Skip to main content
Erschienen in: Journal of Gastroenterology 4/2017

10.02.2017 | Review

Current status of achalasia management: a review on diagnosis and treatment

verfasst von: Joshua Tuason, Haruhiro Inoue

Erschienen in: Journal of Gastroenterology | Ausgabe 4/2017

Einloggen, um Zugang zu erhalten

Abstract

Background

Achalasia is a rare esophageal motility disorder that is characterized by loss of peristalsis and failure of relaxation of the lower esophageal sphincter (LES), particularly during swallowing. This review focuses on the diagnosis of esophageal motility disorders as defined by the Chicago Classification ver 3.0, and presents management options with regard to per-oral endoscopic myotomy (POEM) as the treatment of choice.

Methods

A concise review of literature was performed for articles related to the management of achalasia, and this was contrasted with our institution’s current practice.

Results

Achalasia is still incompletely understood, and management is focused on establishing a proper diagnosis, and relieving the obstructive symptoms.

Conclusions

Achalasia should be considered when dysphagia is present, and not otherwise caused by an obstruction or inflammation, and when criteria is met as per the Chicago Classification ver 3.0. Lowering LES tone and disruption of LES can be accomplished by various methods, most notably pneumatic balloon dilatation and surgical myotomy. POEM has been gaining momentum as a first line therapy for achalasia symptoms, and can be considered an important tool for motility disorders of the esophagus.
Literatur
2.
Zurück zum Zitat Cohen S, Parkman HP. Treatment of achalasia–whalebone to botulinum toxin. N Engl J Med. 1995;332:815–6.CrossRefPubMed Cohen S, Parkman HP. Treatment of achalasia–whalebone to botulinum toxin. N Engl J Med. 1995;332:815–6.CrossRefPubMed
3.
Zurück zum Zitat Vantrappen G, Hellemans J. Treatment of achalasia and related motor disorders. Gastroenterology. 1980;79:144–54.PubMed Vantrappen G, Hellemans J. Treatment of achalasia and related motor disorders. Gastroenterology. 1980;79:144–54.PubMed
4.
Zurück zum Zitat Park W, Vaezi MF. Etiology and pathogenesis of achalasia: the current understanding. Am J Gastroenterol. 2005;100:1404–14.CrossRefPubMed Park W, Vaezi MF. Etiology and pathogenesis of achalasia: the current understanding. Am J Gastroenterol. 2005;100:1404–14.CrossRefPubMed
5.
Zurück zum Zitat O’Neill OM, Johnston BT, Coleman HG. Achalasia: a review of clinical diagnosis, epidemiology, treatment and outcomes. World J Gastroenterol. 2013;19(35):5806–12.CrossRefPubMedPubMedCentral O’Neill OM, Johnston BT, Coleman HG. Achalasia: a review of clinical diagnosis, epidemiology, treatment and outcomes. World J Gastroenterol. 2013;19(35):5806–12.CrossRefPubMedPubMedCentral
6.
Zurück zum Zitat Sadowski DC, Ackah F, Jiang B, Svenson LW. Achalasia: incidence, prevalence and survival. A population-based study. Neurogastroenterol Motil. 2010;22:e256–61.CrossRefPubMed Sadowski DC, Ackah F, Jiang B, Svenson LW. Achalasia: incidence, prevalence and survival. A population-based study. Neurogastroenterol Motil. 2010;22:e256–61.CrossRefPubMed
7.
