Skip to main content
Erschienen in: Surgery Today 7/2014

01.07.2014 | Review Article

Diagnostic imaging in the preoperative management of lung cancer

verfasst von: Kazuhiro Imai, Yoshihiro Minamiya, Hajime Saito, Satoru Motoyama, Yusuke Sato, Aki Ito, Kei Yoshino, Satoshi Kudo, Shinogu Takashima, Yasushi Kawaharada, Nobuyasu Kurihara, Kimito Orino, Jun-ichi Ogawa

Erschienen in: Surgery Today | Ausgabe 7/2014

Einloggen, um Zugang zu erhalten

Abstract

Surgical resection is the accepted standard of care for patients with non-small cell lung cancer (NSCLC). Several imaging modalities play central roles in the detection and staging of the disease. The aim of this review is to evaluate the utility of computed tomography (CT), magnetic resonance imaging (MRI), positron emission tomography (PET) and PET/CT for NSCLC staging. Radiographic staging refers to the use of CT as a non-invasive diagnostic technique. However, while the vast majority of patients undergo only CT, CT is a notoriously inaccurate means of tumor and nodal staging in many situations. PET/CT clearly improves the staging, particularly nodal staging, compared to CT or PET alone. In addition, as a result of the increased soft-tissue contrast, MRI is superior to CT for distinguishing between tissue characteristics. Endobronchial ultrasound-guided transbronchial needle aspiration (EBUS-TBNA), which is a minimally invasive technique, also has pathological diagnostic potential. Extensive research and the resultant improvements in the understanding of genetics, histology, molecular biology and oncology are transforming our understanding of lung cancer, and it is clear that imaging modalities such as CT, MRI, PET and PET/CT will have an important role in its preoperative management. However, thoracic surgeons should also be aware of the limitations of these techniques.
Literatur
1.
Zurück zum Zitat Parkin DM, Bray F, Ferlay J, Pisani P. Global cancer statistics, 2002. CA Cancer J Clin. 2005;55:74–108.PubMedCrossRef Parkin DM, Bray F, Ferlay J, Pisani P. Global cancer statistics, 2002. CA Cancer J Clin. 2005;55:74–108.PubMedCrossRef
2.
Zurück zum Zitat Jemal A, Bray F, Center MM, Ferlay J, Ward E, Forman D. Global cancer statistics. CA Cancer J Clin. 2011;61:69–90.PubMedCrossRef Jemal A, Bray F, Center MM, Ferlay J, Ward E, Forman D. Global cancer statistics. CA Cancer J Clin. 2011;61:69–90.PubMedCrossRef
3.
Zurück zum Zitat Mountain CF. Revisions in the international system for staging lung cancer. Chest. 1997;111:1710–7.PubMedCrossRef Mountain CF. Revisions in the international system for staging lung cancer. Chest. 1997;111:1710–7.PubMedCrossRef
4.
Zurück zum Zitat Fukui T, Mitsudomi T. Small peripheral lung adenocarcinoma: clinicopathological features and surgical treatment. Surg Today. 2010;40:191–8.PubMedCrossRef Fukui T, Mitsudomi T. Small peripheral lung adenocarcinoma: clinicopathological features and surgical treatment. Surg Today. 2010;40:191–8.PubMedCrossRef
5.
Zurück zum Zitat Sawabata N, Fujii Y, Asamura H, Nomori H, Nakanishi Y, Eguchi K, et al. Lung Cancer in Japan: analysis of Lung Cancer Registry for resected cases in 2004 (in Japanese). Jpn J Lung Cancer. 2010;50:875–88.CrossRef Sawabata N, Fujii Y, Asamura H, Nomori H, Nakanishi Y, Eguchi K, et al. Lung Cancer in Japan: analysis of Lung Cancer Registry for resected cases in 2004 (in Japanese). Jpn J Lung Cancer. 2010;50:875–88.CrossRef
6.
Zurück zum Zitat Downey RJ. Follow-up of patients with completely resected lung cancer. Chest. 1999;115:1487–98.PubMedCrossRef Downey RJ. Follow-up of patients with completely resected lung cancer. Chest. 1999;115:1487–98.PubMedCrossRef
7.
Zurück zum Zitat Dillemans B, Deneffe G, Verschakelen J, Decramer M. Value of computed tomography and mediastinoscopy in preoperative evaluation of mediastinal nodes in non-small cell lung cancer. A study of 569 patients. Eur J Cardiothorac Surg. 1994;8:37–42.PubMedCrossRef Dillemans B, Deneffe G, Verschakelen J, Decramer M. Value of computed tomography and mediastinoscopy in preoperative evaluation of mediastinal nodes in non-small cell lung cancer. A study of 569 patients. Eur J Cardiothorac Surg. 1994;8:37–42.PubMedCrossRef
9.
Zurück zum Zitat Ueda K, Kaneda Y, Saeki K, Fujita N, Zempo N, Esato K. Hilar lymph nodes in N2 disease: survival analysis of patients with non-small cell lung cancers and regional lymph node metastasis. Surg Today. 2002;32:300–4.PubMedCrossRef Ueda K, Kaneda Y, Saeki K, Fujita N, Zempo N, Esato K. Hilar lymph nodes in N2 disease: survival analysis of patients with non-small cell lung cancers and regional lymph node metastasis. Surg Today. 2002;32:300–4.PubMedCrossRef
10.
Zurück zum Zitat Marra A, Hillejan L, Zaboura G, Fujimoto T, Greschuchna D, Stamatis G. Pathologic N1 non-small cell lung cancer: correlation between pattern of lymphatic spread and prognosis. J Thorac Cardiovasc Surg. 2003;125:543–53.PubMedCrossRef Marra A, Hillejan L, Zaboura G, Fujimoto T, Greschuchna D, Stamatis G. Pathologic N1 non-small cell lung cancer: correlation between pattern of lymphatic spread and prognosis. J Thorac Cardiovasc Surg. 2003;125:543–53.PubMedCrossRef
