial comparing open vs laparoscopy-assisted distal gastrectomy for the treatment of early gastric cancer: an interim report. Surgery 131:S306–S311PubMedCrossRef
18.
Zurück zum Zitat Adachi Y, Suematsu T, Shiraishi N, Katsuta T, Morimoto A, Kitano S, Akazawa K (1999) Quality of life after laparoscopy-assisted Billroth I gastrectomy. Ann Surg 229:49–54PubMedCrossRef Adachi Y, Suematsu T, Shiraishi N, Katsuta T, Morimoto A, Kitano S, Akazawa K (1999) Quality of life after laparoscopy-assisted Billroth I gastrectomy. Ann Surg 229:49–54PubMedCrossRef
19.
Zurück zum Zitat Goh PM, Alponat A, Mak K, Kum CK (1997) Early international results of laparoscopic gastrectomies. Surg Endosc 11:650–652PubMedCrossRef Goh PM, Alponat A, Mak K, Kum CK (1997) Early international results of laparoscopic gastrectomies. Surg Endosc 11:650–652PubMedCrossRef
20.
Zurück zum Zitat Husher CG, Mingoli A, Sgarzini G, Sansonetti A, Di Paola M, Recher A, Ponzano C (2005) Laparoscopic versus open subtotal gastrectomy for distal gastric cancer: five-year results of a randomized prospective trial. Ann Surg 241:232–237CrossRef Husher CG, Mingoli A, Sgarzini G, Sansonetti A, Di Paola M, Recher A, Ponzano C (2005) Laparoscopic versus open subtotal gastrectomy for distal gastric cancer: five-year results of a randomized prospective trial. Ann Surg 241:232–237CrossRef
21.
Zurück zum Zitat Munson JL, O’Mahony R (2005) Radical gastrectomy for cancer of the stomach. Surg Clin North Am 85:1021–1032PubMedCrossRef Munson JL, O’Mahony R (2005) Radical gastrectomy for cancer of the stomach. Surg Clin North Am 85:1021–1032PubMedCrossRef
22.
Zurück zum Zitat Roukos DH, Kappas AM (2005) Perspectives in the treatment of gastric cancer. Nat Clin Pract Oncol 2:98–107PubMedCrossRef Roukos DH, Kappas AM (2005) Perspectives in the treatment of gastric cancer. Nat Clin Pract Oncol 2:98–107PubMedCrossRef
23.
Zurück zum Zitat Mochiki E, Ohno T, Kamiyama Y, Aihara R, Nakabayashi T, Asao T, Kuwano H (2005) Laparoscopy-assisted gastrectomy for early gastric cancer in young and elderly patients. World J Surg 29:1585–1591PubMedCrossRef Mochiki E, Ohno T, Kamiyama Y, Aihara R, Nakabayashi T, Asao T, Kuwano H (2005) Laparoscopy-assisted gastrectomy for early gastric cancer in young and elderly patients. World J Surg 29:1585–1591PubMedCrossRef
24.
Zurück zum Zitat Reyes CD, Weber KJ, Gagner M, Divino CM (2001) Laparoscopic vs open gastrectomy: a retrospective review. Surg Endosc 15:928–931PubMedCrossRef Reyes CD, Weber KJ, Gagner M, Divino CM (2001) Laparoscopic vs open gastrectomy: a retrospective review. Surg Endosc 15:928–931PubMedCrossRef
25.
Zurück zum Zitat Azagra JS, Goergen M, De Simone P, Ibanez-Aguirre J (1999) Minimally invasive surgery for gastric cancer. Surg Endosc 13:351–357PubMedCrossRef Azagra JS, Goergen M, De Simone P, Ibanez-Aguirre J (1999) Minimally invasive surgery for gastric cancer. Surg Endosc 13:351–357PubMedCrossRef
26.
Zurück zum Zitat Sakuramoto S, Kikuchi S, Kuroyama S, Futawatari N, Katada N, Kobayashi N, Watanabe M (2006) Laparoscopy-assisted distal gastrectomy for early gastric cancer: experience with 111 consecutive patients. Surg Endosc 20:55–60PubMedCrossRef Sakuramoto S, Kikuchi S, Kuroyama S, Futawatari N, Katada N, Kobayashi N, Watanabe M (2006) Laparoscopy-assisted distal gastrectomy for early gastric cancer: experience with 111 consecutive patients. Surg Endosc 20:55–60PubMedCrossRef
27.
Zurück zum Zitat Orsenigo E, Carlucci M, Tomajer V, Di Palo S, Baccari P, Tamburini A, Mereu A, Staudacher C (2005) Gastrectomy and laparoscopic lymphadenectomy for carcinoma: preliminary experience with 59 cases. Suppl Tumori 4:S138PubMed Orsenigo E, Carlucci M, Tomajer V, Di Palo S, Baccari P, Tamburini A, Mereu A, Staudacher C (2005) Gastrectomy and laparoscopic lymphadenectomy for carcinoma: preliminary experience with 59 cases. Suppl Tumori 4:S138PubMed
28.
Zurück zum Zitat Dulucq JL, Wintringer P, Stabilini C, Solinas L, Perissat J, Mahajna A (2005) Laparoscopic and open gastric resections for malignant lesions: a prospective comparative study. Surg Endosc 19:933–938PubMedCrossRef Dulucq JL, Wintringer P, Stabilini C, Solinas L, Perissat J, Mahajna A (2005) Laparoscopic and open gastric resections for malignant lesions: a prospective comparative study. Surg Endosc 19:933–938PubMedCrossRef
29.
Zurück zum Zitat Kitagawa Y, Kitano S, Kubota T, Kumai K, Otani Y, Saikawa Y, Yoshida M, Kitajima M (2005) Minimally invasive surgery for gastric cancer: toward a confluence of two major streams: a review. Gastric Cancer 8:103–110PubMedCrossRef Kitagawa Y, Kitano S, Kubota T, Kumai K, Otani Y, Saikawa Y, Yoshida M, Kitajima M (2005) Minimally invasive surgery for gastric cancer: toward a confluence of two major streams: a review. Gastric Cancer 8:103–110PubMedCrossRef
30.
Zurück zum Zitat Rybinkina I, Rohatgi A, Wilkerson P, Forni L, Singh KK (2006) Quality of life after laparoscopic approach in surgery for cancer of the oesophagus and stomach (abstract). Br J Surg 93(S1):205 Rybinkina I, Rohatgi A, Wilkerson P, Forni L, Singh KK (2006) Quality of life after laparoscopic approach in surgery for cancer of the oesophagus and stomach (abstract). Br J Surg 93(S1):205
Metadaten
Titel
Laparoscopic gastrectomy for gastric cancer: early experience among the elderly
verfasst von
K. K. Singh
A. Rohatgi
Iryna Rybinkina
Peter McCulloch
Satvinder Mudan
Publikationsdatum
01.04.2008
Verlag
Springer-Verlag
Erschienen in
Surgical Endoscopy / Ausgabe 4/2008
Print ISSN: 0930-2794
Elektronische ISSN: 1432-2218
DOI
https://doi.org/10.1007/s00464-007-9561-9