Zurück zum Zitat Francis DL, Katzka DA. Achalasia: an update on the disease and its treatment. Gastroenterology. 2010;139:369–74.CrossRefPubMed Francis DL, Katzka DA. Achalasia: an update on the disease and its treatment. Gastroenterology. 2010;139:369–74.CrossRefPubMed
8.
Zurück zum Zitat Winter H, Shukla R, Elshaer M, Riaz AA. Current management of achalasia—a review. Br J Med Pract. 2015;8(2):a810. Winter H, Shukla R, Elshaer M, Riaz AA. Current management of achalasia—a review. Br J Med Pract. 2015;8(2):a810.
9.
Zurück zum Zitat Pandolfino JE, Kwiatek MA, Nealis T, Bulsiewicz W, Post J, Kahrilas PJ. Achalasia: a new clinically relevant classification by high-resolution manometry. Gastroenterology. 2008;135:1526–33.CrossRefPubMedPubMedCentral Pandolfino JE, Kwiatek MA, Nealis T, Bulsiewicz W, Post J, Kahrilas PJ. Achalasia: a new clinically relevant classification by high-resolution manometry. Gastroenterology. 2008;135:1526–33.CrossRefPubMedPubMedCentral
10.
Zurück zum Zitat Sodikoff J, Lo A, Shetuni B, Kahrilas P, Yang G, Pandolfino JE. Histopathologic patterns across achalasia subtypes. Neurogastroenterol Motil. 2015;28:139–45.CrossRefPubMedPubMedCentral Sodikoff J, Lo A, Shetuni B, Kahrilas P, Yang G, Pandolfino JE. Histopathologic patterns across achalasia subtypes. Neurogastroenterol Motil. 2015;28:139–45.CrossRefPubMedPubMedCentral
11.
Zurück zum Zitat Singh R, Ghoshal UC, Misra A, Mittal B. Achalasia is associated with eNOS4a4a, iNOS22GA, and nNOS29TT genotypes: a case-control study. J Neurogastroenterol Motil. 2015;21:380–9.CrossRefPubMedPubMedCentral Singh R, Ghoshal UC, Misra A, Mittal B. Achalasia is associated with eNOS4a4a, iNOS22GA, and nNOS29TT genotypes: a case-control study. J Neurogastroenterol Motil. 2015;21:380–9.CrossRefPubMedPubMedCentral
12.
Zurück zum Zitat Shteyer E, Edvardson S, Wynia-Smith SL, Pierri CL, Zangen T, Hashavya S, Begin M, Yaacov B, et al. Truncating mutation in the nitric oxide synthase 1 gene is associated with infantile achalasia. Gastroenterology. 2015;148(533–6):e4. Shteyer E, Edvardson S, Wynia-Smith SL, Pierri CL, Zangen T, Hashavya S, Begin M, Yaacov B, et al. Truncating mutation in the nitric oxide synthase 1 gene is associated with infantile achalasia. Gastroenterology. 2015;148(533–6):e4.
13.
Zurück zum Zitat Vigo AG, Martinez A, de la Concha EG, Urcelay E, de Ruiz Leon A. Suggested association of NOS2A polymorphism in idiopathic achalasia: no evidence in a large case-control study. Am J Gastroenterol. 2009;104:1326–7.CrossRefPubMed Vigo AG, Martinez A, de la Concha EG, Urcelay E, de Ruiz Leon A. Suggested association of NOS2A polymorphism in idiopathic achalasia: no evidence in a large case-control study. Am J Gastroenterol. 2009;104:1326–7.CrossRefPubMed
14.
Zurück zum Zitat Goldblum JR, Rice TW, Richter JE. Histopathologic features in esophagomyotomy specimens from patients with achalasia. Gastroenterology. 1996;111:648–54.CrossRefPubMed Goldblum JR, Rice TW, Richter JE. Histopathologic features in esophagomyotomy specimens from patients with achalasia. Gastroenterology. 1996;111:648–54.CrossRefPubMed
15.
