Skip to main content
Erschienen in: Pediatric Nephrology 3/2006

01.03.2006 | Original Article

Continuous peritoneal dialysis in children: a single-centre experience in a developing country

verfasst von: Narayan Prasad, Sanjeev Gulati, Amit Gupta, Raj Kumar Sharma, Alok Kumar, Ramesh Kumar, Dhulipala V. S. Julu

Erschienen in: Pediatric Nephrology | Ausgabe 3/2006

Einloggen, um Zugang zu erhalten

Abstract

Continuous peritoneal dialysis (CPD) is the most commonly used modality of dialysis in children. Continuous ambulatory peritoneal dialysis (CAPD) has been an established form of therapy in adult patients with end-stage renal failure in India for more than a decade. There is a paucity of published experience of CPD in children from developing countries. We retrospectively studied children with end-stage renal failure (ESRD) that had been on CAPD over the past 10 years. Thirty patients with ESRD, mean age 13±8 years (range 5–21 years), male 18, were started on CAPD from 1994 to October 2004. The mean break-in period was 12±3 days. Of these 30 patients, 15 had a total of 21 episodes of peritonitis. The peritonitis rate was 0.58 episodes per patient year. E. coli was the commonest organism causing peritonitis. On outcome analysis, 7/30 (23.3%) patients received a renal transplant, while 11/30 (36.6%) continued on CAPD, awaiting a kidney transplant. Of the rest, eight (26.6%) patients died, two (6.7%) suffered technique failure and were changed to haemodialysis, and two (6.7%) were lost to follow-up after 2 months. The mean cumulative survival time of patient on CPD was 42 months. We conclude that CPD is a viable option for dialysis in ESRD children in a developing country and is a successful bridge between ESRD and renal transplantation
Literatur
1.
Zurück zum Zitat Warady BA, Hebert D, Sullian EK, Alexander SR, Tajan A (1997) Renal transplantation, chronic dialysis and chronic renal insufficiency in children and adolescents. The 1995 Annual Report of the North American Pediatric Renal Transplant Cooperative Study. Pediatr Nephrol 11:49–64CrossRefPubMed Warady BA, Hebert D, Sullian EK, Alexander SR, Tajan A (1997) Renal transplantation, chronic dialysis and chronic renal insufficiency in children and adolescents. The 1995 Annual Report of the North American Pediatric Renal Transplant Cooperative Study. Pediatr Nephrol 11:49–64CrossRefPubMed
2.
Zurück zum Zitat Alexander SR, Donaldson LA, Sullivan EK (1998) CAPD/CCPD for children in North America: The NAPRTCS experience. In: Fine RN, Alexander SR, Warady BA (eds) CAPD/CCPD in children, 2nd edn. Kluwer, Boston, pp 1–16 Alexander SR, Donaldson LA, Sullivan EK (1998) CAPD/CCPD for children in North America: The NAPRTCS experience. In: Fine RN, Alexander SR, Warady BA (eds) CAPD/CCPD in children, 2nd edn. Kluwer, Boston, pp 1–16
3.
Zurück zum Zitat Alexander SR, Salusky IB, Warady BA, Watkins SL (1997) Peritoneal dialysis workshop: Pediatric recommendations. Perit Dial Int 17 [Suppl 3]:S25–S27 Alexander SR, Salusky IB, Warady BA, Watkins SL (1997) Peritoneal dialysis workshop: Pediatric recommendations. Perit Dial Int 17 [Suppl 3]:S25–S27
4.
Zurück zum Zitat Salusky IB, Holloway M (1997) Selection of peritoneal dialysis for pediatric patients. Perit Dial Int 17 [Suppl 3]:S35–S37 Salusky IB, Holloway M (1997) Selection of peritoneal dialysis for pediatric patients. Perit Dial Int 17 [Suppl 3]:S35–S37
5.
Zurück zum Zitat Lingens N, Soergel M, Loiret C, Busch C, Lemmer B, Scharer K (1995) Ambulatory blood pressure monitoring in pediatric patients treated by regular hemodialysis and peritoneal dialysis. Pediatr Nephrol 9:167–172CrossRefPubMed Lingens N, Soergel M, Loiret C, Busch C, Lemmer B, Scharer K (1995) Ambulatory blood pressure monitoring in pediatric patients treated by regular hemodialysis and peritoneal dialysis. Pediatr Nephrol 9:167–172CrossRefPubMed
