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Erschienen in: Surgery Today 6/2013

01.06.2013 | Short communication

Visualization of diffusion of the drug solution during aluminum potassium tannic acid injection therapy: a pilot study

verfasst von: Yutaka Yamamoto, Mitsuharu Miwa

Erschienen in: Surgery Today | Ausgabe 6/2013

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Abstract

Sclerotherapy with aluminum potassium tannic acid (ALTA), which was approved in Japan for the treatment of internal hemorrhoids in July 2004 (Takano et al., Int J Colorectal Dis 21:44–51, 2006), has been widely accepted because of its effectiveness and low invasiveness. More than 200,000 patients have received ALTA injection therapy. ALTA is injected directly into 4 points of an internal hemorrhoid (4-step injection) to induce sclerosis and remission of the hemorrhoids, and consequently, resolution of symptoms such as prolapse and bleeding. The precision of the 4-step injection is considered to be a crucial determinant of the success of this therapy and the risk of complications. However, sufficient evidence has not yet been obtained concerning the diffusion and distribution of the injected drug. A pilot study visualized the real-time diffusion/distribution of the drug solution following the 4-step injection, using the ICG (indocyanine green) fluorescence technique, and an infrared camera (Photodynamic EYE; PDE, Hamamatsu Photonics K.K.).
Literatur
1.
Zurück zum Zitat Takano M, Iwadare J, Ohba H, Takamura H, Masuda Y, Matsuo K, et al. Sclerosing therapy of internal hemorrhoids with a novel sclerosing agent. Comparison with ligation and excision. Int J Colorectal Dis. 2006;21:44–51.PubMedCrossRef Takano M, Iwadare J, Ohba H, Takamura H, Masuda Y, Matsuo K, et al. Sclerosing therapy of internal hemorrhoids with a novel sclerosing agent. Comparison with ligation and excision. Int J Colorectal Dis. 2006;21:44–51.PubMedCrossRef
2.
Zurück zum Zitat Hachiro Y, Kunimoto M, Abe T, Kitada M, Ebisawa Y. Aluminum potassium sulfate and tannic acid (ALTA) injection as the mainstay of treatment for internal hemorrhoids. Surg Today. 2011;41(6):806–9.PubMedCrossRef Hachiro Y, Kunimoto M, Abe T, Kitada M, Ebisawa Y. Aluminum potassium sulfate and tannic acid (ALTA) injection as the mainstay of treatment for internal hemorrhoids. Surg Today. 2011;41(6):806–9.PubMedCrossRef
3.
Zurück zum Zitat Shi Z, Zhou J, He X. On treatment of third degree internal hemorrhoids with “Xiaozhiling” injection—a clinical investigation on 1205 cases. J Tradit Chin Med. 1981;1:115–20. Shi Z, Zhou J, He X. On treatment of third degree internal hemorrhoids with “Xiaozhiling” injection—a clinical investigation on 1205 cases. J Tradit Chin Med. 1981;1:115–20.
4.
Zurück zum Zitat Shi Z. Xiaozhiling four-step injection in treating hemorrhoids of stages III and IV—a sclerotherapeutic approach of thrombosing branches of artery rectalis superior. Chin J Tradit W Med. 1997;3:246–9. Shi Z. Xiaozhiling four-step injection in treating hemorrhoids of stages III and IV—a sclerotherapeutic approach of thrombosing branches of artery rectalis superior. Chin J Tradit W Med. 1997;3:246–9.
Metadaten
Titel
Visualization of diffusion of the drug solution during aluminum potassium tannic acid injection therapy: a pilot study
verfasst von
Yutaka Yamamoto
Mitsuharu Miwa
Publikationsdatum
01.06.2013
Verlag
Springer Japan
Erschienen in
Surgery Today / Ausgabe 6/2013
Print ISSN: 0941-1291
Elektronische ISSN: 1436-2813
DOI
https://doi.org/10.1007/s00595-012-0429-9

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