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Erschienen in: Surgical Endoscopy 9/2021

23.09.2020

Does laparoscopic reoperation yield symptomatic improvements similar to those of primary laparoscopic Heller myotomy in achalasia patients?

verfasst von: Oscar Santes, Enrique Coss-Adame, Miguel A. Valdovinos, Janette Furuzawa-Carballeda, Angélica Rodríguez-Garcés, Jose Peralta-Figueroa, Sofia Narvaez-Chavez, Hector Olvera-Prado, Uriel Clemente-Gutiérrez, Gonzalo Torres-Villalobos

Erschienen in: Surgical Endoscopy | Ausgabe 9/2021

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Abstract

Background

Laparoscopic Heller myotomy fails in approximately 3.5% to 15% of patients. Evidence of successful laparoscopic reoperation is limited to a few studies.

Methods

This case–control study was conducted in patients who underwent laparoscopic Heller myotomy reoperation (LHM-R) from 2008 to 2016. The operative outcomes, preoperative and last follow-up manometric parameters, and symptom questionnaire results, including the Eckardt, Gastroesophageal Reflux Disease-Health Related Quality of Life (GERD-HRQL) and eating assessment tool (EAT-10) scores, were obtained. The data were compared with those of patients who underwent primary laparoscopic Heller myotomy (LHM-1).

Results

Thirty-five patients who underwent LHM-R and 35 patients who underwent LHM-1 were included. The reasons for failure in the LHM-R patient group included incomplete myotomy (71.4%), myotomy fibrosis (25.7%) and structural alterations in fundoplication (2.9%). The follow-up duration was 34 months for the LHM-R group and 24 months for the LHM-1 group (p = 0.557). The procedure was performed by laparoscopy in 100% of the patients in the two groups. No differences were found regarding surgical morbidity (11.4% LHM-R vs. 2.9% LHM-1, p = 0.164). The symptomatic outcomes were equivalent between groups (Eckardt p = 0.063, EAT–10 p = 0.166, GERD–HRQL p = 0.075). An IRP < 15 mmHg was achieved in 100% of the LHM-R and LHM-1 patients. At the last follow-up, 82.1% of the LHM-R patients and 91.4% of the LHM-1 patients were in symptomatic remission (p = 0.271).

