Skip to main content
Erschienen in: Journal of Hepato-Biliary-Pancreatic Sciences 6/2010

01.11.2010 | Topics

Distal pancreatectomy with preservation of the spleen

verfasst von: Andrew L. Warshaw

Erschienen in: Journal of Hepato-Biliary-Pancreatic Sciences | Ausgabe 6/2010

Einloggen, um Zugang zu erhalten

Abstract

Distal pancreatectomy (resection of the pancreatic body and tail) can be performed with or without preservation of the spleen. Splenic preservation has the advantages of fewer postoperative complications such as abscesses in the resection bed, shorter length of hospitalization, and avoidance of the long-term risk of post-splenectomy sepsis related to encapsulated bacteria. Two techniques can be used to save the spleen: either by dissecting out the splenic artery and vein with division of the arterial and venous branches between the pancreas and the splenic artery and vein; or by resecting the splenic artery and vein along with the pancreas but with careful preservation of the vascular collaterals in the splenic hilum, which allows the spleen to survive on the short gastric vessels (Warshaw technique). The latter method has been shown to be associated with a shorter operation, less blood loss, and a shorter hospitalization. In general the Warshaw technique is easier, especially for laparoscopic pancreatectomy. The subsequent appearance of enlarged gastric veins (varices) is to be expected as a consequence of loss of the splenic vein but has not led to bleeding from these natural collaterals during long-term follow up.
Literatur
1.
Zurück zum Zitat Shoup M, Brennan MF, McWhite K, Leung DHY, Klimstra D, Conlon KC. The value of splenic preservation with distal pancreatectomy. Arch Surg. 2002;137:164–8.CrossRefPubMed Shoup M, Brennan MF, McWhite K, Leung DHY, Klimstra D, Conlon KC. The value of splenic preservation with distal pancreatectomy. Arch Surg. 2002;137:164–8.CrossRefPubMed
2.
Zurück zum Zitat Carrère N, Abid S, Julio CH, Bloom E, Pradère B. Spleen-preserving distal pancreatectomy with excision of splenic artery and vein: a case-matched comparison with conventional distal pancreatectomy with splenectomy. World J Surg. 2007;31:375–82.CrossRefPubMed Carrère N, Abid S, Julio CH, Bloom E, Pradère B. Spleen-preserving distal pancreatectomy with excision of splenic artery and vein: a case-matched comparison with conventional distal pancreatectomy with splenectomy. World J Surg. 2007;31:375–82.CrossRefPubMed
3.
Zurück zum Zitat Benoist S, Dugué L, Sauvanet A, Valverde A, Mauvais A, Pate F, et al. Is there a role of preservation of the spleen in distal pancreatectomy? J Am Coll Surg. 1999;188:255–60.CrossRefPubMed Benoist S, Dugué L, Sauvanet A, Valverde A, Mauvais A, Pate F, et al. Is there a role of preservation of the spleen in distal pancreatectomy? J Am Coll Surg. 1999;188:255–60.CrossRefPubMed
4.
Zurück zum Zitat Sledzianowski JF, Duffas JP, Muscari F, Suc B, Fourtanier F. Risk factors for mortality and intra-abdominal morbidity after distal pancreatectomy. Surgery. 2005;137:180–5.CrossRefPubMed Sledzianowski JF, Duffas JP, Muscari F, Suc B, Fourtanier F. Risk factors for mortality and intra-abdominal morbidity after distal pancreatectomy. Surgery. 2005;137:180–5.CrossRefPubMed
5.
Zurück zum Zitat Holdsworth RJ, Irving AD, Cuschieri A. Postsplenectomy sepsis and its mortality rate: actual versus perceived risks. Br J Surg. 1991;78:1031–8.CrossRefPubMed Holdsworth RJ, Irving AD, Cuschieri A. Postsplenectomy sepsis and its mortality rate: actual versus perceived risks. Br J Surg. 1991;78:1031–8.CrossRefPubMed