Zurück zum Zitat Minami H, Inoue H, Haji A, et al. Per-oral endoscopic myotomy: emerging indications and evolving techniques. Dig Endosc. 2015;26:175–81.CrossRef Minami H, Inoue H, Haji A, et al. Per-oral endoscopic myotomy: emerging indications and evolving techniques. Dig Endosc. 2015;26:175–81.CrossRef
16.
Zurück zum Zitat Friedel D, Modayil R, Stavropoulos SN. Per-oral endoscopic myotomy: major advance in achalasia treatment and in endoscopic surgery. World J Gastroenterol. 2014;20:17746–55.PubMedPubMedCentral Friedel D, Modayil R, Stavropoulos SN. Per-oral endoscopic myotomy: major advance in achalasia treatment and in endoscopic surgery. World J Gastroenterol. 2014;20:17746–55.PubMedPubMedCentral
17.
18.
Zurück zum Zitat Bogte A, Bredenoord AJ, Oors J, Siersema PD, Smout AJPM. Reproducibility of esophageal high-resolution manometry. Neurogastroenterol Motil. 2011;23(7):e271–6.CrossRefPubMed Bogte A, Bredenoord AJ, Oors J, Siersema PD, Smout AJPM. Reproducibility of esophageal high-resolution manometry. Neurogastroenterol Motil. 2011;23(7):e271–6.CrossRefPubMed
19.
Zurück zum Zitat Howard PJ, Maher L, Pryde A, et al. Five-year prospective study of the incidence, clinical features, and diagnosis of achalasia in Edinburgh. Gut. 1992;33:1011–5.CrossRefPubMedPubMedCentral Howard PJ, Maher L, Pryde A, et al. Five-year prospective study of the incidence, clinical features, and diagnosis of achalasia in Edinburgh. Gut. 1992;33:1011–5.CrossRefPubMedPubMedCentral
20.
Zurück zum Zitat Kumar P, Clark M. Clinical medicine. 4th ed. Edinburgh: WB Saunders; 1998. p. 229–31. Kumar P, Clark M. Clinical medicine. 4th ed. Edinburgh: WB Saunders; 1998. p. 229–31.
21.
Zurück zum Zitat Pohl D, Tutuian R. Achalasia: an overview of diagnosis and treatment. J Gastrointest Liver Dis. 2007;16(3):297–303. Pohl D, Tutuian R. Achalasia: an overview of diagnosis and treatment. J Gastrointest Liver Dis. 2007;16(3):297–303.
22.
Zurück zum Zitat Pandolfino JE, Ghosh SK, Rice J, Clarke JO, Kwiatek MA, Kahrilas PJ. Classifying esophageal motility by pressure topography characteristics: a study of 400 patients and 75 controls. Am J Gastroenterol. 2008;103(1):27–37.CrossRefPubMed Pandolfino JE, Ghosh SK, Rice J, Clarke JO, Kwiatek MA, Kahrilas PJ. Classifying esophageal motility by pressure topography characteristics: a study of 400 patients and 75 controls. Am J Gastroenterol. 2008;103(1):27–37.CrossRefPubMed
23.
Zurück zum Zitat Kahrilas PJ, Bredenoord AJ, Fox M, Gyawali CP, Roman S, Smout AJ, Pandolfino JE, IHRMWG. The Chicago Classification of esophageal motility disorders, v3.0. Neurogastroenterol Motil. 2015;27:160–74.CrossRefPubMed Kahrilas PJ, Bredenoord AJ, Fox M, Gyawali CP, Roman S, Smout AJ, Pandolfino JE, IHRMWG. The Chicago Classification of esophageal motility disorders, v3.0. Neurogastroenterol Motil. 2015;27:160–74.CrossRefPubMed
24.
Zurück zum Zitat McMahon BP, Frøkjær JB, Kunwald P, Liao D, et al. The functional lumen imaging probe (FLIP) for evaluation of the esophagogastric junction. Am J Physiol Gastrointest Liver Physiol. 2007;292:G377–84.CrossRefPubMed McMahon BP, Frøkjær JB, Kunwald P, Liao D, et al. The functional lumen imaging probe (FLIP) for evaluation of the esophagogastric junction. Am J Physiol Gastrointest Liver Physiol. 2007;292:G377–84.CrossRefPubMed
25.