Conclusion

The results achieved with LHM-R are similar to those achieved with LHM-1. Laparoscopic reoperation should be considered an effective and safe treatment after a failed Heller myotomy.
Literatur
1.
Zurück zum Zitat Furuzawa-Carballeda J, Aguilar-León D, Gamboa-Domínguez A, Valdovinos MA, Nuñez-Álvarez C, Martín-del-Campo LA, Enríquez AB, Coss-Adame E, Svarch AE, Flores-Nájera A, Villa-Baños A, Ceballos JC, Torres-Villalobos G (2015) Achalasia—An autoimmune inflammatory disease: a cross-sectional study. J Immunol Res 2015:1–18. https://doi.org/10.1155/2015/729217CrossRef Furuzawa-Carballeda J, Aguilar-León D, Gamboa-Domínguez A, Valdovinos MA, Nuñez-Álvarez C, Martín-del-Campo LA, Enríquez AB, Coss-Adame E, Svarch AE, Flores-Nájera A, Villa-Baños A, Ceballos JC, Torres-Villalobos G (2015) Achalasia—An autoimmune inflammatory disease: a cross-sectional study. J Immunol Res 2015:1–18. https://​doi.​org/​10.​1155/​2015/​729217CrossRef
3.
Zurück zum Zitat Furuzawa-Carballeda J, Zuñiga J, Hernández-Zaragoza DI, Barquera R, Marques-García E, Jiménez-Alvarez L, Cruz-Lagunas A, Ramírez G, Regino NE, Espinosa-Soto R, Yunis EJ, Romero-Hernández F, Azamar-Llamas D, Coss-Adame E, Valdovinos MA, Torres-Landa S, Palacios-Ramírez A, Breña B, Alejandro-Medrano E, Hernández-Ávila A, Granados J, Torres-Villalobos G (2018) An original Eurasian haplotype, HLA-DRB1*14:54-DQB1*05:03, influences the susceptibility to idiopathic achalasia. PLoS ONE 13:e0201676. https://doi.org/10.1371/journal.pone.0201676CrossRefPubMedPubMedCentral Furuzawa-Carballeda J, Zuñiga J, Hernández-Zaragoza DI, Barquera R, Marques-García E, Jiménez-Alvarez L, Cruz-Lagunas A, Ramírez G, Regino NE, Espinosa-Soto R, Yunis EJ, Romero-Hernández F, Azamar-Llamas D, Coss-Adame E, Valdovinos MA, Torres-Landa S, Palacios-Ramírez A, Breña B, Alejandro-Medrano E, Hernández-Ávila A, Granados J, Torres-Villalobos G (2018) An original Eurasian haplotype, HLA-DRB1*14:54-DQB1*05:03, influences the susceptibility to idiopathic achalasia. PLoS ONE 13:e0201676. https://​doi.​org/​10.​1371/​journal.​pone.​0201676CrossRefPubMedPubMedCentral
4.
Zurück zum Zitat Verne GN, Hahn AB, Pineau BC, Hoffman BJ, Wojciechowski BW, Wu WC (1999) Association of HLA-DR and -DQ alleles with idiopathic achalasia. Gastroenterology 117:26–31CrossRef Verne GN, Hahn AB, Pineau BC, Hoffman BJ, Wojciechowski BW, Wu WC (1999) Association of HLA-DR and -DQ alleles with idiopathic achalasia. Gastroenterology 117:26–31CrossRef
11.
13.
Zurück zum Zitat Zaninotto G, Costantini M, Portale G, Battaglia G, Molena D, Carta A, Costantino M, Nicoletti L, Ancona E (2002) Etiology, diagnosis, and treatment of failures after laparoscopic Heller myotomy for achalasia. Ann Surg 235:186–192CrossRef Zaninotto G, Costantini M, Portale G, Battaglia G, Molena D, Carta A, Costantino M, Nicoletti L, Ancona E (2002) Etiology, diagnosis, and treatment of failures after laparoscopic Heller myotomy for achalasia. Ann Surg 235:186–192CrossRef
15.
Zurück zum Zitat Guardino JM, Vela MF, Connor JT, Richter JE (2004) Pneumatic dilation for the treatment of achalasia in untreated patients and patients with failed Heller myotomy. J Clin Gastroenterol 38:855–860CrossRef Guardino JM, Vela MF, Connor JT, Richter JE (2004) Pneumatic dilation for the treatment of achalasia in untreated patients and patients with failed Heller myotomy. J Clin Gastroenterol 38:855–860CrossRef
