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Course and Prognostic Factors for Neck Pain in Whiplash-Associated Disorders (WAD)

Results of the Bone and Joint Decade 2000-2010 Task Force on Neck Pain and Its Associated Disorders

  • Best Evidence
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European Spine Journal Aims and scope Submit manuscript

Study Design

Best evidence synthesis.

Objective

To perform a best evidence synthesis on the course and prognostic factors for neck pain and its associated disorders in Grades I–III whiplash-associated disorders (WAD).

Summary of Background Data

Knowledge of the course of recovery of WAD guides expectations for recovery. Identifying prognostic factors assists in planning management and intervention strategies and effective compensation policies to decrease the burden of WAD.

Methods

The Bone and Joint Decade 2000–2010 Task Force on Neck Pain and its Associated Disorders (Neck Pain Task Force) conducted a critical review of the literature published between 1980 and 2006 to assemble the best evidence on neck pain and its associated disorders. Studies meeting criteria for scientific validity were included in a best evidence synthesis.

Results

We found 226 articles related to course and prognostic factors in neck pain and its associated disorders. After a critical review, 70 (31%) were accepted on scientific merit; 47 of these studies related to course and prognostic factors in WAD. The evidence suggests that approximately 50% of those with WAD will report neck pain symptoms 1 year after their injuries. Greater initial pain, more symptoms, and greater initial disability predicted slower recovery. Few factors related to the collision itself (for example, direction of the collision, headrest type) were prognostic; however, postinjury psychological factors such as passive coping style, depressed mood, and fear of movement were prognostic for slower or less complete recovery. There is also preliminary evidence that the prevailing compensation system is prognostic for recovery in WAD.

Conclusion

The Neck Pain Task Force undertook a best evidence synthesis to establish a baseline of the current best evidence on the course and prognosis for WAD. Recovery of WAD seems to be multifactorial.

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References

  1. Holm LW, Carroll LJ, Cassidy JD, et al. (2008) The burden and determinants of neck pain in whiplash-associated disorders after traffic collisions. Results of the Bone and Joint Decade 2000–2010 Task Force on Neck Pain and Its Associated Disorders. Spine 33(Suppl):S52–S59

    Article  PubMed  Google Scholar 

  2. Spitzer WO, Skovron ML, Salmi LR, et al. (1995) Scientific monograph of the Quebec Task Force on Whiplash-Associated Disorders: redefining “whiplash” and its management. Spine 20:1S–73S

    PubMed  CAS  Google Scholar 

  3. Altman DG, Lymann GH. (1998) Methodological challenges in the evaluation of prognostic factors in breast cancer. Breast Cancer Res Treat 52:289–303

    Article  PubMed  CAS  Google Scholar 

  4. Carroll LJ, Cassidy JD, Côté P. (2004) Depression as a risk factor for onset of an episode of troublesome neck and low back pain. Pain 107:134–9

    Article  PubMed  Google Scholar 

  5. Carroll LJ, Cassidy JD, Peloso PM, et al. (2004) Prognosis for mild traumatic brain injury: results of the WHO Collaborating Centre Task Force on Mild Traumatic Brain Injury. J Rehabil Med 43:84–105

    Article  PubMed  Google Scholar 

  6. Côté P, Cassidy JD, Carroll L, et al. (2001) A systematic review of the prognosis of acute whiplash and a new conceptual framework to synthesize the literature. Spine 26:E445–E458

    Article  PubMed  Google Scholar 

  7. Carroll LJ, Hogg-Johnson S, van der Velde G, et al. (2008) Course and prognostic factors for neck pain in the general population. Results of the Bone and Joint Decade 2000–2010 Task Force on Neck Pain and Its Associated Disorders. Spine 33(Suppl):S75–S82

    Article  PubMed  Google Scholar 

  8. Carroll LJ, Hogg-Johnson S, Côté P, et al. (2008) Course and prognostic factors for neck pain in workers. Results of the Bone and Joint Decade 2000–2010 Task Force on Neck Pain and Its Associated Disorders. Spine 33(Suppl):S93–S100

    PubMed  Google Scholar 

  9. Carroll LJ, Cassidy JD, Peloso PM, et al. (2008) Methods for the best evidence synthesis on neck pain and its associated disorders. The Bone and Joint Decade 2000–2010 Task Force on Neck Pain and Its Associated Disorders. Spine 33(Suppl):S33–S38

