Erschienen in:
01.02.2016 | Short Communication
Maternal hair metabolome analysis identifies a potential marker of lipid peroxidation in gestational diabetes mellitus
verfasst von:
Xiaoling He, Jamie V. de Seymour, Karolina Sulek, Hongbo Qi, Hua Zhang, Ting-Li Han, Silas G. Villas-Bôas, Philip N. Baker
Erschienen in:
Acta Diabetologica
|
Ausgabe 1/2016
Einloggen, um Zugang zu erhalten
Excerpt
Gestational diabetes mellitus (GDM) is defined as an abnormal glucose tolerance that develops, or is first recognized during pregnancy; the development of GDM markedly increases risks of adverse obstetric and perinatal outcome. The immediate consequences include an increased likelihood of a Caesarean section, hypoglycaemia of the newborn, respiratory distress syndrome, and macrosomia. Longer-term implications of a pregnancy affected by GDM include a substantially increased risk of the mother developing type 2 diabetes postnatally, as well as the offspring having an increased susceptibility to obesity and related metabolic complications in adulthood. Within the Asia–Pacific region there are an estimated 76 million women at risk of having a pregnancy complicated by diabetes, with recent estimates suggesting up to 18 % of pregnancies in China may be complicated by GDM [
1]. …