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Erschienen in: Pediatric Nephrology 10/2008

01.10.2008 | Original Article

The spectrum of chronic kidney disease (stages 2–5) in KwaZulu-Natal, South Africa

verfasst von: Rajendra Bhimma, Miriam Adhikari, Kareshma Asharam, Catherine Connolly

Erschienen in: Pediatric Nephrology | Ausgabe 10/2008

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Abstract

The burden of chronic kidney disease (CKD) in children in developing countries remains unknown, due to the lack of a national data-reporting system. We undertook a retrospective study of all children < 16 years old in our hospital, which is the tertiary referral centre for children with complex kidney disorders, to analyse the spectrum of CKD (stages 2–5) from 1994–2006. Six hundred and fifty-three children with kidney disorders were screened for CKD; 286 (44.0%) were < 5 years old. Of these, 177 (62%) were male, 202 (70.6%) were black, 77 (26.9%) were Indian, five (1.8%) were mixed race and two (0.7%) were white. One hundred and twenty-six children had CKD (stages 2–5); 55 (43.7%) were < 5 years olds; 41 (74.5%) were male. There were 71 (56.3%) that were > 5 years old, 42 (59.2%) were male. The commonest cause of CKD (stages 2–5) in all children was nephrotic syndrome, comprising 30.9% in children < 5 years old and 40.8% in children > 5 years old. Within the observation period of 11 years, end-stage kidney disease was diagnosed in 20 children; only nine had been on long-term dialysis, and seven qualified for transplantation. Five (25%) children had died, four from sepsis during dialysis and one from tuberculosis after receiving a transplant. We concluded that lack of resources, late referrals, and high cost of renal replacement therapy in developing countries leads to poor outcome in CKD.
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Metadaten
Titel
The spectrum of chronic kidney disease (stages 2–5) in KwaZulu-Natal, South Africa
verfasst von
Rajendra Bhimma
Miriam Adhikari
Kareshma Asharam
Catherine Connolly
Publikationsdatum
01.10.2008
Verlag
Springer Berlin Heidelberg
Erschienen in
Pediatric Nephrology / Ausgabe 10/2008
Print ISSN: 0931-041X
Elektronische ISSN: 1432-198X
DOI
https://doi.org/10.1007/s00467-008-0871-5

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