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European Spine Journal
Erschienen in: European Spine Journal 1/2012

01.05.2012 | Original Article

Diffusion-weighted MR imaging in differentiation between osteoporotic and neoplastic vertebral fractures

verfasst von: G. Pozzi, C. Garcia Parra, P. Stradiotti, T. V. Tien, A. Luzzati, A. Zerbi

Erschienen in: European Spine Journal | Sonderheft 1/2012

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Abstract

Purpose

To assess the usefulness of magnetic resonance imaging (MRI) with spin-echo echo-planar diffusion-weighted imaging (SE-EPI-DWI) in differentiation between vertebral osteoporotic fractures and pathological neoplastic fractures.

Materials and methods

Thirty-three patients with both osteoporotic or neoplastic vertebral fractures diagnosed with X-ray or TC were studied with MRI exam, (1.5 T unit) with DWI sequences. DWI sequences were qualitatively analyzed. Apparent diffusion coefficient (ADC) values were also determined and compared to the definitive histologic diagnosis.

Results

DWI of neoplastic lesions showed hyperintensity signal in 22 out of 23 cases. Mean ADC value of neoplastic fractures was 1.241 ± 0.4 × 10−3 mm2/s; mean ADC value of osteoporotic fractures was 0.646 ± 0.368 × 10−3 mm2/s. Neoplastic fractures showed ADC values significantly higher than osteoporotic ones (p < 0.001). DWI imaging and histology showed a significant correlation.

Conclusion

DWI provides reliable information to support MRI diagnosis of neoplastic versus osteoporotic fractures. ADC value appears as a useful adjunctive parameter.
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Metadaten
Titel
Diffusion-weighted MR imaging in differentiation between osteoporotic and neoplastic vertebral fractures
verfasst von
G. Pozzi
C. Garcia Parra
P. Stradiotti
T. V. Tien
A. Luzzati
A. Zerbi
Publikationsdatum
01.05.2012
Verlag
Springer-Verlag
Erschienen in
European Spine Journal / Ausgabe Sonderheft 1/2012
Print ISSN: 0940-6719
Elektronische ISSN: 1432-0932
DOI
https://doi.org/10.1007/s00586-012-2227-x

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