11.
Zurück zum Zitat Fujimoto T, Cassivi SD, Yang P, Barnes SA, Nichols FC, Deschamps C, et al. Completely resected N1 non-small cell lung cancer: factors affecting recurrence and long-term survival. J Thorac Cardiovasc Surg. 2006;132:499–506.PubMedCrossRef Fujimoto T, Cassivi SD, Yang P, Barnes SA, Nichols FC, Deschamps C, et al. Completely resected N1 non-small cell lung cancer: factors affecting recurrence and long-term survival. J Thorac Cardiovasc Surg. 2006;132:499–506.PubMedCrossRef
12.
Zurück zum Zitat Miyoshi K, Mimura T, Iwanaga K, Adachi S, Tsubota N, Okada M. Surgical treatment of clinical N1 non-small cell lung cancer: ongoing controversy over diagnosis and prognosis. Surg Today. 2010;40:428–32.PubMedCrossRef Miyoshi K, Mimura T, Iwanaga K, Adachi S, Tsubota N, Okada M. Surgical treatment of clinical N1 non-small cell lung cancer: ongoing controversy over diagnosis and prognosis. Surg Today. 2010;40:428–32.PubMedCrossRef
13.
Zurück zum Zitat Ambrosini V, Nicolini S, Caroli P, Nanni C, Massaro A, Marzola MC, et al. PET/CT imaging in different types of lung cancer: an overview. Eur J Radiol. 2012;81:988–1001.PubMedCrossRef Ambrosini V, Nicolini S, Caroli P, Nanni C, Massaro A, Marzola MC, et al. PET/CT imaging in different types of lung cancer: an overview. Eur J Radiol. 2012;81:988–1001.PubMedCrossRef
14.
Zurück zum Zitat Silvestri GA, Gould MK, Margolis ML, Tanoue LT, McCrory D, Toloza E, et al. American College of Chest Physicians. Noninvasive staging of non-small cell lung cancer: ACCP evidenced-based clinical practice guidelines (2nd edition). Chest. 2007;132:178–201.CrossRef Silvestri GA, Gould MK, Margolis ML, Tanoue LT, McCrory D, Toloza E, et al. American College of Chest Physicians. Noninvasive staging of non-small cell lung cancer: ACCP evidenced-based clinical practice guidelines (2nd edition). Chest. 2007;132:178–201.CrossRef
15.
Zurück zum Zitat Detterbeck FC, Jantz MA, Wallace M, Vansteenkiste J, Silvestri GA. American College of Chest Physicians. Invasive mediastinal staging of lung cancer. ACCP evidence-based clinical practice guidelines (2nd edition). Chest. 2007;132:202–20.CrossRef Detterbeck FC, Jantz MA, Wallace M, Vansteenkiste J, Silvestri GA. American College of Chest Physicians. Invasive mediastinal staging of lung cancer. ACCP evidence-based clinical practice guidelines (2nd edition). Chest. 2007;132:202–20.CrossRef
16.
Zurück zum Zitat Akiba T, Marushima H, Harada J, Kobayashi S, Morikawa T. Importance of preoperative imaging with 64-row three-dimensional multidetector computed tomography for safer video-assisted thoracic surgery in lung cancer. Surg Today. 2009;39:844–7.PubMedCrossRef Akiba T, Marushima H, Harada J, Kobayashi S, Morikawa T. Importance of preoperative imaging with 64-row three-dimensional multidetector computed tomography for safer video-assisted thoracic surgery in lung cancer. Surg Today. 2009;39:844–7.PubMedCrossRef
17.
Zurück zum Zitat McCaughan BC, Martini N, Bains MS, McCormack PM. Chest wall invasion in carcinoma of the lung: therapeutic and prognostic implications. J Thorac Cardiovasc Surg. 1985;89:836–41.PubMed McCaughan BC, Martini N, Bains MS, McCormack PM. Chest wall invasion in carcinoma of the lung: therapeutic and prognostic implications. J Thorac Cardiovasc Surg. 1985;89:836–41.PubMed
18.
Zurück zum Zitat Grillo HC. Technical considerations in stage III disease: pleural and chest wall involvement. In: Delarue NC, Eschapasse H, editors. International trends in general thoracic surgery, vol. 1st. Philadelphia: WB Saunders; 1985. p. 134–8. Grillo HC. Technical considerations in stage III disease: pleural and chest wall involvement. In: Delarue NC, Eschapasse H, editors. International trends in general thoracic surgery, vol. 1st. Philadelphia: WB Saunders; 1985. p. 134–8.
19.
Zurück zum Zitat Komaki R, Mountain CF, Holbert JM, Garden AS, Shallenberger R, Cox JD, et al. Superior sulcus tumors: treatment selection and results for 85 patients without metastasis (Mo) at presentation. Int J Radiat Oncol Biol Phys. 1990;19:31–6.PubMedCrossRef Komaki R, Mountain CF, Holbert JM, Garden AS, Shallenberger R, Cox JD, et al. Superior sulcus tumors: treatment selection and results for 85 patients without metastasis (Mo) at presentation. Int J Radiat Oncol Biol Phys. 1990;19:31–6.PubMedCrossRef
20.
Zurück zum Zitat Mountain CF. Expanded possibilities for surgical treatment of lung cancer: survival in stage IIIa disease. Chest. 1990;97:1045–51.PubMedCrossRef Mountain CF. Expanded possibilities for surgical treatment of lung cancer: survival in stage IIIa disease. Chest. 1990;97:1045–51.PubMedCrossRef
21.
