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Comparative Clinical Pathology

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01.01.2016 | Brief Communication

Follicular adenoma associated with spindle cell proliferation, papillary adenoma and colloid goitre in a dromedary camel

verfasst von: Mohamed H. Tageldin, Hassan Abu Damir, Elhag A. Omer, Mahmoud A. Ali, Adam M. Adam

Erschienen in: Comparative Clinical Pathology | Ausgabe 1/2016

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Abstract

In humans, spindle cell lesions associated with thyroid adenoma or carcinoma are rare. A cross section of the thyroid of a dromedary camel showed follicular cysts, and microscopically, both thyroid lobes showed colloid goitre. The left lobe showed spindle cell proliferation associated with follicular adenoma without evidence of capsular or vascular invasion. The spindle cell lesion had cells featuring ground glass or pseudoinclusion nuclei and showed extensive haemorrhage, hyalinization and thrombosis. The right thyroid lobe showed papillary adenoma. Immunohistochemistry showed negative expression for malignancy. Serum Se, free tri-iodothyronine (fT3) and free thyroxine (fT4) values were low and CK activity was high. The histological features were unusual and merit reporting.

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Titel: Follicular adenoma associated with spindle cell proliferation, papillary adenoma and colloid goitre in a dromedary camel
verfasst von: Mohamed H. Tageldin
Hassan Abu Damir
Elhag A. Omer
Mahmoud A. Ali
Adam M. Adam
Publikationsdatum: 01.01.2016
Verlag: Springer London
Erschienen in: Comparative Clinical Pathology / Ausgabe 1/2016
Print ISSN: 1618-5641
Elektronische ISSN: 1618-565X
DOI: https://doi.org/10.1007/s00580-015-2183-z

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