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Supportive Care in Cancer

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01.03.2015 | Commentary

Mind the gaps: missed opportunities to promote bone health among cancer survivors

verfasst von: Hawley C. Almstedt, Heather P. Tarleton

Erschienen in: Supportive Care in Cancer | Ausgabe 3/2015

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Abstract

Introduction

Many cancer treatments have a negative effect on bone health and can lead to osteoporosis. Additionally, the risk of osteoporosis during cancer survivorship may differ by racial and ethnic group. Overall, cancer survivors may be poorly informed about the risk of bone loss due to treatment.

Exercise prescription

Exercise can be prescribed to improve bone health and reduce risk of fracture. Women participating in the Improving Physical Activity After Cancer Treatment pilot study (IMPAACT) experienced significant improvements in bone health. The pilot work also suggests that cancer survivors of diverse racial/ethnic profiles may not fit the normal risk profile for osteoporosis and could be overlooked during screening.

In summary

The lack of awareness of poor bone health in cancer survivors needs to be addressed, especially for those who do not fit the normal osteoporosis risk profile. Exercise is a safe and effective part of a cancer survivorship plan and is useful in promoting bone health.

Gralow JR, Biermann JS, Farooki A, Fornier MN, Gagel RF, Kumar R, Litsas G, McKay R, Podoloff DA, Srinivas S, Van Poznak CH (2013) NCCN task force report: bone health in cancer care. Journal of the National Comprehensive Cancer Network : JNCCN 11 Suppl 3:S1-50; quiz S51

Tipples K, Robinson A (2011) Optimal management of cancer treatment-induced bone loss: considerations for elderly patients. Drugs Aging 28(11):867–883. doi:10.2165/11595820-000000000-00000 PubMedCrossRef

Conde DM, Costa-Paiva L, Martinez EZ, Mendes Pinto-Neto A (2012) Low bone mineral density in middle-aged breast cancer survivors: prevalence and associated factors. Breast care 7(2):121–125. doi:10.1159/000337763 PubMedCentralPubMedCrossRef

Stavraka C, Maclaran K, Gabra H, Agarwal R, Ghaem-Maghami S, Taylor A, Dhillo WS, Panay N, Blagden SP (2013) A study to evaluate the cause of bone demineralization in gynecological cancer survivors. Oncologist 18(4):423–429. doi:10.1634/theoncologist. 2012-0416 PubMedCentralPubMedCrossRef

Nishio K, Tanabe A, Maruoka R, Nakamura K, Takai M, Sekijima T, Tunetoh S, Terai Y, Ohmichi M (2013) Bone mineral loss induced by anticancer treatment for gynecological malignancies in premenopausal women. Endocr Connect 2(1):11–17. doi:10.1530/EC-12-0043 PubMedCentralPubMedCrossRef

Wasnich RD, Miller PD (2000) Antifracture efficacy of antiresorptive agents are related to changes in bone density. J Clin Endocrinol Metab 85(1):231–236PubMedCrossRef

Blake ML, Tometsko M, Miller R, Jones JC, Dougall WC (2014) RANK expression on breast cancer cells promotes skeletal metastasis. Clin Exp Metastasis 31(2):233–245. doi:10.1007/s10585-013-9624-3 PubMedCrossRef

Zhang X, Junior CR, Liu M, Li F, D’Silva NJ, Kirkwood KL (2013) Oral squamous carcinoma cells secrete RANKL directly supporting osteolytic bone loss. Oral Oncol 49(2):119–128. doi:10.1016/j.oraloncology.2012.08.004 PubMedCentralPubMedCrossRef

Taxel P, Choksi P, Van Poznak C (2012) The management of osteoporosis in breast cancer survivors. Maturitas 73(4):275–279. doi:10.1016/j.maturitas.2012.08.009 PubMedCentralPubMedCrossRef

10.

Vehmanen LK, Elomaa I, Blomqvist CP, Saarto T (2014) The effect of ovarian dysfunction on bone mineral density in breast cancer patients 10 years after adjuvant chemotherapy. Acta Oncol 53(1):75–79. doi:10.3109/0284186X.2013.792992 PubMedCrossRef

11.

