Erschienen in:
22.06.2019 | Review Article
Deglutition disorders as a consequence of head and neck cancer therapies: a systematic review and meta-analysis
verfasst von:
Isabela Porto de Toledo, Leticia Lopes Quirino Pantoja, Karen Fontes Luchesi, Daniele Xavier Assad, Graziela De Luca Canto, Eliete Neves Silva Guerra
Erschienen in:
Supportive Care in Cancer
|
Ausgabe 10/2019
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Abstract
Purpose
In this study, we aimed to estimate the frequency of deglutition disorders in patients pre- and post-treatment for head and neck cancer (HNC).
Methods
Search strategies were developed for the following databases: LILACS, PubMed, SpeechBITE, LIVIVO, Web of Science, and Scopus. Additionally, the gray literature was searched using Google Scholar, OpenGrey, and ProQuest. Only studies that conducted an evaluation of deglutition before and after cancer treatment and had sufficient quantitative data were included. We conducted a proportion of random effects meta-analysis using R statistical software.
Results
Seventeen studies were included. Aspiration showed a high frequency in the period less than 3 months post-treatment, with 28.6% (total sample = 229). Penetration of fluids above the vocal folds and reduced laryngeal elevation were more frequent in the period less than 6 months post-treatment.
Conclusion
The frequency of deglutition disorders and its complications, such as aspiration, appears to be higher in the immediate to 6-month post-treatment period in patients with HNC. The parameter pharyngeal residue continued to increase through the period analyzed.