6.
Zurück zum Zitat Lutwick LI. Life threatening infections in the asplenic or hyposplenic individual. Curr Clin Top Infect Dis. 2002;22:78–96.PubMed Lutwick LI. Life threatening infections in the asplenic or hyposplenic individual. Curr Clin Top Infect Dis. 2002;22:78–96.PubMed
7.
Zurück zum Zitat Lynch AM, Kapila R. Overwhelming postsplenectomy infection. Infect Dis Clin North Am. 1996;10:693–707.CrossRefPubMed Lynch AM, Kapila R. Overwhelming postsplenectomy infection. Infect Dis Clin North Am. 1996;10:693–707.CrossRefPubMed
8.
Zurück zum Zitat Robinette CD, Fraumeni JF. Splenectomy and subsequent mortality in veterans of the 1945 war. Lancet. 1977;310:127–9.CrossRef Robinette CD, Fraumeni JF. Splenectomy and subsequent mortality in veterans of the 1945 war. Lancet. 1977;310:127–9.CrossRef
9.
Zurück zum Zitat Fernández-Cruz L, Orduna D, Cesar-Borges G, Lopez-Boado MA. Distal pancreatectomy: en-bloc splenectomy vs. spleen-preserving pancreatectomy. HPB (Oxford). 2005;7:93–8. Fernández-Cruz L, Orduna D, Cesar-Borges G, Lopez-Boado MA. Distal pancreatectomy: en-bloc splenectomy vs. spleen-preserving pancreatectomy. HPB (Oxford). 2005;7:93–8.
10.
Zurück zum Zitat Govil S, Imrie CW. Value of splenic preservation during distal pancreatectomy for chronic pancreatitis. Br J Surg. 1999;86:895–8.CrossRefPubMed Govil S, Imrie CW. Value of splenic preservation during distal pancreatectomy for chronic pancreatitis. Br J Surg. 1999;86:895–8.CrossRefPubMed
11.
Zurück zum Zitat Hutchins RR, Hart RS, Pacifico M, Bradley NJ, Williamson RCN. Long-term results of distal pancreatectomy for chronic pancreatitis in 90 patients. Ann Surg. 2002;236:612–8.CrossRefPubMed Hutchins RR, Hart RS, Pacifico M, Bradley NJ, Williamson RCN. Long-term results of distal pancreatectomy for chronic pancreatitis in 90 patients. Ann Surg. 2002;236:612–8.CrossRefPubMed
12.
Zurück zum Zitat Schwarz RE, Harrison LE, Conlon KC, Klimstra DS, Brennan MF. The impact of splenectomy on outcomes after resection of pancreatic adenocarcinoma. J Am Coll Surg. 1999;188:516–21. Schwarz RE, Harrison LE, Conlon KC, Klimstra DS, Brennan MF. The impact of splenectomy on outcomes after resection of pancreatic adenocarcinoma. J Am Coll Surg. 1999;188:516–21.
13.
Zurück zum Zitat Mellemkjœr L, Olsen JH, Linet MS, Gridley G, McLaughlin JK. Cancer risk after splenectomy. Cancer. 1995;75:577–83.CrossRefPubMed Mellemkjœr L, Olsen JH, Linet MS, Gridley G, McLaughlin JK. Cancer risk after splenectomy. Cancer. 1995;75:577–83.CrossRefPubMed
14.
Zurück zum Zitat Warshaw AL. Conservation of the spleen with distal pancreatectomy. Arch Surg. 1988;123:550–3.PubMed Warshaw AL. Conservation of the spleen with distal pancreatectomy. Arch Surg. 1988;123:550–3.PubMed
15.
Zurück zum Zitat White SA, Sutton CD, Weymss-Holden S, Berry DP, Pollard C, Rees Y, et al. The feasibility of spleen-preserving pancreatectomy for end-stage chronic pancreatitis. Am J Surg. 2000;179:294–7.CrossRefPubMed White SA, Sutton CD, Weymss-Holden S, Berry DP, Pollard C, Rees Y, et al. The feasibility of spleen-preserving pancreatectomy for end-stage chronic pancreatitis. Am J Surg. 2000;179:294–7.CrossRefPubMed
16.
Zurück zum Zitat Romero-Torres R. The true splenic blood supply and its surgical applications. Hepatogastroenterology. 1998;45:885–8.PubMed Romero-Torres R. The true splenic blood supply and its surgical applications. Hepatogastroenterology. 1998;45:885–8.PubMed
17.