    PubMed  Google Scholar 

  10. Slavin RE. (1986) Best evidence synthesis: an alternative to meta-analytic and traditional reviews. Educ Res 15:5–11

    Google Scholar 

  11. Slavin RE. (1995) Best evidence synthesis: an intelligent alternative to meta-analysis. J Clin Epidemiol 48:9–18

    Article  PubMed  CAS  Google Scholar 

  12. van der Velde G, van Tulder M, Côté P, et al. (2007) The sensitivity of review results to methods used to appraise and incorporate trial quality into data synthesis. Spine 32:796–806

    Article  PubMed  Google Scholar 

  13. Guzman J, Hurwitz EL, Carroll LJ, et al. (2008) A conceptual model for the course and care of neck pain Results of The Bone and Joint Decade 2000–2010 Task Force on Neck Pain and Its Associated Disorders. Spine 33(Suppl):S14–S23

    PubMed  Google Scholar 

  14. Côté P, van der Velde G, Cassidy JD, et al. (2008) The burden and determinants of neck pain in workers. Results of the Bone and Joint 2000–2010 Task Force on Neck Pain and Its Associated Disorders. Spine 33(Suppl):S60–S74

    Article  PubMed  Google Scholar 

  15. Hogg-Johnson S, van der Velde G, Carroll LJ, et al. (2008) The burden and determinants of neck pain in the general population. Results of the Bone and Joint Decade 2000–2010 Task Force on Neck Pain and Its Associated Disorders. Spine 33(Suppl):S39–S51

    PubMed  Google Scholar 

  16. World Health Organization. International Classification of Function, Disability and Health: ICF. Geneva: WHO; 2001.

  17. Berglund A, Alfredsson L, Cassidy JD, et al. (2000) The association between exposure to a rear-end collision and future neck or shoulder pain: a cohort study. J Clin Epidemiol 53:1089–94

    Article  PubMed  CAS  Google Scholar 

  18. Borchgrevink GE, Lereim I, Royneland L, et al. (1996) National health insurance consumption and chronic symptoms following mild neck sprain injuries in car collisions. Scand J Soc Med 24:264–71

    PubMed  CAS  Google Scholar 

  19. Boyd R, Massey R, Duane L, et al. (2002) Whiplash associated disorder in children attending the emergency department. Emerg Med J 19:311–4

    Article  PubMed  CAS  Google Scholar 

  20. Bylund PO, Bjornstig U. (1998) Sick leave and disability pension among passenger car occupants injured in urban traffic. Spine 23:1023–8

    Article  PubMed  CAS  Google Scholar 

  21. Cassidy JD, Carroll LJ, Côté P, et al. (2000) Effect of eliminating compensation for pain and suffering on the outcome of insurance claims for whiplash injury. N Engl J Med 342:1179–86

    Article  PubMed  CAS  Google Scholar 

  22. Cassidy JD, Carroll LJ, Côté P, et al. (2007) Does multidisciplinary rehabilitation benefit whiplash recovery?. Results of a population-based incidence cohort study. Spine 32:126–31

    Article  PubMed  Google Scholar 

  23. Drottning M, Staff PH, Sjaastad O. (2002) Cervicogenic headache (CEH) after whiplash injury. Cephalalgia 22:165–71

    Article  PubMed  CAS  Google Scholar 

  24. Gargan M, Bannister G, Main C, et al. (1997) The behavioural response to whiplash injury. J Bone Joint Surg Br 79:523–6

    Article  PubMed  CAS  Google Scholar 

  25. Holm L, Cassidy JD, Sjogren Y, et al. (1999) Impairment and work disability due to whiplash injury following traffic collisions. An analysis of insurance material from the Swedish Road Traffic Injury Commission. Scand J Public Health 27:116–23

    CAS  Google Scholar 

  26. Jonsson H, Cesarini K, Sahlstedt B, et al. (1994) Findings and outcome in whiplashtype neck distortions. Spine 19:2733–43

    Article  PubMed  Google Scholar 

  27. Kasch H, Bach FW, Stengaard-Pedersen K, et al. (2003) Development in pain and neurologic complaints after whiplash: a 1-year prospective study. Neurology 60:743–9

    PubMed  Google Scholar 

  28. Mayou R, Bryant B. (2002) Psychiatry of whiplash neck injury. Br J Psychiatry 180:441–8

    Article  PubMed  Google Scholar 

  29. Norris SH, Watt I. (1983) The prognosis of neck injuries resulting from rear-end vehicle collisions. J Bone Joint Surg Br 65:608–11

    PubMed  CAS  Google Scholar 

  30. Obelieniene D, Schrader H, Bovim G, et al. (1999) Pain after whiplash: a prospective controlled inception cohort study. J Neurol Neurosurg Psychiatry 66: 279–83