Zurück zum Zitat Kawaguchi K, Mori S, Usami N, Fukui T, Mitsudomi T, Yokoi K. Preoperative evaluation of the depth of chest wall invasion and the extent of combined resections in lung cancer patients. Lung Cancer. 2009;64:41–4.PubMedCrossRef Kawaguchi K, Mori S, Usami N, Fukui T, Mitsudomi T, Yokoi K. Preoperative evaluation of the depth of chest wall invasion and the extent of combined resections in lung cancer patients. Lung Cancer. 2009;64:41–4.PubMedCrossRef
22.
Zurück zum Zitat Sobin LH, Gospodarowicz MK, Wittekind Ch, editors. TNM classification of malignant tumours. 7th ed. New York: Wiley-Blackwell; 2009. Sobin LH, Gospodarowicz MK, Wittekind Ch, editors. TNM classification of malignant tumours. 7th ed. New York: Wiley-Blackwell; 2009.
23.
Zurück zum Zitat Travis WD, Brambilla E, Rami-Porta R, Vallières E, Tsuboi M, Rusch V, et al. Visceral pleural invasion: pathologic criteria and use of elastic stains: proposal for the 7th edition of the TNM classification for lung cancer. J Thorac Oncol. 2008;3:1384–90.PubMedCrossRef Travis WD, Brambilla E, Rami-Porta R, Vallières E, Tsuboi M, Rusch V, et al. Visceral pleural invasion: pathologic criteria and use of elastic stains: proposal for the 7th edition of the TNM classification for lung cancer. J Thorac Oncol. 2008;3:1384–90.PubMedCrossRef
24.
Zurück zum Zitat Grenier P, Dubary B, Carette MF, Frija G, Musset D, Chastang C. Preoperative thoracic staging of lung cancer: CT and MR evaluation. Diagn Interv Radiol. 1989;1:23–8. Grenier P, Dubary B, Carette MF, Frija G, Musset D, Chastang C. Preoperative thoracic staging of lung cancer: CT and MR evaluation. Diagn Interv Radiol. 1989;1:23–8.
25.
Zurück zum Zitat Uhrmeister P, Allmann KH, Wertzel H, Altehoefer C, Laubenberger J, Hasse J, et al. Chest wall infiltration by lung cancer: value of thin-sectional CT with different reconstruction algorithms. Eur Radiol. 1999;9:1304–9.PubMedCrossRef Uhrmeister P, Allmann KH, Wertzel H, Altehoefer C, Laubenberger J, Hasse J, et al. Chest wall infiltration by lung cancer: value of thin-sectional CT with different reconstruction algorithms. Eur Radiol. 1999;9:1304–9.PubMedCrossRef
26.
Zurück zum Zitat Higashino T, Ohno Y, Takenaka D, Watanabe H, Nogami M, Ohbayashi C, et al. Thin-section multiplanar reformats from multidetector-row CT data: utility for assessment of regional tumor extent in non-small cell lung cancer. Eur J Radiol. 2005;56:48–55.PubMedCrossRef Higashino T, Ohno Y, Takenaka D, Watanabe H, Nogami M, Ohbayashi C, et al. Thin-section multiplanar reformats from multidetector-row CT data: utility for assessment of regional tumor extent in non-small cell lung cancer. Eur J Radiol. 2005;56:48–55.PubMedCrossRef
27.
Zurück zum Zitat Imai K, Minamiya Y, Ishiyama K, Hashimoto M, Saito H, Motoyama S, et al. Use of CT to evaluate pleural invasion in non-small cell lung cancer: measurement of the ratio of the interface between tumor and neighboring structures to maximum tumor diameter. Radiology. 2013;267(2):619–26. Imai K, Minamiya Y, Ishiyama K, Hashimoto M, Saito H, Motoyama S, et al. Use of CT to evaluate pleural invasion in non-small cell lung cancer: measurement of the ratio of the interface between tumor and neighboring structures to maximum tumor diameter. Radiology. 2013;267(2):619–26.
28.
Zurück zum Zitat de Langen AJ, Raijmakers P, Riphagen I, Paul MA, Hoekstra OS. The size of mediastinal lymph nodes and its relation with metastatic involvement: a meta-analysis. Eur J Cardiothorac Surg. 2006;29:26–9.PubMedCrossRef de Langen AJ, Raijmakers P, Riphagen I, Paul MA, Hoekstra OS. The size of mediastinal lymph nodes and its relation with metastatic involvement: a meta-analysis. Eur J Cardiothorac Surg. 2006;29:26–9.PubMedCrossRef
29.
Zurück zum Zitat Staples CA, Müller NL, Miller RR, Evans KG, Nelems B. Mediastinal nodes in bronchogenic carcinoma: comparison between CT and mediastinoscopy. Radiology. 1988;167:367–72.PubMed Staples CA, Müller NL, Miller RR, Evans KG, Nelems B. Mediastinal nodes in bronchogenic carcinoma: comparison between CT and mediastinoscopy. Radiology. 1988;167:367–72.PubMed
30.
Zurück zum Zitat Lewis JW Jr, Pearlberg JL, Beute GH, Alpern M, Kvale PA, Gross BH, et al. Can computed tomography of the chest stage lung cancer? Yes and no. Ann Thorac Surg. 1990;49:591–5.PubMedCrossRef Lewis JW Jr, Pearlberg JL, Beute GH, Alpern M, Kvale PA, Gross BH, et al. Can computed tomography of the chest stage lung cancer? Yes and no. Ann Thorac Surg. 1990;49:591–5.PubMedCrossRef
31.
Zurück zum Zitat Glazer GM, Gross BH, Quint LE, Francis IR, Bookstein FL, Orringer MB. Normal mediastinal lymph nodes: number and size according to American Thoracic Society mapping. Am J Roentgenol. 1985;144:261–5.CrossRef Glazer GM, Gross BH, Quint LE, Francis IR, Bookstein FL, Orringer MB. Normal mediastinal lymph nodes: number and size according to American Thoracic Society mapping. Am J Roentgenol. 1985;144:261–5.CrossRef
32.