Zurück zum Zitat Rodriguez JR, Madanat MG, Healy BC, Thayer SP, Warshaw AL, Fernández-del Castillo C. Distal pancreatectomy with splenic preservation revisited. Surgery. 2007;141:619–25.CrossRefPubMed Rodriguez JR, Madanat MG, Healy BC, Thayer SP, Warshaw AL, Fernández-del Castillo C. Distal pancreatectomy with splenic preservation revisited. Surgery. 2007;141:619–25.CrossRefPubMed
18.
Zurück zum Zitat Mabrut JY, Fernández-Cruz L, Azagra JS, Bassi C, Delvaux G, Weerts J, et al. and Member Group under the auspices of the Hepatobiliary and Pancreatic Section of the Royal Belgian Society of Surgery, the Belgian Group for Endoscopic Surgery and the Club Coelio. Laparoscopic pancreatic resection: results of a multicenter European study of 127 patients. Surgery. 2005;137:597–605. Mabrut JY, Fernández-Cruz L, Azagra JS, Bassi C, Delvaux G, Weerts J, et al. and Member Group under the auspices of the Hepatobiliary and Pancreatic Section of the Royal Belgian Society of Surgery, the Belgian Group for Endoscopic Surgery and the Club Coelio. Laparoscopic pancreatic resection: results of a multicenter European study of 127 patients. Surgery. 2005;137:597–605.
19.
Zurück zum Zitat Fernández-Cruz L, Martínez I, Gilabert R, Cesar-Borges G, Astudillo E, Navarro S. Laparoscopic distal pancreatectomy combined with preservation of the spleen for cystic neoplasms of the pancreas. J Gastrointest Surg. 2004;8:493–501.CrossRefPubMed Fernández-Cruz L, Martínez I, Gilabert R, Cesar-Borges G, Astudillo E, Navarro S. Laparoscopic distal pancreatectomy combined with preservation of the spleen for cystic neoplasms of the pancreas. J Gastrointest Surg. 2004;8:493–501.CrossRefPubMed
20.
Zurück zum Zitat Sato Y, Shimoda S, Takeda N, Tanaka N, Hatakeyama K. Evaluation of splenic circulation after spleen-preserving distal pancreatectomy by dividing the splenic artery and vein. Dig Surg. 2000;17:519–22.CrossRefPubMed Sato Y, Shimoda S, Takeda N, Tanaka N, Hatakeyama K. Evaluation of splenic circulation after spleen-preserving distal pancreatectomy by dividing the splenic artery and vein. Dig Surg. 2000;17:519–22.CrossRefPubMed
21.
Zurück zum Zitat Aldridge MC, Williamson RCN. Distal pancreatectomy with and without splenectomy. Br J Surg. 1991;78:976–9.CrossRefPubMed Aldridge MC, Williamson RCN. Distal pancreatectomy with and without splenectomy. Br J Surg. 1991;78:976–9.CrossRefPubMed
22.
Zurück zum Zitat Miura F, Takada T, Asano T, Kenmochi T, Ochiai T, Amano H, et al. Hemodynamic changes of splenogastric circulation after spleen-preserving pancreatectomy with excision of splenic artery and vein. Surgery. 2005;138:518–22.CrossRefPubMed Miura F, Takada T, Asano T, Kenmochi T, Ochiai T, Amano H, et al. Hemodynamic changes of splenogastric circulation after spleen-preserving pancreatectomy with excision of splenic artery and vein. Surgery. 2005;138:518–22.CrossRefPubMed
23.
Zurück zum Zitat Miura F, Takada T, Asano T, Ochiai T. Gastric varices occurring after middle-segment pancreatectomy preserving spleen with division of splenic artery and vein. Surgery. 2004;135:696–7.CrossRefPubMed Miura F, Takada T, Asano T, Ochiai T. Gastric varices occurring after middle-segment pancreatectomy preserving spleen with division of splenic artery and vein. Surgery. 2004;135:696–7.CrossRefPubMed
Metadaten
Titel
Distal pancreatectomy with preservation of the spleen
verfasst von
Andrew L. Warshaw
Publikationsdatum
01.11.2010
Verlag
Springer Japan
Erschienen in
Journal of Hepato-Biliary-Pancreatic Sciences / Ausgabe 6/2010
Print ISSN: 1868-6974
Elektronische ISSN: 1868-6982
DOI
https://doi.org/10.1007/s00534-009-0226-z