Zurück zum Zitat Gyawali CP. Achalasia: new perspectives on an old disease. Neurogastroenterol Motil. 2016;28:4–11.CrossRefPubMed Gyawali CP. Achalasia: new perspectives on an old disease. Neurogastroenterol Motil. 2016;28:4–11.CrossRefPubMed
26.
Zurück zum Zitat Kwiatek MA, Pandolfino JE, Hirano I, Kahrilas PJ. Esophagogastric junction distensibility assessed with an endoscopic functional luminal imaging probe (EndoFLIP). Gastrointest Endosc. 2010;72(2):272–8.CrossRefPubMedPubMedCentral Kwiatek MA, Pandolfino JE, Hirano I, Kahrilas PJ. Esophagogastric junction distensibility assessed with an endoscopic functional luminal imaging probe (EndoFLIP). Gastrointest Endosc. 2010;72(2):272–8.CrossRefPubMedPubMedCentral
27.
28.
Zurück zum Zitat Vaezi MF, Pandolfino JE, Vela MF. ACG clinical guideline: diagnosis and management of achalasia. Am J Gastroenterol. 2013;108:1238–49.CrossRefPubMed Vaezi MF, Pandolfino JE, Vela MF. ACG clinical guideline: diagnosis and management of achalasia. Am J Gastroenterol. 2013;108:1238–49.CrossRefPubMed
29.
Zurück zum Zitat Pasricha PJ, Rai R, Ravich WJ, Hendrix TR, Kalloo AN. Botulinum toxin for achalasia: long-term outcome and predictors of response. Gastroenterology. 1996;110(5):1410–5.CrossRefPubMed Pasricha PJ, Rai R, Ravich WJ, Hendrix TR, Kalloo AN. Botulinum toxin for achalasia: long-term outcome and predictors of response. Gastroenterology. 1996;110(5):1410–5.CrossRefPubMed
30.
Zurück zum Zitat Lynch KL, Pandolfino JE, Howden CW, Kahrilas PJ. Major complications of pneumatic dilation and Heller myotomy for achalasia: single-center experience and systematic review of the literature. Am J Gastroenterol. 2012;107(12):1817–25.CrossRefPubMed Lynch KL, Pandolfino JE, Howden CW, Kahrilas PJ. Major complications of pneumatic dilation and Heller myotomy for achalasia: single-center experience and systematic review of the literature. Am J Gastroenterol. 2012;107(12):1817–25.CrossRefPubMed
31.
Zurück zum Zitat Ali A, Pellegrini CA. Laparoscopic myotomy: technique and efficacy in treating achalasia. Gastrointest Endosc Clin N Am. 2001;11:347–58.PubMed Ali A, Pellegrini CA. Laparoscopic myotomy: technique and efficacy in treating achalasia. Gastrointest Endosc Clin N Am. 2001;11:347–58.PubMed
32.
Zurück zum Zitat Campos GM, Vittinghoff E, Rabl C, et al. Endoscopic and surgical treatments for achalasia: a systematic review and meta-analysis. Ann Surg. 2009;249(1):45–57.CrossRefPubMed Campos GM, Vittinghoff E, Rabl C, et al. Endoscopic and surgical treatments for achalasia: a systematic review and meta-analysis. Ann Surg. 2009;249(1):45–57.CrossRefPubMed
33.
Zurück zum Zitat Richards WO, Torquati A, Holzman MD, et al. Heller myotomy versus Heller myotomy with Dor fundoplication for achalasia: a prospective randomized double-blind clinical trial. Ann Surg. 2004;240(3):405–12.CrossRefPubMedPubMedCentral Richards WO, Torquati A, Holzman MD, et al. Heller myotomy versus Heller myotomy with Dor fundoplication for achalasia: a prospective randomized double-blind clinical trial. Ann Surg. 2004;240(3):405–12.CrossRefPubMedPubMedCentral
34.