Zurück zum Zitat Dales RE, Stark RM, Raman S. Computed tomography to stage lung cancer. Approaching a controversy using meta-analysis. Am Rev Respir Dis. 1990;141:1096–101.PubMedCrossRef Dales RE, Stark RM, Raman S. Computed tomography to stage lung cancer. Approaching a controversy using meta-analysis. Am Rev Respir Dis. 1990;141:1096–101.PubMedCrossRef
33.
Zurück zum Zitat Kramer H, Groen HJ. Current concepts in the mediastinal lymph node staging of nonsmall cell lung cancer. Ann Surg. 2003;238:180–8.PubMedCentralPubMed Kramer H, Groen HJ. Current concepts in the mediastinal lymph node staging of nonsmall cell lung cancer. Ann Surg. 2003;238:180–8.PubMedCentralPubMed
34.
Zurück zum Zitat Dwamena BA, Sonnad SS, Angobaldo JO, Wahl RL. Metastases from non-small cell lung cancer: mediastinal staging in the 1990s—meta-analytic comparison of PET and CT. Radiology. 1999;213:530–6.PubMedCrossRef Dwamena BA, Sonnad SS, Angobaldo JO, Wahl RL. Metastases from non-small cell lung cancer: mediastinal staging in the 1990s—meta-analytic comparison of PET and CT. Radiology. 1999;213:530–6.PubMedCrossRef
35.
Zurück zum Zitat Imai K, Minamiya Y, Saito H, Nakagawa T, Hosono Y, Nanjo H, et al. Accuracy of helical computed tomography for the identification of lymph node metastasis in resectable non-small cell lung cancer. Surg Today. 2008;38:1083–90.PubMedCrossRef Imai K, Minamiya Y, Saito H, Nakagawa T, Hosono Y, Nanjo H, et al. Accuracy of helical computed tomography for the identification of lymph node metastasis in resectable non-small cell lung cancer. Surg Today. 2008;38:1083–90.PubMedCrossRef
36.
Zurück zum Zitat Ohno Y, Hatabu H, Takenaka D, Higashino T, Watanabe H, Ohbayashi C, et al. Metastases in mediastinal and hilar lymph nodes in patients with non-small cell lung cancer: quantitative and qualitative assessment with STIR turbo spin-echo MR imaging. Radiology. 2004;231:872–9.PubMedCrossRef Ohno Y, Hatabu H, Takenaka D, Higashino T, Watanabe H, Ohbayashi C, et al. Metastases in mediastinal and hilar lymph nodes in patients with non-small cell lung cancer: quantitative and qualitative assessment with STIR turbo spin-echo MR imaging. Radiology. 2004;231:872–9.PubMedCrossRef
37.
38.
Zurück zum Zitat Sakai S, Murayama S, Murakami J, Hashiguchi N, Masuda K. Bronchogenic carcinoma invasion of the chest wall: evaluation with dynamic cine MRI during breathing. J Comput Assist Tomogr. 1997;21:595–600.PubMedCrossRef Sakai S, Murayama S, Murakami J, Hashiguchi N, Masuda K. Bronchogenic carcinoma invasion of the chest wall: evaluation with dynamic cine MRI during breathing. J Comput Assist Tomogr. 1997;21:595–600.PubMedCrossRef
39.
Zurück zum Zitat Biederer J. General requirements of MRI of the lung and suggested standard protocols. In: Kauczor HU, editor. MRI of the lung. Berlin: Springer; 2009. p. 3–16.CrossRef Biederer J. General requirements of MRI of the lung and suggested standard protocols. In: Kauczor HU, editor. MRI of the lung. Berlin: Springer; 2009. p. 3–16.CrossRef
40.
Zurück zum Zitat Koyama H, Ohno Y, Kono A, Takenaka D, Maniwa Y, Nishimura Y, et al. Quantitative and qualitative assessment of non-contrast-enhanced pulmonary MR imaging for management of pulmonary nodules in 161 subjects. Eur Radiol. 2008;18:2120–31.PubMedCrossRef Koyama H, Ohno Y, Kono A, Takenaka D, Maniwa Y, Nishimura Y, et al. Quantitative and qualitative assessment of non-contrast-enhanced pulmonary MR imaging for management of pulmonary nodules in 161 subjects. Eur Radiol. 2008;18:2120–31.PubMedCrossRef
41.
Zurück zum Zitat Ohno Y, Koyama H, Dinkel J, Hintze C. Lung cancer. In: Kauczor HU, editor. MRI of the lung. Berlin: Springer; 2009. p. 179–216.CrossRef Ohno Y, Koyama H, Dinkel J, Hintze C. Lung cancer. In: Kauczor HU, editor. MRI of the lung. Berlin: Springer; 2009. p. 179–216.CrossRef
42.
Zurück zum Zitat Ohno Y, Adachi S, Motoyama A, Kusumoto M, Hatabu H, Sugimura K, et al. Multiphase ECG triggered 3D contrast enhanced MR angiography: utility for evaluation of hilar and mediastinal invasion of bronchogenic carcinoma. J Magn Reson Imaging. 2001;13:215–24.PubMedCrossRef Ohno Y, Adachi S, Motoyama A, Kusumoto M, Hatabu H, Sugimura K, et al. Multiphase ECG triggered 3D contrast enhanced MR angiography: utility for evaluation of hilar and mediastinal invasion of bronchogenic carcinoma. J Magn Reson Imaging. 2001;13:215–24.PubMedCrossRef
43.
Zurück zum Zitat Kajiwara N, Akata S, Uchida O, Usuda J, Ohira T, Kawate N, et al. Cine MRI enables better therapeutic planning than CT in cases of possible lung cancer chest wall invasion. Lung Cancer. 2010;69:203–8.PubMedCrossRef Kajiwara N, Akata S, Uchida O, Usuda J, Ohira T, Kawate N, et al. Cine MRI enables better therapeutic planning than CT in cases of possible lung cancer chest wall invasion. Lung Cancer. 2010;69:203–8.PubMedCrossRef
44.
