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01.06.2015 | Original Article

Fear of hypoglycemia: relationship to hypoglycemic risk and psychological factors

verfasst von: Therese Anderbro, Linda Gonder-Frederick, Jan Bolinder, Per-Eric Lins, Regina Wredling, Erik Moberg, Jan Lisspers, Unn-Britt Johansson

Erschienen in: Acta Diabetologica | Ausgabe 3/2015

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Abstract

Objective

The major aims of this study were to examine (1) the association between fear of hypoglycemia (FOH) in adults with type 1 diabetes with demographic, psychological (anxiety and depression), and disease-specific clinical factors (hypoglycemia history and unawareness, A_1c), including severe hypoglycemia (SH), and (2) differences in patient subgroups categorized by level of FOH and risk of SH.

Research design and methods

Questionnaires were mailed to 764 patients with type 1 diabetes including the Swedish translation of the Hypoglycemia Fear Survey (HFS) and other psychological measures including the Perceived Stress Scale, Hospital Anxiety and Depression Scale, Anxiety Sensitivity Index, Social Phobia Scale, and Fear of Complications Scale. A questionnaire to assess hypoglycemia history was also included and A_1c measures were obtained from medical records. Statistical analyses included univariate approaches, multiple stepwise linear regressions, Chi-square t tests, and ANOVAs.

Results

Regressions showed that several clinical factors (SH history, frequency of nocturnal hypoglycemia, self-monitoring) were significantly associated with FOH but R ² increased from 16.25 to 39.2 % when anxiety measures were added to the model. When patients were categorized by level of FOH (low, high) and SH risk (low, high), subgroups showed significant differences in non-diabetes-related anxiety, hypoglycemia history, self-monitoring, and glycemic control.

Conclusion

There is a strong link between FOH and non-diabetes-related anxiety, as well as hypoglycemia history. Comparison of patient subgroups categorized according to level of FOH and SH risk demonstrated the complexity of FOH and identified important differences in psychological and clinical variables, which have implications for clinical interventions.

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Titel: Fear of hypoglycemia: relationship to hypoglycemic risk and psychological factors
verfasst von: Therese Anderbro
Linda Gonder-Frederick
Jan Bolinder
Per-Eric Lins
Regina Wredling
Erik Moberg
Jan Lisspers
Unn-Britt Johansson
Publikationsdatum: 01.06.2015
Verlag: Springer Milan
Erschienen in: Acta Diabetologica / Ausgabe 3/2015
Print ISSN: 0940-5429
Elektronische ISSN: 1432-5233
DOI: https://doi.org/10.1007/s00592-014-0694-8

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Fear of hypoglycemia: relationship to hypoglycemic risk and psychological factors

Abstract

Objective

Research design and methods

Results

Conclusion

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Objective

Research design and methods

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