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Erschienen in: Surgery Today 1/2016

01.01.2016 | Original Article

A lower neutrophil to lymphocyte ratio is closely associated with catarrhal appendicitis versus severe appendicitis

verfasst von: Takayuki Shimizu, Mitsuru Ishizuka, Keiichi Kubota

Erschienen in: Surgery Today | Ausgabe 1/2016

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Abstract

Purpose

Catarrhal appendicitis (CA) could be treated effectively with antibiotics in some patients because of the milder inflammation associated with this form of appendicitis. Although several trials have compared surgery with antibiotic therapy for acute appendicitis (AA), the indications for antibiotic therapy remain controversial.

Methods

The subjects of this study were 342 patients who underwent appendectomy at our hospital between January, 2000 and March, 2013. The patients were divided into two groups based on the severity of their appendicitis: Group A comprised patients with severe appendicitis and Group B comprised patients with CA. Statistical analyses were performed to assess the clinical features associated with CA.

Results

Multivariate analysis of the eight clinical features correlated with CA according to univariate analysis revealed that the neutrophil to lymphocyte ratio (NLR) (<5/>5), age (<38/>38 years), fever (<38/>38 °C), white blood cell count (<11.5/>11.5 × 103/mm3) and serum level of C-reactive protein (<110/>110 mg/L) were significantly associated with CA. The NLR (<5/>5) (OR 0.421; 95 % CI 0.218–0.811; P = 0.010) was the most useful predictor of CA, because the area under the ROC curve of NLR was the lowest of all these features.

Conclusion

The preoperative NLR in patients undergoing appendectomy is closely associated with CA.
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Metadaten
Titel
A lower neutrophil to lymphocyte ratio is closely associated with catarrhal appendicitis versus severe appendicitis
verfasst von
Takayuki Shimizu
Mitsuru Ishizuka
Keiichi Kubota
Publikationsdatum
01.01.2016
Verlag
Springer Japan
Erschienen in
Surgery Today / Ausgabe 1/2016
Print ISSN: 0941-1291
Elektronische ISSN: 1436-2813
DOI
https://doi.org/10.1007/s00595-015-1125-3

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