Zurück zum Zitat Akata S, Kajiwara N, Park J, Yoshimura M, Kakizaki D, Abe K, et al. Evaluation of chest wall invasion by lung cancer using respiratory dynamic MRI. J Med Imaging Radiat Oncol. 2008;52:36–9.PubMedCrossRef Akata S, Kajiwara N, Park J, Yoshimura M, Kakizaki D, Abe K, et al. Evaluation of chest wall invasion by lung cancer using respiratory dynamic MRI. J Med Imaging Radiat Oncol. 2008;52:36–9.PubMedCrossRef
45.
Zurück zum Zitat Shiotani S, Sugimura K, Sugihara M, Kawamitsu H, Yamauchi M, Yoshida M, et al. Diagnosis of chest wall invasion by lung cancer: useful criteria for exclusion of the possibility of chest wall invasion with MR imaging. Radiat Med. 2000;18:283–90.PubMed Shiotani S, Sugimura K, Sugihara M, Kawamitsu H, Yamauchi M, Yoshida M, et al. Diagnosis of chest wall invasion by lung cancer: useful criteria for exclusion of the possibility of chest wall invasion with MR imaging. Radiat Med. 2000;18:283–90.PubMed
46.
Zurück zum Zitat Heelan RT, Demas BE, Caravelli JF, Martini N, Bains MS, McCormack PM, et al. Superior sulcus tumors: CT and MR imaging. Radiology. 1989;170:637–41.PubMed Heelan RT, Demas BE, Caravelli JF, Martini N, Bains MS, McCormack PM, et al. Superior sulcus tumors: CT and MR imaging. Radiology. 1989;170:637–41.PubMed
47.
Zurück zum Zitat Pitz CC, de la Rivière AB, van Swieten HA, Duurkens VA, Lammers JW, van den Bosch JM. Surgical treatment of Pancoast tumours. Eur J Cardiothorac Surg. 2004;26:202–8.PubMedCrossRef Pitz CC, de la Rivière AB, van Swieten HA, Duurkens VA, Lammers JW, van den Bosch JM. Surgical treatment of Pancoast tumours. Eur J Cardiothorac Surg. 2004;26:202–8.PubMedCrossRef
48.
Zurück zum Zitat Wittenberg KH, Adkins MC. MR imaging of nontraumatic brachial plexopathies: frequency and spectrum of findings. Radiographics. 2000;20:1023–32.PubMedCrossRef Wittenberg KH, Adkins MC. MR imaging of nontraumatic brachial plexopathies: frequency and spectrum of findings. Radiographics. 2000;20:1023–32.PubMedCrossRef
49.
Zurück zum Zitat Fujimoto K, Edamitsu O, Meno S, Abe T, Honda N, Ogoh Y, et al. MR diagnosis for metastasis or non-metastasis of mediastinal and hilar lymph nodes in cases of primary lung cancer: detectability, signal intensity, and MR-pathologic correlation (in Japanese). Nihon Igaku Hoshasen Gakkai Zasshi. 1995;55:162–71.PubMed Fujimoto K, Edamitsu O, Meno S, Abe T, Honda N, Ogoh Y, et al. MR diagnosis for metastasis or non-metastasis of mediastinal and hilar lymph nodes in cases of primary lung cancer: detectability, signal intensity, and MR-pathologic correlation (in Japanese). Nihon Igaku Hoshasen Gakkai Zasshi. 1995;55:162–71.PubMed
50.
Zurück zum Zitat Takenaka D, Ohno Y, Hatabu H, Ohbayashi C, Yoshimura M, Ohkita Y, et al. Differentiation of metastatic versus non-metastatic mediastinal lymph nodes in patients with non-small cell lung cancer using respiratory-triggered short inversion time inversion recovery (STIR) turbo spin-echo MR imaging. Eur J Radiol. 2002;44:216–24.PubMedCrossRef Takenaka D, Ohno Y, Hatabu H, Ohbayashi C, Yoshimura M, Ohkita Y, et al. Differentiation of metastatic versus non-metastatic mediastinal lymph nodes in patients with non-small cell lung cancer using respiratory-triggered short inversion time inversion recovery (STIR) turbo spin-echo MR imaging. Eur J Radiol. 2002;44:216–24.PubMedCrossRef
51.
Zurück zum Zitat Ohno Y, Koyama H, Nogami M, Takenaka D, Yoshikawa T, Yoshimura M, et al. STIR turbo SE MR imaging vs. coregistered FDG-PET/CT: quantitative and qualitative assessment of N-stage in non-small-cell lung cancer patients. J Magn Reson Imaging. 2007;26:1071–80.PubMedCrossRef Ohno Y, Koyama H, Nogami M, Takenaka D, Yoshikawa T, Yoshimura M, et al. STIR turbo SE MR imaging vs. coregistered FDG-PET/CT: quantitative and qualitative assessment of N-stage in non-small-cell lung cancer patients. J Magn Reson Imaging. 2007;26:1071–80.PubMedCrossRef
52.
Zurück zum Zitat Al-Sarraf N, Gately K, Lucey J, Wilson L, McGovern E, Young V. Lymph node staging by means of positron emission tomography is less accurate in non-small cell lung cancer patients with enlarged lymph nodes: analysis of 1,145 lymph nodes. Lung Cancer. 2008;60:62–8.PubMedCrossRef Al-Sarraf N, Gately K, Lucey J, Wilson L, McGovern E, Young V. Lymph node staging by means of positron emission tomography is less accurate in non-small cell lung cancer patients with enlarged lymph nodes: analysis of 1,145 lymph nodes. Lung Cancer. 2008;60:62–8.PubMedCrossRef
53.
Zurück zum Zitat Yi CA, Shin KM, Lee KS, Kim BT, Kim H, Kwon OJ, et al. Non-small cell lung cancer staging: efficacy comparison of integrated PET/CT versus 3.0-T whole-body MR imaging. Radiology. 2008;248:632–42.PubMedCrossRef Yi CA, Shin KM, Lee KS, Kim BT, Kim H, Kwon OJ, et al. Non-small cell lung cancer staging: efficacy comparison of integrated PET/CT versus 3.0-T whole-body MR imaging. Radiology. 2008;248:632–42.PubMedCrossRef
54.
