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Erschienen in: Pediatric Nephrology 8/2010

01.08.2010 | Original Article

Vesicoureteral reflux in children with suspected and proven urinary tract infection

verfasst von: Annukka Hannula, Mika Venhola, Marjo Renko, Tytti Pokka, Niilo-Pekka Huttunen, Matti Uhari

Erschienen in: Pediatric Nephrology | Ausgabe 8/2010

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Abstract

The aim of this study was to estimate the prevalence of vesicoureteral reflux (VUR) and clinically significant ultrasonography (US) abnormalities in a large group of children with proven and suspected urinary tract infection (UTI). The medical reports on renal US and voiding cystouretrographies (VCUG) of 2,036 children were reviewed. Renal US was performed on all children and VCUG on 1,185 children (58%). Based on the urine culture data, the UTI diagnoses were classified into five reliability classes (proven, likely, unlikely, false and no microbial data). The UTI diagnose was considered proven in 583/2036 (28.6%) and false in 145 (7.1%) cases. The prevalence of VUR was similar among those with proven and false UTI [37.4 vs. 34.8%; relative risk (RR) 1.08, 95% confidence intervals (95% CI) 0.7–1.7, P = 0.75] and decreased with increasing age (P = 0.001). Clinically significant US abnormalities occurred in 87/583 (14.9%) cases with proven UTI and significantly less often (11/145, 7.6%) in the false UTI class (RR 1.96, 95% CI 1.1–3.6, P = 0.02). Our finding supports the claim that VUR is not significantly associated to UTI and that its occurrence among children even without UTI is significantly higher than traditional estimates. This challenges the recommendations of routine VCUG after UTI.
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Metadaten
Titel
Vesicoureteral reflux in children with suspected and proven urinary tract infection
verfasst von
Annukka Hannula
Mika Venhola
Marjo Renko
Tytti Pokka
Niilo-Pekka Huttunen
Matti Uhari
Publikationsdatum
01.08.2010
Verlag
Springer-Verlag
Erschienen in
Pediatric Nephrology / Ausgabe 8/2010
Print ISSN: 0931-041X
Elektronische ISSN: 1432-198X
DOI
https://doi.org/10.1007/s00467-010-1542-x

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