Weitere Artikel der Ausgabe 4/2008

Surgical Endoscopy 4/2008 Zur Ausgabe

Update Chirurgie

Bestellen Sie unseren Fach-Newsletter und bleiben Sie gut informiert.

S3-Leitlinie „Diagnostik und Therapie des Karpaltunnelsyndroms“

Karpaltunnelsyndrom BDC Leitlinien Webinare
CME: 2 Punkte

Das Karpaltunnelsyndrom ist die häufigste Kompressionsneuropathie peripherer Nerven. Obwohl die Anamnese mit dem nächtlichen Einschlafen der Hand (Brachialgia parästhetica nocturna) sehr typisch ist, ist eine klinisch-neurologische Untersuchung und Elektroneurografie in manchen Fällen auch eine Neurosonografie erforderlich. Im Anfangsstadium sind konservative Maßnahmen (Handgelenksschiene, Ergotherapie) empfehlenswert. Bei nicht Ansprechen der konservativen Therapie oder Auftreten von neurologischen Ausfällen ist eine Dekompression des N. medianus am Karpaltunnel indiziert.

Prof. Dr. med. Gregor Antoniadis
Berufsverband der Deutschen Chirurgie e.V.

S2e-Leitlinie „Distale Radiusfraktur“

Radiusfraktur BDC Leitlinien Webinare
CME: 2 Punkte

Das Webinar beschäftigt sich mit Fragen und Antworten zu Diagnostik und Klassifikation sowie Möglichkeiten des Ausschlusses von Zusatzverletzungen. Die Referenten erläutern, welche Frakturen konservativ behandelt werden können und wie. Das Webinar beantwortet die Frage nach aktuellen operativen Therapiekonzepten: Welcher Zugang, welches Osteosynthesematerial? Auf was muss bei der Nachbehandlung der distalen Radiusfraktur geachtet werden?

PD Dr. med. Oliver Pieske
Dr. med. Benjamin Meyknecht
Berufsverband der Deutschen Chirurgie e.V.

S1-Leitlinie „Empfehlungen zur Therapie der akuten Appendizitis bei Erwachsenen“

Appendizitis BDC Leitlinien Webinare
CME: 2 Punkte

Inhalte des Webinars zur S1-Leitlinie „Empfehlungen zur Therapie der akuten Appendizitis bei Erwachsenen“ sind die Darstellung des Projektes und des Erstellungswegs zur S1-Leitlinie, die Erläuterung der klinischen Relevanz der Klassifikation EAES 2015, die wissenschaftliche Begründung der wichtigsten Empfehlungen und die Darstellung stadiengerechter Therapieoptionen.

Dr. med. Mihailo Andric
Berufsverband der Deutschen Chirurgie e.V.