Zurück zum Zitat Qu X, Huang X, Yan W, Wu L, Dai K. A meta-analysis of 18FDG-PET–CT, 18FDG-PET, MRI and bone scintigraphy for diagnosis of bone metastases in patients with lung cancer. Eur J Radiol. 2012;81:1007–15.PubMedCrossRef Qu X, Huang X, Yan W, Wu L, Dai K. A meta-analysis of 18FDG-PET–CT, 18FDG-PET, MRI and bone scintigraphy for diagnosis of bone metastases in patients with lung cancer. Eur J Radiol. 2012;81:1007–15.PubMedCrossRef
55.
Zurück zum Zitat DiPerna CA, Wood DE. Surgical management of T3 and T4 lung cancer. Clin Cancer Res. 2005;11:5038–44.CrossRef DiPerna CA, Wood DE. Surgical management of T3 and T4 lung cancer. Clin Cancer Res. 2005;11:5038–44.CrossRef
56.
Zurück zum Zitat Chao F, Zhang H. PET/CT in the staging of the non-small-cell lung cancer. Biomed Biotechnol. 2012;2012:783739. Chao F, Zhang H. PET/CT in the staging of the non-small-cell lung cancer. Biomed Biotechnol. 2012;2012:783739.
57.
Zurück zum Zitat Takenaka T, Yano T, Morodomi Y, Ito K, Miura N, Kawano D, et al. Prediction of true-negative lymph node metastasis in clinical IA non-small cell lung cancer by measuring standardized uptake values on positron emission tomography. Surg Today. 2012;42:934–9.PubMedCrossRef Takenaka T, Yano T, Morodomi Y, Ito K, Miura N, Kawano D, et al. Prediction of true-negative lymph node metastasis in clinical IA non-small cell lung cancer by measuring standardized uptake values on positron emission tomography. Surg Today. 2012;42:934–9.PubMedCrossRef
58.
Zurück zum Zitat Lardinois D, Weder W, Hany TF, Kamel EM, Korom S, Seifert B, et al. Staging of non-small-cell lung cancer with integrated positron-emission tomography and computed tomography. N Engl J Med. 2003;348:2500–7.PubMedCrossRef Lardinois D, Weder W, Hany TF, Kamel EM, Korom S, Seifert B, et al. Staging of non-small-cell lung cancer with integrated positron-emission tomography and computed tomography. N Engl J Med. 2003;348:2500–7.PubMedCrossRef
59.
Zurück zum Zitat Kaira K, Oriuchi N, Shimizu K, Tominaga H, Yanagitani N, Sunaga N, et al. 18F-FMT uptake seen within primary cancer on PET helps predict outcome of non-small cell lung cancer. J Nucl Med. 2009;50:1770–6.PubMedCrossRef Kaira K, Oriuchi N, Shimizu K, Tominaga H, Yanagitani N, Sunaga N, et al. 18F-FMT uptake seen within primary cancer on PET helps predict outcome of non-small cell lung cancer. J Nucl Med. 2009;50:1770–6.PubMedCrossRef
60.
Zurück zum Zitat Kaira K, Oriuchi N, Shimizu K, Imai H, Tominaga H, Yanagitani N, et al. Comparison of l-type amino acid transporter 1 expression and l-[3-18F]-α-methyl tyrosine uptake in outcome of non-small cell lung cancer. Nucl Med Biol. 2010;37:911–6.PubMedCrossRef Kaira K, Oriuchi N, Shimizu K, Imai H, Tominaga H, Yanagitani N, et al. Comparison of l-type amino acid transporter 1 expression and l-[3-18F]-α-methyl tyrosine uptake in outcome of non-small cell lung cancer. Nucl Med Biol. 2010;37:911–6.PubMedCrossRef
61.
Zurück zum Zitat Changlai SP, Tsai SC, Chou MC, Ho YJ, Kao CH. Whole body 18 F-2-deoxyglucose positron emission tomography to restage non-small cell lung cancer. Oncol Rep. 2001;8:337–9.PubMed Changlai SP, Tsai SC, Chou MC, Ho YJ, Kao CH. Whole body 18 F-2-deoxyglucose positron emission tomography to restage non-small cell lung cancer. Oncol Rep. 2001;8:337–9.PubMed
62.
Zurück zum Zitat Weng E, Tran L, Rege S, Safa A, Sadeghi A, Juillard G, et al. Accuracy and clinical impact of mediastinal lymph node staging with FDG-PET imaging in potentially resectable lung cancer. Am J Clin Oncol. 2000;23:47–52.PubMedCrossRef Weng E, Tran L, Rege S, Safa A, Sadeghi A, Juillard G, et al. Accuracy and clinical impact of mediastinal lymph node staging with FDG-PET imaging in potentially resectable lung cancer. Am J Clin Oncol. 2000;23:47–52.PubMedCrossRef
63.
Zurück zum Zitat De Wever W, Ceyssens S, Mortelmans L, Stroobants S, Marchal G, Bogaert J, et al. Additional value of PET–CT in the staging of lung cancer: comparison with CT alone, PET alone and visual correlation of PET and CT. Eur Radiol. 2007;17:23–32.PubMedCrossRef De Wever W, Ceyssens S, Mortelmans L, Stroobants S, Marchal G, Bogaert J, et al. Additional value of PET–CT in the staging of lung cancer: comparison with CT alone, PET alone and visual correlation of PET and CT. Eur Radiol. 2007;17:23–32.PubMedCrossRef
64.
Zurück zum Zitat Heyneman LE, Patz EF. PET imaging in patients with bronchioloalveolar cell carcinoma. Lung Cancer. 2002;38:261–6.PubMedCrossRef Heyneman LE, Patz EF. PET imaging in patients with bronchioloalveolar cell carcinoma. Lung Cancer. 2002;38:261–6.PubMedCrossRef
65.
Zurück zum Zitat Daniels CE, Lowe VJ, Aubry MC, Allen MS, Jett JR. The utility of fluorodeoxyglucose positron emission tomography in the evaluation of carcinoid tumors presenting as pulmonary nodules. Chest. 2007;131:255–60.PubMedCrossRef Daniels CE, Lowe VJ, Aubry MC, Allen MS, Jett JR. The utility of fluorodeoxyglucose positron emission tomography in the evaluation of carcinoid tumors presenting as pulmonary nodules. Chest. 2007;131:255–60.PubMedCrossRef