6.
Zurück zum Zitat Kaiser BA, Polinsky MS, Stover J, Morgenstern BZ, Baluarte HJ (1994) Growth of children following the initiation of dialysis: a comparison of three modalities. Pediatr Nephrol 8:733–738CrossRefPubMed Kaiser BA, Polinsky MS, Stover J, Morgenstern BZ, Baluarte HJ (1994) Growth of children following the initiation of dialysis: a comparison of three modalities. Pediatr Nephrol 8:733–738CrossRefPubMed
7.
Zurück zum Zitat Prasad N, Gupta A, Sharma RK, Prasad KN, Gulati S, Sharma AP (2003) Outcome of gram positive and gram negative peritonitis in patients on continuous ambulatory peritoneal dialysis: a single-center experience. Perit Dial Int 23 [Suppl 2]:S144–S147 Prasad N, Gupta A, Sharma RK, Prasad KN, Gulati S, Sharma AP (2003) Outcome of gram positive and gram negative peritonitis in patients on continuous ambulatory peritoneal dialysis: a single-center experience. Perit Dial Int 23 [Suppl 2]:S144–S147
8.
Zurück zum Zitat Oreopolus DG, Vas SI (1987) Peritonitis in continuous ambulatory peritoneal dialysis: making therapeutic decision easier. Arch Int Med 147:818–819CrossRef Oreopolus DG, Vas SI (1987) Peritonitis in continuous ambulatory peritoneal dialysis: making therapeutic decision easier. Arch Int Med 147:818–819CrossRef
9.
Zurück zum Zitat North American Pediatric Renal Transplant Cooperative Study (1997) Annual Data Report. EMMES Corporation, Potomac, MD, p 75 North American Pediatric Renal Transplant Cooperative Study (1997) Annual Data Report. EMMES Corporation, Potomac, MD, p 75
10.
Zurück zum Zitat Khoury AE, Charendoff J, Balfe JW, McLorie GA, Churchill BM (1991) Hernias associated with CAPD in children. Adv Perit Dial 7:279–282PubMed Khoury AE, Charendoff J, Balfe JW, McLorie GA, Churchill BM (1991) Hernias associated with CAPD in children. Adv Perit Dial 7:279–282PubMed
11.
Zurück zum Zitat Von Lilien T, Salusky IB, Yap HK, Fonkalsrud EW, Fine RN (1987) Hernias, a frequent complication in children treated with continuous peritoneal dialysis. Am J Kidney Dis 10:356–360PubMed Von Lilien T, Salusky IB, Yap HK, Fonkalsrud EW, Fine RN (1987) Hernias, a frequent complication in children treated with continuous peritoneal dialysis. Am J Kidney Dis 10:356–360PubMed
12.
Zurück zum Zitat Warady BA, Sullivan EK, Alexander SR (1996) Lesson from the pediatric dialysis patient database: a report of the North American Pediatric Renal Transplant Cooperative study. Kidney Int 49 [Suppl 53] S68–S71 Warady BA, Sullivan EK, Alexander SR (1996) Lesson from the pediatric dialysis patient database: a report of the North American Pediatric Renal Transplant Cooperative study. Kidney Int 49 [Suppl 53] S68–S71
13.
Zurück zum Zitat Port FK, Held PJ, Nolph KD, Turenne MN, Wolfe RA (1992) Risk of peritonitis and technique failure by CAPD connection technique: a national study. Kidney Int 42:967–974PubMed Port FK, Held PJ, Nolph KD, Turenne MN, Wolfe RA (1992) Risk of peritonitis and technique failure by CAPD connection technique: a national study. Kidney Int 42:967–974PubMed
14.
Zurück zum Zitat Warady BA, Campoy SF, Gross SP, Sedman AB, Lum GM (1984) Peritonitis with continuous ambulatory peritoneal dialysis and continuous cycling peritoneal dialysis. J Pediatr 105:726–730PubMed Warady BA, Campoy SF, Gross SP, Sedman AB, Lum GM (1984) Peritonitis with continuous ambulatory peritoneal dialysis and continuous cycling peritoneal dialysis. J Pediatr 105:726–730PubMed
15.
