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Geomagnetic field modulates artificial static magnetic field effect on arterial baroreflex and on microcirculation

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An Erratum to this article was published on 16 November 2006

An Erratum to this article was published on 16 November 2006

An Erratum to this article was published on 16 November 2006

An Erratum to this article was published on 16 November 2006

Abstract

Spreading evidence suggests that geomagnetic field (GMF) modulates artificial magnetic fields biological effect and associated with increased cardiovascular morbidity. To explore the underlying physiological mechanism we studied 350 mT static magnetic field (SMF) effect on arterial baroreflex-mediated skin microcirculatory response in conjunction with actual geomagnetic activity, reflected by K and K p indices. Fourteen experiments were performed in rabbits sedated by pentobarbital infusion (5 mg/kg/h). Mean femoral artery blood pressure, heart rate, and the ear lobe skin microcirculatory blood flow, measured by microphotoelectric plethysmogram (MPPG), were simultaneously recorded before and after 40 min of NdFeB magnets local exposure to sinocarotid baroreceptors. Arterial baroreflex sensitivity (BRS) was estimated from heart rate/blood pressure response to intravenous bolus injections of nitroprusside and phenylephrine. We found a significant positive correlation between SMF-induced increase in BRS and increment in microvascular blood flow (ΔBRS with ΔMPPG, r=0.7, p<0.009) indicated the participation of the arterial baroreflex in the regulation of the microcirculation and its enhancement after SMF exposure. Geomagnetic disturbance, as opposed to SMF, decreased both microcirculation and BRS, and counteracted SMF-induced increment in microcirculatory blood flow (K-index with ΔMPPG; r s=−0.55, p<0.041). GMF probably affected central baroreflex pathways, diminishing SMF direct stimulatory effect on sinocarotid baroreceptors and on baroreflex-mediated vasodilatatory response. The results herein may thus point to arterial baroreflex as a possible physiological mechanism for magnetic-field cardiovascular effect. It seems that geomagnetic disturbance modifies artificial magnetic fields biological effect and should be taken into consideration in the assessment of the final effect.

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Acknowledgments

This research was carried out under the auspices of the Japanese Government Research Awards for Foreign Specialists, administrated by the Science and Technology Agency of Japan at the Department of Environmental Health in the National Institute of Public Health in Tokyo, Japan.

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Authors and Affiliations

  1. Department of Environmental Health, National Institute of Public Health, Tokyo, 108, Japan

    Juraj Gmitrov

  2. Pro Vitae Hospital, Gelnica, 056 01, Slovak Republic

    Juraj Gmitrov

  3. Visnova 6, Presov, 080 01, Slovak Republic

    Juraj Gmitrov

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Correspondence to Juraj Gmitrov.

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An erratum to this article can be found at http://dx.doi.org/10.1007/s00484-006-0063-6

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Gmitrov, J. Geomagnetic field modulates artificial static magnetic field effect on arterial baroreflex and on microcirculation. Int J Biometeorol 51, 335–344 (2007). https://doi.org/10.1007/s00484-006-0056-5

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  • DOI: https://doi.org/10.1007/s00484-006-0056-5

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