23.
Zurück zum Zitat Ngamruengphong S, Inoue H, Ujiki MB, Patel LY, Bapaye A, Desai PN, Dorwat S, Nakamura J, Hata Y, Balassone V, Onimaru M, Ponchon T, Pioche M, Roman S, Rivory J, Mion F, Garros A, Draganov PV, Perbtani Y, Abbas A, Pannu D, Yang D, Perretta S, Romanelli J, Desilets D, Hayee B, Haji A, Hajiyeva G, Ismail A, Chen Y-I, Bukhari M, Haito-Chavez Y, Kumbhari V, Saxena P, Talbot M, Chiu PW-Y, Yip H-C, Wong VW-Y, Hernaez R, Maselli R, Repici A, Khashab MA (2017) Efficacy and safety of peroral endoscopic myotomy for treatment of achalasia after failed Heller myotomy. Clin Gastroenterol Hepatol 15:1531–1537.e3. https://doi.org/10.1016/j.cgh.2017.01.031CrossRefPubMed Ngamruengphong S, Inoue H, Ujiki MB, Patel LY, Bapaye A, Desai PN, Dorwat S, Nakamura J, Hata Y, Balassone V, Onimaru M, Ponchon T, Pioche M, Roman S, Rivory J, Mion F, Garros A, Draganov PV, Perbtani Y, Abbas A, Pannu D, Yang D, Perretta S, Romanelli J, Desilets D, Hayee B, Haji A, Hajiyeva G, Ismail A, Chen Y-I, Bukhari M, Haito-Chavez Y, Kumbhari V, Saxena P, Talbot M, Chiu PW-Y, Yip H-C, Wong VW-Y, Hernaez R, Maselli R, Repici A, Khashab MA (2017) Efficacy and safety of peroral endoscopic myotomy for treatment of achalasia after failed Heller myotomy. Clin Gastroenterol Hepatol 15:1531–1537.e3. https://​doi.​org/​10.​1016/​j.​cgh.​2017.​01.​031CrossRefPubMed
37.
Zurück zum Zitat Rossetti G, del Genio G, Maffettone V, Fei L, Brusciano L, Limongelli P, Pizza F, Tolone S, Di Martino M, del Genio F, del Genio A (2009) Laparoscopic reoperation with total fundoplication for failed Heller myotomy: is it a possible option? Personal experience and review of literature. Int Surg 94:330–334PubMed Rossetti G, del Genio G, Maffettone V, Fei L, Brusciano L, Limongelli P, Pizza F, Tolone S, Di Martino M, del Genio F, del Genio A (2009) Laparoscopic reoperation with total fundoplication for failed Heller myotomy: is it a possible option? Personal experience and review of literature. Int Surg 94:330–334PubMed
40.
Zurück zum Zitat Zaninotto G, Bennett C, Boeckxstaens G, Costantini M, Ferguson MK, Pandolfino JE, Patti MG, Ribeiro U, Richter J, Swanstrom L, Tack J, Triadafilopoulos G, Markar SR, Salvador R, Faccio L, Andreollo NA, Cecconello I, Costamagna G, da Rocha JRM, Hungness ES, Fisichella PM, Fuchs KH, Gockel I, Gurski R, Gyawali CP, Herbella FAM, Holloway RH, Hongo M, Jobe BA, Kahrilas PJ, Katzka DA, Dua KS, Liu D, Moonen A, Nasi A, Pasricha PJ, Penagini R, Perretta S, Sallum RAA, Sarnelli G, Savarino E, Schlottmann F, Sifrim D, Soper N, Tatum RP, Vaezi MF, van Herwaarden-Lindeboom M, Vanuytsel T, Vela MF, Watson DI, Zerbib F, Gittens S, Pontillo C, Vermigli S, Inama D, Low DE (2018) The 2018 ISDE achalasia guidelines. Dis Esophagus 31:83. https://doi.org/10.1093/dote/doy071CrossRef Zaninotto G, Bennett C, Boeckxstaens G, Costantini M, Ferguson MK, Pandolfino JE, Patti MG, Ribeiro U, Richter J, Swanstrom L, Tack J, Triadafilopoulos G, Markar SR, Salvador R, Faccio L, Andreollo NA, Cecconello I, Costamagna G, da Rocha JRM, Hungness ES, Fisichella PM, Fuchs KH, Gockel I, Gurski R, Gyawali CP, Herbella FAM, Holloway RH, Hongo M, Jobe BA, Kahrilas PJ, Katzka DA, Dua KS, Liu D, Moonen A, Nasi A, Pasricha PJ, Penagini R, Perretta S, Sallum RAA, Sarnelli G, Savarino E, Schlottmann F, Sifrim D, Soper N, Tatum RP, Vaezi MF, van Herwaarden-Lindeboom M, Vanuytsel T, Vela MF, Watson DI, Zerbib F, Gittens S, Pontillo C, Vermigli S, Inama D, Low DE (2018) The 2018 ISDE achalasia guidelines. Dis Esophagus 31:83. https://​doi.​org/​10.​1093/​dote/​doy071CrossRef
