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Surgery Today

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20.06.2016 | Review Article

Subsequent biliary cancer originating from remnant intrapancreatic bile ducts after cyst excision: a literature review

verfasst von: Yoshiaki Mizuguchi, Yoshiharu Nakamura, Eiji Uchida

Erschienen in: Surgery Today | Ausgabe 6/2017

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Abstract

Purpose

There are sporadic reports of cancers developing in the remnant intrapancreatic bile duct tissues of patients with a history of primary choledochal cyst excision. The objective of this review is to study the clinical course of patients who develop subsequent biliary cancer originating from the remnant intrapancreatic bile ducts after cyst excision.

Methods

We describe a total of 17 cases (male:female 5:11; mean age 39.5 years), including the present case, from a review of the medical literature.

Results

Type I, type Iva, and unknown-type choledochal cysts according to the Todani classification were reported in nine, five, and three cases, respectively. The mean time to the development of subsequent cancer was 13.6 years. With the exception of one case, all of the cases (seven/eight cases) had elevated levels of serum CEA and/or CA19-9. Computed tomography was useful for detecting tumors (9/10 cases). Despite aggressive treatment, the cumulative survival rate after treatment was approximately 40 % at 1 year, with a mean survival duration of 12 months.

Conclusion

Cancer may develop up to 10 years after choledochal cyst excision, indicating the need for life-long follow-up in this patient population.

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Titel: Subsequent biliary cancer originating from remnant intrapancreatic bile ducts after cyst excision: a literature review
verfasst von: Yoshiaki Mizuguchi
Yoshiharu Nakamura
Eiji Uchida
Publikationsdatum: 20.06.2016
Verlag: Springer Japan
Erschienen in: Surgery Today / Ausgabe 6/2017
Print ISSN: 0941-1291
Elektronische ISSN: 1436-2813
DOI: https://doi.org/10.1007/s00595-016-1366-9

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Subsequent biliary cancer originating from remnant intrapancreatic bile ducts after cyst excision: a literature review

Abstract

Purpose

Methods

Results

Conclusion

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Conclusion

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