Zurück zum Zitat Rawlings A, Soper NJ, Oelschlager B, et al. Laparoscopic Dor versus Toupet fundoplication following Heller myotomy for achalasia: results of a multicenter, prospective, randomized-controlled trial. Surg Endosc. 2012;26(1):18–26.CrossRefPubMed Rawlings A, Soper NJ, Oelschlager B, et al. Laparoscopic Dor versus Toupet fundoplication following Heller myotomy for achalasia: results of a multicenter, prospective, randomized-controlled trial. Surg Endosc. 2012;26(1):18–26.CrossRefPubMed
35.
Zurück zum Zitat Persson J, Johnsson E, Kostic S, Lundell L, Smedh U. Treatment of achalasia with laparoscopic myotomy or pneumatic dilatation: long-term results of a prospective, randomized study. World J Surg. 2015;39(3):713–20.CrossRefPubMed Persson J, Johnsson E, Kostic S, Lundell L, Smedh U. Treatment of achalasia with laparoscopic myotomy or pneumatic dilatation: long-term results of a prospective, randomized study. World J Surg. 2015;39(3):713–20.CrossRefPubMed
36.
Zurück zum Zitat Novais PA, Lemme EMO. 24-h pH monitoring patterns and clinical response after achalasia treatment with pneumatic dilation or laparoscopic Heller myotomy. Aliment Pharmacol Ther. 2010;32(10):1257–65.CrossRefPubMed Novais PA, Lemme EMO. 24-h pH monitoring patterns and clinical response after achalasia treatment with pneumatic dilation or laparoscopic Heller myotomy. Aliment Pharmacol Ther. 2010;32(10):1257–65.CrossRefPubMed
37.
Zurück zum Zitat Boeckxstaens GE, Annese V, des Varannes SB, Chaussade S, Costantini M, Cuttitta A, Elizalde JI, Fumagalli U, et al. Pneumatic dilation versus laparoscopic Hellers myotomy for idiopathic achalasia. N Engl J Med. 2011;36:1807–16.CrossRef Boeckxstaens GE, Annese V, des Varannes SB, Chaussade S, Costantini M, Cuttitta A, Elizalde JI, Fumagalli U, et al. Pneumatic dilation versus laparoscopic Hellers myotomy for idiopathic achalasia. N Engl J Med. 2011;36:1807–16.CrossRef
38.
Zurück zum Zitat Vela MF, Richter JE, Khandwala F, et al. The long-term efficacy of pneumatic dilatation and Heller myotomy for the treatment of achalasia. Clin Gastroenterol Hepatol. 2006;4:580–7.CrossRefPubMed Vela MF, Richter JE, Khandwala F, et al. The long-term efficacy of pneumatic dilatation and Heller myotomy for the treatment of achalasia. Clin Gastroenterol Hepatol. 2006;4:580–7.CrossRefPubMed
39.
Zurück zum Zitat Gerson LB. Pneumatic dilation or myotomy for achalasia? Gastroenterology. 2007;132(2):811–3.CrossRefPubMed Gerson LB. Pneumatic dilation or myotomy for achalasia? Gastroenterology. 2007;132(2):811–3.CrossRefPubMed
40.
Zurück zum Zitat Inoue H, Minami H, Kobayashi Y, et al. Peroral endoscopic myotomy (POEM) for esophageal achalasia. Endoscopy. 2010;42(4):265–71.CrossRefPubMed Inoue H, Minami H, Kobayashi Y, et al. Peroral endoscopic myotomy (POEM) for esophageal achalasia. Endoscopy. 2010;42(4):265–71.CrossRefPubMed
41.
Zurück zum Zitat Pasricha PJ, Hawari R, Ahmed I, et al. Submucosal endoscopic esophageal myotomy: a novel experimental approach for the treatment of achalasia. Endoscopy. 2007;39:761–4.CrossRefPubMed Pasricha PJ, Hawari R, Ahmed I, et al. Submucosal endoscopic esophageal myotomy: a novel experimental approach for the treatment of achalasia. Endoscopy. 2007;39:761–4.CrossRefPubMed
42.
