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Erschienen in: Supportive Care in Cancer 3/2009

01.03.2009 | Original Article

Screening the nutritional status in oncology: a preliminary report on 1,000 outpatients

verfasst von: Federico Bozzetti, on behalf of the SCRINIO Working Group

Erschienen in: Supportive Care in Cancer | Ausgabe 3/2009

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Abstract

Objective

This study presents the preliminary data of a prospective multi-centre investigation on the screening of the nutritional status of cancer outpatients with the purpose to define: (1) prevalence and rate of weight loss and nutritional risk in this patient population, and (2) to assess the association among some patient-dependent, tumour-dependent and therapy-dependent variables with the nutritional status and the nutritional risk.

Materials and methods

Seventeen centres were involved to collect demographic data (age and sex), oncologic data (site of primary tumour, stage, Eastern Cooperative Oncology Group Performance State, oncologic therapy) and presence and severity of systemic and digestive/nutritional symptoms (fatigue, anorexia, nausea/vomiting, early satiety, dysgeusia/dysosmia, dysphagia/odynophagia, diarrhoea/constipation). Furthermore, the percentage of the weight loss on the usual body weight and the body mass index were computed. The nutritional risk was assessed according to the Nutrition Risk Screening 2002 questionnaire which scores the risk from 0 to 7.

Main results

On the first 1,000 screened patients, a significant weight loss (≥10%) and a nutritional risk score ≥3 were observed in 39.7% and 33.8% of patients, respectively. Weight loss was higher in upper gastrointestinal tumours, in advanced stages of disease and in patients with a poor performance status. Similarly, the nutritional risk was higher in esophageal and pancreatic cancer and in those with a worse performance status. There was a good correlation between the severity of anorexia and the rate of the weight loss The majority of patients with no weight loss or a weight loss <10% were not anorectic; on the contrary, the majority of those with more severe weight loss had some degree of anorexia.

Conclusions

Weight loss and nutritional risk are frequent in an unselected series of cancer outpatients. Site of primary tumour, stage and performance state appear to be associated, at a preliminary analysis, with significant weight loss and nutritional risk. Anorexia and weight loss are closely related, and this supports the concept that nutritional depletion can play a major role in the onset of malnutrition-cachexia.
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Metadaten
Titel
Screening the nutritional status in oncology: a preliminary report on 1,000 outpatients
verfasst von
Federico Bozzetti
on behalf of the SCRINIO Working Group
Publikationsdatum
01.03.2009
Verlag
Springer-Verlag
Erschienen in
Supportive Care in Cancer / Ausgabe 3/2009
Print ISSN: 0941-4355
Elektronische ISSN: 1433-7339
DOI
https://doi.org/10.1007/s00520-008-0476-3

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