    PubMed  CAS  Google Scholar 

  31. Partheni M, Constantoyannis C, Ferrari R, et al. (2000) A prospective cohort study of the outcome of acute whiplash injury in Greece. Clin Exp Rheumatol 18:67–70

    PubMed  CAS  Google Scholar 

  32. Sterling M, Jull G, Vicenzino B, et al. (2003) Development of motor system dysfunction following whiplash injury. Pain 103:65–73

    Article  PubMed  Google Scholar 

  33. Suissa S, Giroux M, Gervais M, et al. (2006) Assessing a whiplash management model: a population-based non-randomized intervention study. J Rheumatol 33:581–7

    PubMed  Google Scholar 

  34. Miettinen T, Airaksinen O, Lindgren KA, et al. (2004) Whiplash injuries in Finland–the possibility of some sociodemographic and psychosocial factors to predict the outcome after one year. Disabil Rehabil 26:1367–72

    Article  PubMed  Google Scholar 

  35. Miettinen T, Leino E, Airaksinen O, et al. (2004) Whiplash injuries in Finland: the situation 3 years later. Eur Spine J 13:415–8

    Article  PubMed  Google Scholar 

  36. Suissa S, Harder S, Veilleux M. (1995) The Quebec whiplash-associated disorders cohort study. Spine 20:12S–20S

    Google Scholar 

  37. Gargan MF, Bannister GC. (1994) The rate of recovery following whiplash injury. Eur Spine J 3:162–4

    Article  PubMed  CAS  Google Scholar 

  38. Berglund A, Alfredsson L, Jensen I, et al. (2001) The association between exposure to a rear-end collision and future health complaints. J Clin Epidemiol 54:851–6

    Article  PubMed  CAS  Google Scholar 

  39. Berglund A, Bodin L, Jensen I, et al. (2006) The influence of prognostic factors on neck pain intensity, disability, anxiety and depression over a 2-year period in subjects with acute whiplash injury. Pain 125:244–56

    Article  PubMed  Google Scholar 

  40. Harder S, Veilleux M, Suissa S. (1998) The effect of socio-demographic and crashrelated factors on the prognosis of whiplash. J Clin Epidemiol 51: 377–84

    Article  PubMed  CAS  Google Scholar 

  41. Sterner Y, Toolanen G, Gerdle B, et al. (2003) The incidence of whiplash trauma and the effects of different factors on recovery. J Spinal Disord Tech 16:195–9

    PubMed  Google Scholar 

  42. Hartling L, Pickett W, Brison RJ. (2002) Derivation of a clinical decision rule for whiplash associated disorders among individuals involved in rear-end collisions. Accid Anal Prev 34:531–9

    Article  PubMed  Google Scholar 

  43. Kasch H, Bach FW, Jensen TS. (2001) Handicap after acute whiplash injury: a 1-year prospective study of risk factors. Neurology 56:1637–43

    PubMed  CAS  Google Scholar 

  44. Kivioja J, Jensen I, Lindgren U. (2005) Early coping strategies do not influence the prognosis after whiplash injuries. Injury 36:935–40

    Article  PubMed  Google Scholar 

  45. Richter M, Ferrari R, Otte D, et al. (2004) Correlation of clinical findings, collision parameters, and psychological factors in the outcome of whiplash associated disorders. J Neurol Neurosurg Psychiatry 75:758–64

    Article  PubMed  CAS  Google Scholar 

  46. Krafft M, Kullgren A, Tingvall C, et al. (2000) How crash severity in rear impacts influences short- and long-term consequences to the neck. Accid Anal Prev 32:187–95

    Article  PubMed  CAS  Google Scholar 

  47. Krafft M, Kullgren A, Ydenius A, et al. (2002) Influence of crash pulse characteristics on whiplash associated disorders in rear impacts – crash recording in real life crashes. Traffic Inj Prev 3:141–9

    Article  Google Scholar 

  48. Nordin M, Carragee EJ, Hogg-Johnson S, et al. (2008) Assessment of neck pain and its associated disorders. Results of the Bone and Joint Decade 2000–2010 Task Force on Neck Pain and Its Associated Disorders. Spine 33(Suppl):S101–S122

    PubMed  Google Scholar 

  49. Nederhand MJ, Hermens HJ, IJzerman MJ, et al. (2003) Chronic neck pain disability due to an acute whiplash injury. Pain 102:63–71