45.
Zurück zum Zitat Bonavina L, Nosadini A, Bardini R, Baessato M, Peracchia A (1992) Primary treatment of esophageal achalasia. Long-term results of myotomy and Dor fundoplication. Arch Surg 127:222–226 (discussion 227)CrossRef Bonavina L, Nosadini A, Bardini R, Baessato M, Peracchia A (1992) Primary treatment of esophageal achalasia. Long-term results of myotomy and Dor fundoplication. Arch Surg 127:222–226 (discussion 227)CrossRef
46.
Zurück zum Zitat Torres-Villalobos G, Coss-Adame E, Furuzawa-Carballeda J, Romero-Hernández F, Blancas-Breña B, Torres-Landa S, Palacios-Ramírez A, Alejandro-Medrano E, Hernández-Ávila A, Flores-Najera A, Ávila Escobedo LM, Ramírez Angulo C, Rodríguez-Garcés A, Valdovinos MÁ (2017) Dor vs toupet fundoplication after laparoscopic Heller myotomy: long-term randomized controlled trial evaluated by high-resolution manometry. J Gastrointest Surg 108:1238–1310. https://doi.org/10.1007/s11605-017-3578-8CrossRef Torres-Villalobos G, Coss-Adame E, Furuzawa-Carballeda J, Romero-Hernández F, Blancas-Breña B, Torres-Landa S, Palacios-Ramírez A, Alejandro-Medrano E, Hernández-Ávila A, Flores-Najera A, Ávila Escobedo LM, Ramírez Angulo C, Rodríguez-Garcés A, Valdovinos MÁ (2017) Dor vs toupet fundoplication after laparoscopic Heller myotomy: long-term randomized controlled trial evaluated by high-resolution manometry. J Gastrointest Surg 108:1238–1310. https://​doi.​org/​10.​1007/​s11605-017-3578-8CrossRef
47.
Zurück zum Zitat Bove A, Corbellini L, Catania A, Chiarini S, Bongarzoni G, Stella S, De Antoni E, De Matteo G (2001) Surgical controversies in the treatment of recurrent achalasia of the esophagus. Hepatogastroenterology 48:715–717PubMed Bove A, Corbellini L, Catania A, Chiarini S, Bongarzoni G, Stella S, De Antoni E, De Matteo G (2001) Surgical controversies in the treatment of recurrent achalasia of the esophagus. Hepatogastroenterology 48:715–717PubMed
53.
Zurück zum Zitat Smith KJ, Dobranowski J, Yip G, Dauphin A, Choi PT-L (2003) Cricoid pressure displaces the esophagus: an observational study using magnetic resonance imaging. Anesthesiology 99:60–64CrossRef Smith KJ, Dobranowski J, Yip G, Dauphin A, Choi PT-L (2003) Cricoid pressure displaces the esophagus: an observational study using magnetic resonance imaging. Anesthesiology 99:60–64CrossRef
Metadaten
Titel
Does laparoscopic reoperation yield symptomatic improvements similar to those of primary laparoscopic Heller myotomy in achalasia patients?
verfasst von
Oscar Santes
Enrique Coss-Adame
Miguel A. Valdovinos
Janette Furuzawa-Carballeda
Angélica Rodríguez-Garcés
Jose Peralta-Figueroa
Sofia Narvaez-Chavez
Hector Olvera-Prado
Uriel Clemente-Gutiérrez
Gonzalo Torres-Villalobos
Publikationsdatum
23.09.2020
Verlag
Springer US
Erschienen in
Surgical Endoscopy / Ausgabe 9/2021
Print ISSN: 0930-2794
Elektronische ISSN: 1432-2218
DOI
https://doi.org/10.1007/s00464-020-07978-7

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