Skip to main content
Erschienen in: Surgical Endoscopy 5/2010

01.05.2010 | New Technology

NOTES transanal rectal cancer resection using transanal endoscopic microsurgery and laparoscopic assistance

verfasst von: Patricia Sylla, David W. Rattner, Salvadora Delgado, Antonio M. Lacy

Erschienen in: Surgical Endoscopy | Ausgabe 5/2010

Einloggen, um Zugang zu erhalten

Abstract

Background

The feasibility and safety of Natural Orifice Translumenal Endoscopic Surgery (NOTES) transanal endoscopic rectosigmoid resection using transanal endoscopic microsurgery (TEM) was previously demonstrated in human cadavers and a porcine survival model. We report the first clinical case of a NOTES transanal resection for rectal cancer using TEM and laparoscopic assistance, performed by a team of surgeons from Barcelona and Boston with extensive experience with NOTES and minimally invasive approaches to colorectal diseases.

Methods

Transanal endoscopic rectal resection with total mesorectal excision using the TEM platform was performed in a 76-year-old woman with a T2N2 rectal cancer treated with preoperative chemoradiation. Laparoscopic visualization and assistance with retraction and exposure during rectosigmoid mobilization was provided through one 5-mm port, which was later used as the stoma site, and 2-mm needle ports, one of which was used as a drain site. The specimen was transected transanally followed by handsewn coloanal anastomosis.

Results

The procedure was completed successfully with an operative time of 4 hours and 30 minutes. Mesorectal excision was complete. The postoperative course was uneventful, and the patient was discharged on the fourth postoperative day. The final pathology demonstrated pT1N0 with 23 negative lymph nodes and negative proximal, distal, and radial margins.