Zurück zum Zitat Ujiki MB, Yetasook AK, Zapf M, Linn JG, Carbray JM, Denham W. Peroral endoscopic myotomy: a short-term comparison with the standard laparoscopic approach. Surgery. 2013;154(4):893–7.CrossRefPubMed Ujiki MB, Yetasook AK, Zapf M, Linn JG, Carbray JM, Denham W. Peroral endoscopic myotomy: a short-term comparison with the standard laparoscopic approach. Surgery. 2013;154(4):893–7.CrossRefPubMed
43.
Zurück zum Zitat Von Renteln D, Inoue H, Minami H. Peroral endoscopic myotomy for the treatment of achalasia: a prospective single center study. Am J Gastroenterol. 2012;107:411–7.CrossRef Von Renteln D, Inoue H, Minami H. Peroral endoscopic myotomy for the treatment of achalasia: a prospective single center study. Am J Gastroenterol. 2012;107:411–7.CrossRef
44.
Zurück zum Zitat Von Renteln D, Fuchs KH, Fockens P. Peroral endoscopic myotomy for the treatment of achalasia: an international prospective multicenter study. Gastroenterology. 2013;145:309–11.CrossRef Von Renteln D, Fuchs KH, Fockens P. Peroral endoscopic myotomy for the treatment of achalasia: an international prospective multicenter study. Gastroenterology. 2013;145:309–11.CrossRef
45.
Zurück zum Zitat Patel K, Abbassi-Ghadi N, Markar S, Kumar S, Jethwa P, Zaninotto G. Peroral endoscopic myotomy for the treatment of esophageal achalasia: systematic review and pooled analysis. Dis Esophagus. 2016;29:807–19. doi:10.1111/dote.12387.CrossRefPubMed Patel K, Abbassi-Ghadi N, Markar S, Kumar S, Jethwa P, Zaninotto G. Peroral endoscopic myotomy for the treatment of esophageal achalasia: systematic review and pooled analysis. Dis Esophagus. 2016;29:807–19. doi:10.​1111/​dote.​12387.CrossRefPubMed
46.
Zurück zum Zitat Inoue H, Tianle KM, Ikeda H, et al. Peroral endoscopic myotomy for esophageal achalasia: technique, indication, and outcomes. Thorac Surg Clin. 2011;21:519–25.CrossRefPubMed Inoue H, Tianle KM, Ikeda H, et al. Peroral endoscopic myotomy for esophageal achalasia: technique, indication, and outcomes. Thorac Surg Clin. 2011;21:519–25.CrossRefPubMed
47.
Zurück zum Zitat Bechara R, Onimaru M, Ikeda H, et al. Per-oral endoscopic myotomy, 1000 cases later: pearls, pitfalls, and practical considerations. Gastrointest Endosc. 2016;84(2):330–8.CrossRefPubMed Bechara R, Onimaru M, Ikeda H, et al. Per-oral endoscopic myotomy, 1000 cases later: pearls, pitfalls, and practical considerations. Gastrointest Endosc. 2016;84(2):330–8.CrossRefPubMed
48.
Zurück zum Zitat Balassone V, Ikeda H, Kazuya S, et al. Peroral endoscopic myotomy: first human experience with a water-jet-assisted triangle knife. Gastrointest Endosc. (Epub 2016 May 6). Balassone V, Ikeda H, Kazuya S, et al. Peroral endoscopic myotomy: first human experience with a water-jet-assisted triangle knife. Gastrointest Endosc. (Epub 2016 May 6).
49.
Zurück zum Zitat Grimes KL, Inoue H, Onimaru M, et al. Double-scope per oral endoscopic myotomy (POEM): a prospective randomized controlled trial. Surg Endosc. 2016;30:1344–51.CrossRefPubMed Grimes KL, Inoue H, Onimaru M, et al. Double-scope per oral endoscopic myotomy (POEM): a prospective randomized controlled trial. Surg Endosc. 2016;30:1344–51.CrossRefPubMed
50.