66.
Zurück zum Zitat Behzadi A, Ung Y, Lowe V, Deschamps C. The role of positron emission tomography in the management of non-small cell lung cancer. Can J Surg. 2009;52:235–42.PubMedCentralPubMed Behzadi A, Ung Y, Lowe V, Deschamps C. The role of positron emission tomography in the management of non-small cell lung cancer. Can J Surg. 2009;52:235–42.PubMedCentralPubMed
67.
Zurück zum Zitat Lv YL, Yuan DM, Wang K, Miao XH, Qian Q, Wei SZ, et al. Diagnostic performance of integrated positron emission tomography/computed tomography for mediastinal lymph node staging in non-small cell lung cancer: a bivariate systematic review and meta-analysis. J Thorac Oncol. 2011;6:1350–8.PubMedCrossRef Lv YL, Yuan DM, Wang K, Miao XH, Qian Q, Wei SZ, et al. Diagnostic performance of integrated positron emission tomography/computed tomography for mediastinal lymph node staging in non-small cell lung cancer: a bivariate systematic review and meta-analysis. J Thorac Oncol. 2011;6:1350–8.PubMedCrossRef
68.
Zurück zum Zitat Cronin P, Dwamena BA, Kelly AM, Carlos RC. Solitary pulmonary nodules: meta-analytic comparison of cross-sectional imaging modalities for diagnosis of malignancy. Radiology. 2008;246:772–82.PubMedCrossRef Cronin P, Dwamena BA, Kelly AM, Carlos RC. Solitary pulmonary nodules: meta-analytic comparison of cross-sectional imaging modalities for diagnosis of malignancy. Radiology. 2008;246:772–82.PubMedCrossRef
69.
Zurück zum Zitat Erasmus JJ, McAdams HP, Rossi SE, Goodman PC, Coleman RE, Patz EF. FDG PET of pleural effusions in patients with non-small cell lung cancer. AJR Am J Roentgenol. 2000;175:245–9.PubMedCrossRef Erasmus JJ, McAdams HP, Rossi SE, Goodman PC, Coleman RE, Patz EF. FDG PET of pleural effusions in patients with non-small cell lung cancer. AJR Am J Roentgenol. 2000;175:245–9.PubMedCrossRef
70.
Zurück zum Zitat Gupta NC, Rogers JS, Graeber GM, Gregory JL, Waheed U, Mullet D, et al. Clinical role of F-18 fluorodeoxyglucose positron emission tomography imaging in patients with lung cancer and suspected malignant pleural effusion. Chest. 2002;122:1918–24.PubMedCrossRef Gupta NC, Rogers JS, Graeber GM, Gregory JL, Waheed U, Mullet D, et al. Clinical role of F-18 fluorodeoxyglucose positron emission tomography imaging in patients with lung cancer and suspected malignant pleural effusion. Chest. 2002;122:1918–24.PubMedCrossRef
71.
Zurück zum Zitat Toaff JS, Metser U, Gottfried M, Gur O, Deeb ME, Lievshitz G, et al. Differentiation between malignant and benign pleural effusion in patients with extra-pleural primary malignancies: assessment with positron emission tomography–computed tomography. Invest Radiol. 2005;40:204–9.PubMedCrossRef Toaff JS, Metser U, Gottfried M, Gur O, Deeb ME, Lievshitz G, et al. Differentiation between malignant and benign pleural effusion in patients with extra-pleural primary malignancies: assessment with positron emission tomography–computed tomography. Invest Radiol. 2005;40:204–9.PubMedCrossRef
72.
Zurück zum Zitat Duysinx BC, Larock MP, Nguyen D, Corhay JL, Bury T, Hustinx R, et al. 18F-FDG PET imaging in assessing exudative pleural effusions. Nucl Med Commun. 2006;27:971–6.PubMedCrossRef Duysinx BC, Larock MP, Nguyen D, Corhay JL, Bury T, Hustinx R, et al. 18F-FDG PET imaging in assessing exudative pleural effusions. Nucl Med Commun. 2006;27:971–6.PubMedCrossRef
73.
Zurück zum Zitat Shim SS, Lee KS, Kim BT, Chung MJ, Lee EJ, Han J, et al. Non-small cell lung cancer: prospective comparison of integrated FDG PET/CT and CT alone for preoperative staging. Radiology. 2005;236:1011–9.PubMedCrossRef Shim SS, Lee KS, Kim BT, Chung MJ, Lee EJ, Han J, et al. Non-small cell lung cancer: prospective comparison of integrated FDG PET/CT and CT alone for preoperative staging. Radiology. 2005;236:1011–9.PubMedCrossRef
74.
Zurück zum Zitat Gupta NC, Graeber GM, Bishop HA. Comparative efficacy of positron emission tomography with fluorodeoxyglucose in evaluation of small (1 cm), intermediate (1 to 3 cm), and large (3 cm) lymph node lesions. Chest. 2000;117:773–8.PubMedCrossRef Gupta NC, Graeber GM, Bishop HA. Comparative efficacy of positron emission tomography with fluorodeoxyglucose in evaluation of small (1 cm), intermediate (1 to 3 cm), and large (3 cm) lymph node lesions. Chest. 2000;117:773–8.PubMedCrossRef
75.
Zurück zum Zitat Adams K, Shah PL, Edmonds L, Lim E. Test performance of endobronchial ultrasound and transbronchial needle aspiration biopsy for mediastinal staging in patients with lung cancer: systematic review and meta-analysis. Thorax. 2009;64:757–62.PubMedCrossRef Adams K, Shah PL, Edmonds L, Lim E. Test performance of endobronchial ultrasound and transbronchial needle aspiration biopsy for mediastinal staging in patients with lung cancer: systematic review and meta-analysis. Thorax. 2009;64:757–62.PubMedCrossRef
76.