Conclusions

NOTES transanal endoscopic rectosigmoid resection using TEM and laparoscopic assistance is feasible and safe. Careful patient selection and improvement in NOTES instrumentation are critical to optimize this approach before widespread clinical application.
Literatur
1.
Zurück zum Zitat Rao GV (2006). Transgastric appendectomy results and follow-up. (SAGES transgastric surgery panel). Presented at: SAGES meeting 2006 Rao GV (2006). Transgastric appendectomy results and follow-up. (SAGES transgastric surgery panel). Presented at: SAGES meeting 2006
2.
Zurück zum Zitat Della Flora E, Wilson TG, Martin IJ, O’Rourke NA, Maddern GJ (2008) A review of NOTES for intra-abdominal surgery. Ann Surg 247(4):583–602CrossRef Della Flora E, Wilson TG, Martin IJ, O’Rourke NA, Maddern GJ (2008) A review of NOTES for intra-abdominal surgery. Ann Surg 247(4):583–602CrossRef
3.
Zurück zum Zitat Marescaux J, Dallemagne B, Perretta S, Wattiez A, Mutter D, Coumaros D (2007) Surgery without scars: report of transluminal cholecystectomy in a human being. Arch Surg 142:823–826CrossRefPubMed Marescaux J, Dallemagne B, Perretta S, Wattiez A, Mutter D, Coumaros D (2007) Surgery without scars: report of transluminal cholecystectomy in a human being. Arch Surg 142:823–826CrossRefPubMed
4.
Zurück zum Zitat Lacy AM, Delgado S, Rojas OA, Almenara R, Blasi A, Llach J (2008) MA-NOS radical sigmoidectomy: report of a transvaginal resection in the human. Surg Endosc 22:1717–1723CrossRefPubMed Lacy AM, Delgado S, Rojas OA, Almenara R, Blasi A, Llach J (2008) MA-NOS radical sigmoidectomy: report of a transvaginal resection in the human. Surg Endosc 22:1717–1723CrossRefPubMed
5.
Zurück zum Zitat Lacy AM, Delgado S, Rojas OA, Ibarzabal A, Fernández G, Taura P (2009) Hybrid vaginal MA-NOS sleeve gastrectomy: technical note on the procedure in a patient. Surg Endosc 23(5):1130–1137CrossRefPubMed Lacy AM, Delgado S, Rojas OA, Ibarzabal A, Fernández G, Taura P (2009) Hybrid vaginal MA-NOS sleeve gastrectomy: technical note on the procedure in a patient. Surg Endosc 23(5):1130–1137CrossRefPubMed
6.
Zurück zum Zitat Decarli LA, Zorron R, Branco A, Lima FC, Tang M, Pioneer SR, Sanseverino JI, Menguer R, Bigolin AV, Gagner M (2009) New hybrid approach for NOTES transvaginal cholecystectomy: preliminary clinical experience. Surg Innov 16(2):181–186CrossRefPubMed Decarli LA, Zorron R, Branco A, Lima FC, Tang M, Pioneer SR, Sanseverino JI, Menguer R, Bigolin AV, Gagner M (2009) New hybrid approach for NOTES transvaginal cholecystectomy: preliminary clinical experience. Surg Innov 16(2):181–186CrossRefPubMed
7.
Zurück zum Zitat Palanivelu C, Rajan PS, Rangarajan M, Parthasarathi R, Senthilnathan P, Prasad M (2008) Transvaginal endoscopic appendectomy in humans: a unique approach to NOTES: world’s first report. Surg Endosc 22(5):1343–1347CrossRefPubMed Palanivelu C, Rajan PS, Rangarajan M, Parthasarathi R, Senthilnathan P, Prasad M (2008) Transvaginal endoscopic appendectomy in humans: a unique approach to NOTES: world’s first report. Surg Endosc 22(5):1343–1347CrossRefPubMed
8.
Zurück zum Zitat Horgan S, Cullen JP, Talamini MA, Mintz Y, Ferreres A, Jacobsen GR, Sandler B, Bosia J, Savides T, Easter DW, Savu MK, Ramamoorthy SL, Whitcomb E, Agarwal S, Lukacz E, Dominguez G, Ferraina P (2009) Natural orifice surgery: initial clinical experience. Surg Endosc 23:1512–1518CrossRefPubMed Horgan S, Cullen JP, Talamini MA, Mintz Y, Ferreres A, Jacobsen GR, Sandler B, Bosia J, Savides T, Easter DW, Savu MK, Ramamoorthy SL, Whitcomb E, Agarwal S, Lukacz E, Dominguez G, Ferraina P (2009) Natural orifice surgery: initial clinical experience. Surg Endosc 23:1512–1518CrossRefPubMed
9.
Zurück zum Zitat Alcaraz A, Peri L, Molina A, Goicoechea I, García E, Izquierdo L, Ribal MJ (2009) Feasibility of transvaginal NOTES-assisted laparoscopic nephrectomy. Eur Urol Sep 18 [Epub ahead of print] Alcaraz A, Peri L, Molina A, Goicoechea I, García E, Izquierdo L, Ribal MJ (2009) Feasibility of transvaginal NOTES-assisted laparoscopic nephrectomy. Eur Urol Sep 18 [Epub ahead of print]
10.
Zurück zum Zitat Auyang ED, Hungness ES, VAziri K, Martin JA, Soper NJ (2009) Natural orifice translumenal endoscopic surgery (NOTES): dissection for the critical view of safety during transcolonic cholecystectomy. Surg Endosc 23(5):1117–1118CrossRefPubMed Auyang ED, Hungness ES, VAziri K, Martin JA, Soper NJ (2009) Natural orifice translumenal endoscopic surgery (NOTES): dissection for the critical view of safety during transcolonic cholecystectomy. Surg Endosc 23(5):1117–1118CrossRefPubMed
11.
Zurück zum Zitat Fong DG, Ryou M, Pai RD, Tavakkolizadeh A, Rattner DW, Thompson CC (2007) Transcolonic ventral wall hernia mesh fixation in a porcine model. Endoscopy 39(10):865–869CrossRefPubMed Fong DG, Ryou M, Pai RD, Tavakkolizadeh A, Rattner DW, Thompson CC (2007) Transcolonic ventral wall hernia mesh fixation in a porcine model. Endoscopy 39(10):865–869CrossRefPubMed
12.
Zurück zum Zitat Fong DG, Pai RD, Thompson CC (2007) Transcolonic endoscopic abdominal exploration: a NOTES survival study in a porcine model. Gastrointest Endosc 65(2):312–318CrossRefPubMed Fong DG, Pai RD, Thompson CC (2007) Transcolonic endoscopic abdominal exploration: a NOTES survival study in a porcine model. Gastrointest Endosc 65(2):312–318CrossRefPubMed
13.