Zurück zum Zitat Youn YH, Minami H, Chiu PW, Park H. Peroral endoscopic myotomy for treating achalasia and esophageal motility disorders. J Neurogastroenterol Motil. 2016;22:14–24.CrossRefPubMedPubMedCentral Youn YH, Minami H, Chiu PW, Park H. Peroral endoscopic myotomy for treating achalasia and esophageal motility disorders. J Neurogastroenterol Motil. 2016;22:14–24.CrossRefPubMedPubMedCentral
51.
Zurück zum Zitat Shiwaku H, Inoue H, Beppu R, et al. Successful treatment of diffuse esophageal spasm by peroral endoscopic myotomy. Gastrointest Endosc. 2013;77:149–50.CrossRefPubMed Shiwaku H, Inoue H, Beppu R, et al. Successful treatment of diffuse esophageal spasm by peroral endoscopic myotomy. Gastrointest Endosc. 2013;77:149–50.CrossRefPubMed
52.
Zurück zum Zitat Ling T, Guo H, Zou X. Effect of peroral endoscopic myotomy in achalasia patients with failure of prior pneumatic dilation: a prospective case-control study. J Gastroenterol Hepatol. 2014;29:1609–13.CrossRefPubMed Ling T, Guo H, Zou X. Effect of peroral endoscopic myotomy in achalasia patients with failure of prior pneumatic dilation: a prospective case-control study. J Gastroenterol Hepatol. 2014;29:1609–13.CrossRefPubMed
53.
Zurück zum Zitat Zhou PH, Li QL, Yao LQ, et al. Peroral endoscopic remyotomy for failed Heller myotomy: a prospective single-center study. Endoscopy. 2013;45:161–6.CrossRefPubMed Zhou PH, Li QL, Yao LQ, et al. Peroral endoscopic remyotomy for failed Heller myotomy: a prospective single-center study. Endoscopy. 2013;45:161–6.CrossRefPubMed
54.
Zurück zum Zitat Onimaru M, Inoue H, Ikeda H, et al. Peroral endoscopic myotomy is a viable option for failed surgical esophagocardiomyotomy instead of redo surgical Heller myotomy: a single center prospective study. J Am Coll Surg. 2013;217:598–605.CrossRefPubMed Onimaru M, Inoue H, Ikeda H, et al. Peroral endoscopic myotomy is a viable option for failed surgical esophagocardiomyotomy instead of redo surgical Heller myotomy: a single center prospective study. J Am Coll Surg. 2013;217:598–605.CrossRefPubMed
55.
Zurück zum Zitat Vigneswaran Y, Yetasook AK, Zhao JC, Denham W, Linn JG, Ujiki MB. Peroral endoscopic myotomy (POEM): feasible as reoperation following Heller myotomy. J Gastrointest Surg. 2014;18:1071–6.CrossRefPubMed Vigneswaran Y, Yetasook AK, Zhao JC, Denham W, Linn JG, Ujiki MB. Peroral endoscopic myotomy (POEM): feasible as reoperation following Heller myotomy. J Gastrointest Surg. 2014;18:1071–6.CrossRefPubMed
56.
Zurück zum Zitat Inoue H, Sato H, Ikeda H, Onimaru M, et al. Per-oral endoscopic myotomy: a series of 500 patients. J Am Coll Surg. 2015;221:256–64.CrossRefPubMed Inoue H, Sato H, Ikeda H, Onimaru M, et al. Per-oral endoscopic myotomy: a series of 500 patients. J Am Coll Surg. 2015;221:256–64.CrossRefPubMed
57.
Zurück zum Zitat Marano L, Pallabazzer G, Solito B, Santi S, Pigazzi A, De Luca R, Biondo FG, Spaziani A, Longaroni M, Di Martino N, et al. Surgery or peroral esophageal myotomy for achalasia: a systematic review and meta-analysis. Med (Baltimore). 2016;95:e3001.CrossRef Marano L, Pallabazzer G, Solito B, Santi S, Pigazzi A, De Luca R, Biondo FG, Spaziani A, Longaroni M, Di Martino N, et al. Surgery or peroral esophageal myotomy for achalasia: a systematic review and meta-analysis. Med (Baltimore). 2016;95:e3001.CrossRef
