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Erschienen in: European Spine Journal 4/2008

01.12.2008 | Review

Tissue engineering and the intervertebral disc: the challenges

verfasst von: Rita Kandel, Sally Roberts, Jill P. G. Urban

Erschienen in: European Spine Journal | Sonderheft 4/2008

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Abstract

Disc degeneration is a common disorder. Although the back pain that can develop in association with this is rarely life-threatening, the annual cost in terms of morbidity, lost productivity, medical expenses and workers’ compensation benefits is significant. Surgical intervention as practised currently is directed towards removing the damaged or altered tissue. Development of new treatment modalities is critical as there is a growing consensus that the strategies used currently for symptomatic degenerative disc disease may not be effective. Accordingly, there is a need to develop an entirely new way to treat this disorder; regenerative medicine and tissue engineering approaches appear particularly promising in this regard. This paper reviews some of the challenges that currently are limiting the clinical application of this approach to the treatment of disc degeneration.
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Metadaten
Titel
Tissue engineering and the intervertebral disc: the challenges
verfasst von
Rita Kandel
Sally Roberts
Jill P. G. Urban
Publikationsdatum
01.12.2008
Verlag
Springer-Verlag
Erschienen in
European Spine Journal / Ausgabe Sonderheft 4/2008
Print ISSN: 0940-6719
Elektronische ISSN: 1432-0932
DOI
https://doi.org/10.1007/s00586-008-0746-2

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