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01.08.2015 | Original Article

Surgery and survival outcomes of 30 patients with neurological deficit due to clear cell renal cell carcinoma spinal metastases

verfasst von: Shuai Han, Ting Wang, Dongjie Jiang, Yang Yu, Yu Wang, Wangjun Yan, Wei Xu, Ming Cheng, Wang Zhou, Jianru Xiao

Erschienen in: European Spine Journal | Ausgabe 8/2015

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Abstract

Purpose

The aim of this study was to provide some useful insights into the clinical and imaging presentations, treatment and prognostic factors in patients with neurological deficit caused by clear cell renal cell carcinoma (CCRCC) spinal metastases for the sake of designing individualized therapeutic plans for such patients.

Methods

A total of 30 patients with neurological deficit due to CCRCC spinal metastases who received surgery in our department were identified during an 8-year period from 2003 to 2012 and used for discussion of treatment options for CCRCC spinal metastases on the basis of literature review and our own experience.

Results

Univariate analysis showed that age (≤45 years/>45 years), visceral metastasis, Tomita score (3–5/6–8), Tokuhashi score (4–9/10–12) and radiotherapy were suggested as the potential prognostic factors. However, the multivariate Cox regression model showed that only Tokuhashi score was an independent prognostic factor.

Conclusions

Tokuhashi score 10 or more is a favorable prognostic factor of CCRCC spinal metastasis.

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Titel: Surgery and survival outcomes of 30 patients with neurological deficit due to clear cell renal cell carcinoma spinal metastases
verfasst von: Shuai Han
Ting Wang
Dongjie Jiang
Yang Yu
Yu Wang
Wangjun Yan
Wei Xu
Ming Cheng
Wang Zhou
Jianru Xiao
Publikationsdatum: 01.08.2015
Verlag: Springer Berlin Heidelberg
Erschienen in: European Spine Journal / Ausgabe 8/2015
Print ISSN: 0940-6719
Elektronische ISSN: 1432-0932
DOI: https://doi.org/10.1007/s00586-015-3912-3

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Surgery and survival outcomes of 30 patients with neurological deficit due to clear cell renal cell carcinoma spinal metastases

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Conclusions

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