58.
Zurück zum Zitat Talukdar R, Inoue H, Reddy DN. Efficacy of peroral endoscopic myotomy (POEM) in the treatment of achalasia: a systematic review and meta-analysis. Surg Endosc. 2015;29(11):3030–46.CrossRefPubMed Talukdar R, Inoue H, Reddy DN. Efficacy of peroral endoscopic myotomy (POEM) in the treatment of achalasia: a systematic review and meta-analysis. Surg Endosc. 2015;29(11):3030–46.CrossRefPubMed
59.
Zurück zum Zitat Chan SM, Wu JC, Teoh AY, et al. Comparison of early outcomes and quality of life after laparoscopic Heller’s cardiomyotomy to peroral endoscopic myotomy for treatment of achalasia. Dig Endosc. 2016;28(1):27–32.CrossRefPubMed Chan SM, Wu JC, Teoh AY, et al. Comparison of early outcomes and quality of life after laparoscopic Heller’s cardiomyotomy to peroral endoscopic myotomy for treatment of achalasia. Dig Endosc. 2016;28(1):27–32.CrossRefPubMed
60.
Zurück zum Zitat Sanaka MR, Hayat U, Thota PN, et al. Efficacy of peroral endoscopic myotomy vs other achalasia treatments in improving esophageal function. World J Gastroenterol. 2016;22(20):4918–25.CrossRefPubMedPubMedCentral Sanaka MR, Hayat U, Thota PN, et al. Efficacy of peroral endoscopic myotomy vs other achalasia treatments in improving esophageal function. World J Gastroenterol. 2016;22(20):4918–25.CrossRefPubMedPubMedCentral
61.
Zurück zum Zitat Stavropoulos SN, Modayil R, Friedel D, et al. The international per oral endoscopic myotomy survey (IPOEMS): a snapshot of the global POEM experience. Surg Endosc. 2013;27(9):3322–38.CrossRefPubMed Stavropoulos SN, Modayil R, Friedel D, et al. The international per oral endoscopic myotomy survey (IPOEMS): a snapshot of the global POEM experience. Surg Endosc. 2013;27(9):3322–38.CrossRefPubMed
62.
Zurück zum Zitat Stavropoulos SN, Desilets DJ, Fuchs KH, et al. Per-oral endoscopic myotomy white paper summary. Gastrointest Endosc. 2014;80(1):1–15.CrossRefPubMed Stavropoulos SN, Desilets DJ, Fuchs KH, et al. Per-oral endoscopic myotomy white paper summary. Gastrointest Endosc. 2014;80(1):1–15.CrossRefPubMed
63.
Zurück zum Zitat Swanstrom LL, Kurian A, Dunst CM, Sharata A, Bhayani N, Rieder E. Long-term outcomes of an endoscopic myotomy for achalasia: the POEM procedure. Ann Surg. 2012;256(4):659–67.CrossRefPubMed Swanstrom LL, Kurian A, Dunst CM, Sharata A, Bhayani N, Rieder E. Long-term outcomes of an endoscopic myotomy for achalasia: the POEM procedure. Ann Surg. 2012;256(4):659–67.CrossRefPubMed
Metadaten
Titel
Current status of achalasia management: a review on diagnosis and treatment
verfasst von
Joshua Tuason
Haruhiro Inoue
Publikationsdatum
10.02.2017
Verlag
Springer Japan
Erschienen in
Journal of Gastroenterology / Ausgabe 4/2017
Print ISSN: 0944-1174
Elektronische ISSN: 1435-5922
DOI
https://doi.org/10.1007/s00535-017-1314-5

Weitere Artikel der Ausgabe 4/2017

Journal of Gastroenterology 4/2017 Zur Ausgabe

Leitlinien kompakt für die Innere Medizin

Mit medbee Pocketcards sicher entscheiden.

Seit 2022 gehört die medbee GmbH zum Springer Medizin Verlag

Update Innere Medizin

Bestellen Sie unseren Fach-Newsletter und bleiben Sie gut informiert.