Zurück zum Zitat Levy M, Balfe JW (1994) Optimal approach to the prevention and treatment of peritonitis in children undergoing continuous ambulatory and continuous cycling peritoneal dialysis. Semin Dial 7:442–449 Levy M, Balfe JW (1994) Optimal approach to the prevention and treatment of peritonitis in children undergoing continuous ambulatory and continuous cycling peritoneal dialysis. Semin Dial 7:442–449
16.
Zurück zum Zitat Kingwatanakul P, Warady BA (1997) Staphylococcus nasal carriage in children receiving long-term peritoneal dialysis. Adv Perit Dial 13:280–283 Kingwatanakul P, Warady BA (1997) Staphylococcus nasal carriage in children receiving long-term peritoneal dialysis. Adv Perit Dial 13:280–283
17.
Zurück zum Zitat Gulati S, Stephens D, Balfe JA, Secker D, Harvey E, Balfe JW (2001) Children with hypoalbuminemia on continuous peritoneal dialysis are at risk for technique failure. Kidney Int 59:2361–2366PubMed Gulati S, Stephens D, Balfe JA, Secker D, Harvey E, Balfe JW (2001) Children with hypoalbuminemia on continuous peritoneal dialysis are at risk for technique failure. Kidney Int 59:2361–2366PubMed
18.
Zurück zum Zitat Young GA, Young JB, Young SM, Hobson SM, Hildreth B, Brownjohn AM, Parsons FM (1986) Nutrition and delayed hypersensitivity during continuous ambulatory peritoneal dialysis in relation to peritonitis. Nephron 43:177–186PubMed Young GA, Young JB, Young SM, Hobson SM, Hildreth B, Brownjohn AM, Parsons FM (1986) Nutrition and delayed hypersensitivity during continuous ambulatory peritoneal dialysis in relation to peritonitis. Nephron 43:177–186PubMed
19.
Zurück zum Zitat Fine RN, Ho M, North American Pediatric Renal Transplant Cooperative Study (2002) The role of APD in the management of pediatric patients: a report of the North American Pediatric Renal Transplant Cooperative Study. Semin Dial 15:427–429CrossRefPubMed Fine RN, Ho M, North American Pediatric Renal Transplant Cooperative Study (2002) The role of APD in the management of pediatric patients: a report of the North American Pediatric Renal Transplant Cooperative Study. Semin Dial 15:427–429CrossRefPubMed
20.
Zurück zum Zitat Donmez O, Aladag S, Cigerdelen N, Kocak S (2003) Outcome in children on chronic peritoneal dialysis. Adv Perit Dial 19:269–272PubMed Donmez O, Aladag S, Cigerdelen N, Kocak S (2003) Outcome in children on chronic peritoneal dialysis. Adv Perit Dial 19:269–272PubMed
21.
Zurück zum Zitat Romao Junior JE, Fares JA, Silva EC, Fadil MA, Abensur H, Massola VC, Marcondes M, Sabbaga E (1989) Continuous ambulatory peritoneal dialysis: efficient treatment for children with terminal uremia. Rev Assoc Med Bras 35:103–106 Romao Junior JE, Fares JA, Silva EC, Fadil MA, Abensur H, Massola VC, Marcondes M, Sabbaga E (1989) Continuous ambulatory peritoneal dialysis: efficient treatment for children with terminal uremia. Rev Assoc Med Bras 35:103–106
22.
Zurück zum Zitat Luque-Coqui M, Chartt R, Tercero G, Hernandez Roque A, Romero B, Morales F (2003) Self-esteem in Mexican pediatric patients on peritoneal dialysis and kidney transplantation. Nefrologia.23:145–149 Luque-Coqui M, Chartt R, Tercero G, Hernandez Roque A, Romero B, Morales F (2003) Self-esteem in Mexican pediatric patients on peritoneal dialysis and kidney transplantation. Nefrologia.23:145–149
Metadaten
Titel
Continuous peritoneal dialysis in children: a single-centre experience in a developing country
verfasst von
Narayan Prasad
Sanjeev Gulati
Amit Gupta
Raj Kumar Sharma
Alok Kumar
Ramesh Kumar
Dhulipala V. S. Julu
Publikationsdatum
01.03.2006
Verlag
Springer-Verlag
Erschienen in
Pediatric Nephrology / Ausgabe 3/2006
Print ISSN: 0931-041X
Elektronische ISSN: 1432-198X
DOI
https://doi.org/10.1007/s00467-005-2090-7

Weitere Artikel der Ausgabe 3/2006

Pediatric Nephrology 3/2006 Zur Ausgabe

Update Pädiatrie

Bestellen Sie unseren Fach-Newsletter und bleiben Sie gut informiert.