Zurück zum Zitat Ryou M, Fong DG, Pai RD, Tavakkolizadeh A, Rattner DW, Thompson CC (2007) Dual-port distal pancreatectomy using a prototype endoscope and endoscopic stapler: a natural orifice transluminal endoscopic surgery (NOTES) survival study in a porcine model. Endoscopy 39:881–887CrossRefPubMed Ryou M, Fong DG, Pai RD, Tavakkolizadeh A, Rattner DW, Thompson CC (2007) Dual-port distal pancreatectomy using a prototype endoscope and endoscopic stapler: a natural orifice transluminal endoscopic surgery (NOTES) survival study in a porcine model. Endoscopy 39:881–887CrossRefPubMed
14.
Zurück zum Zitat Wilhelm D, Meining A, von Delius S, Fiolka A, Can S, Hann von Weyhern C, Schneider A, Feussner H (2007) An innovative, safe and sterile sigmoid access (ISSA) for NOTES. Endoscopy 39:401–406CrossRefPubMed Wilhelm D, Meining A, von Delius S, Fiolka A, Can S, Hann von Weyhern C, Schneider A, Feussner H (2007) An innovative, safe and sterile sigmoid access (ISSA) for NOTES. Endoscopy 39:401–406CrossRefPubMed
15.
Zurück zum Zitat Moore JS, Cataldo PA, Osler T, Hyman NH (2008) Transanal endoscopic microsurgery is more effective than traditional transanal excision for resection of rectal masses. Dis Colon Rectum 51:1026–1031CrossRefPubMed Moore JS, Cataldo PA, Osler T, Hyman NH (2008) Transanal endoscopic microsurgery is more effective than traditional transanal excision for resection of rectal masses. Dis Colon Rectum 51:1026–1031CrossRefPubMed
16.
Zurück zum Zitat Swanstrom L (2000) Transanal endoscopic microsurgery: current indications and techniques. J Gastrointest Surg 4(4):342–343CrossRefPubMed Swanstrom L (2000) Transanal endoscopic microsurgery: current indications and techniques. J Gastrointest Surg 4(4):342–343CrossRefPubMed
17.
Zurück zum Zitat Tsai BM, Finne CO, Nordenstam JF, Christoforidis D, Madoff RD, Mellgren A (2010) Transanal endoscopic microsurgery resection of rectal tumors: outcome and recommendations. Dis Colon Rectum 53(1):16–23PubMed Tsai BM, Finne CO, Nordenstam JF, Christoforidis D, Madoff RD, Mellgren A (2010) Transanal endoscopic microsurgery resection of rectal tumors: outcome and recommendations. Dis Colon Rectum 53(1):16–23PubMed
18.
Zurück zum Zitat Cataldo PA, O’Brien S, Osler T (2005) Transanal endoscopic microsurgery: a prospective evaluation of functional results. Dis Colon Rectum 48:1366–1371CrossRefPubMed Cataldo PA, O’Brien S, Osler T (2005) Transanal endoscopic microsurgery: a prospective evaluation of functional results. Dis Colon Rectum 48:1366–1371CrossRefPubMed
19.
Zurück zum Zitat Whiteford MH, Denk PM, Swamstrom LL (2007) Feasibility of radical sigmoid colectomy performed as natural orifice translumenal endoscopic surgery (NOTES) using transanal endoscopic microsurgery. Surg Endosc 21:1870–1874CrossRefPubMed Whiteford MH, Denk PM, Swamstrom LL (2007) Feasibility of radical sigmoid colectomy performed as natural orifice translumenal endoscopic surgery (NOTES) using transanal endoscopic microsurgery. Surg Endosc 21:1870–1874CrossRefPubMed
20.
Zurück zum Zitat Sylla P, Willingham FF, Sohn DK, Gee D, Brugge WR, Rattner DW (2008) NOTES rectosigmoid resection using transanal endoscopic microsurgery (TEM) with transgastric endoscopic assistance: a pilot study in swine. J Gastrointest Surg 12:1717–1723CrossRefPubMed Sylla P, Willingham FF, Sohn DK, Gee D, Brugge WR, Rattner DW (2008) NOTES rectosigmoid resection using transanal endoscopic microsurgery (TEM) with transgastric endoscopic assistance: a pilot study in swine. J Gastrointest Surg 12:1717–1723CrossRefPubMed
21.
Zurück zum Zitat Sylla P, Sohn DK, Cizginer S, Konuk Y, Turner BG, Gee DW, Willingham FF, Hsu M, Mino-Kenudson M, Brugge WR, Rattner DW (2010) Survival study of NOTES rectosigmoid resection using transanal endoscopic microsurgery with or without transgastric endoscopic assistance in a swine model. Surg Endosc (in press) Sylla P, Sohn DK, Cizginer S, Konuk Y, Turner BG, Gee DW, Willingham FF, Hsu M, Mino-Kenudson M, Brugge WR, Rattner DW (2010) Survival study of NOTES rectosigmoid resection using transanal endoscopic microsurgery with or without transgastric endoscopic assistance in a swine model. Surg Endosc (in press)
22.
Zurück zum Zitat Shin EJ, Kalloo AN (2009) Transcolonic NOTES: current experience and potential implications for urologic applications. J Edourol 23(5):743–746CrossRef Shin EJ, Kalloo AN (2009) Transcolonic NOTES: current experience and potential implications for urologic applications. J Edourol 23(5):743–746CrossRef
23.
Zurück zum Zitat Cataldo PA (2006) Transanal endoscopic microsurgery. Surg Clin North Am 63:199–203 Cataldo PA (2006) Transanal endoscopic microsurgery. Surg Clin North Am 63:199–203
24.
Zurück zum Zitat Denk PM, Swanström LL, Whiteford MH (2008) Transanal endoscopic microsurgical platform for natural orifice surgery. Gastrointest Endosc 68:954–959CrossRefPubMed Denk PM, Swanström LL, Whiteford MH (2008) Transanal endoscopic microsurgical platform for natural orifice surgery. Gastrointest Endosc 68:954–959CrossRefPubMed
25.
Zurück zum Zitat Fajardo AD, Hunt SR, Fleshman JW, Mutch MG (2010) Transanal single-port low anterior resection in a cadaver model. Sur Endosc Jan 7 (Epub) Fajardo AD, Hunt SR, Fleshman JW, Mutch MG (2010) Transanal single-port low anterior resection in a cadaver model. Sur Endosc Jan 7 (Epub)
Metadaten
Titel
NOTES transanal rectal cancer resection using transanal endoscopic microsurgery and laparoscopic assistance
verfasst von
Patricia Sylla
David W. Rattner
Salvadora Delgado
Antonio M. Lacy
Publikationsdatum
01.05.2010
Verlag
Springer-Verlag
Erschienen in
Surgical Endoscopy / Ausgabe 5/2010
Print ISSN: 0930-2794
Elektronische ISSN: 1432-2218
DOI
https://doi.org/10.1007/s00464-010-0965-6