Weitere Artikel der Ausgabe 6/2010

Journal of Hepato-Biliary-Pancreatic Sciences 6/2010 Zur Ausgabe

Update Chirurgie

Bestellen Sie unseren Fach-Newsletter und bleiben Sie gut informiert.

S3-Leitlinie „Diagnostik und Therapie des Karpaltunnelsyndroms“

CME: 2 Punkte

Prof. Dr. med. Gregor Antoniadis Das Karpaltunnelsyndrom ist die häufigste Kompressionsneuropathie peripherer Nerven. Obwohl die Anamnese mit dem nächtlichen Einschlafen der Hand (Brachialgia parästhetica nocturna) sehr typisch ist, ist eine klinisch-neurologische Untersuchung und Elektroneurografie in manchen Fällen auch eine Neurosonografie erforderlich. Im Anfangsstadium sind konservative Maßnahmen (Handgelenksschiene, Ergotherapie) empfehlenswert. Bei nicht Ansprechen der konservativen Therapie oder Auftreten von neurologischen Ausfällen ist eine Dekompression des N. medianus am Karpaltunnel indiziert.

Prof. Dr. med. Gregor Antoniadis
Berufsverband der Deutschen Chirurgie e.V.

S2e-Leitlinie „Distale Radiusfraktur“

CME: 2 Punkte

Dr. med. Benjamin Meyknecht, PD Dr. med. Oliver Pieske Das Webinar S2e-Leitlinie „Distale Radiusfraktur“ beschäftigt sich mit Fragen und Antworten zu Diagnostik und Klassifikation sowie Möglichkeiten des Ausschlusses von Zusatzverletzungen. Die Referenten erläutern, welche Frakturen konservativ behandelt werden können und wie. Das Webinar beantwortet die Frage nach aktuellen operativen Therapiekonzepten: Welcher Zugang, welches Osteosynthesematerial? Auf was muss bei der Nachbehandlung der distalen Radiusfraktur geachtet werden?

PD Dr. med. Oliver Pieske
Dr. med. Benjamin Meyknecht
Berufsverband der Deutschen Chirurgie e.V.

S1-Leitlinie „Empfehlungen zur Therapie der akuten Appendizitis bei Erwachsenen“

CME: 2 Punkte

Dr. med. Mihailo Andric
Inhalte des Webinars zur S1-Leitlinie „Empfehlungen zur Therapie der akuten Appendizitis bei Erwachsenen“ sind die Darstellung des Projektes und des Erstellungswegs zur S1-Leitlinie, die Erläuterung der klinischen Relevanz der Klassifikation EAES 2015, die wissenschaftliche Begründung der wichtigsten Empfehlungen und die Darstellung stadiengerechter Therapieoptionen.

Dr. med. Mihailo Andric
Berufsverband der Deutschen Chirurgie e.V.