Siris ES, Miller PD, Barrett-Connor E, Faulkner KG, Wehren LE, Abbott TA, Berger ML, Santora AC, Sherwood LM (2001) Identification and fracture outcomes of undiagnosed low bone mineral density in postmenopausal women: results from the National Osteoporosis Risk Assessment. JAMA 286(22):2815–2822PubMedCrossRef

12.

Kanis JA, Oden A, Johansson H, Borgstrom F, Strom O, McCloskey E (2009) FRAX and its applications to clinical practice. Bone 44(5):734–743. doi:10.1016/j.bone.2009.01.373 PubMedCrossRef

13.

Chen Z, Maricic M, Bassford TL, Pettinger M, Ritenbaugh C, Lopez AM, Barad DH, Gass M, Leboff MS (2005) Fracture risk among breast cancer survivors: results from the Women’s Health Initiative Observational study. Arch Intern Med 165(5):552–558. doi:10.1001/archinte.165.5.552 PubMedCrossRef

14.

Cummings SR, Melton LJ (2002) Epidemiology and outcomes of osteoporotic fractures. Lancet 359(9319):1761–1767. doi:10.1016/S0140-6736(02)08657-9 PubMedCrossRef

15.

Burge R, Dawson-Hughes B, Solomon DH, Wong JB, King A, Tosteson A (2007) Incidence and economic burden of osteoporosis-related fractures in the United States, 2005–2025. J Bone Miner Res 22(3):465–475. doi:10.1359/jbmr.061113 PubMedCrossRef

16.

Schmitz KH, Courneya KS, Matthews C, Demark-Wahnefried W, Galvao DA, Pinto BM, Irwin ML, Wolin KY, Segal RJ, Lucia A, Schneider CM, Von Gruenigen VE, Schwartz AL, American College of Sports Medicine (2010) American College of Sports Medicine roundtable on exercise guidelines for cancer survivors. Med Sci Sports Exerc 42(7):1409–1426. doi:10.1249/MSS.0b013e3181e0c112 PubMedCrossRef

17.

Schultz PN, Stava C, Beck ML, Vassilopoulou-Sellin R (2004) Ethnic/racial influences on the physiologic health of cancer survivors. Cancer 100(1):156–164. doi:10.1002/cncr.11897 PubMedCrossRef

18.

Tripathy D, Durie BG, Mautner B, Ferenz KS, Moul JW (2014) Awareness, concern, and communication between physicians and patients on bone health in cancer supportive care in cancer. J Multinatl Assoc Support Care Cancer 22(6):1601–1610. doi:10.1007/s00520-014-2127-1 CrossRef

19.

McKean H, Looker S, Hartmann LC, Hayman SR, Kaur JS, McWilliams RR, Peethambaram PP, Stahl JF, Jatoi A (2008) Are cancer survivors/patients knowledgeable about osteoporosis? Results from a survey of 285 chemotherapy-treated cancer patients and their companions. J Nutr Educ Behav 40(3):144–148. doi:10.1016/j.jneb.2007.08.009 PubMedCrossRef

20.

Kohrt WM, Bloomfield SA, Little KD, Nelson ME, Yingling VR (2004) American College of Sports Medicine Position Stand: physical activity and bone health. Med Sci Sports Exerc 36(11):1985–1996PubMedCrossRef

21.

National Osteoporosis Foundation (2014) Exercise for strong bones. National Osteoporosis Foundation. www.nof.org. Accessed Retrieved on 22 July, 2014

Titel: Mind the gaps: missed opportunities to promote bone health among cancer survivors
verfasst von: Hawley C. Almstedt
Heather P. Tarleton
Publikationsdatum: 01.03.2015
Verlag: Springer Berlin Heidelberg
Erschienen in: Supportive Care in Cancer / Ausgabe 3/2015
Print ISSN: 0941-4355
Elektronische ISSN: 1433-7339
DOI: https://doi.org/10.1007/s00520-014-2497-4

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