Weitere Artikel der Ausgabe 5/2010

Surgical Endoscopy 5/2010 Zur Ausgabe

News and notices

News and Notices

Update Chirurgie

Bestellen Sie unseren Fach-Newsletter und bleiben Sie gut informiert.

S3-Leitlinie „Diagnostik und Therapie des Karpaltunnelsyndroms“

Karpaltunnelsyndrom BDC Leitlinien Webinare
CME: 2 Punkte

Das Karpaltunnelsyndrom ist die häufigste Kompressionsneuropathie peripherer Nerven. Obwohl die Anamnese mit dem nächtlichen Einschlafen der Hand (Brachialgia parästhetica nocturna) sehr typisch ist, ist eine klinisch-neurologische Untersuchung und Elektroneurografie in manchen Fällen auch eine Neurosonografie erforderlich. Im Anfangsstadium sind konservative Maßnahmen (Handgelenksschiene, Ergotherapie) empfehlenswert. Bei nicht Ansprechen der konservativen Therapie oder Auftreten von neurologischen Ausfällen ist eine Dekompression des N. medianus am Karpaltunnel indiziert.

Prof. Dr. med. Gregor Antoniadis
Berufsverband der Deutschen Chirurgie e.V.

S2e-Leitlinie „Distale Radiusfraktur“

Radiusfraktur BDC Leitlinien Webinare
CME: 2 Punkte

Das Webinar beschäftigt sich mit Fragen und Antworten zu Diagnostik und Klassifikation sowie Möglichkeiten des Ausschlusses von Zusatzverletzungen. Die Referenten erläutern, welche Frakturen konservativ behandelt werden können und wie. Das Webinar beantwortet die Frage nach aktuellen operativen Therapiekonzepten: Welcher Zugang, welches Osteosynthesematerial? Auf was muss bei der Nachbehandlung der distalen Radiusfraktur geachtet werden?

PD Dr. med. Oliver Pieske
Dr. med. Benjamin Meyknecht
Berufsverband der Deutschen Chirurgie e.V.

S1-Leitlinie „Empfehlungen zur Therapie der akuten Appendizitis bei Erwachsenen“

Appendizitis BDC Leitlinien Webinare
CME: 2 Punkte

Inhalte des Webinars zur S1-Leitlinie „Empfehlungen zur Therapie der akuten Appendizitis bei Erwachsenen“ sind die Darstellung des Projektes und des Erstellungswegs zur S1-Leitlinie, die Erläuterung der klinischen Relevanz der Klassifikation EAES 2015, die wissenschaftliche Begründung der wichtigsten Empfehlungen und die Darstellung stadiengerechter Therapieoptionen.

Dr. med. Mihailo Andric
Berufsverband der Deutschen Chirurgie e.V.