Zurück zum Zitat Zhang R, Ying K, Shi L, Zhang L, Zhou L. Combined endobronchial and endoscopic ultrasound-guided fine needle aspiration for mediastinal lymph node staging of lung cancer: a meta-analysis. Eur J Cancer. 2013;49(8):1860–7. Zhang R, Ying K, Shi L, Zhang L, Zhou L. Combined endobronchial and endoscopic ultrasound-guided fine needle aspiration for mediastinal lymph node staging of lung cancer: a meta-analysis. Eur J Cancer. 2013;49(8):1860–7.
77.
Zurück zum Zitat Eschmann SM, Friedel G, Paulsen F, Budach W, Harer-Mouline C, Dohmen BM, et al. FDG PET for staging of advanced non-small cell lung cancer prior to neoadjuvant radio-chemotherapy. Eur J Nucl Med Mol Imaging. 2002;29:804–8.PubMedCrossRef Eschmann SM, Friedel G, Paulsen F, Budach W, Harer-Mouline C, Dohmen BM, et al. FDG PET for staging of advanced non-small cell lung cancer prior to neoadjuvant radio-chemotherapy. Eur J Nucl Med Mol Imaging. 2002;29:804–8.PubMedCrossRef
78.
Zurück zum Zitat Seltzer MA, Yap CS, Silverman DH, Meta J, Schiepers C, Phelps ME, et al. The impact of PET on the management of lung cancer: the referring physician’s perspective. J Nucl Med. 2002;43:752–6.PubMed Seltzer MA, Yap CS, Silverman DH, Meta J, Schiepers C, Phelps ME, et al. The impact of PET on the management of lung cancer: the referring physician’s perspective. J Nucl Med. 2002;43:752–6.PubMed
79.
Zurück zum Zitat Erasmus JJ, Patz EF Jr, McAdams HP, Murray JG, Herndon J, Coleman RE, et al. Evaluation of adrenal masses in patients with bronchogenic carcinoma using 18F-fluorodeoxyglucose positron emission tomography. AJR Am J Roentgenol. 1997;168:1357–60.PubMedCrossRef Erasmus JJ, Patz EF Jr, McAdams HP, Murray JG, Herndon J, Coleman RE, et al. Evaluation of adrenal masses in patients with bronchogenic carcinoma using 18F-fluorodeoxyglucose positron emission tomography. AJR Am J Roentgenol. 1997;168:1357–60.PubMedCrossRef
80.
Zurück zum Zitat Gulyás B, Halldin C. New PET radiopharmaceuticals beyond FDG for brain tumor imaging. Q J Nucl Med Mol Imaging. 2012;56:173–90.PubMed Gulyás B, Halldin C. New PET radiopharmaceuticals beyond FDG for brain tumor imaging. Q J Nucl Med Mol Imaging. 2012;56:173–90.PubMed
81.
Zurück zum Zitat Aquino SL, Asmuth JC, Alpert NM, Halpern EF, Fischman AJ. Improved radiologic staging of lung cancer with 2-[18F]-fluoro-2-deoxy-d-glucose-positron emission tomography and computed tomography registration. J Comput Assist Tomogr. 2003;27:479–84.PubMedCrossRef Aquino SL, Asmuth JC, Alpert NM, Halpern EF, Fischman AJ. Improved radiologic staging of lung cancer with 2-[18F]-fluoro-2-deoxy-d-glucose-positron emission tomography and computed tomography registration. J Comput Assist Tomogr. 2003;27:479–84.PubMedCrossRef
82.
Zurück zum Zitat Kelly RF, Tran T, Holmstrom A, Murar J, Segurola RJ Jr. Accuracy and cost-effectiveness of [18F]-2-fluoro-deoxy-d-glucose-positron emission tomography scan in potentially resectable non-small cell lung cancer. Chest. 2004;125:1413–23.PubMedCrossRef Kelly RF, Tran T, Holmstrom A, Murar J, Segurola RJ Jr. Accuracy and cost-effectiveness of [18F]-2-fluoro-deoxy-d-glucose-positron emission tomography scan in potentially resectable non-small cell lung cancer. Chest. 2004;125:1413–23.PubMedCrossRef
83.
Zurück zum Zitat Pozo-Rodríguez F, Martín de Nicolás JL, Sánchez-Nistal MA, Maldonado A, García de Barajas S, Calero-García R, et al. Accuracy of helical computed tomography and [18F] fluorodeoxyglucose positron emission tomography for identifying lymph node mediastinal metastases in potentially resectable non-small-cell lung cancer. J Clin Oncol. 2005;23:8348–56.PubMedCrossRef Pozo-Rodríguez F, Martín de Nicolás JL, Sánchez-Nistal MA, Maldonado A, García de Barajas S, Calero-García R, et al. Accuracy of helical computed tomography and [18F] fluorodeoxyglucose positron emission tomography for identifying lymph node mediastinal metastases in potentially resectable non-small-cell lung cancer. J Clin Oncol. 2005;23:8348–56.PubMedCrossRef
Metadaten
Titel
Diagnostic imaging in the preoperative management of lung cancer
verfasst von
Kazuhiro Imai
Yoshihiro Minamiya
Hajime Saito
Satoru Motoyama
Yusuke Sato
Aki Ito
Kei Yoshino
Satoshi Kudo
Shinogu Takashima
Yasushi Kawaharada
Nobuyasu Kurihara
Kimito Orino
Jun-ichi Ogawa
Publikationsdatum
01.07.2014
Verlag
Springer Japan
Erschienen in
Surgery Today / Ausgabe 7/2014
Print ISSN: 0941-1291
Elektronische ISSN: 1436-2813
DOI
https://doi.org/10.1007/s00595-013-0660-z

Weitere Artikel der Ausgabe 7/2014

Surgery Today 7/2014 Zur Ausgabe

Leitlinien kompakt für die Allgemeinmedizin

Mit medbee Pocketcards sicher entscheiden.

Seit 2022 gehört die medbee GmbH zum Springer Medizin Verlag

Facharzt-Training Allgemeinmedizin

Die ideale Vorbereitung zur anstehenden Prüfung mit den ersten 24 von 100 klinischen Fallbeispielen verschiedener Themenfelder

Mehr erfahren

Update Allgemeinmedizin

Bestellen Sie unseren Fach-Newsletter und bleiben Sie gut informiert.