    Article  PubMed  Google Scholar 

  50. Nederhand MJ, IJzerman MJ, Hermens HJ, et al. (2004) Predictive value of fear avoidance in developing chronic neck pain disability: consequences for clinical decision making. Arch Phys Med Rehabil 85:496–501

    Article  PubMed  Google Scholar 

  51. Suissa S, Harder S, Veilleux M. (2001) The relation between initial symptoms and signs and the prognosis of whiplash. Eur Spine J 10:44–9

    Article  PubMed  CAS  Google Scholar 

  52. Suissa S. (2003) Risk factors of poor prognosis after whiplash injury. Pain Res Manag 8:69–75

    PubMed  Google Scholar 

  53. Carroll LJ, Cassidy JD, Côté P. (2006) The role of pain coping strategies in prognosis after whiplash injury: passive coping predicts slowed recovery. Pain 124:18–26

    Article  PubMed  Google Scholar 

  54. Côté P, Hogg-Johnson S, Cassidy JD, et al. (2001) The association between neck pain intensity, physical functioning, depressive symptomatology and timeto-claim-closure after whiplash. J Clin Epidemiol 54:275–86

    Article  PubMed  Google Scholar 

  55. Hurwitz EL, Carragee EJ, van der Velde G, et al. (2008) Treatment of neck pain: non-invasive interventions. Results of the Bone and Joint Decade 2000–2010 Task Force on Neck Pain and its Associated Disorders. Spine 33(Suppl):S123–S152

    PubMed  Google Scholar 

  56. Côté P, Hogg-Johnson S, Cassidy JD, et al. (2007) Early aggressive care and delayed recovery from whiplash: isolated finding or reproducible results?. Arthritis Care Res 57:861–8

    Article  Google Scholar 

  57. Côté P, Hogg-Johnson S, Cassidy JD, et al. (2005) Initial patterns of clinical care and recovery from whiplash injuries: a population-based cohort study. Arch Intern Med 165:2257–63

    Article  PubMed  Google Scholar 

  58. Kasch H, Stengaard-Pedersen K, Arendt-Nielsen L, et al. (2001) Pain thresholds and tenderness in neck and head following acute whiplash injury: a prospective study. Cephalalgia 21:189–97

    Article  PubMed  CAS  Google Scholar 

  59. Kasch H, Qerama E, Bach FW, et al. (2005) Reduced cold pressor pain tolerance in non-recovered whiplash patients: a 1-year prospective study. Eur J Pain 9:561–9

    Article  PubMed  Google Scholar 

  60. Buskila D, Neumann L, Vaisberg G, et al. (1997) Increased rates of fibromyalgia following cervical spine injury. A controlled study of 161 cases of traumatic injury. Arthritis Rheum 40:446–52

    Article  PubMed  CAS  Google Scholar 

  61. Holm LW, Carroll LJ, Cassidy JD, et al. (2007) Widespread pain following whiplash-associated disorders: incidence, course, and risk factors. J Rheumatol 34:193–200

    PubMed  Google Scholar 

  62. Wynne-Jones G, Jones GT, Wiles NJ, et al. (2006) Predicting new onset of widespread pain following a motor vehicle collision. J Rheumatol 33: 968–74

    PubMed  Google Scholar 

  63. Carroll LJ, Cassidy JD, Côté P. (2006) Frequency, timing, and course of depressive symptomatology after whiplash. Spine 31:E551–E556

    Article  PubMed  Google Scholar 

  64. Ferrari R, Obelieniene D, Russel AS, et al. (2002) Laypersons’ expectation of the sequelae of whiplash injury. A cross-cultural comparative study between Canada and Lithuania. Med Sci Monit 8:CR728–CR734

    PubMed  Google Scholar 

  65. Ferrari R, Lang C. (2005) A cross-cultural comparison between Canada and Germany of symptom expectations for whiplash injury. J Spinal Disord Tech 18:92–7

    Article  PubMed  Google Scholar 

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Correspondence to Linda J. Carroll PhD.

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The manuscript submitted does not contain information about medical device(s)/drug(s).

Corporate/Industry, Foundation, and Professional Organizational funds were received in support of this work. No benefits in any form have been or will be received from a commercial party related directly or indirectly to the subject of this manuscript.

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Carroll, L.J., Holm, L.W., Hogg-Johnson, S. et al. Course and Prognostic Factors for Neck Pain in Whiplash-Associated Disorders (WAD). Eur Spine J 17 (Suppl 1), 83–92 (2008). https://doi.org/10.1007/s00586-008-0628-7

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  • DOI: https://doi.org/10.1007/s00586-008-0628-7

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